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المؤلفون: William Pei, Radhakrishnan Mahadevan, Leo Zhu, Ines Thiele
المصدر: PLoS Computational Biology, Vol 17, Iss 8, p e1009110 (2021)
PLoS Computational Biologyمصطلحات موضوعية: Male, Enzyme Metabolism, Alcohol, Pharmacology, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Drug Metabolism, Disulfiram, Medicine and Health Sciences, Metabolites, Tissue Distribution, Biology (General), Enzyme Chemistry, 0303 health sciences, Alcohol Consumption, Ecology, biology, Organic Compounds, Aldehyde Dehydrogenase, Mitochondrial, 3. Good health, Enzymes, Alcoholism, Chemistry, Computational Theory and Mathematics, Liver, Modeling and Simulation, Physical Sciences, medicine.drug, Research Article, Physiologically based pharmacokinetic modelling, QH301-705.5, Acetaldehyde Dehydrogenase Inhibitors, Acetaldehyde, Models, Biological, 03 medical and health sciences, Cellular and Molecular Neuroscience, Genetics, medicine, Humans, Computer Simulation, Pharmacokinetics, Ethanol metabolism, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Alcohol dehydrogenase, ALDH2, Nutrition, Ethanol, Organic Chemistry, Chemical Compounds, Computational Biology, Biology and Life Sciences, Proteins, Diet, Kinetics, Metabolism, chemistry, Intestinal Absorption, Alcohols, biology.protein, Enzymology, 030217 neurology & neurosurgery, Alcohol Deterrents
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المصدر: PLoS Computational Biology. San Francisco, CA: Public Library of Science (2017).
PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 5, p e1005544 (2017)مصطلحات موضوعية: 0301 basic medicine, Microbiologie [F11] [Sciences du vivant], simulation of microbial communities, Physiology, Microbial metabolism, flux balance analysis, Gut flora, Pathology and Laboratory Medicine, Biochemistry, biofilm, Multidisciplinaire, généralités & autres [F99] [Sciences du vivant], Glucose Metabolism, Metabolites, Medicine and Health Sciences, Microbiology [F11] [Life sciences], Biology (General), Ecology, Simulation and Modeling, Community structure, Pseudomonas Aeruginosa, Oxygen Metabolism, Microbial Physiology, Bacterial Pathogens, Body Fluids, Flux balance analysis, Cell metabolism, Computational Theory and Mathematics, Medical Microbiology, Modeling and Simulation, Carbohydrate Metabolism, Pathogens, Anatomy, microbial physiology, Research Article, Cell Physiology, QH301-705.5, Microbial Consortia, 030106 microbiology, Niche, Computational biology, Multidisciplinary, general & others [F99] [Life sciences], Biology, Research and Analysis Methods, Models, Biological, Microbiology, 03 medical and health sciences, Cellular and Molecular Neuroscience, Pseudomonas, Genetics, Humans, Microbial Pathogens, Molecular Biology, cross-feeding, Ecology, Evolution, Behavior and Systematics, Bacteria, gut microbiota, Organisms, Biofilm, Biology and Life Sciences, Bacteriology, agent-based modeling, Cell Biology, biology.organism_classification, Metabolic Flux Analysis, Gastrointestinal Microbiome, Cell Metabolism, Mucus, Metabolism, 030104 developmental biology, Biofilms, Microbial Interactions, Bacterial Biofilms
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5fc8c32dff35011c5d6603c5953685
http://orbilu.uni.lu/handle/10993/30995 -
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المؤلفون: Ines Thiele, Ronan M. T. Fleming
المساهمون: [ 1 ] Univ Iceland, Ctr Syst Biol, IS-101 Reykjavik, Iceland [ 2 ] Univ Iceland, Fac Med, Dept Biochem & Mol Biol, IS-101 Reykjavik, Iceland [ 3 ] Univ Iceland, Fac Ind Engn Mech Engn & Comp Sci, IS-101 Reykjavik, Iceland
المصدر: Journal of Theoretical Biology. 314:173-181
