يعرض 1 - 10 نتائج من 184 نتيجة بحث عن '"Ignacio I. Wistuba"', وقت الاستعلام: 1.52s تنقيح النتائج
  1. 1
    Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer

    المؤلفون: Hoa H.N. Pham, Junya Fukuoka, Qi Wang, Xingzhi Song, Ming Chen, Lauren Averett Byers, Lixia Diao, Won-Chul Lee, Yanhua Tian, Julie George, Shawna M Hubert, Bo Zhu, Xiao Hu, Ying Jin, Nicholas McGranahan, Chang-Jiun Wu, J. Jack Lee, Jing Wang, Carmen Behrens, Jianjun Zhang, Alexandre Reuben, Xin Hu, Jun Li, Roman K. Thomas, Latasha Little, Ignacio I. Wistuba, Junya Fujimoto, Jia Wu, Jiexin Zhang, Edwin R. Parra, Xiuning Le, John V. Heymach, Curtis Gumbs, Robert J. Cardnell, Bonnie S. Glisson, Meijuan Wu, Yamei Chen, Chao Cheng, William N. William, Don L. Gibbons, Runzhe Chen, Chi-Wan Chow, P. Andrew Futreal, Jianhua Zhang

    المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
    Nature Communications

    مصطلحات موضوعية: Adult, Male, Lung Neoplasms, DNA Copy Number Variations, T-Lymphocytes, Tumour heterogeneity, medicine.medical_treatment, Science, Cell, Receptors, Antigen, T-Cell, Loss of Heterozygosity, General Physics and Astronomy, Biology, Article, Small-cell lung cancer, General Biochemistry, Genetics and Molecular Biology, Genetic Heterogeneity, Interferon-gamma, HLA Antigens, Carcinoma, Non-Small-Cell Lung, Exome Sequencing, Cancer genomics, medicine, Humans, Lung cancer, Gene, Exome, neoplasms, Aged, Aged, 80 and over, Multidisciplinary, Lung, T-cell receptor, General Chemistry, Immunotherapy, Middle Aged, medicine.disease, Small Cell Lung Carcinoma, Survival Analysis, humanities, respiratory tract diseases, medicine.anatomical_structure, Mutation, Cancer research, Tumour immunology, Immunohistochemistry, Female, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47ab032b2da820c84c354b68abd98c7
    https://doaj.org/article/61c0fcf9baf94acab6feccd225cfafb0

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  2. 2
    Evaluation of Pathologic Response in Lymph Nodes of Patients With Lung Cancer Receiving Neoadjuvant Chemotherapy

    المؤلفون: Stephen G. Swisher, Boris Sepesi, John V. Heymach, Ignacio I. Wistuba, Apar Pataer, Tina Cascone, Arlene M. Correa, Annikka Weissferdt, Ara A. Vaporciyan

    المصدر: Journal of Thoracic Oncology. 16:1289-1297

    مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, 03 medical and health sciences, 0302 clinical medicine, Major Pathologic Response, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pathologic Response, Lung cancer, Retrospective Studies, Chemotherapy, business.industry, Proportional hazards model, Surrogate endpoint, Prognosis, medicine.disease, Primary tumor, Neoadjuvant Therapy, 030104 developmental biology, 030220 oncology & carcinogenesis, Lymph Nodes, Lymph, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0945fccbf730c40512826ff288b2816f
    https://doi.org/10.1016/j.jtho.2021.03.029

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  3. 3
    Immune Phenotype and Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer

    المؤلفون: Anne V. Philips, Jason B White, Jennifer A. Wargo, Sahil Seth, Xiangjie Sun, Senthil Damodaran, Andrew Futreal, Gabriel N. Hortobagyi, Er-Yen Yen, Clinton Yam, Baohua Sun, Gheath Alatrash, Stacy L. Moulder, Qingqing Ding, Edwin Roger Parra Cuentas, Ignacio I. Wistuba, Fei Yang, Elizabeth A. Mittendorf, Jeffrey T. Chang, Elizabeth Ravenberg, Haven R. Garber, Jennifer L. Guerriero, Bora Lim, Jennifer K. Litton, Ryan Sun, Lei Huo, Kasthuri Kannan, Naoto T. Ueno, Roland L. Bassett, Gaiane M. Rauch, William Fraser Symmans

