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1
المؤلفون: Shuo-Bin Chen, Jie-Bin Ou, Jia-Heng Tan, Ding Li, Zhi-Shu Huang, Tian-Miao Ou, Liu-Lan Shen, Lian-Quan Gu, Shi-Liang Huang, Zhi-Hong Huang, Wei-Bin Wu
المصدر: European Journal of Medicinal Chemistry. 46:3339-3347
مصطلحات موضوعية: Lung Neoplasms, Cell Survival, Topoisomerase Inhibitors, medicine.drug_class, Stereochemistry, Adenocarcinoma of Lung, Antineoplastic Agents, Adenocarcinoma, Topoisomerase-I Inhibitor, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Antigens, Neoplasm, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, Telomerase, Etoposide, Pyrans, Pharmacology, Nasopharyngeal Carcinoma, biology, Topoisomerase, Carcinoma, Organic Chemistry, Quinones, Nasopharyngeal Neoplasms, DNA, General Medicine, DNA-Binding Proteins, DNA Topoisomerases, Type II, DNA Topoisomerases, Type I, chemistry, Biochemistry, Enzyme inhibitor, Pyran, biology.protein, Drug Screening Assays, Antitumor, Sesquiterpenes, Topoisomerase inhibitor, Naphthoquinones, Plasmids, medicine.drug
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2
المؤلفون: Lin-Kun An, Tian-Miao Ou, Zhi-Shu Huang, Lian-Quan Gu, Ming-Hao Hu, Pei-Fen Yao, Jia-Heng Tan, Shi-Tian Zhuo, Shi-Liang Huang, Chun-Yan Li, Shuo-Bin Chen, Ding Li
المصدر: Organicbiomolecular chemistry. 11(24)
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Stereochemistry, Phenazine, Antineoplastic Agents, Apoptosis, HL-60 Cells, Cleavage (embryo), Biochemistry, HeLa, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, medicine, Structure–activity relationship, Humans, Topoisomerase II Inhibitors, Physical and Theoretical Chemistry, Cell Proliferation, biology, Dose-Response Relationship, Drug, Topoisomerase, Organic Chemistry, DNA replication, biology.organism_classification, Recombinant Proteins, DNA Topoisomerases, Type II, chemistry, DNA Topoisomerases, Type I, biology.protein, MCF-7 Cells, Phenazines, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, DNA, Topoisomerase inhibitor, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1ea4d3ee3dca468b99c9c43e09e638
https://pubmed.ncbi.nlm.nih.gov/23657605 -
3ChemInform Abstract: Synthesis and Evaluation of Mansonone F Derivatives as Topoisomerase Inhibitors
المؤلفون: Shi-Liang Huang, et al. et al.
المصدر: ChemInform. 42
مصطلحات موضوعية: Terpene, medicine.drug_class, Stereochemistry, Chemistry, Mansonone F, medicine, General Medicine, Topoisomerase inhibitor
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المؤلفون: Bin Wang, Ding Li, Yue Li, Lian-Quan Gu, Yi-Chi Mai, Zhi-Shu Huang, Jin-Qiang Hou, Jia-Heng Tan, Tian-Miao Ou, Lin-Kun An, Shi-Liang Huang
المصدر: European journal of medicinal chemistry. 45(4)
مصطلحات موضوعية: Models, Molecular, Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Tertiary amine, Stereochemistry, medicine.drug_class, Drug Evaluation, Preclinical, Carboxamide, Chemical synthesis, Indole Alkaloids, chemistry.chemical_compound, Structure-Activity Relationship, Alkaloids, Drug Discovery, medicine, Structure–activity relationship, Pharmacology, biology, Alkaloid, Organic Chemistry, General Medicine, Rutaecarpine, Acetylcholinesterase, chemistry, Enzyme inhibitor, biology.protein, Quinazolines, Cholinesterase Inhibitors
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المؤلفون: Yong-Biao Wei, Lian-Quan Gu, Lin Ma, Wei Qiao, Chi Zhang, Huang Tang, Shi-Liang Huang, Zhi-Shu Huang, Fang-Xian Ning
المصدر: European journal of medicinal chemistry. 44(6)
مصطلحات موضوعية: Models, Molecular, Aporphines, medicine.drug_class, Stereochemistry, Drug Evaluation, Preclinical, Carboxamide, Crystallography, X-Ray, Torpedo, Chemical synthesis, chemistry.chemical_compound, Alkaloids, Drug Discovery, medicine, Animals, Computer Simulation, Methiodide, Enzyme Inhibitors, Butyrylcholinesterase, Pharmacology, biology, Molecular Structure, Alkaloid, Organic Chemistry, Quinoline, Reproducibility of Results, Stereoisomerism, General Medicine, Acetylcholinesterase, chemistry, Models, Chemical, Enzyme inhibitor, Drug Design, biology.protein
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6Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors
المؤلفون: Yong-Biao Wei, Fang-Xian Ning, Zhi-Shu Huang, Lian-Quan Gu, Huang Tang, Albert S. C. Chan, Shi-Liang Huang
المصدر: Bioorganicmedicinal chemistry letters. 17(13)
مصطلحات موضوعية: Tertiary amine, medicine.drug_class, Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Crystallography, X-Ray, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Alkaloids, Cations, Drug Discovery, medicine, Methiodide, Enzyme Inhibitors, Protein Structure, Quaternary, Molecular Biology, Butyrylcholinesterase, biology, Alkaloid, Organic Chemistry, Acetylcholinesterase, chemistry, Models, Chemical, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Carbamates, Cholinesterase Inhibitors
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7
المؤلفون: Albert S. C. Chan, Xiaodong Wang, Lian Quan Gu, Shi-Liang Huang, Jianyong Wu, Yong Biao Wei, Jia Heng Tan, Huang Tang, Zhi Shu Huang, Lin Kun An
المصدر: European journal of medicinal chemistry. 43(5)
مصطلحات موضوعية: Aporphines, Stereochemistry, medicine.drug_class, Carboxamide, Antineoplastic Agents, Chemical synthesis, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Ethanolamine, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Methylene, Cytotoxicity, Pharmacology, Organic Chemistry, General Medicine, DNA, chemistry, Piperidine, Drug Screening Assays, Antitumor