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المؤلفون: Caiyong Lai, Guo Chen, Yan Chen, Naite Xi, Ling Tian, Mingrong Cao, Yongchang Zhang, Qi Feng, Congcong Chen, Shengbin Lin, Yanguan Guo, Li Yu, Jiaxin Tian, Jinye Mi, Jun Fan, Fan Zhang
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 7, Pp 643-652 (2021)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: 0301 basic medicine, DNA Replication, Cancer Research, Antimetabolites, Antineoplastic, Ribonucleoside Diphosphate Reductase, DNA damage, Cell, Mechanistic Target of Rapamycin Complex 2, Deoxycytidine, Histones, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Ribonucleotide Reductases, medicine, EGFR, Epidermal growth factor receptor, Humans, Phosphorylation, NSCLC, Non-small cell lung cancer, dNTP, deoxyribonucleotide triphosphates, Ribonucleotide reductase, mTORC2, RC254-282, Original Research, Chemistry, DNA replication, Cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, DNA Replication Fork, DSB, Double-strand break, Gemcitabine, DNA replication stress, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer cell, Cancer research, RNR, Ribonucleotide reductase, medicine.drug, DNA Damage, Protein Binding, Signal Transduction
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2
المؤلفون: Stephen D. Larson, McKenzie Carter, Galadriel Hovel-Miner
المصدر: Parasitology
مصطلحات موضوعية: 0301 basic medicine, melarsoprol, T. brucei, 030106 microbiology, trypanothione, Trypanothione, γ-glutamylcysteine synthetase, Melarsoprol, Biology, ribonucleotide reductase, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Eflornithine, medicine, Trypanosomatids, chemistry.chemical_classification, DNA synthesis, fexinidazole, Cell cycle, Antitrypanosomal drugs, 030104 developmental biology, Infectious Diseases, Ribonucleotide reductase, Enzyme, Biochemistry, chemistry, Animal Science and Zoology, Parasitology, cell cycle, medicine.drug, Research Article
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المؤلفون: Maren de Vries, Fabrice Bailly, Philippe Cotelle, Ramanjit Kaur, Meike Dittmann, Sheena Faye Garcia, Hailey V Goldberg, Bearach Miwatani-Minter, Gergely Róna, Hui Wang, András Zeke, Ning Zheng, Nathaniel R. Landau, Thomas R. Hinds, Michele Pagano, Austin Schinlever, Didier Desmaële
المصدر: Cell Death and Differentiation
مصطلحات موضوعية: Exonuclease, Ribonucleotide, viruses, In silico, Population, Viral Nonstructural Proteins, Virus Replication, medicine.disease_cause, Antiviral Agents, Microbiology, Article, medicine, Humans, Viral Regulatory and Accessory Proteins, Human coronavirus OC43, education, Molecular Biology, Coronavirus, education.field_of_study, Alanine, biology, SARS-CoV-2, virus diseases, Cell Biology, biology.organism_classification, Virology, Adenosine Monophosphate, respiratory tract diseases, DNA repair enzymes, A549 Cells, Exoribonucleases, Sofalcone, biology.protein, Infectious diseases, Proofreading, medicine.drug
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المصدر: Molecular Cancer Therapeutics. 20:655-664
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Ribonucleoside Diphosphate Reductase, Combination therapy, Anthracycline, Population, Mice, Nude, Estrogen receptor, Apoptosis, Triple Negative Breast Neoplasms, Ribonucleotide reductase inhibitor, Mice, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, medicine, Animals, Humans, Doxorubicin, Molecular Targeted Therapy, education, Triple-negative breast cancer, Cell Proliferation, education.field_of_study, business.industry, NF-kappa B, medicine.disease, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Tumor Suppressor Protein p53, business, Signal Transduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc21dbe7b8e6d1740b3ff0fc629a1c1a
https://doi.org/10.1158/1535-7163.mct-20-0373 -
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المؤلفون: Hiroshi Hijioka, Masatatsu Yamamoto, Tatsuhiko Furukawa, Kentaro Minami, Takayuki Ishida, Norifumi Nakamura, Kohichi Kawahara, Noriho Shinagawa
المصدر: Oral Science International. 18:169-177
