المؤلفون: Caldwell, Nicola, Afshar, Rana, Baragaña, Beatriz, Bustinduy, Amaya L, Caffrey, Conor R, Collins, James J, Fusco, Daniela, Garba, Amadou, Gardner, Mark, Gomes, Mireille, Hoffmann, Karl F, Hsieh, Michael, Lo, Nathan C, McNamara, Case W, Nono, Justin Komguep, Padalino, Gilda, Read, Kevin D, Roestenberg, Meta, Spangenberg, Thomas, Specht, Sabine, Gilbert, Ian H

المصدر: ACS Infectious Diseases. 9(5)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Orphan Drug, Vector-Borne Diseases, Infectious Diseases, Rare Diseases, Digestive Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, London, Schistosomiasis, Praziquantel, Anthelmintics, Schistosoma, schistosomiasis, neglected tropical disease, infectious disease, drug discovery, therapeutic s, anthelmintic s, target product profile, anthelmintics, therapeutics, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/17m2f4vh

المؤلفون: Tyagi, Rahul, Bulman, Christina A, Cho-Ngwa, Fidelis, Fischer, Chelsea, Marcellino, Chris, Arkin, Michelle R, McKerrow, James H, McNamara, Case W, Mahoney, Matthew, Tricoche, Nancy, Jawahar, Shabnam, Janetka, James W, Lustigman, Sara, Sakanari, Judy, Mitreva, Makedonka

المصدر: Pathogens (Basel, Switzerland). 10(1)

مصطلحات موضوعية: anthelmintics, filarial nematodes, in vitro, macrofilaricides, parasitic nematodes, target class repurposing, whole worm assay, Immunology, Medical Microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9z3250qp

المؤلفون: Tyagi, Rahul, Bulman, Christina A, Cho-Ngwa, Fidelis, Fischer, Chelsea, Marcellino, Chris, Arkin, Michelle R, McKerrow, James H, McNamara, Case W, Mahoney, Matthew, Tricoche, Nancy, Jawahar, Shabnam, Janetka, James W, Lustigman, Sara, Sakanari, Judy, Mitreva, Makedonka

المصدر: Pathogens. 10(1)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Microbiology, Immunology, Medical Microbiology, Biotechnology, Vector-Borne Diseases, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, parasitic nematodes, filarial nematodes, whole worm assay, in vitro, target class repurposing, anthelmintics, macrofilaricides, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9z3250qp

المؤلفون: Antonova-Koch, Yevgeniya, Meister, Stephan, Abraham, Matthew, Luth, Madeline R, Ottilie, Sabine, Lukens, Amanda K, Sakata-Kato, Tomoyo, Vanaerschot, Manu, Owen, Edward, Jado, Juan Carlos, Maher, Steven P, Calla, Jaeson, Plouffe, David, Zhong, Yang, Chen, Kaisheng, Chaumeau, Victor, Conway, Amy J, McNamara, Case W, Ibanez, Maureen, Gagaring, Kerstin, Serrano, Fernando Neria, Eribez, Korina, Taggard, Cullin McLean, Cheung, Andrea L, Lincoln, Christie, Ambachew, Biniam, Rouillier, Melanie, Siegel, Dionicio, Nosten, François, Kyle, Dennis E, Gamo, Francisco-Javier, Zhou, Yingyao, Llinás, Manuel, Fidock, David A, Wirth, Dyann F, Burrows, Jeremy, Campo, Brice, Winzeler, Elizabeth A

المصدر: Science. 362(6419)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, HIV/AIDS, Infectious Diseases, Vector-Borne Diseases, Rare Diseases, Malaria, Orphan Drug, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Antimalarials, Chemoprevention, Drug Discovery, Drug Evaluation, Preclinical, Humans, Mitochondria, Plasmodium, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7nt3b34h

المؤلفون: Zeeman, Anne-Marie, van Amsterdam, Sandra M, McNamara, Case W, der Wel, Annemarie Voorberg-van, Klooster, Els J, van den Berg, Alexander, Remarque, Edmond J, Plouffe, David M, van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J, Chatterjee, Arnab K, Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A, Leroy, Didier, Campo, Brice, Diagana, Thierry T, Yeung, Bryan KS, Thomas, Alan W, Kocken, Clemens HM

المصدر: Antimicrobial Agents and Chemotherapy. 58(3)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Orphan Drug, Digestive Diseases, Liver Disease, Malaria, Prevention, Infectious Diseases, Rare Diseases, Vector-Borne Diseases, Biotechnology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Animals, Antimalarials, Drug Evaluation, Preclinical, Female, Hepatocytes, Imidazoles, In Vitro Techniques, Liver, Macaca mulatta, Mice, Mice, Inbred ICR, Plasmodium cynomolgi, Pyrazines, Sporozoites, Microbiology, Pharmacology and Pharmaceutical Sciences, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3fd2d5tk

المؤلفون: Zeeman, Anne-Marie, van Amsterdam, Sandra M, McNamara, Case W, Voorberg-van der Wel, Annemarie, Klooster, Els J, van den Berg, Alexander, Remarque, Edmond J, Plouffe, David M, van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J, Chatterjee, Arnab K, Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A, Leroy, Didier, Campo, Brice, Diagana, Thierry T, Yeung, Bryan KS, Thomas, Alan W, Kocken, Clemens HM

المصدر: Antimicrobial agents and chemotherapy. 58(3)

مصطلحات موضوعية: Liver, Hepatocytes, Animals, Mice, Inbred ICR, Macaca mulatta, Mice, Plasmodium cynomolgi, Sporozoites, Malaria, Imidazoles, Pyrazines, Antimalarials, Drug Evaluation, Preclinical, Female, In Vitro Techniques, Inbred ICR, Drug Evaluation, Preclinical, Microbiology, Medical Microbiology, Pharmacology and Pharmaceutical Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3fd2d5tk

المؤلفون: McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Nagle, Advait, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A

المصدر: Nature. 504(7479)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Orphan Drug, Prevention, Infectious Diseases, Rare Diseases, Malaria, Vector-Borne Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, 1-Phosphatidylinositol 4-Kinase, Adenosine Triphosphate, Animals, Binding Sites, Cytokinesis, Drug Resistance, Fatty Acids, Female, Hepatocytes, Humans, Imidazoles, Life Cycle Stages, Macaca mulatta, Male, Models, Biological, Models, Molecular, Phosphatidylinositol Phosphates, Plasmodium, Pyrazoles, Quinoxalines, Reproducibility of Results, Schizonts, rab GTP-Binding Proteins, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/31f5h8fc