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المؤلفون: Fatma Z. Guerfali, Hanène Attia, Youssef Gargouri, Pablo A. Leon Martinez, Ghada Mkannez, Aymen Bali, Dhafer Laouini, Imen Aissa, Rabiaa M. Sghaier
المساهمون: Laboratoire de Transmission, Contrôle et Immunobiologie des Infections - Laboratory of Transmission, Control and Immunobiology of Infection (LR11IPT02), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), École Nationale d'Ingénieurs de Sfax | National School of Engineers of Sfax (ENIS), This work received financial support from the Tunisian Ministry of Higher Education and Scientific Research to the Transmission, Control and Immunobiology of Infections Laboratory (LR11IPT02, D. Laouini)., We thank Mr A. Marouani and Dr Z. Ben Lasfer (Animal Facilities of the Institut Pasteur de Tunis) for their help conducting this study. We are also grateful to Ms S. Amouri for her help and thankful to Dr K. Ben-Aissa (Washignton, USA) and Dr S. Gritli (Department of Oto-Rhino-Laryngology, Charles Nicolle Hospital, Tunis, Tunisia) for their critical reading and grammar corrections
المصدر: Parasitology
Parasitology, Cambridge University Press (CUP), 2016, 143 (12), pp.1615-1620. ⟨10.1017/S0031182016001086⟩مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Pharmacology, Parasite load, Mice, parasite load, 0302 clinical medicine, MESH: Animals, Leishmania major, MESH: Th1 Cells/immunology, Mice, Inbred BALB C, MESH: Leishmaniasis, Cutaneous/drug therapy, MESH: Tyrosine/analogs & derivatives, 3. Good health, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Infectious Diseases, 030220 oncology & carcinogenesis, Cytokines, Leishmania infantum, Injections, Subcutaneous, lipophilic tyrosyl ester, Antiprotozoal Agents, MESH: Mice, Inbred BALB C, Leishmaniasis, Cutaneous, MESH: Antiprotozoal Agents/administration & dosage, MESH: Leishmania major/drug effects, Biology, BALB/c, 03 medical and health sciences, Cutaneous leishmaniasis, In vivo, MESH: Tyrosine/pharmacology, medicine, Animals, Immunologic Factors, MESH: Mice, anti-leishmanial activity, MESH: Injections, Subcutaneous, Th1 Cells, biology.organism_classification, medicine.disease, Leishmania, In vitro, MESH: Parasite Load, MESH: Immunologic Factors/administration & dosage, Disease Models, Animal, 030104 developmental biology, Immunology, Tyrosine, Animal Science and Zoology, Parasitology, MESH: Cytokines/metabolism, MESH: Disease Models, Animal
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المصدر: Scientific Reports
Scientific reports, vol. 6, pp. 33458مصطلحات موضوعية: 0301 basic medicine, Simvastatin, Necrosis, Administration, Topical, 030106 microbiology, Ear infection, Leishmaniasis, Cutaneous, Severity of Illness Index, Article, 03 medical and health sciences, Cutaneous leishmaniasis, Phagosomes, Phagosome maturation, medicine, Macrophage, Animals, Leishmania major, Parasites, Respiratory Burst, Mice, Inbred BALB C, Multidisciplinary, biology, Dose-Response Relationship, Drug, Intracellular parasite, Macrophages, Hydrogen Peroxide, biology.organism_classification, medicine.disease, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Cytokines/biosynthesis, Hydrogen Peroxide/metabolism, Leishmania major/drug effects, Leishmaniasis, Cutaneous/drug therapy, Leishmaniasis, Cutaneous/immunology, Leishmaniasis, Cutaneous/parasitology, Macrophages/drug effects, Macrophages/metabolism, Parasites/drug effects, Phagosomes/drug effects, Phagosomes/metabolism, Respiratory Burst/drug effects, Simvastatin/administration & dosage, Simvastatin/pharmacology, Simvastatin/therapeutic use, Immunology, Cytokines, lipids (amino acids, peptides, and proteins), medicine.symptom, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Valérie Jullian, Denis Castillo, Michel Sauvain, Marion Rivaud
المساهمون: Universidad Peruana Cayetano Heredia (UPCH), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)
المصدر: Planta Medica
Planta Medica, 2014, 80 (11), pp.902-906. ⟨10.1055/s-0034-1382826⟩
Planta Medica, Georg Thieme Verlag, 2014, 80 (11), pp.902-906. ⟨10.1055/s-0034-1382826⟩مصطلحات موضوعية: benzo[c]phenanthridines, Zanthoxylum, Phenanthridines/chemistry/isolation & purification/pharmacology, Plant Extracts/chemistry/isolation & purification/pharmacology, [SDV]Life Sciences [q-bio], Pharmaceutical Science, leishmanicidal, Benzophenanthridines/chemistry/isolation & purification/pharmacology, Plant Bark/chemistry, Plant Roots, Analytical Chemistry, chemistry.chemical_compound, Mice, Macrophages/drug effects, Zanthoxylum rhoifolium, Parasitic Sensitivity Tests, Drug Discovery, Axenic, Leishmaniasis, Leishmania, Mice, Inbred BALB C, biology, in vitro, Benzo[c]phenanthridines, 3. Good health, Phenanthridines, purl.org/pe-repo/ocde/ford#1.04.01 [https], in vivo, Plant Bark, Molecular Medicine, Female, Cell Survival/drug effects, Stereochemistry, Cell Survival, purl.org/pe-repo/ocde/ford#1.06.03 [https], Leishmaniasis, Cutaneous, Inhibitory Concentration 50, Cutaneous leishmaniasis, In vitro, In vivo, medicine, Animals, Humans, purl.org/pe-repo/ocde/ford#3.01.05 [https], Leishmaniasis, Cutaneous/drug therapy/parasitology, Amastigote, purl.org/pe-repo/ocde/ford#1.04.07 [https], leishmaniasis, Rutaceae, Pharmacology, Benzophenanthridines, Plant Roots/chemistry, Plants, Medicinal, Plant Extracts, Macrophages, Organic Chemistry, Leishmania/drug effects, medicine.disease, biology.organism_classification, Molecular biology, Zanthoxylum/chemistry, Disease Models, Animal, Chelerythrine, Complementary and alternative medicine, chemistry, Leishmania amazonensis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed225a60e72e20ee63a518123276bbaa
https://pubmed.ncbi.nlm.nih.gov/25029171