    المصدر: Clin Cancer Res

    مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, CD3, Triple Negative Breast Neoplasms, Article, B7-H1 Antigen, Lymphocytes, Tumor-Infiltrating, Immune system, Breast cancer, Internal medicine, Tumor Microenvironment, medicine, Humans, Neoadjuvant therapy, Triple-negative breast cancer, biology, business.industry, Odds ratio, Prognosis, medicine.disease, Neoadjuvant Therapy, Phenotype, Nat, biology.protein, Immunohistochemistry, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d514d3ca018b4a1893424f007cf22d
    https://doi.org/10.1158/1078-0432.ccr-21-0144

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  4. 4
    Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma

    المؤلفون: John V. Heymach, Barbara Mino, J. Jack Lee, Pedro Rocha, Cesar A. Moran, David C. Rice, Edwin R. Parra, Humam Kadara, Boris Sepesi, Lei Feng, Luisa M. Solis, Carmen Behrens, Ignacio I. Wistuba, Don L. Gibbons, Jianjun Zhang, Chad J. Creighton, Jaime Rodriguez-Canales

    المصدر: Clinical Lung Cancer. 22:e415-e424

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Adenocarcinoma of Lung, Gene mutation, Logistic regression, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Germline mutation, Immune system, AMP-Activated Protein Kinase Kinases, Internal medicine, medicine, Humans, Lung cancer, Immune Checkpoint Inhibitors, Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, business.industry, Immunotherapy, Middle Aged, medicine.disease, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Adenocarcinoma, Female, business, CD8

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14df1fdefb5222e9d44b3cb558cfa4fc
    https://doi.org/10.1016/j.cllc.2020.06.003

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  5. 5
    Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features

    المؤلفون: Runzhe Chen, Boris Sepesi, Jie Ye, J. Jack Lee, John V. Heymach, Junya Fujimoto, Baili Zhang, Nicholas McGranahan, Jianhua Zhang, Latasha Little, Junya Fukuoka, Harvey I. Pass, Dzifa Y. Duose, Chi Wan Chow, Hitoshi Dejima, Kazuhiro Tabata, Humam Kadara, Alexandre Reuben, Marcos R. Estecio, Jiexin Zhang, Xin Hu, Ara A. Vaporciyan, Jia Wu, Lisha Ying, Curtis Gumbs, Hoa H.N. Pham, Paul Scheet, Myrna C.B. Godoy, Carmen Behrens, Cara Haymaker, P. Andrew Futreal, Dan Su, Jianjun Zhang, Luisa M. Solis, Shawna M Hubert, Edwin R. Parra, Ignacio I. Wistuba, Mara B. Antonoff

    المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

    مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Carcinogenesis, medicine.medical_treatment, General Physics and Astronomy, medicine.disease_cause, T-Lymphocytes, Regulatory, 0302 clinical medicine, Tumor Microenvironment, Cytotoxic T cell, Lung, Multidisciplinary, Immunosuppression, T-Lymphocytes, Helper-Inducer, respiratory system, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Adenocarcinoma, Signal Transduction, DNA Copy Number Variations, T cell, Science, chemical and pharmacologic phenomena, Adenocarcinoma of Lung, Adenocarcinoma in Situ, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, medicine, Humans, Chromosome Aberrations, Gene Expression Profiling, T-cell receptor, General Chemistry, DNA Methylation, medicine.disease, Immunity, Innate, Clone Cells, body regions, 030104 developmental biology, Immunoediting, Cancer research, Tumor Escape, Transcriptome, Precancerous Conditions, T-Lymphocytes, Cytotoxic

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dca5820eeda487e4d0fa64c1cad20e
    https://doaj.org/article/90f6cd0b92e742178a0fc4cce008b8e0

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  6. 6
    Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial

    المؤلفون: Cheuk Hong Leung, Wayne L. Hofstetter, John V. Heymach, Alexandre Reuben, Myrna C.B. Godoy, Ara A. Vaporciyan, Padmanee Sharma, Yasir Elamin, Neda Kalhor, Robert R. Jenq, Junya Fujimoto, Tina Cascone, Anne S. Tsao, William N. William, Charles Lu, Frank E. Mott, Nadim J. Ajami, Don L. Gibbons, Jack A. Roth, David C. Rice, Luisa M. Solis, Hai T. Tran, Brett W. Carter, Lauren Averett Byers, Andrew Futreal, Lorenzo Federico, Annikka Weissferdt, Garrett L. Walsh, Reza J. Mehran, Chantale Bernatchez, George R. Blumenschein, Jennifer A. Wargo, Heather Lin, Cara Haymaker, Xiuning Le, Jonathan M. Kurie, Mehmet Altan, James P. Allison, Stephen G. Swisher, Edwin R. Parra, Boris Sepesi, Hitoshi Dejima, Frank V. Fossella, Jianjun Zhang, Bonnie S. Glisson, Mara B. Antonoff, Abdul Wadud Khan, Apar Pataer, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Humam Kadara, J. Jack Lee, Ferdinandos Skoulidis

