المؤلفون: Camilleri P; Bio-Chemical Solutions, Stevenage, UK., Soldo B; Aerpio Pharmaceuticals, Cincinnati, OH, USA., Buch A; Aerpio Pharmaceuticals, Cincinnati, OH, USA., Janusz J; Aerpio Pharmaceuticals, Cincinnati, OH, USA.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Oct; Vol. 51 (10), pp. 1110-1121. Date of Electronic Publication: 2021 Sep 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Microsomes, Liver*/metabolism , Tandem Mass Spectrometry*, Acid Phosphatase/metabolism ; Aniline Compounds ; Chromatography, Liquid ; Cytochrome P-450 CYP2C8/metabolism ; Humans ; Oxidation-Reduction ; Oxidative Stress ; Sulfonic Acids

المؤلفون: Yin W; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China., Zhou X, Qiao J, Zhu L

المصدر: Biomedical chromatography : BMC [Biomed Chromatogr] 2012 May; Vol. 26 (5), pp. 666-71. Date of Electronic Publication: 2011 Sep 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*blood , Aniline Compounds/*pharmacokinetics , Chromatography, High Pressure Liquid/*methods , Ethylene Glycols/*blood , Ethylene Glycols/*pharmacokinetics , Microsomes, Liver/*metabolism , Tandem Mass Spectrometry/*methods, Aniline Compounds/chemistry ; Aniline Compounds/metabolism ; Animals ; Drug Stability ; Ethylene Glycols/chemistry ; Ethylene Glycols/metabolism ; Linear Models ; Male ; Rats ; Rats, Sprague-Dawley ; Reproducibility of Results ; Sensitivity and Specificity

المؤلفون: Marchenko MM, Kopyl'chuk HP, Shmarakov IO, Buchkovs'ka IM

المصدر: Ukrains'kyi biokhimichnyi zhurnal (1999 ) [Ukr Biokhim Zh (1999)] 2012 Mar-Apr; Vol. 84 (2), pp. 42-7.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Nat︠s︡ionalʹna akademii︠a︡ nauk Ukraïny, Instytut biokhimiï im. O.V. Palladina Country of Publication: Ukraine NLM ID: 101657175 Publication Model: Print Cited Medium: Print NLM ISO Abbreviation: Ukr Biokhim Zh (1999) Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*metabolism , Aniline Hydroxylase/*metabolism , Glutathione Transferase/*metabolism , Liver/*enzymology , Microsomes, Liver/*enzymology , Oxidoreductases, N-Demethylating/*metabolism , Vitamin A Deficiency/*metabolism, Acyltransferases/deficiency ; Acyltransferases/genetics ; Aniline Compounds/toxicity ; Animals ; Diet ; Glutathione/metabolism ; Inactivation, Metabolic ; Liver/drug effects ; Mice ; Mice, Knockout ; Microsomes, Liver/drug effects ; Vitamin A/metabolism

المؤلفون: Zhang C; Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080, United States., Kenny JR, Le H, Deese A, Ford KA, Lightning LK, Fan PW, Driscoll JP, Halladay JS, Hop CE, Khojasteh SC

المصدر: Chemical research in toxicology [Chem Res Toxicol] 2011 Oct 17; Vol. 24 (10), pp. 1668-77. Date of Electronic Publication: 2011 Sep 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Halogenation* , Metabolic Detoxication, Phase II*, Aniline Compounds/*metabolism , Glutathione/*metabolism , Microsomes, Liver/*metabolism, Aniline Compounds/chemistry ; Chromatography, Liquid ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Structure ; NADP/metabolism ; Structure-Activity Relationship

المؤلفون: Ulgen M; University of Marmara, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Istanbul, Turkey., Ozer U, Kucukguzel I, Gorrod JW

المصدر: Drug metabolism and drug interactions [Drug Metabol Drug Interact] 1997; Vol. 14 (2), pp. 83-98.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: De Gruyter Country of Publication: Germany NLM ID: 8904736 Publication Model: Print Cited Medium: Print ISSN: 0792-5077 (Print) Linking ISSN: 07925077 NLM ISO Abbreviation: Drug Metabol Drug Interact Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*metabolism , Microsomes, Liver/*metabolism, Aniline Compounds/chemistry ; Animals ; Chemical Phenomena ; Chemistry, Physical ; Chromatography, High Pressure Liquid ; Chromatography, Thin Layer ; Cricetinae ; Dealkylation ; Mesocricetus ; Toluidines/chemistry ; Toluidines/metabolism

المؤلفون: Rietjens IM; Department of Biochemistry, Agricultural University, Wageningen, The Netherlands., Vervoort J

