المؤلفون: Matthew L. Freedman, Mark Pomerantz, Orsolya Rusz, Zsofia Sztupinszki, Sándor Spisák, Viktoria Tisza, Marcin Krzystanek, Miklos Diossy, Judit Borcsok, Zoltan Szallasi, István Csabai

المصدر: Clin Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Poly(ADP-ribose) Polymerase Inhibitors, Biology, medicine.disease_cause, Article, Germline, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate, Exome Sequencing, Biomarkers, Tumor, medicine, Humans, Homologous Recombination, Gene, Exome sequencing, BRCA2 Protein, Mutation, BRCA1 Protein, Prostatic Neoplasms, Prognosis, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, Homologous recombination

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab2fd003cb36f7c422a938b5eac7bb6
https://doi.org/10.1158/1078-0432.ccr-19-2135

المؤلفون: Thomas B.K. Watkins, Emilia L. Lim, Selvaraju Veeriah, István Csabai, Maria Greco, Nicholas McGranahan, Gareth A. Wilson, Stefan Boeing, Zoltan Szallasi, Jiri Bartek, Dhruva Biswas, Dijana Djureinovic, Maise Al Bakir, Allan Hackshaw, Charles Swanton, Christopher Abbosh, Rachel Rosenthal, Crispin T. Hiley, Javier Herrero, Krisztián Papp, Kevin Litchfield, Patrick Micke, Judit Moldvay, Balazs Dome, Arul M. Chinnaiyan, Yin Wu, Linnea La Fleur, Marcin Skrzypski, János Fillinger, Mariam Jamal-Hanjani, Marcin Krzystanek, Johan Botling, Nicolai Juul Birkbak, David Allan Moore, Hans Brunnström

المصدر: Biswas, D, Birkbak, N J, Rosenthal, R, Hiley, C T, Lim, E L, Papp, K, Boeing, S, Krzystanek, M, Djureinovic, D, La Fleur, L, Greco, M, Döme, B, Fillinger, J, Brunnström, H, Wu, Y, Moore, D A, Skrzypski, M, Abbosh, C, Litchfield, K, Al Bakir, M, Watkins, T B K, Veeriah, S, Wilson, G A, Jamal-Hanjani, M, Moldvay, J, Botling, J, Chinnaiyan, A M, Micke, P, Hackshaw, A, Bartek, J, Csabai, I, Szallasi, Z, Herrero, J, McGranahan, N, Swanton, C & TRACERx Consortium 2019, ' A clonal expression biomarker associates with lung cancer mortality ', Nature Medicine, vol. 25, no. 10, pp. 1540-1548 . https://doi.org/10.1038/s41591-019-0595-z

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, medicine.medical_specialty, Lung Neoplasms, Tumour heterogeneity, DNA Copy Number Variations, Disease, Biology, General Biochemistry, Genetics and Molecular Biology, Disease-Free Survival, Article, Transcriptome, Clonal Evolution, 03 medical and health sciences, Genetic Heterogeneity, 0302 clinical medicine, Risk Factors, Internal medicine, Exome Sequencing, medicine, Biomarkers, Tumor, Humans, Exome, Lung cancer, Exome sequencing, Aged, Genetic heterogeneity, Cancer, General Medicine, medicine.disease, Prognosis, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2225be7c4547fd49cd0909f53c27198
https://pure.au.dk/portal/da/publications/a-clonal-expression-biomarker-associates-with-lung-cancer-mortality(a2adabfd-14ed-486e-b04b-03d3515e134f).html

المؤلفون: Marcin Krzystanek, Valéria Jósa, Ferenc Salamon, Zsolt Baranyai, Zoltan Szallasi, Aron Charles Eklund, Attila Zaránd

المصدر: International Journal of Surgery. 18:1-6

مصطلحات موضوعية: Male, medicine.medical_specialty, Colorectal cancer, Gastroenterology, Postoperative Complications, Predictive Value of Tests, Internal medicine, medicine, Humans, Platelet, Postoperative Period, Survival analysis, Aged, Retrospective Studies, Aged, 80 and over, Thrombocytosis, Hungary, Predictive marker, Platelet Count, business.industry, Retrospective cohort study, General Medicine, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Primary tumor, Surgery, Predictive value of tests, Female, Colorectal Neoplasms, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad2fd562ecd7b3ae7e38f912bee01c0
https://doi.org/10.1016/j.ijsu.2015.03.005

