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1
المؤلفون: Hoa H.N. Pham, Junya Fukuoka, Qi Wang, Xingzhi Song, Ming Chen, Lauren Averett Byers, Lixia Diao, Won-Chul Lee, Yanhua Tian, Julie George, Shawna M Hubert, Bo Zhu, Xiao Hu, Ying Jin, Nicholas McGranahan, Chang-Jiun Wu, J. Jack Lee, Jing Wang, Carmen Behrens, Jianjun Zhang, Alexandre Reuben, Xin Hu, Jun Li, Roman K. Thomas, Latasha Little, Ignacio I. Wistuba, Junya Fujimoto, Jia Wu, Jiexin Zhang, Edwin R. Parra, Xiuning Le, John V. Heymach, Curtis Gumbs, Robert J. Cardnell, Bonnie S. Glisson, Meijuan Wu, Yamei Chen, Chao Cheng, William N. William, Don L. Gibbons, Runzhe Chen, Chi-Wan Chow, P. Andrew Futreal, Jianhua Zhang
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communicationsمصطلحات موضوعية: Adult, Male, Lung Neoplasms, DNA Copy Number Variations, T-Lymphocytes, Tumour heterogeneity, medicine.medical_treatment, Science, Cell, Receptors, Antigen, T-Cell, Loss of Heterozygosity, General Physics and Astronomy, Biology, Article, Small-cell lung cancer, General Biochemistry, Genetics and Molecular Biology, Genetic Heterogeneity, Interferon-gamma, HLA Antigens, Carcinoma, Non-Small-Cell Lung, Exome Sequencing, Cancer genomics, medicine, Humans, Lung cancer, Gene, Exome, neoplasms, Aged, Aged, 80 and over, Multidisciplinary, Lung, T-cell receptor, General Chemistry, Immunotherapy, Middle Aged, medicine.disease, Small Cell Lung Carcinoma, Survival Analysis, humanities, respiratory tract diseases, medicine.anatomical_structure, Mutation, Cancer research, Tumour immunology, Immunohistochemistry, Female, Signal Transduction
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2
المؤلفون: L. Jeffrey Medeiros, Siba El Hussein, David A. Jaffray, Ignacio I. Wistuba, Joseph D. Khoury, Pingjun Chen, Jia Wu
المصدر: J Pathol
مصطلحات موضوعية: Adult, Male, Chronic lymphocytic leukemia, Diagnostic accuracy, Article, Pathology and Forensic Medicine, Artificial Intelligence, hemic and lymphatic diseases, Biomarkers, Tumor, medicine, Humans, In patient, Aged, Richter transformation, business.industry, Disease progression, Middle Aged, Prognosis, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Cell Transformation, Neoplastic, Disease Progression, Biomarker (medicine), Female, Lymphoma, Large B-Cell, Diffuse, Artificial intelligence, business, Progressive disease
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3
المؤلفون: John V. Heymach, Barbara Mino, J. Jack Lee, Pedro Rocha, Cesar A. Moran, David C. Rice, Edwin R. Parra, Humam Kadara, Boris Sepesi, Lei Feng, Luisa M. Solis, Carmen Behrens, Ignacio I. Wistuba, Don L. Gibbons, Jianjun Zhang, Chad J. Creighton, Jaime Rodriguez-Canales
المصدر: Clinical Lung Cancer. 22:e415-e424
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Adenocarcinoma of Lung, Gene mutation, Logistic regression, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Germline mutation, Immune system, AMP-Activated Protein Kinase Kinases, Internal medicine, medicine, Humans, Lung cancer, Immune Checkpoint Inhibitors, Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, business.industry, Immunotherapy, Middle Aged, medicine.disease, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Adenocarcinoma, Female, business, CD8
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4
المؤلفون: Cheuk Hong Leung, Wayne L. Hofstetter, John V. Heymach, Alexandre Reuben, Myrna C.B. Godoy, Ara A. Vaporciyan, Padmanee Sharma, Yasir Elamin, Neda Kalhor, Robert R. Jenq, Junya Fujimoto, Tina Cascone, Anne S. Tsao, William N. William, Charles Lu, Frank E. Mott, Nadim J. Ajami, Don L. Gibbons, Jack A. Roth, David C. Rice, Luisa M. Solis, Hai T. Tran, Brett W. Carter, Lauren Averett Byers, Andrew Futreal, Lorenzo Federico, Annikka Weissferdt, Garrett L. Walsh, Reza J. Mehran, Chantale Bernatchez, George R. Blumenschein, Jennifer A. Wargo, Heather Lin, Cara Haymaker, Xiuning Le, Jonathan M. Kurie, Mehmet Altan, James P. Allison, Stephen G. Swisher, Edwin R. Parra, Boris Sepesi, Hitoshi Dejima, Frank V. Fossella, Jianjun Zhang, Bonnie S. Glisson, Mara B. Antonoff, Abdul Wadud Khan, Apar Pataer, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Humam Kadara, J. Jack Lee, Ferdinandos Skoulidis
