المؤلفون: Chiara Nardin, Abraham Tettey-Matey, Viola Donati, Daniela Marazziti, Chiara Di Pietro, Chiara Peres, Marcello Raspa, Francesco Zonta, Guang Yang, Maryna Gorelik, Serena Singh, Lia Cardarelli, Sachdev S. Sidhu, Fabio Mammano

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7337

مصطلحات موضوعية: Ions, bicistronic vectors, Organic Chemistry, cancer, connexins, drug discovery, genetically encoded calcium indicators, genodermatoses, lentivirus, monoclonal antibodies, Biological Transport, Humans, Calcium, Connexins, General Medicine, Catalysis, Computer Science Applications, Inorganic Chemistry, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5357fe6b9784c19af9cc962a5211ba9
https://doi.org/10.3390/ijms23137337

المؤلفون: Viola Donati, Francesco Zonta, Damiano Buratto, Fabio Mammano

المصدر: Biochimica et biophysica acta. Molecular basis of disease 1867 (2021). doi:10.1016/j.bbadis.2020.166047
info:cnr-pdr/source/autori:Buratto, Damiano; Donati, Viola; Zonta, Francesco; Mammano, Fabio/titolo:Harnessing the therapeutic potential of antibodies targeting connexin hemichannels/doi:10.1016%2Fj.bbadis.2020.166047/rivista:Biochimica et biophysica acta. Molecular basis of disease/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:1867

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, medicine.drug_class, Connexin, Monoclonal antibody, Epitope, Antibodies, Connexins, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Agents, Immunological, Neoplasms, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Cancer, Inflammation, biology, Point mutation, Rare diseases, Cell biology, 030104 developmental biology, antibody drug discovery, cancer, inflammation, rare diseases, Membrane protein, Polyclonal antibodies, Connexin 43, biology.protein, Molecular Medicine, Antibody, 030217 neurology & neurosurgery, Function (biology), Antibody drug discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726778a3f76c10e6a1d84af27eef4b2a
https://pubmed.ncbi.nlm.nih.gov/33418036

المؤلفون: Fabio Mammano, Mario Bortolozzi

المصدر: Cell Calcium. 70:117-126

مصطلحات موضوعية: 0301 basic medicine, Physiology, Protein subunit, Lesser epithelial ridge, Morphogenesis, Connexin, Caspase 3, Development, Deafness, Biology, Mouse models, Greater epithelial ridge, Connexins, Inner hair cells, 03 medical and health sciences, otorhinolaryngologic diseases, Ca2+waves, Molecular Biology, Cochlea, Calcium signaling, Peripheral auditory system, Outer hair cells, Autophagy, IP3, Gap junction, Cell Biology, Anatomy, Mitochondria, ATP, 030104 developmental biology, Caspase-3, Peripheral auditory system, Development, Morphogenesis, Caspase-3, Mitochondria, Greater epithelial ridge, Lesser epithelial ridge, Ca2+waves, ATP, IP3, Spiral ganglion neurons, Inner hair cells, Outer hair cells, Connexins, Deafness, Mouse models, Spiral ganglion neurons, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deae7610aea5257740a2f0b6e40d9eed
https://doi.org/10.1016/j.ceca.2017.05.006

المؤلفون: Francesco Zonta, Damiano Buratto, Giulia Crispino, Andrea Carrer, Francesca Bruno, Guang Yang, Fabio Mammano, Sergio Pantano

المصدر: Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in molecular neuroscience 11 (2018): 1–12. doi:10.3389/fnmol.2018.00170
info:cnr-pdr/source/autori:Zonta, Francesco; Buratto, Damiano; Crispino, Giulia; Carrer, Andrea; Bruno, Francesca; Yang, Guang; Mammano, Fabio; Pantano, Sergio/titolo:Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans/doi:10.3389%2Ffnmol.2018.00170/rivista:Frontiers in molecular neuroscience/anno:2018/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume:11
Frontiers in Molecular Neuroscience