مصطلحات موضوعية: Statistics and Probability, Thermodynamic equilibrium, Molecular Networks (q-bio.MN), Trypanosoma brucei brucei, Thermodynamics, Kinetic energy, Models, Biological, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Reaction rate, 03 medical and health sciences, 0103 physical sciences, Quantitative Biology - Molecular Networks, Anaerobiosis, Statistical physics, Time complexity, 030304 developmental biology, Physics, 0303 health sciences, Forcing (recursion theory), 010304 chemical physics, General Immunology and Microbiology, Applied Mathematics, General Medicine, State (functional analysis), Enzymes, Living systems, Molecular Weight, Kinetics, FOS: Biological sciences, Modeling and Simulation, Steady state (chemistry), General Agricultural and Biological Sciences, Glycolysis
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المؤلفون: Michael A. Saunders, Ronan M. T. Fleming, Ines Thiele, Nikos Vlassis
المصدر: Journal of Theoretical Biology, 409, 1-10. Academic Press
مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Concentration, Duality, Molecular Networks (q-bio.MN), Duality (optimization), Disjoint sets, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, Biochemical network, 03 medical and health sciences, Flux (metallurgy), Modelling and Simulation, Immunology and Microbiology(all), Quantitative Biology - Molecular Networks, Computer Simulation, Mathematics, Medicine(all), Discrete mathematics, Flux, Computational model, Agricultural and Biological Sciences(all), General Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology(all), Applied Mathematics, General Medicine, Dual (category theory), Kinetics, Range (mathematics), 030104 developmental biology, Modeling and Simulation, FOS: Biological sciences, Mathematical structure, General Agricultural and Biological Sciences, Biological system
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becf67fe83adc7832da06130f79d39bc
https://europepmc.org/articles/PMC5048525/ -
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المؤلفون: Ines Thiele, Gregory Provan, Ronan M. T. Fleming, Heinz-Peter Nasheuer
المصدر: Journal of Theoretical Biology. 264:683-692
مصطلحات موضوعية: pathways, Second law of thermodynamics, constraint-based modelling, microarrays, Conservation of mass, high-throughput, media_common, Quantitative Biology::Molecular Networks, Applied Mathematics, systems biology, linear polytope, General Medicine, fluxes, Exponential function, Flux balance analysis, Modeling and Simulation, Thermodynamics, Systems biology, General Agricultural and Biological Sciences, Biological system, Algorithms, Statistics and Probability, reconstruction, constraint, Constraint-based modelling, biochemical networks, media_common.quotation_subject, Logarithmic polytope, Biology, Bacterial Physiological Phenomena, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, scale, Linear polytope, Escherichia coli, Computer Simulation, algebraic geometry, logarithmic polytope, General Immunology and Microbiology, Numerical analysis, Feasible region, Computational Biology, balance, Algebraic geometry, Kinetics, escherichia-coli, Steady state (chemistry), Energy Metabolism
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المؤلفون: Ronan M. T. Fleming, Maike K. Aurich, Ines Thiele
المصدر: PLoS Computational Biology, Vol 13, Iss 8, p e1005698 (2017)
