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1
المؤلفون: Peng Lv, Shi-Liang Huang, Zhen-Quan Liu, Ning Wang, Zhi-Shu Huang, Chun-Li Xia
المصدر: Bioorganic & Medicinal Chemistry. 26:4693-4705
مصطلحات موضوعية: 0301 basic medicine, Swine, Amyloid beta, Clinical Biochemistry, Tau protein, Pharmaceutical Science, tau Proteins, Protein aggregation, Blood–brain barrier, 01 natural sciences, Biochemistry, Protein Aggregates, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Microscopy, Electron, Transmission, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Biology, Amyloid beta-Peptides, Microscopy, Confocal, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Surface Plasmon Resonance, Peptide Fragments, In vitro, 0104 chemical sciences, Acridone, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Blood-Brain Barrier, Drug Design, Tacrine, biology.protein, Molecular Medicine, Acridones, Central Nervous System Agents, medicine.drug
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2
المؤلفون: Pei-Fen Yao, Jie-Bin Ou, Du-Chao Zhou, Honggen Wang, Zhi-Shu Huang, Hua-Ting Xie, Cheng-Cheng Liang, Shi-Liang Huang, Shuo-Bin Chen, Yan-Wen Mai
المصدر: Bioorganic chemistry. 114
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Bioassay, Potency, Humans, Topoisomerase II Inhibitors, Cytotoxicity, Poly-ADP-Ribose Binding Proteins, Molecular Biology, IC50, Etoposide, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Topoisomerase, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, DNA Topoisomerases, Type II, Cell culture, biology.protein, Drug Screening Assays, Antitumor, medicine.drug
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3
المؤلفون: Shuo-Bin Chen, Jie-Bin Ou, Jia-Heng Tan, Ding Li, Zhi-Shu Huang, Tian-Miao Ou, Liu-Lan Shen, Lian-Quan Gu, Shi-Liang Huang, Zhi-Hong Huang, Wei-Bin Wu
المصدر: European Journal of Medicinal Chemistry. 46:3339-3347
مصطلحات موضوعية: Lung Neoplasms, Cell Survival, Topoisomerase Inhibitors, medicine.drug_class, Stereochemistry, Adenocarcinoma of Lung, Antineoplastic Agents, Adenocarcinoma, Topoisomerase-I Inhibitor, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Antigens, Neoplasm, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, Telomerase, Etoposide, Pyrans, Pharmacology, Nasopharyngeal Carcinoma, biology, Topoisomerase, Carcinoma, Organic Chemistry, Quinones, Nasopharyngeal Neoplasms, DNA, General Medicine, DNA-Binding Proteins, DNA Topoisomerases, Type II, DNA Topoisomerases, Type I, chemistry, Biochemistry, Enzyme inhibitor, Pyran, biology.protein, Drug Screening Assays, Antitumor, Sesquiterpenes, Topoisomerase inhibitor, Naphthoquinones, Plasmids, medicine.drug
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4
المؤلفون: Zhi-Shu Huang, Ding Li, Yan-Ping Li, Yan He, Wen Luo, Lian-Quan Gu, Shi-Liang Huang
المصدر: European Journal of Medicinal Chemistry. 46:2609-2616
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Crystallography, X-Ray, Chemical synthesis, Antioxidants, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Humans, Structure–activity relationship, Butyrylcholinesterase, Cholinesterase, Pharmacology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Active site, Stereoisomerism, General Medicine, Acetylcholinesterase, Peptide Fragments, chemistry, Enzyme inhibitor, Tacrine, biology.protein, Cholinesterase Inhibitors, medicine.drug
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5
المؤلفون: Hong Liang, Hao-Tao Zhao, Huang Tang, Zhi-Shu Huang, Shi-Liang Huang, Shu-Ming Zhong, Jiang-Ke Qin, Zhen-Feng Chen, Li-Zhen Zhao
المصدر: ChemInform. 43
مصطلحات موضوعية: Aché, Acridine derivatives, General Medicine, Acetylcholinesterase, language.human_language, chemistry.chemical_compound, chemistry, Biochemistry, β amyloid, Tacrine, language, medicine, Binding site, Butyrylcholinesterase, medicine.drug
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6
المؤلفون: Hao-Tao Zhao, Jiang-Ke Qin, Shu-Ming Zhong, Zhen-Feng Chen, Zhi-Shu Huang, Hong Liang, Li-Zhen Zhao, Huang Tang, Shi-Liang Huang
المصدر: European journal of medicinal chemistry. 46(10)
مصطلحات موضوعية: Amyloid, Aporphines, Aché, Stereochemistry, Models, Biological, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Moiety, Animals, Humans, Horses, Binding site, Butyrylcholinesterase, Pharmacology, Amyloid beta-Peptides, Organic Chemistry, General Medicine, Acetylcholinesterase, language.human_language, In vitro, chemistry, Biochemistry, Blood-Brain Barrier, Tacrine, Electrophorus, language, Cholinesterase Inhibitors, Linker, medicine.drug
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7
المؤلفون: Lian-Quan Gu, Ding Li, Wen Luo, Jia-Heng Tan, Yan-Ping Li, Tian-Miao Ou, Yan He, Shi-Liang Huang, Zhi-Shu Huang
المصدر: Bioorganicmedicinal chemistry. 19(2)
مصطلحات موضوعية: Amyloid beta, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Drug Discovery, medicine, Moiety, Computer Simulation, Binding site, Molecular Biology, Butyrylcholinesterase, Amyloid beta-Peptides, Binding Sites, biology, Organic Chemistry, Active site, Benzene, Acetylcholinesterase, Peptide Fragments, Kinetics, chemistry, Tacrine, Drug Design, biology.protein, Curcumin, Molecular Medicine, Cholinesterase Inhibitors, medicine.drug