المصدر: Chemico-biological interactions [Chem Biol Interact] 1991; Vol. 77 (3), pp. 263-81.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print Cited Medium: Print ISSN: 0009-2797 (Print) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*pharmacokinetics , Benzoquinones/*metabolism , Imines/*metabolism , Microsomes, Liver/*metabolism, Aniline Compounds/metabolism ; Animals ; Biotransformation ; Cytochrome P-450 Enzyme System/metabolism ; Magnetic Resonance Spectroscopy ; Male ; NADP/pharmacology ; Rats ; Rats, Inbred Strains

المؤلفون: Wang R; Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China., Chen J, Qin BJ, Xie JW, Li H, Xie L

المصدر: Yao xue xue bao = Acta pharmaceutica Sinica [Yao Xue Xue Bao] 2012 Dec; Vol. 47 (12), pp. 1671-7.

نوع المنشور: English Abstract; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Zhongguo yao xue hui Country of Publication: China NLM ID: 21710340R Publication Model: Print Cited Medium: Print ISSN: 0513-4870 (Print) Linking ISSN: 05134870 NLM ISO Abbreviation: Yao Xue Xue Bao Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*metabolism , Microsomes, Liver/*metabolism , Reverse Transcriptase Inhibitors/*metabolism, Aniline Compounds/chemistry ; Aniline Compounds/metabolism ; Animals ; Anti-HIV Agents/chemistry ; Chromatography, High Pressure Liquid ; Molecular Structure ; Pyridines/chemistry ; Pyridines/metabolism ; Rats ; Reverse Transcriptase Inhibitors/chemistry ; Spectrometry, Mass, Electrospray Ionization

المؤلفون: Myasoedova KN; Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia. KseniaMyasoedova@gmail.com, Timofeev KN

المصدر: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2010 Jul; Vol. 75 (7), pp. 899-904.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MAIK Nauka/Interperiodica Country of Publication: United States NLM ID: 0376536 Publication Model: Print Cited Medium: Internet ISSN: 1608-3040 (Electronic) Linking ISSN: 00062979 NLM ISO Abbreviation: Biochemistry (Mosc) Subsets: MEDLINE

مواضيع طبية MeSH: Catalytic Domain*, Aryl Hydrocarbon Hydroxylases/*chemistry , Microsomes, Liver/*enzymology, Aniline Compounds/chemistry ; Aniline Compounds/metabolism ; Animals ; Aryl Hydrocarbon Hydroxylases/metabolism ; Benzphetamine/chemistry ; Benzphetamine/metabolism ; Cytochrome P450 Family 2 ; Heme/chemistry ; Heme/metabolism ; Ligands ; Microsomes, Liver/chemistry ; Protein Binding ; Protein Conformation ; Rabbits ; Substrate Specificity

المؤلفون: Shaw J; Unitech Pharmaceuticals, Inc., Ann Arbor, MI 48108, USA. jshaw@21-cti.com, Shay B, Jiang J, Valeriote F, Chen B

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2012 Jun; Vol. 37 (2), pp. 83-9. Date of Electronic Publication: 2011 Nov 05.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0378-7966 (Print) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Chromatography, Liquid/*methods , Isoxazoles/*metabolism , Microsomes, Liver/*metabolism , Tandem Mass Spectrometry/*methods, Aniline Compounds/metabolism ; Animals ; Isoxazoles/chemistry ; Leflunomide ; Mice ; Mice, Inbred ICR ; Tumor Necrosis Factor-alpha/antagonists & inhibitors

المؤلفون: Naiman K; Department of Biochemistry, Faculty of Science, Charles University, Prague, Czech Republic., Frei E, Stiborova M

المصدر: Neuro endocrinology letters [Neuro Endocrinol Lett] 2010; Vol. 31 Suppl 2, pp. 36-45.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society of Integrated Sciences Country of Publication: Sweden NLM ID: 8008373 Publication Model: Print Cited Medium: Print ISSN: 0172-780X (Print) Linking ISSN: 0172780X NLM ISO Abbreviation: Neuro Endocrinol Lett Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*metabolism , Anisoles/*metabolism , Carcinogens/*metabolism , Cytochrome P-450 Enzyme System/*physiology , Environmental Pollutants/*metabolism , Hydroxylamine/*metabolism , Microsomes, Liver/*metabolism, Animals ; Aryl Hydrocarbon Hydroxylases/physiology ; Cytochrome P-450 CYP2E1/physiology ; Male ; Models, Animal ; Oxidation-Reduction ; Rats ; Rats, Wistar ; Steroid Hydroxylases/physiology