نتائج البحث - "Gyun Min Lee"

1

Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture

المؤلفون: Tae Kwang Ha, Gyun Min Lee, Dong-Il Kim, Lise Marie Grav, Che Lin Kim

المصدر: Biotechnology advances. 54

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b99352cb3b5f61d1d6ae168a580386a
https://pubmed.ncbi.nlm.nih.gov/34480988

View record from ScienceDirect

2

Multiplex secretome engineering enhances recombinant protein production and purity

المؤلفون: Bernhard O. Palsson, Austin W. T. Chiang, Johnny Arnsdorf, Marianne Decker, Sanne Schoffelen, Tune Wulff, Lasse Ebdrup Pedersen, Helene Faustrup Kildegaard, Stefan Kol, Tanja Lyholm Jensen, Jahir M. Gutierrez, Gyun Min Lee, Bjørn G. Voldborg, Anders Holmgaard Hansen, Helen O. Masson, Daniel Ley, Nathan E. Lewis

المصدر: Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Kol, S, Ley, D, Wulff, T, Decker, M, Arnsdorf, J, Schoffelen, S, Hansen, A H, Jensen, T L, Gutierrez, J M, Chiang, A W T, Masson, H O, Palsson, B O, Voldborg, B G, Pedersen, L E, Kildegaard, H F, Min Lee, G & Lewis, N E 2020, ' Multiplex secretome engineering enhances recombinant protein production and purity ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-15866-w
Nature Communications

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, medicine.drug_class, Science, Cell, General Physics and Astronomy, CHO Cells, Biologics, Monoclonal antibody, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Antibodies, 03 medical and health sciences, Gene Knockout Techniques, Cricetulus, 010608 biotechnology, Monoclonal, medicine, Protein biosynthesis, Computational models, Animals, Multiplex, lcsh:Science, Biological Products, Chromatography, Multidisciplinary, biology, Chemistry, Chinese hamster ovary cell, Antibodies, Monoclonal, High-Throughput Nucleotide Sequencing, General Chemistry, Recombinant Proteins, 030104 developmental biology, Secretory protein, medicine.anatomical_structure, Biochemistry, Metabolic Engineering, Cell culture, biology.protein, lcsh:Q, Synthetic Biology, Antibody, Rituximab, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39eafb13b29626fb0af0e6200e0258ea
https://escholarship.org/uc/item/6dr7w8j6

3

Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies

المؤلفون: Gyun Min Lee, Seunghyeon Shin, Soo Min Noh

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Noh, S M, Shin, S & Min Lee, G 2018, ' Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies ', Scientific Reports, vol. 8, 5361 . https://doi.org/10.1038/s41598-018-23720-9
Scientific Reports

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, medicine.drug_class, lcsh:Medicine, CHO Cells, Monoclonal antibody, 01 natural sciences, Article, law.invention, Metabolic engineering, Recombinant protein therapy, 03 medical and health sciences, Gene Knockout Techniques, Cricetulus, law, Ammonia, Glutamate-Ammonia Ligase, 010608 biotechnology, Glutamine synthetase, Methionine Sulfoximine, medicine, Animals, Lactic Acid, lcsh:Science, Gene, Multidisciplinary, biology, Chemistry, Chinese hamster ovary cell, lcsh:R, Antibodies, Monoclonal, Molecular biology, Clone Cells, Reverse transcription polymerase chain reaction, 030104 developmental biology, biology.protein, Recombinant DNA, lcsh:Q, Antibody

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850e46418627573f9aa3ff250d013eb2
http://link.springer.com/article/10.1038/s41598-018-23720-9

Find this article in full text from ProQuest

4

Comprehensive characterization of dihydrofolate reductase‐mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies

المؤلفون: Sang Yoon Lee, Gyun Min Lee, Minhye Baek

المصدر: Biotechnology Journal. 16:2000351

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f388961609b3c3eb344866038ab2474
https://doi.org/10.1002/biot.202000351

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5

Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies

المؤلفون: Da Young Yu, Gyun Min Lee, Sang Yoon Lee

المصدر: Biotechnology and bioengineering. 115(5)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58fb2a78d8ca25d8ba6946d09bb1919
https://pubmed.ncbi.nlm.nih.gov/29359789

View record at Wiley

6

Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

المؤلفون: Shangzhong Li, Lise Marie Grav, Bernhard O. Palsson, Michael J. Betenbaugh, Amir Feizi, Deniz Baycin Hizal, Gyun Min Lee, Nathan E. Lewis, Daniel Ley, Jens Nielsen, Bjørn G. Voldborg, Jahir M. Gutierrez, Helene Faustrup Kildegaard, Thomas Beuchert Kallehauge, Hooman Hefzi

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature communications, vol 11, iss 1
Gutierrez, J M, Feizi, A, Li, S, Kallehauge, T B, Hefzi, H, Grav, L M, Ley, D, Baycin Hizal, D, Betenbaugh, M J, Voldborg, B G, Kildegaard, H F, Min Lee, G, Palsson, B O, Nielsen, J & Lewis, N E 2020, ' Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion ', Nature Communications, vol. 11, no. 1, 68 . https://doi.org/10.1038/s41467-019-13867-y

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, General Physics and Astronomy, Bone Morphogenetic Protein 2, 01 natural sciences, Genome, Mice, lcsh:Science, Mammals, 0303 health sciences, Multidisciplinary, Secretory Pathway, Chinese hamster ovary cell, 030302 biochemistry & molecular biology, Recombinant Proteins, Cell biology, Networks and systems biology, Biopharmaceutical, Gene Knockdown Techniques, Biotechnology, medicine.drug_class, Science, 1.1 Normal biological development and functioning, Systems biology, CHO Cells, Biology, Monoclonal antibody, General Biochemistry, Genetics and Molecular Biology, Article, Vaccine Related, 03 medical and health sciences, Metabolomics, Cricetulus, Underpinning research, Biodefense, 010608 biotechnology, medicine, Gene silencing, Animals, Humans, Secretion, Computer Simulation, Secretory pathway, 030304 developmental biology, Biochemical networks, Prevention, Proteins, Reproducibility of Results, General Chemistry, 030104 developmental biology, Secretory protein, lcsh:Q, Generic health relevance, Metabolic engineering