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المؤلفون: Florence Gattacceca, Alexandre Evrard, Marc Ychou, Laure Deyme, Dominique Barbolosi, Nicole Tubiana-Mathieu, Litaty Mbatchi
المساهمون: Méthodes computationnelles pour la prise en charge thérapeutique en oncologie : Optimisation des stratégies par modélisation mécaniste et statistique (COMPO), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Universitaire Carémeau [Nîmes] (CHU Nîmes), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), CHU Limoges, Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), GATTACCECA, Florence
المصدر: Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology, 2021, 88 (2), pp.247-258. ⟨10.1007/s00280-021-04255-9⟩
Cancer Chemotherapy and Pharmacology, Springer Verlag, 2021, 88 (2), pp.247-258. ⟨10.1007/s00280-021-04255-9⟩مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, FOLFIRINOX, Leucovorin, Toxicology, 0302 clinical medicine, CPT-11, Antineoplastic Combined Chemotherapy Protocols, Pharmacology (medical), Population pharmacokinetics, ComputingMilieux_MISCELLANEOUS, education.field_of_study, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Oxaliplatin, 030220 oncology & carcinogenesis, FOLFIRI, Female, Fluorouracil, Folfirinox Regimen, Colorectal Neoplasms, medicine.drug, medicine.medical_specialty, Population, [SDV.CAN]Life Sciences [q-bio]/Cancer, Context (language use), Irinotecan, Nonlinear mixed effect modelling, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, Pharmacokinetics, Internal medicine, medicine, Humans, education, Pharmacology, business.industry, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, stomatognathic diseases, 030104 developmental biology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Camptothecin, Topoisomerase I Inhibitors, business
وصف الملف: application/pdf
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المؤلفون: Bong Seog Kim, Heung Tae Kim, Sang We Kim, Joo Hang Kim, Joung Soon Jang, Dong Wan Kim, Ki Hyeong Lee, Jin-Soo Kim, Ho Jung An, Jin Hyoung Kang, Hye Ryun Kim, Jin-Hyuk Choi
المصدر: British Journal of Cancer
مصطلحات موضوعية: Male, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Article, Small-cell lung cancer, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, medicine, Clinical endpoint, Humans, Infusions, Intravenous, Lung cancer, Aged, business.industry, Middle Aged, Prognosis, medicine.disease, Small Cell Lung Carcinoma, Clinical trial, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Camptothecin, Female, Topotecan, Neoplasm Recurrence, Local, Topoisomerase I Inhibitors, business, medicine.drug
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المؤلفون: Xiang Lin Yuan, Kei Muro, Satoshi Morita, Masahito Kotaka, Keun Wook Lee, Joong Bae Ahn, Sang-Hee Cho, Young Suk Park, Dong Sheng Zhang, Tomohiro Nishina, Wei Jia Fang, Ying Yuan, Hiroshi Matsuoka, Masato Nakamura, Satoru Iwasa, Li Bai, Yong Sang Hong, Junichi Sakamoto, Sae-Won Han, Tae Won Kim, Yasuhide Yamada
المصدر: Cancer Science
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Bevacizumab, Genotype, Colorectal cancer, Leucovorin, colorectal cancer, Gastroenterology, Deoxycytidine, Capecitabine, Young Adult, Clinical Research, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Confidence Intervals, Humans, Glucuronosyltransferase, XELIRI, irinotecan, Aged, Aged, 80 and over, business.industry, capecitabine, Hazard ratio, General Medicine, Original Articles, Middle Aged, medicine.disease, Prognosis, Progression-Free Survival, Irinotecan, Treatment Outcome, Oncology, Fluorouracil, FOLFIRI, Camptothecin, Female, Original Article, UGT1A1, Topoisomerase I Inhibitors, business, Colorectal Neoplasms, medicine.drug
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المؤلفون: Susan J. Keam
المصدر: Drugs. 80(5)