مصطلحات موضوعية: 0301 basic medicine, Conformational change, connexin, Connexin, coarse grained simulations, lcsh:RC321-571, Cx26, 03 medical and health sciences, Cellular and Molecular Neuroscience, conformational change, Patch clamp, SIRAH force field, electrophysiology, gap junction hemichannels, Molecular Biology, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, Chemistry, Mutagenesis, Gap junction, Transmembrane domain, Electrophysiology, 030104 developmental biology, Cytoplasm, Biophysics, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4d9364cdd64f2259df4569d729d477
https://www.frontiersin.org/article/10.3389/fnmol.2018.00170/full

المؤلفون: Liang Xu, Andrea Carrer, Francesco Zonta, Zhihu Qu, Peixiang Ma, Sheng Li, Federico Ceriani, Damiano Buratto, Giulia Crispino, Veronica Zorzi, Gaia Ziraldo, Francesca Bruno, Chiara Nardin, Chiara Peres, Flavia Mazzarda, Anna M. Salvatore, Marcello Raspa, Ferdinando Scavizzi, Youjun Chu, Sichun Xie, Xuemei Yang, Jun Liao, Xiao Liu, Wei Wang, Shanshan Wang, Guang Yang, Richard A. Lerner, Fabio Mammano

المصدر: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in molecular neuroscience 10 (2017): 298–317. doi:10.3389/fnmol.2017.00298
info:cnr-pdr/source/autori:Xu, Liang; Carrer, Andrea; Zonta, Francesco; Qu, Zhihu; Ma, Peixiang; Li, Sheng; Ceriani, Federico; Buratto, Damiano; Crispino, Giulia; Zorzi, Veronica; Ziraldo, Gaia; Bruno, Francesca; Nardin, Chiara; Peres, Chiara; Mazzarda, Flavia; Salvatore, Anna M.; Raspa, Marcello; Scavizzi, Ferdinando; Chu, Youjun; Xie, Sichun; Yang, Xuemei; Liao, Jun; Liu, Xiao; Wang, Wei; Wang, Shanshan; Yang, Guang; Lerner, Richard A.; Mammano, Fabio/titolo:Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders/doi:10.3389%2Ffnmol.2017.00298/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:298/pagina_a:317/intervallo_pagine:298–317/volume:10
Frontiers in Molecular Neuroscience

مصطلحات موضوعية: 0301 basic medicine, keratinocytes, Phage display, medicine.drug_class, cochlea, Connexin, antibody library, Biology, Monoclonal antibody, syndromic autosomal hereditary deafness, Connexon, Epitope, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, medicine, otorhinolaryngologic diseases, Molecular Biology, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, antibody structure, connexins, epitope identification, Gap junction, Molecular biology, 3. Good health, Cell biology, 030104 developmental biology, Mechanism of action, biology.protein, sense organs, medicine.symptom, Antibody, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a27789fba693c6c8e6078ef742d88e5
https://eprints.whiterose.ac.uk/122100/1/fnmol-10-00298.pdf

المؤلفون: Fabio Mammano, Ramin Badii, Francesco Zonta, Khalid Abdulhadi, Giulia Crispino, Moza Khalifa Alkowari, Damiano Buratto, Anna Morgan, Giorgia Girotto, Paolo Gasparini

المساهمون: Zonta, Francesco, Girotto, Giorgia, Buratto, Damiano, Crispino, Giulia, Morgan, Anna, Abdulhadi, Khalid, Alkowari, Moza, Badii, Ramin, Gasparini, Paolo, Mammano, Fabio

المصدر: Human Molecular Genetics
Human molecular genetics
24 (2015): 2641–2648. doi:10.1093/hmg/ddv026
info:cnr-pdr/source/autori:Zonta, Francesco; Girotto, Giorgia; Buratto, Damiano; Crispino, Giulia; Morgan, Anna; Abdulhadi, Khalid; Alkowari, Moza; Badii, Ramin; Gasparini, Paolo; Mammano, Fabio/titolo:The p.Cys169Tyr variant of connexin 26 is not a polymorphism/doi:10.1093%2Fhmg%2Fddv026/rivista:Human molecular genetics (Print)/anno:2015/pagina_da:2641/pagina_a:2648/intervallo_pagine:2641–2648/volume:24

