المؤلفون: Edlund, Sofia, Lee, So Young, Grimsby, Susanne, Zhang, Shouthing, Aspenström, Pontus, Heldin, Carl-Henrik, Landström, Maréne

المصدر: Molecular and Cellular Biology. 25(4):1475-1488

مصطلحات موضوعية: Animals, Apoptosis/drug effects/*physiology, COS Cells, Cell Fractionation, Cercopithecus aethiops, Cytoskeletal Proteins/*metabolism, DNA-Binding Proteins/*metabolism, Glycogen Synthase Kinase 3/metabolism, Humans, Male, Mice, Phosphorylation/drug effects, Prostatic Neoplasms/metabolism, Protein Binding/drug effects, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins/metabolism, RNA, Small Interfering/metabolism, Research Support, Non-U.S. Gov't, Serine/metabolism, Trans-Activators/*metabolism, Transcription Factors/*metabolism, Transforming Growth Factor beta/*pharmacology, Tumor Cells, Cultured, p38 Mitogen-Activated Protein Kinases/metabolism

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-72728
https://doi.org/10.1128/MCB.25.4.1475-1488.2005
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15684397&dopt=Citation

المؤلفون: Jang, Jessica C., Li, Jiang, Gambini, Luca, Batugedara, Hashini Maneesha, Sati, Sandeep, Lazar, Mitchell A., Fan, Li, Pellecchia, Maurizio, Nair, Meera G.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 114 (48), E10399-E10408 (2017)

مصطلحات موضوعية: Animals, Biological Therapy/methods, Disease Models, Animal, Female, Gram-Negative Bacteria/immunology/metabolism, Humans, Lipopolysaccharide Receptors/immunology/metabolism, Lipopolysaccharides/immunology/metabolism, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nippostrongylus/immunology, Protective Agents, Protein-Serine-Threonine Kinases/metabolism, Recombinant Proteins/administration & dosage/immunology/metabolism, Resistin/immunology, STAT3 Transcription Factor/metabolism, Shock, Septic/immunology/microbiology/therapy, Signal Transduction/immunology, Toll-Like Receptor 4/immunology/metabolism, LPS, TLR4, inflammation, resistin, sepsis, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:0027-8424; urn:issn:1091-6490

URL الوصول: https://orbi.uliege.be/handle/2268/235969

المؤلفون: Pierre, Nicolas, Fernandez-Verdejo, Rodrigo, Regnier, Pauline, Vanmechelen, Simon, Demeulder, Benedicte, Francaux, Marc

المصدر: Cell Biology International, 40 (1), 91-9 (2016)

مصطلحات موضوعية: Animals, Cell Cycle Proteins/metabolism, Cell Line, Endoplasmic Reticulum/metabolism, Endoplasmic Reticulum Stress/physiology, Endoribonucleases/metabolism, Insulin/metabolism, Insulin Resistance/physiology, JNK Mitogen-Activated Protein Kinases/metabolism, Membrane Proteins/metabolism, Mice, Muscle Fibers, Skeletal/drug effects/metabolism, Palmitates/pharmacology, Phosphorylation, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/drug effects, Stress, Physiological/physiology, Unfolded Protein Response, ER stress, JNK, UPR, insulin resistance, muscle, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:1065-6995; urn:issn:1095-8355

URL الوصول: https://orbi.uliege.be/handle/2268/222124

المؤلفون: Handoko, L., Kaczkowski, B., Hon, C. C., Lizio, M., Wakamori, M., Matsuda, T., Ito, T., Jeyamohan, P., Sato, Y., Sakamoto, K., Yokoyama, S., Kimura, Hiroshi, Minoda, A., Umehara, T.