PLoS Computational Biologyمصطلحات موضوعية: Melanomas, 0301 basic medicine, Physiology, Cell, Biochemistry, Drug Metabolism, Metabolites, Medicine and Health Sciences, Biology (General), Databases, Protein, Melanoma, Ecology, Systems Biology, Phenotype, Isocitrate Dehydrogenase, Oxygen Metabolism, Chemistry, medicine.anatomical_structure, Oncology, Computational Theory and Mathematics, Modeling and Simulation, Physical Sciences, Metabolome, Research Article, Chemical Elements, Cell Physiology, Cell type, QH301-705.5, Biology, Models, Biological, 03 medical and health sciences, Cellular and Molecular Neuroscience, Metabolomics, Cell Line, Tumor, Biomarkers, Tumor, Genetics, medicine, Extracellular, Humans, Pharmacokinetics, Molecular Biology, Secretion, Ecology, Evolution, Behavior and Systematics, Pharmacology, Biology and Life Sciences, Cancers and Neoplasms, Cancer, Cell Biology, medicine.disease, Cell Metabolism, Oxygen, Metabolism, 030104 developmental biology, Cancer cell, Physiological Processes
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المؤلفون: Bernhard O. Palsson, Ines Thiele, Ottar Rolfsson
المساهمون: Addresses: [Show the Organization-Enhanced name(s)] [ 1 ] Univ Iceland, Ctr Syst Biol, IS-101 Reykjavik, Iceland [Show the Organization-Enhanced name(s)] [ 2 ] Univ Iceland, Fac Ind Engn Mech Engn & Comp Sci, IS-101 Reykjavik, Iceland
المصدر: BMC Systems Biology
BMC Systems Biology, Vol 5, Iss 1, p 155 (2011)مصطلحات موضوعية: 0303 health sciences, Systems biology, Systems Biology, Applied Mathematics, Metabolic network, Computational Biology, Genome project, Computational biology, Biology, Models, Biological, Computer Science Applications, 03 medical and health sciences, 0302 clinical medicine, lcsh:Biology (General), Structural Biology, Modeling and Simulation, Modelling and Simulation, Humans, lcsh:QH301-705.5, Molecular Biology, 030217 neurology & neurosurgery, Algorithms, Metabolic Networks and Pathways, 030304 developmental biology, Research Article
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المؤلفون: Sook-il Shin, Bernhard O. Palsson, Joshua N. Adkins, Sigrid C. J. De Keersmaecker, Jennifer L. Reed, Suresh Sudarsan, Dirk Bumann, Feng-Chi Chen, Yu-Chieh Liao, Ines Thiele, Chao A. Hsiung, Pep Charusanti, Ronan M. T. Fleming, Inge Thijs, Jonas Steinmann, Guy Fankam, Douglas K. Allen, Sara Sigurbjörnsdóttir, Karsten Zengler, Susanna Bazzani, Anu Raghunathan, Daniel R. Hyduke, Kathleen Marchal, Benjamin Steeb, Emre Özdemir, Monica L. Mo, Neil Swainston
المساهمون: [ 1 ] Univ Basel, Biozentrum, Basel, Switzerland [ 2 ] Univ Iceland, Ctr Syst Biol, Reykjavik, Iceland [ 3 ] Univ Iceland, Fac Ind Engn Mech Engn & Comp Sci, Reykjavik, Iceland [ 4 ] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA [ 5 ] USDA ARS, Plant Genet Res Unit, Donald Danforth Plant Sci Ctr, St Louis, MO USA [ 6 ] Tech Univ Carolo Wilhelmina Braunschweig, Inst Bioinformat & Biochem, Braunschweig, Germany [ 7 ] Natl Hlth Res Inst, Div Biostat & Bioinformat, Inst Populat Hlth Sci, Zhunan, Taiwan [ 8 ] Univ Iceland, Inst Sci, IS-107 Reykjavik, Iceland [ 9 ] Katholieke Univ Leuven, Ctr Microbial & Plant Genet, Dept Microbial & Mol Syst, Louvain, Belgium [ 10 ] Ecole Polytech Fed Lausanne, Lab Computat Syst Biotechnol, Swiss Inst Bioinformat, Lausanne, Switzerland [ 11 ] Mt Sinai Sch Med, Dept Infect Dis, New York, NY USA [ 12 ] Univ Wisconsin, Dept Chem & Biol Engn, Madison, WI USA [ 13 ] Univ Iceland, Fac Life & Environm Sci, Reykjavik, Iceland [ 14 ] Tech Univ Dortmund, Dept Biochem & Chem Engn, Dortmund, Germany [ 15 ] Univ Manchester, Sch Comp Sci, Manchester, Lancs, England [ 16 ] Univ Manchester, Manchester Ctr Integrat Syst Biol, Manchester Interdisciplinary Bioctr, Manchester, Lancs, England [ 17 ] Pacific NW Natl Lab, Div Biol Sci, Richland, WA 99352 USA
المصدر: BMC SYSTEMS BIOLOGY
BMC Systems Biology, Vol 5, Iss 1, p 8 (2011)
BMC Systems Biology