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Immunoconjugates, Colorectal cancer, Antineoplastic Agents, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, Breast cancer, Trastuzumab, Internal medicine, Neoplasms, medicine, Humans, Pharmacology (medical), skin and connective tissue diseases, neoplasms, Drug Approval, Adult patients, business.industry, Cancer, medicine.disease, DNA Topoisomerases, Type I, 030220 oncology & carcinogenesis, Accelerated approval, Camptothecin, Non small cell, Topoisomerase I Inhibitors, business, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Marin Mitsui, Yasushi Kirino, Keijo Fukushima, Masayuki Chuma, Hiroaki Yanagawa, Toshiaki Tamaki, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Takahiro Nimura, Hirofumi Hamano, Kenshi Takechi, Yoshito Zamami, Masaki Imanishi, Kazuhiko Teraoka, Yuya Horinouchi, Hiromichi Fujino, Naoto Okada, Toshimi Nakamura, Yasumasa Ikeda
المصدر: Supportive Care in Cancer. 27:849-856
مصطلحات موضوعية: Adult, Diarrhea, Male, Drug, Cholagogues and Choleretics, medicine.medical_specialty, Neutropenia, media_common.quotation_subject, Uterine Cervical Neoplasms, SN-38, Buffers, Irinotecan, Gastroenterology, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Active metabolite, Aged, Retrospective Studies, media_common, business.industry, Ursodeoxycholic Acid, Odds ratio, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Intestines, stomatognathic diseases, Sodium Bicarbonate, Oncology, chemistry, 030220 oncology & carcinogenesis, Uterine Neoplasms, Camptothecin, Female, Antacids, Topoisomerase I Inhibitors, Magnesium Oxide, business, Ovarian cancer, medicine.drug
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المؤلفون: Allyson J. Ocean, David M. Goldenberg, Pius Maliakal, Michael J. Guarino, William A. Wegener, Kevin Kalinsky, Alexander Starodub, D. Ross Camidge, Jamal Misleh, Wells A. Messersmith, Boyd Mudenda, Robert M. Sharkey, Jhanelle E. Gray, Ebenezer A. Kio, Leena Gandhi, Tirrell Johnson, Gregory A. Masters, Bryan J. Schneider, Rebecca S. Heist, Charles J. Schneider, Ronald J. Scheff, W. Thomas Purcell, Serengulam V. Govindan
المصدر: Clinical Cancer Research. 23:5711-5719
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Immunoconjugates, Drug-Related Side Effects and Adverse Reactions, Combination therapy, medicine.medical_treatment, Population, Kaplan-Meier Estimate, Neutropenia, Antibodies, Monoclonal, Humanized, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Antigens, Neoplasm, Internal medicine, Humans, Medicine, Molecular Targeted Therapy, education, Adverse effect, Aged, Aged, 80 and over, education.field_of_study, Chemotherapy, business.industry, Cancer, Middle Aged, medicine.disease, Small Cell Lung Carcinoma, Surgery, 030104 developmental biology, DNA Topoisomerases, Type I, 030220 oncology & carcinogenesis, Sacituzumab govitecan, Camptothecin, Female, Topotecan, Topoisomerase I Inhibitors, business, Cell Adhesion Molecules, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3588f6c198004cae5f52ab2059f6c0
https://doi.org/10.1158/1078-0432.ccr-17-0933 -
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المؤلفون: V Solfrini, E. De Mattia, Erika Cecchin, Rossana Roncato, Giuseppe Toffoli, Federico Innocenti, Angela Buonadonna, Luciana Giodini, Marcella Montico
المصدر: Clinical Pharmacology & Therapeutics. 102:123-130
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Pharmacogenomic Variants, Colorectal cancer, Cost-Benefit Analysis, Leucovorin, colorectal cancer, direct medical costs, Irinotecan, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Genotype, medicine, Humans, Pharmacology (medical), UGT1A1*28, Glucuronosyltransferase, Italy, cost of toxicity management, irinotecan, pharmacogenetics, Retrospective Studies, Neoplasm Staging, Pharmacology, business.industry, Retrospective cohort study, Middle Aged, Camptothecin, Female, Fluorouracil, Patient Care Management, Topoisomerase I Inhibitors, Colorectal Neoplasms, Pharmacogenomic Testing, medicine.disease, Confidence interval, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Toxicity, FOLFIRI, business, medicine.drug