    المصدر: Nat Med

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Ipilimumab, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Clinical endpoint, Carcinoma, Humans, Medicine, Lung cancer, Neoadjuvant therapy, Aged, Chemotherapy, business.industry, General Medicine, Middle Aged, medicine.disease, Neoadjuvant Therapy, Clinical trial, Nivolumab, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, business, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397765979e94f0ae175dc106bcb84916
    https://doi.org/10.1038/s41591-020-01224-2

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  7. 7
    CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma

    المؤلفون: Pedro Rocha, Dzifa Y. Douse, Lixia Diao, Humam Kadara, Jianjun Zhang, Debora A. Ledesma, Jose Luis Solorzano, John V. Heymach, Ruth Salazar, Luisa M. Solis, Neda Kalhor, Barbara Mino, J. Jack Lee, Don L. Gibbons, Cesar A. Moran, David C. Rice, Carmen Behrens, Pamela Villalobos, Ara A. Vaporciyan, Jiexin Zhang, Hitoshi Dejima, Annikka Weissferdt, Kyle G. Mitchell, Tina Cascone, Edwin Parra-Cuentas, Boris Sepesi, Xiuning Le, Ignacio I. Wistuba

    المصدر: Cancer Immunology, Immunotherapy

    مصطلحات موضوعية: Male, Lung adenocarcinoma, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Immune profiling, Atypical hyperplasia, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Immunology and Allergy, 5'-Nucleotidase, Neoadjuvant therapy, Aged, 80 and over, 0303 health sciences, biology, Immunosuppression, Middle Aged, Prognosis, Oncology, 030220 oncology & carcinogenesis, Adenocarcinoma, Immunohistochemistry, Female, Original Article, medicine.symptom, Adult, PD-L1, Immunology, Adenocarcinoma of Lung, Inflammation, GPI-Linked Proteins, 03 medical and health sciences, Immune system, Biomarkers, Tumor, medicine, Humans, Immunologic Factors, Aged, Retrospective Studies, 030304 developmental biology, business.industry, Correction, medicine.disease, Adenosinergic pathway, CD73, Cancer research, biology.protein, business, Follow-Up Studies

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbd70305f4bb43f38d0b30944fff54a
    https://doi.org/10.1007/s00262-020-02820-4

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  8. 8
    Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC

    المؤلفون: Erin M. Corsini, Junya Fujimoto, Humam Kadara, Ara A. Vaporciyan, Qi Wang, Jing Wang, Ignacio I. Wistuba, Carmen Behrens, Alexandre Reuben, Stephen G. Swisher, Pierre Olivier Gaudreau, Garrett L. Walsh, Lorenzo Federico, Cara Haymaker, Curtis Gumbs, Emily Roarty, Lixia Diao, Jun Li, Edwin Parra-Cuentas, P. Andrew Futreal, Tatiana Karpinets, John V. Heymach, Hai T. Tran, Boris Sepesi, Daniel J. McGrail, Jianhua Zhang, Kyle G. Mitchell, Annikka Weissferdt, Daniel R. Gomez, Don L. Gibbons, Marcelo V. Negrao, Mara B. Antonoff, Chantale Bernatchez, Latasha Little, Roohussaba Khairullah, Tina Cascone, Jianjun Zhang, Arlene M. Correa

    المصدر: J Thorac Oncol

    مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Lung Neoplasms, medicine.medical_treatment, CD8-Positive T-Lymphocytes, Article, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, parasitic diseases, Tumor Microenvironment, medicine, Humans, Cytotoxic T cell, B cell, CD20, B-Lymphocytes, Chemotherapy, biology, medicine.diagnostic_test, business.industry, Neoadjuvant Therapy, Immune checkpoint, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, business, Immunologic Memory, Memory T cell, CD8

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e065792a3ebc80c4c707b4de000b1e1
    https://doi.org/10.1016/j.jtho.2020.09.027

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  9. 9
    Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