المصدر: Epigenetics. 13(No. 4):410-431

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cage, Cancer Research, Lung Neoplasms, Histones, Mice, Lung Neoplasms/drug therapy/*genetics/metabolism, Carcinoma, Non-Small-Cell Lung, Transcriptional regulation, Histone code, Promoter Regions, Genetic, Azepines/*pharmacology, Triazoles/*pharmacology, Brd2, biology, Chemistry, Acetylation, Azepines, Chromatin, Cell biology, Jq1, Gene Expression Regulation, Neoplastic, Histone, Protein-Serine-Threonine Kinases/*metabolism, Transcription Initiation Site, Proto-Oncogene Proteins c-myc/genetics, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins c-myc, Histone H4, Chromatin/metabolism, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Enhancer, Molecular Biology, Transcription factor, Promoter Regions, Genetic/drug effects, Transcription Initiation Site/drug effects, Carcinoma, Non-Small-Cell Lung/drug therapy/*genetics/metabolism, Promoter, Triazoles, Acetylation/drug effects, Bromodomain, 030104 developmental biology, Histones/*chemistry/metabolism, Gene Expression Regulation, Neoplastic/drug effects, Bet, biology.protein, Cancer research, H4 hyperacetylation, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed72bd1e8abe48f7e395d18d2ff5bbd
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100822105

المؤلفون: Pierre, Nicolas, Barbe, Caroline, Gilson, Helene, Deldicque, Louise, Raymackers, Jean-Marc, Francaux, Marc

المصدر: Biochemical and Biophysical Research Communications, 450 (1), 459-63 (2014)

مصطلحات موضوعية: Animals, Cell Line, Endoplasmic Reticulum/drug effects/physiology, Endoribonucleases/metabolism, Hydrogen Peroxide/pharmacology, Mice, Muscle Fibers, Skeletal/drug effects/metabolism, Oxidative Stress/drug effects/physiology, Protein-Serine-Threonine Kinases/metabolism, Reactive Oxygen Species/metabolism, eIF-2 Kinase/metabolism, Activating transcription factor 6 (ATF6), Binding immunoglobulin protein (BiP), Eukaryotic translation-initiation factor 2alpha (eIF2alpha), Oxidative stress, Unfolded protein response (UPR), X-box binding protein 1 spliced (XBP1s), Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:0006-291X; urn:issn:1090-2104

URL الوصول: https://orbi.uliege.be/handle/2268/237033

المؤلفون: Victor A. Neel, Seung-Hee Jo, G. Paolo Dotto, Maria-Giuseppina Procopio, Sandro Goruppi, Andrea Clocchiatti

المصدر: Cell Reports, Vol 20, Iss 10, Pp 2468-2479 (2017)
Cell reports, vol. 20, no. 10, pp. 2468-2479

مصطلحات موضوعية: squamous cell carcinoma, 0301 basic medicine, autophagy, Stromal cell, cancer-associated fibroblast, Notch signaling pathway, Fluorescent Antibody Technique, Protein Serine-Threonine Kinases, Biology, Zinc Finger Protein GLI1, Article, General Biochemistry, Genetics and Molecular Biology, Mice, ULK3, 03 medical and health sciences, Cancer-Associated Fibroblasts, Downregulation and upregulation, GLI2, Animals, Humans, tumor microenvironment, Gene silencing, CAF, Autophagy/physiology, Cancer-Associated Fibroblasts/metabolism, Female, Fibroblasts/metabolism, Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism, Signal Transduction/genetics, Signal Transduction/physiology, Zinc Finger Protein GLI1/genetics, Zinc Finger Protein GLI1/metabolism, CSL/RBPJ, GLI, SCC, cancer stroma, lcsh:QH301-705.5, RBPJ, Autophagy, Fibroblasts, 030104 developmental biology, lcsh:Biology (General), Immunoglobulin J Recombination Signal Sequence-Binding Protein, Cancer research, Signal transduction, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4684324d12d6bb849ddff53b0ff07fed
https://doi.org/10.1016/j.celrep.2017.08.048

المؤلفون: Mouton, Veronique, Toussaint, Louise, Vertommen, Didier, Gueuning, Marie-Agnes, Maisin, Liliane, Havaux, Xavier, Sanchez-Canedo, Cossette, Bertrand, Luc, Dequiedt, Franck, Hemmings, Brian A, Hue, Louis, Rider, Mark H

المصدر: Biochemical Journal, 431 (2), 267-75 (2010)

