المؤلفون: Hubert B. Gaspar, Giuseppa Piras, Karen F. Buckland, Sara Benedetti, Giorgia Santilli, Adrian J. Thrasher, Michael Rothe, Diego Leon-Rico, Michael Ashworth, Narda Theobald, Winston Vetharoy, Elena Armenteros-Monterroso, Uimook Choi, Harry L. Malech, Elizabeth M. Kang, Christine Rivat, Axel Schambach, Andrea Schejtman

المصدر: Human Gene Therapy

مصطلحات موضوعية: Genetic enhancement, CD34, Clinical Developments, chronic granulomatous disease, Granulomatous Disease, Chronic, Viral vector, 03 medical and health sciences, Mice, 0302 clinical medicine, Chronic granulomatous disease, Genetics, Medicine, Animals, Humans, Tissue Distribution, Molecular Biology, biodistribution, Oxazoles, 030304 developmental biology, 0303 health sciences, business.industry, lentiviral gene therapy, genotoxicity, NADPH Oxidases, Genetic Therapy, medicine.disease, Clinical trial, Haematopoiesis, 030220 oncology & carcinogenesis, Immunology, Molecular Medicine, Stem cell, business, Homing (hematopoietic)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2712c884ee0cffcda924177d0007d4e4
http://europepmc.org/articles/PMC8575060

المؤلفون: Adrian J. Thrasher, Simon Clare, Walmir Cutrim Aragão-Filho, Hubert B. Gaspar, Andrea Schejtman, Antonio Condino-Neto, Claire Booth, Giorgia Santilli, Siobhan O. Burns, Maren Weisser, Marta Zinicola, David C. Thomas

المساهمون: Wellcome Trust

المصدر: Gene Therapy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, PROMOTER, Genetic enhancement, VECTOR, Genetic transduction, Research & Experimental Medicine, Biology, Brief Communication, Granulomatous Disease, Chronic, Microbiology, Viral vector, ACTIVATION, Mice, 03 medical and health sciences, 0302 clinical medicine, Chronic granulomatous disease, hemic and lymphatic diseases, Genetics, medicine, Animals, Humans, Oxazoles, Molecular Biology, 11 Medical and Health Sciences, Immunological disorders, Genetics & Heredity, Science & Technology, NADPH oxidase, Haematopoietic stem cells, NADPH Oxidases, Genetic Therapy, 06 Biological Sciences, medicine.disease, Haematopoiesis, 030104 developmental biology, Biotechnology & Applied Microbiology, Medicine, Research & Experimental, LEADS, 030220 oncology & carcinogenesis, Salmonella Infections, Primary immunodeficiency, biology.protein, Molecular Medicine, Stem cell, Life Sciences & Biomedicine, SALMONELOSE ANIMAL, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b7cbb8e68c176b438d2097ce88aeaf
https://doi.org/10.1038/s41434-020-0164-6

المؤلفون: Hamoud Al-Mousa, James Lee, Giorgia Santilli, Kenneth G. C. Smith, Fowzan S. Alkuraya, Eve L. Coomber, Louis-Marie Charbonnier, Hasan Al-Dhekri, Anneliese O. Speak, Simon Clare, Anne E. Beenken, Andrea Schejtman, Elizabeth R. Dufficy, Talal A. Chatila, David C. Thomas, Adrian J. Thrasher

المساهمون: Lee, James [0000-0001-5711-9385], Speak, Anneliese [0000-0003-4890-4685], Smith, Kenneth [0000-0003-3829-4326], Apollo - University of Cambridge Repository

مصطلحات موضوعية: 0301 basic medicine, Male, Phagocyte, Protein subunit, T-Lymphocytes, Immunology, medicine.disease_cause, Granulomatous Disease, Chronic, Lymphohistiocytosis, Hemophagocytic, 03 medical and health sciences, Mice, 0302 clinical medicine, Chronic granulomatous disease, medicine, Immunology and Allergy, Animals, Humans, Cells, Cultured, Bone Marrow Transplantation, Respiratory Burst, chemistry.chemical_classification, Reactive oxygen species, Mutation, Phagocytes, NADPH oxidase, biology, Membrane Proteins, NADPH Oxidases, medicine.disease, Molecular biology, Transmembrane protein, Respiratory burst, Pedigree, 030104 developmental biology, medicine.anatomical_structure, chemistry, Gene Knockdown Techniques, biology.protein, Reactive Oxygen Species, Oxidation-Reduction, 030215 immunology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea18756fea7700da80dce61c8c05c33a

المؤلفون: Francesca Marino-Merlo, Christoph Borner, Antonio Mastino, Emanuela Papaianni, Souhayla El Maadidi, Simon Neumann, Ulrich Maurer, Andrea Schejtman

المصدر: PLoS ONE, Vol 10, Iss 6, p e0126645 (2015)
PloS one (2015). doi:10.1371/journal.pone.0126645
info:cnr-pdr/source/autori:Papaianni E, El Maadidi S, Schejtman A, Neumann S, Maurer U, Marino-Merlo F, Mastino A, Borner C./titolo:Phylogenetically distant viruses use the same BH3-only protein Puma to trigger Bax%2FBak-dependent apoptosis of infected mouse and human cells./doi:10.1371%2Fjournal.pone.0126645/rivista:PloS one/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
PLoS ONE

مصطلحات موضوعية: Fas Ligand Protein, viruses, lcsh:Medicine, Apoptosis, Herpesvirus 1, Human, Virus Replication, Semliki Forest virus, Virus, TNF-Related Apoptosis-Inducing Ligand, Small hairpin RNA, Mice, Bcl-2-associated X protein, Proto-Oncogene Proteins, Puma, Animals, Humans, RNA, Messenger, lcsh:Science, Phylogeny, bcl-2-Associated X Protein, Multidisciplinary, biology, Caspase 3, Tumor Suppressor Proteins, lcsh:R, Cytochromes c, RNA-Binding Proteins, U937 Cells, Fibroblasts, HCT116 Cells, biology.organism_classification, Semliki forest virus, NF-KAPPA-B, Human herpesvirus 1, SEMLIKI-FOREST-VIRUS, BLOCKS APOPTOSIS, GLYCOPROTEIN-D, MITOCHONDRIAL APOPTOSIS, VIRAL-PROTEINS, HOST-DEFENSE, CANCER-CELLS, CELL DEATH, VIRUS REPLICATION, Molecular biology, Cell biology, Enzyme Activation, Nuclear Pore Complex Proteins, bcl-2 Homologous Antagonist-Killer Protein, Viral replication, Receptor-Interacting Protein Serine-Threonine Kinases, biology.protein, lcsh:Q, biological phenomena, cell phenomena, and immunity, Apoptosis Regulatory Proteins, Bcl-2 Homologous Antagonist-Killer Protein, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5feb71b11c40b30a834d15a53da411d8
http://europepmc.org/articles/PMC4452691?pdf=render