المصدر: Nat Med
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Ipilimumab, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Clinical endpoint, Carcinoma, Humans, Medicine, Lung cancer, Neoadjuvant therapy, Aged, Chemotherapy, business.industry, General Medicine, Middle Aged, medicine.disease, Neoadjuvant Therapy, Clinical trial, Nivolumab, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, business, medicine.drug
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5
المؤلفون: Pedro Rocha, Dzifa Y. Douse, Lixia Diao, Humam Kadara, Jianjun Zhang, Debora A. Ledesma, Jose Luis Solorzano, John V. Heymach, Ruth Salazar, Luisa M. Solis, Neda Kalhor, Barbara Mino, J. Jack Lee, Don L. Gibbons, Cesar A. Moran, David C. Rice, Carmen Behrens, Pamela Villalobos, Ara A. Vaporciyan, Jiexin Zhang, Hitoshi Dejima, Annikka Weissferdt, Kyle G. Mitchell, Tina Cascone, Edwin Parra-Cuentas, Boris Sepesi, Xiuning Le, Ignacio I. Wistuba
المصدر: Cancer Immunology, Immunotherapy
مصطلحات موضوعية: Male, Lung adenocarcinoma, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Immune profiling, Atypical hyperplasia, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Immunology and Allergy, 5'-Nucleotidase, Neoadjuvant therapy, Aged, 80 and over, 0303 health sciences, biology, Immunosuppression, Middle Aged, Prognosis, Oncology, 030220 oncology & carcinogenesis, Adenocarcinoma, Immunohistochemistry, Female, Original Article, medicine.symptom, Adult, PD-L1, Immunology, Adenocarcinoma of Lung, Inflammation, GPI-Linked Proteins, 03 medical and health sciences, Immune system, Biomarkers, Tumor, medicine, Humans, Immunologic Factors, Aged, Retrospective Studies, 030304 developmental biology, business.industry, Correction, medicine.disease, Adenosinergic pathway, CD73, Cancer research, biology.protein, business, Follow-Up Studies
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6
المؤلفون: Myrna C.B. Godoy, Jean Pierre J. Issa, Hoa H.N. Pham, Humam Kadara, Alexandre Reuben, Paul Scheet, Ignacio I. Wistuba, Dan Su, Ara A. Vaporciyan, Chi Wan Chow, P. Andrew Futreal, Xin Hu, Runzhe Chen, Linghua Wang, Lisha Ying, J. Jack Lee, Jianhua Zhang, Boris Sepesi, Harvey I. Pass, John V. Heymach, Jian Carrot-Zhang, Carmen Behrens, Junya Fujimoto, Junya Fukuoka, Marcos R. Estecio, Jianjun Zhang, Brett W. Carter, Nicholas McGranahan, Yue Lu, Mara B. Antonoff
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communicationsمصطلحات موضوعية: Male, Epigenomics, 0301 basic medicine, Lung Neoplasms, Carcinogenesis, General Physics and Astronomy, medicine.disease_cause, Epigenome, 0302 clinical medicine, Mutation Rate, Chromosome instability, Tumor Microenvironment, Cancer genomics, Copy-number variation, Lung, Aged, 80 and over, Mutation, Multidisciplinary, Methylation, Middle Aged, 030220 oncology & carcinogenesis, Reduced representation bisulfite sequencing, DNA methylation, Disease Progression, Adenocarcinoma, Female, Adult, DNA Copy Number Variations, Tumour heterogeneity, Science, Adenocarcinoma of Lung, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Genetic Heterogeneity, 03 medical and health sciences, Chromosomal Instability, medicine, Humans, Atypical adenomatous hyperplasia, Aged, Hyperplasia, General Chemistry, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Mutagenesis, Cancer research, Precancerous Conditions, Non-small-cell lung cancer
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7
المؤلفون: Kyle G. Mitchell, Edwin R. Parra, Jiexin Zhang, David B. Nelson, Erin M. Corsini, Pamela Villalobos, Cesar A. Moran, Ferdinandos Skoulidis, Ignacio I. Wistuba, Junya Fujimoto, Jack A. Roth, Mara B. Antonoff, J. Jack Lee, Ara A. Vaporciyan, Wayne L. Hofstetter, Reza J. Mehran, Stephen G. Swisher, David C. Rice, Boris Sepesi, Garrett L. Walsh, Carmen Behrens, Neda Kalhor, Annikka Weissferdt, John V. Heymach, null AstraZeneca, null Bayer, null GlaxoSmithKline