Thiele, Ines; Hyduke, Daniel R; Steeb, Benjamin; Fankam, Guy; Allen, Douglas K; Bazzani, Susanna; et al.(2011). A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. BMC Systems Biology, 5(1), 8. doi: http://dx.doi.org/10.1186/1752-0509-5-8. Retrieved from: http://www.escholarship.org/uc/item/5x13s7p5
BMC systems biology 5, 8 (2011). doi:10.1186/1752-0509-5-8مصطلحات موضوعية: Salmonella typhimurium, Databases, Factual, PROTEIN, Human pathogen, Bioinformatics, ANNOTATION, Structural Biology, Cooperative Behavior, lcsh:QH301-705.5, 0303 health sciences, Applied Mathematics, Systems Biology, NETWORKS, Computer Science Applications, Flux balance analysis, Anti-Bacterial Agents, Knowledge base, ESCHERICHIA-COLI, Salmonella enterica, Modeling and Simulation, Metabolic Networks and Pathways, Research Article, Annotation, Systems biology, GENOMES, Computational biology, METABOLISM, Biology, Models, Biological, 03 medical and health sciences, ddc:570, Modelling and Simulation, Humans, RECONSTRUCTION, Genomes, Molecular Biology, 030304 developmental biology, 030306 microbiology, business.industry, Protein, Biology and Life Sciences, biology.organism_classification, Metabolism, Workflow, lcsh:Biology (General), Genes, Bacterial, Cooperative behavior, Reconstruction, Networks, business, Escherichia-Coli, Salmonella typhimurium LT2
وصف الملف: application/pdf
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المؤلفون: Bernhard O. Palsson, Neema Jamshidi, Ines Thiele, Fan Li
المساهمون: Rao, Christopher
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 5, Iss 2, p e1000292 (2009)
PLoS computational biology, vol 5, iss 2مصطلحات موضوعية: Proteome, Bioinformatics, QH301-705.5, Physiological, Immunology, Computational biology, Biology, Models, Biological, Biochemistry, Mathematical Sciences, Feedback, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Modelling methods, Models, Information and Computing Sciences, Genetics, Humans, Biology (General), Phosphorylation, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Feedback, Physiological, 0303 health sciences, Toll-like receptor, Computational Biology/Systems Biology, Ecology, Biochemistry/Theory and Simulation, Toll-Like Receptors, Computational Biology, Receptor signaling, Biological Sciences, Biological, Cell biology, Cell Compartmentation, Computational Biology/Signaling Networks, Computational Theory and Mathematics, Modeling and Simulation, Mediation, Identification (biology), Signal transduction, 030217 neurology & neurosurgery, Signal Transduction, Research Article
وصف الملف: application/pdf
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المؤلفون: Ines Thiele, Bernhard O. Palsson, Juan Nogales
المصدر: BMC Systems Biology
BMC Systems Biology, Vol 2, Iss 1, p 79 (2008)
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: In silico, Systems biology, Knowledge Bases, Genome scale, Metabolic network, Genomics, Computational biology, Pseudomonas putida KT2440, Biology, Genome, Models, Biological, Structural Biology, Modelling and Simulation, Databases, Genetic, Computer Simulation, Anaerobiosis, Molecular Biology, lcsh:QH301-705.5, business.industry, Pseudomonas putida, Applied Mathematics, Polyhydroxyalkanoates, Fatty Acids, Computational Biology, Gene Expression Regulation, Bacterial, biology.organism_classification, Genome-scale reconstruction, Computer Science Applications, Biotechnology, Flux balance analysis, Oxygen, lcsh:Biology (General), Modeling and Simulation, business, Genome, Bacterial, Metabolic Networks and Pathways, Toluene, Research Article
وصف الملف: 1642188 bytes; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98138e5495fb158ca9b9473cb587404
https://pubmed.ncbi.nlm.nih.gov/18793442