المؤلفون: D. Sinkó, Valéria Jósa, Kristóf Dede, Aron Charles Eklund, V. Szarvas, Ferenc Salamon, Marcin Krzystanek, F. Jakab, Zoltan Szallasi, Attila Marcell Szász, Zsolt Baranyai, Emese Irma Ágoston

المصدر: Thrombosis and Haemostasis. 112:483-490

مصطلحات موضوعية: Blood Platelets, Male, 0301 basic medicine, medicine.medical_specialty, Pathology, Prognostic factor, Multivariate analysis, Colorectal cancer, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Biomarkers, Tumor, Humans, Medicine, Platelet, Lymphocytes, Aged, Neoplasm Staging, Retrospective Studies, Platelet lymphocyte ratio, Thrombocytosis, Platelet Count, business.industry, Carcinoma, Liver Neoplasms, Hazard ratio, Hematology, Middle Aged, Platelet Activation, Prognosis, medicine.disease, Survival Analysis, Hepatic metastasis, digestive system diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689939a6d89b00cd23c16a3fb825cea0
https://doi.org/10.1160/th13-08-0632

المؤلفون: Marcin Krzystanek, Judit Zámborszky, Judit Z. Gervai, Charles Swanton, János M. Szalai-Gindl, Andrea L. Richardson, Bernadett Szikriszt, Orsolya Pipek, Zoltan Szallasi, Dezső Ribli, Dávid Szüts, István Csabai, Ádám Póti

المصدر: Oncogene
Zamborszky, J, Szikriszt, B, Gervai, J Z, Pipek, O, Poti, A, Krzystanek, M, Ribli, D, Szalai-Gindl, J M, Csabai, I, Szallasi, Z I, Swanton, C, Richardson, A L & Szuets, D 2017, ' Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions ', Oncogene, vol. 36, no. 6, pp. 746-755 . https://doi.org/10.1038/onc.2016.243

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, endocrine system diseases, Mutant, Mutagenesis (molecular biology technique), Biology, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, SDG 3 - Good Health and Well-being, Genetics, medicine, Animals, Humans, skin and connective tissue diseases, Molecular Biology, BRCA2 Protein, Mutation, Mutation Spectra, BRCA1 Protein, Point mutation, Genomics, Methyl methanesulfonate, 030104 developmental biology, chemistry, Mutagenesis, Original Article, Female, Erratum, Homologous recombination, Chickens, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618e1240e32b12194169749a0779ba8c
https://pubmed.ncbi.nlm.nih.gov/28650471

المؤلفون: Celine Lefebvre, Charles Swanton, Aron Charles Eklund, Mariam Jamal-Hanjani, Cecilia Engel Thomas, Andrea Marion Marquard, Francesco Favero, Zoltan Szallasi, Nicolai Juul Birkbak, Seema Shafi, Charles Ferté, Fabrice Andre, Marcin Krzystanek, Gareth A. Wilson

المساهمون: Center for Biological Sequence Analysis [Lyngby], Technical University of Denmark [Lyngby] (DTU), Cancer Research UK Lung Cancer Centre of Excellence [Londres, Royaume-Uni], University College of London [London] (UCL), Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de médecine oncologique [Gustave Roussy], Institut Gustave Roussy (IGR), Cancer Research UK London Research Institute, Children's Hospital Informatics Program at the Harvard-MIT Division of Health Sciences and Technology [Boston, MA, États-Unis] (CHIP@HST), Harvard Medical School [Boston] (HMS), This work was supported by the European Commission 7th Framework Programme [HEALTH-2010-F2-259303], the Danish Council for Independent Research [09-073053/FSS], the Breast Cancer Research Foundation [to ZS], the Villum Kann Rasmussen Foundation [to NJB], the Danish Cancer Society [to ACE] and the Novo Nordisk Foundation. The mutation and SCNA data used to develop the classifiers was obtained from the Sanger Institute Catalogue Of Somatic Mutations In Cancer [15] web site, http://cancer.sanger.ac.uk/cosmic., European Project: 259303,EC:FP7:HEALTH,FP7-HEALTH-2010-two-stage,PREDICT(2011), Bodescot, Myriam, Predicting individual response and resistance to VEGFR/mTOR pathway therapeutic intervention using biomarkers discovered through tumour functional genomics - PREDICT - - EC:FP7:HEALTH2011-01-01 - 2014-12-31 - 259303 - VALID, Danmarks Tekniske Universitet = Technical University of Denmark (DTU), University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH)