المصدر: Ann Thorac Surg
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, STK11, Adenocarcinoma of Lung, Protein Serine-Threonine Kinases, 030204 cardiovascular system & hematology, Disease-Free Survival, Article, 03 medical and health sciences, 0302 clinical medicine, AMP-Activated Protein Kinase Kinases, Internal medicine, PD-L1, Biomarkers, Tumor, medicine, Humans, Clinical significance, Aged, Neoplasm Staging, Retrospective Studies, Lung, Tissue microarray, biology, Cluster of differentiation, business.industry, FOXP3, Middle Aged, Prognosis, medicine.disease, medicine.anatomical_structure, 030228 respiratory system, biology.protein, Adenocarcinoma, Female, Surgery, Neoplasm Recurrence, Local, Cardiology and Cardiovascular Medicine, business
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8
المؤلفون: Ming Tang, Hussein A. Abbas, Marcelo V. Negrao, Maheshwari Ramineni, Xin Hu, Shawna Marie Hubert, Junya Fujimoto, Alexandre Reuben, Susan Varghese, Jianhua Zhang, Jun Li, Chi-Wan Chow, Xizeng Mao, Xingzhi Song, Won-Chul Lee, Jia Wu, Latasha Little, Curtis Gumbs, Carmen Behrens, Cesar Moran, Annikka Weissferdt, J. Jack Lee, Boris Sepesi, Stephen Swisher, Chao Cheng, Jonathan Kurie, Don Gibbons, John V. Heymach, Ignacio I. Wistuba, P. Andrew Futreal, Neda Kalhor, Jianjun Zhang
المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)مصطلحات موضوعية: Lung Neoplasms, Science, Tumour heterogeneity, General Physics and Astronomy, Adenocarcinoma, General Biochemistry, Genetics and Molecular Biology, Article, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Exome Sequencing, Cancer genomics, Humans, Aged, Multidisciplinary, Gene Expression Profiling, General Chemistry, Genomics, respiratory system, Middle Aged, Small Cell Lung Carcinoma, respiratory tract diseases, Carcinoma, Neuroendocrine, Gene Expression Regulation, Neoplastic, Phenotype, Carcinoma, Squamous Cell, Carcinoma, Large Cell, Lung cancer, Transcriptome
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9
المؤلفون: J. Jack Lee, John V. Heymach, Cesar A. Moran, Jack A. Roth, Ignacio I. Wistuba, Apar Pataer, Ara A. Vaporciyan, Boris Sepesi, Arlene M. Correa, Neda Kalhor, Stephen G. Swisher, Tina Cascone, Annikka Weissferdt, Jitesh B. Shewale, Wayne L. Hofstetter
المصدر: Clin Lung Cancer
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Pathological response, Article, 03 medical and health sciences, 0302 clinical medicine, Neoadjuvant treatment, Major Pathologic Response, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Lung cancer, Aged, Retrospective Studies, Aged, 80 and over, Chemotherapy, business.industry, Surrogate endpoint, Hazard ratio, Middle Aged, Prognosis, medicine.disease, Neoadjuvant Therapy, Survival Rate, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, business, Follow-Up Studies
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10
المؤلفون: Hui Liu, Sergio Pina-Oviedo, Roberto N. Miranda, Ken H. Young, John Stewart, Mark W. Clemens, Andrés E. Quesada, Ellen J. Schlette, Sanam Loghavi, Yun Wu, Alonso R. Miranda, Ignacio I. Wistuba, Carlos E. Bueso-Ramos, Siaw Ming Chai, L. Jeffrey Medeiros, Kirill A. Lyapichev, Arthy Yoga, Sanat K. Dave, Maria C. Ferrufino-Schmidt, Mark G. Evans, Arianna Di Napoli, Kelly K. Hunt, Joseph D. Khoury, Mitual Amin
المصدر: Mod Pathol
مصطلحات موضوعية: Adult, 0301 basic medicine, Pathology, medicine.medical_specialty, CD30, Surface Properties, Biopsy, breast capsule, Ki-1 Antigen, Breast Neoplasms, Prosthesis Design, Article, Specimen Handling, Workflow, Pathology and Forensic Medicine, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Biomarkers, Tumor, Humans, Medicine, In patient, Breast Implantation, Anaplastic large-cell lymphoma, Aged, business.industry, Capsule, Middle Aged, Models, Theoretical, medicine.disease, Immunohistochemistry, Lymphoma, Gross examination, breast implants, 030104 developmental biology, Effusion, anaplastic large cell lymphoma, 030220 oncology & carcinogenesis, Breast implant, Lymphoma, Large-Cell, Anaplastic, Female, T-cell lymphoma, business