المؤلفون: Zhou X; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Nicholson AM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Ren Y; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA., Brooks M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Jiang P; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Zuberi A; The Rare and Orphan Disease Center, JAX Center for Precision Genetics, 600 Main Street, Bar Harbor, ME, 04609, USA., Phuoc HN; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Perkerson RB; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Matchett B; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Parsons TM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Finch NA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Lin W; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Qiao W; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Castanedes-Casey M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Phillips V; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Librero AL; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Asmann Y; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA., Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Lutz C; The Rare and Orphan Disease Center, JAX Center for Precision Genetics, 600 Main Street, Bar Harbor, ME, 04609, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA., Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.; VIB Center for Molecular Neurology, Universiteitsplein 1, 2610, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium.

المصدر: Brain : a journal of neurology [Brain] 2020 Jun 01; Vol. 143 (6), pp. 1905-1919.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

مواضيع طبية MeSH: Frontotemporal Dementia/*genetics , Frontotemporal Dementia/*therapy , Membrane Proteins/*genetics , Nerve Tissue Proteins/*genetics, Animals ; DNA-Binding Proteins/metabolism ; Female ; Gene Expression/genetics ; Haplotypes ; HeLa Cells ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Male ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Mutation/genetics ; Nerve Fibers, Myelinated/pathology ; Nerve Tissue Proteins/metabolism ; Polymorphism, Single Nucleotide/genetics ; Transcriptome/genetics

المؤلفون: Nicholson AM; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Zhou X; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Perkerson RB; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Parsons TM; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Chew J; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Brooks M; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., DeJesus-Hernandez M; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Finch NA; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Matchett BJ; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Kurti A; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Jansen-West KR; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Perkerson E; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Daughrity L; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Castanedes-Casey M; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Rousseau L; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Phillips V; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Hu F; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, 345 Weill Hall, Ithaca, NY, 14853, USA., Gendron TF; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Murray ME; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Dickson DW; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Fryer JD; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Rademakers R; Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. rademakers.rosa@mayo.edu.

المصدر: Acta neuropathologica communications [Acta Neuropathol Commun] 2018 May 31; Vol. 6 (1), pp. 42. Date of Electronic Publication: 2018 May 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE

مواضيع طبية MeSH: C9orf72 Protein/*genetics , DNA Repeat Expansion/*genetics , Frontotemporal Lobar Degeneration/*genetics , Frontotemporal Lobar Degeneration/*therapy , Gene Expression Regulation/*genetics , Membrane Proteins/*deficiency , Tumor Suppressor Proteins/*deficiency, Animals ; C9orf72 Protein/metabolism ; Cell Line, Transformed ; Conditioning, Psychological/physiology ; Disease Models, Animal ; Exploratory Behavior ; Fear/psychology ; Frontotemporal Lobar Degeneration/psychology ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Glycerophosphates ; Humans ; Interpersonal Relations ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Transduction, Genetic ; Tumor Suppressor Proteins/genetics

المؤلفون: Murray ME; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA., Cannon A, Graff-Radford NR, Liesinger AM, Rutherford NJ, Ross OA, Duara R, Carrasquillo MM, Rademakers R, Dickson DW

المصدر: Acta neuropathologica [Acta Neuropathol] 2014 Sep; Vol. 128 (3), pp. 411-21. Date of Electronic Publication: 2014 Jun 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/classification , Alzheimer Disease*/genetics , Alzheimer Disease*/pathology, Apolipoproteins E/*genetics , DNA-Binding Proteins/*genetics , Hippocampus/*pathology , Intercellular Signaling Peptides and Proteins/*genetics , Membrane Proteins/*genetics , Nerve Tissue Proteins/*genetics, Aged ; Aged, 80 and over ; Aging/genetics ; Aging/pathology ; Cognition Disorders/etiology ; Cognition Disorders/genetics ; DNA Mutational Analysis ; Female ; Humans ; Longitudinal Studies ; Male ; Neurofibrillary Tangles/pathology ; Neuropsychological Tests ; Plaque, Amyloid/pathology ; Progranulins ; Sclerosis/pathology ; Statistics, Nonparametric

المؤلفون: van Blitterswijk M; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA, VanBlitterswijk.Marka@mayo.edu., Mullen B, Nicholson AM, Bieniek KF, Heckman MG, Baker MC, DeJesus-Hernandez M, Finch NA, Brown PH, Murray ME, Hsiung GY, Stewart H, Karydas AM, Finger E, Kertesz A, Bigio EH, Weintraub S, Mesulam M, Hatanpaa KJ, White CL 3rd, Strong MJ, Beach TG, Wszolek ZK, Lippa C, Caselli R, Petrucelli L, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Mackenzie IR, Seeley WW, Grinberg LT, Miller BL, Boylan KB, Graff-Radford NR, Boeve BF, Dickson DW, Rademakers R

المصدر: Acta neuropathologica [Acta Neuropathol] 2014 Mar; Vol. 127 (3), pp. 397-406. Date of Electronic Publication: 2014 Jan 03.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Frontotemporal Dementia/*genetics , Membrane Proteins/*genetics , Nerve Tissue Proteins/*genetics , Proteins/*genetics, Adult ; Age of Onset ; Aged ; Aged, 80 and over ; Alleles ; C9orf72 Protein ; Cohort Studies ; DNA Repeat Expansion ; DNA-Binding Proteins/metabolism ; Female ; Frontotemporal Dementia/complications ; Frontotemporal Dementia/metabolism ; Genetic Predisposition to Disease ; Genotype ; Heterozygote ; Humans ; Male ; Middle Aged ; Models, Genetic ; Motor Neuron Disease/complications ; Motor Neuron Disease/genetics ; Motor Neuron Disease/metabolism ; Polymorphism, Single Nucleotide

المؤلفون: Gauger KJ; Pioneer Valley Life Sciences Institute, Baystate Medical Center, Springfield, MA 01199, USA. kelly.gauger@bhs.org, Chenausky KL, Murray ME, Schneider SS

المصدر: BMC cancer [BMC Cancer] 2011 Feb 08; Vol. 11, pp. 59. Date of Electronic Publication: 2011 Feb 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Intercellular Signaling Peptides and Proteins/*deficiency , Membrane Proteins/*deficiency , Transforming Growth Factor beta/*metabolism, Animals ; Down-Regulation ; Epithelial-Mesenchymal Transition ; Gene Knockdown Techniques ; Homeodomain Proteins/antagonists & inhibitors ; Homeodomain Proteins/biosynthesis ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Phosphorylation ; Pyrazoles/pharmacology ; Pyrroles/pharmacology ; Repressor Proteins/antagonists & inhibitors ; Repressor Proteins/biosynthesis ; Signal Transduction ; Telomerase/genetics ; Telomerase/metabolism ; Zinc Finger E-box Binding Homeobox 2