مصطلحات موضوعية: Animals, Binding Sites, Cattle, Cell Line, Enzyme Activation/drug effects, Humans, Insulin/pharmacology, Male, Mice, Mice, Transgenic, Mutation/genetics, Myocardium/cytology/enzymology, Myocytes, Cardiac/drug effects/enzymology, Organ Specificity/drug effects, Phosphofructokinase-2/metabolism, Protein Kinase Inhibitors/pharmacology, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins c-akt/antagonists & inhibitors/deficiency/metabolism, Rats, Rats, Wistar, Substrate Specificity/drug effects, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:0264-6021; urn:issn:1470-8728

URL الوصول: https://orbi.uliege.be/handle/2268/78031

المؤلفون: Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, De Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, De Chaldée, Michel, Auregan, Gwenaëlle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Mérienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme, Déglon, Nicole, Brouillet, Emmanuel

المساهمون: Service MIRCEN (MIRCEN), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire des Maladies Neurodégénératives - UMR 9199 (LMN), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Institut d'Imagerie BioMédicale (I2BM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Biocortech, Service de Biologie Intégrative et Génétique Moléculaire (SBIGeM), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut des cellules souches pour le traitement et l'étude des maladies monogéniques (I-STEM), Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM), inconnu, Inconnu, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de neurosciences cognitives et adaptatives (LNCA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Hôpital Ophtalmique Jules-Gonin [Lausanne], Université de Lausanne (UNIL)-Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Fondation FondaMental [Créteil], Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Généthon-Université d'Évry-Val-d'Essonne (UEVE), Régulations cellulaires et oncogenèse (RCO), Institut Curie [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie du Développement de Marseille (IBDM), Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire [Grenoble] (CHU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Généthon, ANR-11-INBS-0011,NeurATRIS,Infrastructure de Recherche Translationnelle pour les Biothérapies en Neurosciences(2011), European Project: 222925,EC:FP7:HEALTH,FP7-HEALTH-2007-B,NEUGENE(2008), Centre National de la Recherche Scientifique (CNRS)-Service MIRCEN (MIRCEN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), cambon, karine, Infrastructures - Infrastructure de Recherche Translationnelle pour les Biothérapies en Neurosciences - - NeurATRIS2011 - ANR-11-INBS-0011 - INBS - VALID, Advanced gene therapy tools for treatment of CNS-specific disorders - NEUGENE - - EC:FP7:HEALTH2008-10-01 - 2012-03-31 - 222925 - VALID

المصدر: Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain-A Journal of Neurology, 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain
Brain, vol. 141, no. 5, pp. 1434-1454

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, Animals, Cells, Cultured, Corpus Striatum/enzymology, Disease Models, Animal, Down-Regulation/genetics, Electron Transport Complex IV/metabolism, Hand Strength/physiology, Huntingtin Protein/genetics, Huntington Disease/genetics, Huntington Disease/therapy, Macaca fascicularis, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Mutation/genetics, Neurons/metabolism, Phosphopyruvate Hydratase/metabolism, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism, RNA, Small Interfering/genetics, RNA, Small Interfering/metabolism, Trans-Activators/genetics, Trans-Activators/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Huntington, kinase, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV]Life Sciences [q-bio], Down-Regulation, neurons, Protein Serine-Threonine Kinases, Electron Transport Complex IV, Doublecortin-Like Kinases, mental disorders, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], RNA, Small Interfering, ComputingMilieux_MISCELLANEOUS, Huntingtin Protein, Hand Strength, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Original Articles, Corpus Striatum, Editor's Choice, Huntington Disease, nervous system, Phosphopyruvate Hydratase, Mutation, Trans-Activators, chromatin, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], transcription, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eb0c82958019d7f33356d092f6de6863
https://hal.archives-ouvertes.fr/hal-02459743

المؤلفون: Min Zi, Elizabeth J. Cartwright, Sangphil Oh, Ludwig Neyses, Simon G. Ray, Sukhpal Prehar, Delvac Oceandy, Riham Abou-Leisa, Dae-Sik Lim, Tamer M.A. Mohamed, Abigail Robertson, Arfa Maqsood

المصدر: The Journal of biological chemistry, 289(35), 24275-88. United States (2014).