مصطلحات موضوعية: Ribonucleotide reductase, Otorhinolaryngology, Chemistry, Tranilast, Cancer research, medicine, Gemcitabine resistance, Gemcitabine, medicine.drug
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المؤلفون: Peiyu Lin, Anindita Basu, Ella Perrault, David James, Issam Ben-Sahra, Shreya Budhiraja, Cheol Park, Atique Ahmed, Jack Shireman, Sebastian Pott, Shivani Baisiwala, Andrew Zolp, Eunüs S. Ali
المصدر: Neuro-Oncology. 23:vi81-vi82
مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, Temozolomide, Chemistry, DNA damage, DNA repair, medicine.disease, Ribonucleotide reductase, Oncology, medicine, Cancer research, Ribonucleotide reductase regulatory subunit M2, Nucleotide, Neurology (clinical), Gene, medicine.drug, Glioblastoma
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3e5733688f7873f43a35356f97107787
https://doi.org/10.1093/neuonc/noab196.318 -
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المؤلفون: Eunus S. Ali, Shreya Budhiraja, Charles David James, Ella Perrault, Anindita Basu, Luke Tomes, Sebastian Pott, Issam Ben-Sahra, Atique Ahmed, Andrew Zolp, Shivani Baisiwala, Peiyu Lin, Isabelle Preddy, Jack Shireman, Cheol Park
مصطلحات موضوعية: education.field_of_study, Temozolomide, DNA damage, Population, Cancer, Biology, medicine.disease, chemistry.chemical_compound, Ribonucleotide reductase, chemistry, In vivo, Cancer research, medicine, Deoxyguanosine, Deoxycytidine, education, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8165007756b8f62ca40b6d1b8f2eb995
https://doi.org/10.1101/2021.11.23.469785 -
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المؤلفون: Zonghui Yuan, Cuirong Wu, Yufeng Gu, Haihong Hao, Lulu Huang, Guyue Cheng, Junhong Huang
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 12218, p 12218 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22مصطلحات موضوعية: Salmonella, medicine.drug_class, QH301-705.5, transcriptome sequencing, medicine.disease_cause, Article, Catalysis, Microbiology, Evolution, Molecular, Inorganic Chemistry, resistance, Bacterial Proteins, Drug Resistance, Bacterial, Enrofloxacin, medicine, Physical and Theoretical Chemistry, Biology (General), Gene, Molecular Biology, QD1-999, Spectroscopy, Purine ribonucleotide biosynthetic process, Chemistry, sub-inhibitory concentration, Organic Chemistry, IMP biosynthetic process, General Medicine, Quinolone, Computer Science Applications, Salmonella enteritidis, Biosynthetic process, Porin, Efflux, enrofloxacin, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Wenge Zhu, Yi Zhang, Zongzhu Li, Jing Sun, Yongming Li, Zhou Bo, Wei Zhou, Yun Yen, Zhiyong Han, Melvin L. DePamphilis, Yunxiao Meng, Chi-Wei Chen, Shuya Hu
المصدر: Oncogene
مصطلحات موضوعية: 0301 basic medicine, DNA Replication, Models, Molecular, Cancer Research, DHS, DNA damage, pancreatic cancer, Mice, Nude, Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Gene duplication, Ribonucleotide Reductases, Stilbenes, Genetics, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Cell Proliferation, gemcitabine resistance, DNA replication, HCT116 Cells, Xenograft Model Antitumor Assays, Gemcitabine, 3. Good health, Molecular Docking Simulation, Protein Subunits, 030104 developmental biology, Ribonucleotide reductase, Proteasome, Apoptosis, Cell culture, 030220 oncology & carcinogenesis, RRM2, Cancer research, Female, medicine.drug
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المؤلفون: Yang Li, Qunwei Xu, Yang Liu, Yimin Niu, Zhiyu He, Ming Xu, Jianhua Zhu, Yuxia Zhang, Huihui Shi
المصدر: Journal of Materials Chemistry B. 8:332-342
مصطلحات موضوعية: Lung Neoplasms, endocrine system diseases, Endosome, Biomedical Engineering, Metal Nanoparticles, chemistry.chemical_element, Antineoplastic Agents, Platinum nanoparticles, Deoxycytidine, In vivo, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, General Materials Science, Platinum, Drug Carriers, Chemistry, General Chemistry, General Medicine, Gemcitabine, Drug Liberation, Ribonucleotide reductase, A549 Cells, Cancer cell, Cancer research, Nanocarriers, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89c9f9f57221d0cd138228a47ab8482
https://doi.org/10.1039/c9tb02055a