    المؤلفون: Chang-Jiun Wu, Ximing Tang, David H. Peng, Marcelo V. Negrao, Aik Choon Tan, Kazutaka Fukumura, Stephen G. Swisher, John V. Heymach, Jing Wang, Xin Hu, Latasha Little, Alexandre Reuben, Jianhua Zhang, Anthony San Lucas, Kenichi Suda, Jianjun Zhang, Ali Jalali, P. Andrew Futreal, Won-Chul Lee, Shawna M Hubert, Emily Roarty, Marcus Coyle, Erik P. Sulman, Ganesh Rao, Carmen Behrens, Jason T. Huse, Rebecca Thornton, Neda Kalhor, Jihye Kim, Xingzhi Song, Don L. Gibbons, Runzhe Chen, Whijae Roh, Chia Chin Wu, Chi-Wan Chow, Daniel R. Gomez, Lixia Diao, Chad Tang, Wei Lu, Jun Li, Curtis Gumbs, Nicholas McGranahan, Junya Fujimoto, J. Jack Lee, Paul Scheet, Ignacio I. Wistuba

    المصدر: Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
    Genome Biology

    مصطلحات موضوعية: Lung Neoplasms, lcsh:QH426-470, Somatic cell, medicine.medical_treatment, Biology, Immune profiling, Metastasis, Transcriptome, Mice, Carcinoma, Non-Small-Cell Lung, Exome Sequencing, medicine, Animals, Humans, Neoplasm Metastasis, Lung cancer, lcsh:QH301-705.5, Exome sequencing, Immunosuppression Therapy, Research, Immunosuppression, Genomics, DNA Methylation, medicine.disease, Multiomics, Immunohistochemistry, Gene Expression Regulation, Neoplastic, Disease Models, Animal, lcsh:Genetics, lcsh:Biology (General), Mutation, Monoclonal, Cancer research, Gene expression, DNA methylation

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d59adc61a695b496bd3d81f1bc64c0
    http://link.springer.com/article/10.1186/s13059-020-02175-0

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  10. 10
    The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker

    المؤلفون: John W. Longshore, Jin Haeng Chung, Gang Chen, Yuko Minami, Anja C. Roden, Ignacio I. Wistuba, Johan Botling, Teh Ying Chou, Erik Thunnissen, Elisabeth Brambilla, Fred R. Hirsch, Jillian B. Daigneault, Solange Peters, Sanja Dacic, Natasha Rekhtman, Ahmet Zehir, William D. Travis, Lukas Bubendorf, Mary Beth Beasley, Andrew G. Nicholson, Sylvie Lantuejoul, Alain C. Borczuk, Wendy A Cooper, Ming-Sound Tsao, Dongmei Lin, Yasushi Yatabe, Masayuki Noguchi, Fernando López-Ríos, Keith M. Kerr, Mari Mino-Kenudson, Mauro Papotti, David M. Hwang, Deepali Jain, Akihiko Yoshida, Andre L. Moreira, Lynette M. Sholl, Giuseppe Pelosi, Claudia Poleri

    المصدر: Sholl, L M, Hirsch, F R, Hwang, D, Botling, J, Lopez-Rios, F, Bubendorf, L, Mino-Kenudson, M, Roden, A C, Beasley, M B, Borczuk, A, Brambilla, E, Chen, G, Chou, T Y, Chung, J H, Cooper, W A, Dacic, S, Lantuejoul, S, Jain, D, Lin, D, Minami, Y, Moreira, A, Nicholson, A G, Noguchi, M, Papotti, M, Pelosi, G, Poleri, C, Rekhtman, N, Tsao, M S, Thunnissen, E, Travis, W, Yatabe, Y, Yoshida, A, Daigneault, J B, Zehir, A, Peters, S, Wistuba, I I, Kerr, K M & Longshore, J W 2020, ' The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker : A Perspective from the International Association for the Study of Lung Cancer Pathology Committee ', Journal of Thoracic Oncology, vol. 15, no. 9, pp. 1409-1424 . https://doi.org/10.1016/j.jtho.2020.05.019
    J Thorac Oncol

    مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, medicine.disease_cause, Article, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, PD-L1, medicine, Humans, Lung cancer, Adverse effect, Retrospective Studies, Mutation, biology, business.industry, Immunotherapy, medicine.disease, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Biomarker (medicine), Fatal disease, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233716e7b81aeeb45e8e025c5c02bcb0
    https://doi.org/10.1016/j.jtho.2020.05.019

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