مصطلحات موضوعية: Male, Genetically modified mouse, medicine.medical_specialty, animal structures, MAP Kinase Signaling System, Cardiac Hypertrophy, Cardiomegaly, Apoptosis, Protein Serine-Threonine Kinases, Biology, Serine-Threonine Kinase 3, Biochemistry, Proto-Oncogene Proteins c-raf/metabolism, Transgenic Mice, Muscle hypertrophy, Phenylephrine, Mice, Stress, Physiological, Cardiovascular Disease, Internal medicine, In Situ Nick-End Labeling, medicine, Animals, Humans, Protein kinase A, Molecular Biology, Cell Proliferation, Phenylephrine/adverse effects, Pressure overload, Hippo signaling pathway, Kinase, Regeneration (biology), fungi, Molecular Bases of Disease, Protein-Serine-Threonine Kinases/metabolism, Cell Biology, Systèmes cardiovasculaire & respiratoire [D03] [Sciences de la santé humaine], body regions, Proto-Oncogene Proteins c-raf, Mice, Inbred C57BL, Endocrinology, Genetic Polymorphism, Cardiomegaly/enzymology/pathology/physiopathology, Cardiovascular & respiratory systems [D03] [Human health sciences], Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6b486339c116fbe77e1c623eb1d455
https://doi.org/10.1074/jbc.m114.562405

المؤلفون: Boege, Yannick, Malehmir, Mohsen, Healy, Marc E., Bettermann, Kira, Lorentzen, Anna, Vucur, Mihael, Ahuja, Akshay K., Bohm, Friederike, Mertens, Joachim C., Shimizu, Yutaka, Frick, Lukas, Remouchamps, Caroline, Mutreja, Karun, Kahne, Thilo, Sundaravinayagam, Devakumar, Wolf, Monika J., Rehrauer, Hubert, Koppe, Christiane, Speicher, Tobias, Padrissa-Altes, Susagna, Maire, Renaud, Schattenberg, Jorn M., Jeong, Ju-Seong, Liu, Lei, Zwirner, Stefan, Boger, Regina, Huser, Norbert, Davis, Roger J., Mullhaupt, Beat, Moch, Holger, Schulze-Bergkamen, Henning, Clavien, Pierre-Alain, Werner, Sabine, Borsig, Lubor, Luther, Sanjiv A., Jost, Philipp J., Weinlich, Ricardo, Unger, Kristian, Behrens, Axel, Hillert, Laura, Dillon, Christopher, Di Virgilio, Michela, Wallach, David, Dejardin, Emmanuel, Zender, Lars, Naumann, Michael, Walczak, Henning, Green, Douglas R., Lopes, Massimo, Lavrik, Inna, Luedde, Tom, Heikenwalder, Mathias, Weber, Achim

المصدر: Cancer Cell, 32 (3), 342-359.e10 (2017)

مصطلحات موضوعية: Animals, Apoptosis, Carcinogenesis/metabolism/pathology, Carcinoma, Hepatocellular/pathology, Caspase 8/metabolism, Cell Proliferation, Cellular Senescence, Chronic Disease, Crosses, Genetic, DNA Damage, DNA Repair, Fas-Associated Death Domain Protein/metabolism, Female, Genomic Instability, Hepatectomy, Hepatocytes/pathology, Histones/metabolism, Humans, JNK Mitogen-Activated Protein Kinases/metabolism, Liver/metabolism/pathology, Liver Neoplasms/enzymology/pathology, Liver Regeneration, Male, Mice, Myeloid Cell Leukemia Sequence 1 Protein/metabolism, Phosphorylation, Receptor-Interacting Protein Serine-Threonine Kinases/metabolism, Receptors, Tumor Necrosis Factor, Type I/metabolism, Risk Factors, DNA damage response, hepatocellular carcinoma, liver, replication stress, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:1535-6108; urn:issn:1878-3686

URL الوصول: https://orbi.uliege.be/handle/2268/218283