المصدر: BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2015, 8 (1), pp.58. ⟨10.1186/s12920-015-0130-0⟩
BMC Medical Genomics, 2015, 8 (1), pp.58. ⟨10.1186/s12920-015-0130-0⟩
Marquard, A M, Birkbak, N J, Thomas, C E, Favero, F, Krzystanek, M, Lefebvre, C, Ferté, C, Jamal-Hanjani, M, Wilson, G A, Shafi, S, Swanton, C, André, F, Szallasi, Z I & Eklund, A C 2015, ' TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen ', BMC Medical Genomics, vol. 8, no. 58 . https://doi.org/10.1186/s12920-015-0130-0

مصطلحات موضوعية: Nonsynonymous substitution, Male, Lung Neoplasms, [SDV.CAN]Life Sciences [q-bio]/Cancer, Breast Neoplasms, Computational biology, Biology, Bioinformatics, Polymorphism, Single Nucleotide, Cancer of unknown primary, 03 medical and health sciences, 0302 clinical medicine, Text mining, Germline mutation, SDG 3 - Good Health and Well-being, [SDV.CAN] Life Sciences [q-bio]/Cancer, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Databases, Genetic, Genetics, medicine, Cancer genomics, Humans, Point Mutation, Genetics(clinical), Lung cancer, Genetics (clinical), 030304 developmental biology, 0303 health sciences, COSMIC cancer database, business.industry, Point mutation, medicine.disease, 3. Good health, Random forest, Technical Advance, Organ Specificity, 030220 oncology & carcinogenesis, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Female, business, Mutations, Cancer of unknown primary origin, Genes, Neoplasm

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b47863004cc96ed59f81440c04e1b59
https://pubmed.ncbi.nlm.nih.gov/26429708

المؤلفون: Valéria Jósa, Balazs Tihanyi, Ferenc Salamon, Zsolt Baranyai, Zoltan Szallasi, Kamilla Szilagyi, Tamás Vass, Marcin Krzystanek, Viktória Juhász, László Harsányi, Tamas Lang

المصدر: Pathology oncology research : POR. 21(4)

مصطلحات موضوعية: Oncology, Male, Cancer Research, medicine.medical_specialty, Surgical margin, Colorectal cancer, Adenocarcinoma, Pathology and Forensic Medicine, Metastasis, Risk Factors, Internal medicine, medicine, Hepatectomy, Humans, Survival rate, Aged, Neoplasm Staging, Retrospective Studies, Thrombocytosis, business.industry, Liver Neoplasms, Cancer, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Prognosis, Adenocarcinoma, Mucinous, Survival Rate, Multivariate Analysis, Female, business, Colorectal Neoplasms, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4752e6e35b7784439af89c68efe9c15
https://pubmed.ncbi.nlm.nih.gov/25761795

المؤلفون: Sander Kelderman, Christian U. Blank, Martin Gore, Andrew Furness, Zoltan Szallasi, Patricia M. M. B. Soetekouw, Marcin Krzystanek, Alexandra Renn, Rob R. H. van den Brom, Ellen Kapiteijn, Ton N. Schumacher, James Larkin, Geke A. P. Hospers, Jan Willem B. de Groot, Rob L. H. Jansen, Bianca Heemskerk, John B. A. G. Haanen, Alfonsus J. M. van den Eertwegh, Edward Fiets, Harm van Tinteren, Paul Lorigan

المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS), Medical oncology, CCA - Innovative therapy, Interne Geneeskunde, MUMC+: MA Hematologie (9), RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy

المصدر: Cancer Immunology Immunotherapy, 63(5), 449-458. SPRINGER
Cancer Immunology, Immunotherapy, 63(5), 449-458
Cancer Immunology, Immunotherapy
Kelderman, S, Heemskerk, B, van Tinteren, H, van den Brom, R R H, Hospers, G A P, van den Eertwegh, A J M, Kapiteijn, E W, de Groot, J W B, Soetekouw, P, Jansen, R L, Fiets, E, Furness, A J S, Renn, A, Krzystanek, M, Szallasi, Z, Lorigan, P, Gore, M E, Schumacher, T N M, Haanen, J B A G, Larkin, J M G & Blank, C U 2014, ' Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma ', Cancer Immunology and Immunotherapy, vol. 63, no. 5, pp. 449-458 . https://doi.org/10.1007/s00262-014-1528-9
Cancer Immunology and Immunotherapy, 63(5), 449-458. Springer Science and Business Media Deutschland GmbH
Cancer Immunology Immunotherapy, 63(5), 449-458. Springer

مصطلحات موضوعية: Oncology, Male, Cancer Research, Skin Neoplasms, Kaplan-Meier Estimate, Immunology and Allergy, Melanoma, Aged, 80 and over, education.field_of_study, IMPROVED SURVIVAL, Antibodies, Monoclonal, Lactate dehydrogenase, Middle Aged, CANCER, LYMPHOCYTE, Treatment Outcome, SAFETY, Cohort, Female, Immunotherapy, medicine.drug, Adult, medicine.medical_specialty, Adolescent, GLYCOLYSIS, Immunology, Population, Ipilimumab, Disease-Free Survival, Young Adult, Internal medicine, Blocking antibody, REGRESSION, ANTI-PD-1, medicine, Biomarkers, Tumor, Humans, education, Adverse effect, Aged, L-Lactate Dehydrogenase, business.industry, Biomarker, medicine.disease, Surgery, Clinical trial, ANTIBODY, Cutaneous melanoma, EXPERIENCE, EXPANDED ACCESS PROGRAM, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24387360207bf4bd110dd4619fb5db15
https://doi.org/10.1007/s00262-014-1528-9

المؤلفون: Zsolt, Baranyai, Valéria, Jósa, Marcin, Krzystanek, Aron C, Eklund, A Marcell, Szász, Zoltán, Szállási

المصدر: Magyar sebeszet. 66(6)

مصطلحات موضوعية: Male, Thrombocytosis, Platelet Count, Kaplan-Meier Estimate, Middle Aged, Prognosis, Disease-Free Survival, Predictive Value of Tests, Risk Factors, Humans, Female, Colorectal Neoplasms, Aged, Neoplasm Staging, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::3b5dbfcba8c453760f0c6e9185fcda75
https://pubmed.ncbi.nlm.nih.gov/24333978

المؤلفون: Marco Gerlinger, Martin Gore, Claudio R. Santos, Lisa Pickering, James Larkin, Charles Swanton, Muhammad A. Khattak, Farrah Bakr, Zoltan Szallasi, Marcin Krzystanek

المصدر: Khattak, M A, Bakr, F, Krzystanek, M, Szallasi, Z I, Gerlinger, M, Santos, C, Swanton, C, Pickering, L M, Gore, M E & Larkin, J M G 2013, ' Prognostic and Predictive Markers in Metastatic Renal Cell Carcinoma ', Journal of Clinical Oncology, vol. 31, no. 7, pp. 20971-972 . https://doi.org/10.1200/JCO.2012.46.9353

مصطلحات موضوعية: Oncology, Male, Cancer Research, medicine.medical_specialty, medicine.drug_class, Antineoplastic Agents, Pharmacology, Tyrosine-kinase inhibitor, Biomarkers, Pharmacological, Renal cell carcinoma, Internal medicine, medicine, Humans, Progression-free survival, Carcinoma, Renal Cell, Sirolimus, Everolimus, L-Lactate Dehydrogenase, business.industry, Sunitinib, TOR Serine-Threonine Kinases, Hazard ratio, medicine.disease, Temsirolimus, Kidney Neoplasms, Axitinib, Female, business, medicine.drug, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111560031840fbb9d6ac6e66ee5c6b32
https://pubmed.ncbi.nlm.nih.gov/23565533