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المؤلفون: Fengqin Gao, Zhensheng Liu, Peng Han, Hongliang Liu, Kristina R. Dahlstrom, Guojun Li, Kouros Owzar, Qingyi Wei, Erich M. Sturgis, Jose P. Zevallos
المصدر: European Journal of Cancer. 72:166-176
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, Pathology, medicine.medical_specialty, Alcohol Drinking, Apoptosis, Article, Tobacco smoke, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Odds Ratio, medicine, Humans, Lymphocytes, Aged, Polymorphism, Genetic, medicine.diagnostic_test, Squamous Cell Carcinoma of Head and Neck, business.industry, Smoking, Head and neck cancer, Cancer, Odds ratio, Middle Aged, Flow Cytometry, medicine.disease, stomatognathic diseases, 030104 developmental biology, Head and Neck Neoplasms, Case-Control Studies, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Biomarker (medicine), Camptothecin, Female, Topoisomerase I Inhibitors, business, medicine.drug
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المؤلفون: Arnulfo Mendoza, Christine M. Heske, Joshua T. Baumgart, Len Neckers, David A. Proia, Leah D. Edessa, Jane B. Trepel, Sunmin Lee, Lee J. Helman
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Oncology, Pathology, sarcoma, Drug Evaluation, Preclinical, Mice, SCID, Hsp90 inhibitor, chemistry.chemical_compound, Mice, 0302 clinical medicine, Rhabdomyosarcoma, Recurrent Ewing Sarcoma, drug conjugate, Child, Mice, Knockout, biology, Tumor Burden, 030220 oncology & carcinogenesis, Female, Sarcoma, medicine.drug, Research Paper, medicine.medical_specialty, SN-38, Antineoplastic Agents, Sarcoma, Ewing, Irinotecan, 03 medical and health sciences, topoisomerase 1 inhibitor, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, HSP90 Heat-Shock Proteins, neoplasms, business.industry, Topoisomerase, Cancer, Resorcinols, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, pediatric, chemistry, biology.protein, Camptothecin, Topoisomerase I Inhibitors, business, DNA Damage
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4d468d10ccd499403a16f2286b6461
http://europepmc.org/articles/PMC5323173 -
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المؤلفون: Kristen M. Weishaar, Melissa Paoloni, Heather Wilson-Robles, Michael O. Childress, Christina Mazcko, Jenna H Burton, Yves Pommier, Michael S. Kent, Nicole Northup, Erika Krick, Joseph E. Tomaszewski, James H. Doroshow, Jiuping Ji, Timothy M. Fan, Cheryl A. London, Lisa G. Barber, William C. Kisseberth, David M. Vail, Robert J. Kinders, Jan H Beumer, Ralph E. Parchment, Chand Khanna, Miguel Muzzio, Amy K. LeBlanc, EJ Ehrhart, Julie Eiseman, Susan E. Lana, Joseph M. Covey, Julianne L. Holleran, Jeffrey N. Bryan, Kelvin Y Kow
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 24, iss 23
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Lymphoma, Type I, Drug resistance, 0302 clinical medicine, Bone Marrow, Molecular Targeted Therapy, Cancer, Clinical Trials as Topic, biology, Hematology, DNA Topoisomerases, Type I, Tolerability, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Drug Monitoring, Development of treatments and therapeutic interventions, medicine.drug, medicine.medical_specialty, Maximum Tolerated Dose, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Antineoplastic Agents, Article, 03 medical and health sciences, Dogs, Rare Diseases, Pharmacokinetics, Clinical Research, Internal medicine, medicine, Animals, Oncology & Carcinogenesis, business.industry, Animal, Topoisomerase, Irinotecan, Disease Models, Animal, 030104 developmental biology, Orphan Drug, Good Health and Well Being, Pharmacodynamics, Disease Models, biology.protein, Topotecan, Topoisomerase I Inhibitors, business, Camptothecin, DNA Topoisomerases
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195f890eef28379dc62ccbdeaccf96cb
https://escholarship.org/uc/item/2zt0643k