مصطلحات موضوعية: Male, Models, Molecular, Genotype, Protein Conformation, Mutation, Missense, Gene Expression, Connexin, connexin 26, Biology, Molecular Dynamics, Transfection, Connexins, Hereditary hearing loss, Cell Line, Protein structure, Mutant protein, deafness, genetic deafness, Gene expression, otorhinolaryngologic diseases, Genetics, Humans, Missense mutation, Protein Interaction Domains and Motifs, Hearing Loss, Molecular Biology, Gene, Alleles, Genetics (clinical), Polymorphism, Genetic, Gap junction, Hereditary hearing lo, Gap Junctions, Articles, General Medicine, Immunohistochemistry, Molecular biology, Pedigree, Connexin 26, Amino Acid Substitution, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf6ff72afb82378f6a7ddd64e6bbe23
https://doi.org/10.1093/hmg/ddv026

المؤلفون: Veronica Zorzi, Fabiola Paciello, Gaia Ziraldo, Chiara Peres, Flavia Mazzarda, Chiara Nardin, Miriam Pasquini, Francesco Chiani, Marcello Raspa, Ferdinando Scavizzi, Andrea Carrer, Giulia Crispino, Catalin D. Ciubotaru, Hannah Monyer, Anna R. Fetoni, Anna M. Salvatore, Fabio Mammano

المساهمون: Zorzi, Veronica, Paciello, Fabiola, Ziraldo, Gaia, Peres, Chiara, Mazzarda, Flavia, Nardin, Chiara, Pasquini, Miriam, Chiani, Francesco, Raspa, Marcello, Scavizzi, Ferdinando, Carrer, Andrea, Crispino, Giulia, Ciubotaru, Catalin D., Monyer, Hannah, Fetoni, Anna R., Salvatore, Anna M., Mammano, Fabio

المصدر: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in molecular neuroscience 10 (2017). doi:10.3389/fnmol.2017.00379
info:cnr-pdr/source/autori:Zorzi, Veronica; Paciello, Fabiola; Ziraldo, Gaia; Peres, Chiara; Mazzarda, Flavia; Nardin, Chiara; Pasquini, Miriam; Chiani, Francesco; Raspa, Marcello; Scavizzi, Ferdinando; Carrer, Andrea; Crispino, Giulia; Ciubotaru, Catalin D.; Monyer, Hannah; Fetoni, Anna R.; Salvatore, Anna M.; Mammano, Fabio/titolo:Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function/doi:10.3389%2Ffnmol.2017.00379/rivista:Frontiers in molecular neuroscience/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Frontiers in Molecular Neuroscience

مصطلحات موضوعية: 0301 basic medicine, Cochlear amplifier, medicine.medical_specialty, cochlea, pannexins, connexins, hair cells, non-sensory cells, auditory brainstem responses, distortion product otoacoustic emissions, hair cells, Settore BIO/09 - FISIOLOGIA, Otoacoustic emission, Connexin, Audiology, Biology, Pannexin, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, cochlea, pannexins, connexins, non-sensory cells, auditory brainstem responses, distortion product otoacoustic emissions, medicine, otorhinolaryngologic diseases, Auditory brainstem responses, Cochlea, Connexins, Distortion product otoacoustic emissions, Hair cells, Non-sensory cells, Pannexins, Molecular Biology, Inner ear, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Original Research, Distortion product otoacoustic emission, Non-sensory cell, Auditory brainstem response, 030104 developmental biology, medicine.anatomical_structure, Organ of Corti, Hair cell, sense organs, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8dcbc7e28b0efdad06efeae315b37c
http://hdl.handle.net/11588/871873

المؤلفون: Saida Ortolano, Andrew Parker, Pietro Scimemi, Giulia Crispino, Marisa Brini, Ernesto Carafoli, Steve D.M. Brown, Francesca Di Leva, Fabio Mammano, Edoardo Arslan, Nicholas J. Parkinson, Mario Bortolozzi, Romolo Daniele De Siati

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, Confocal Microscopy, Endolymph, Stereocilia (inner ear), Deafness, Biochemistry, Mice, Cytosol, PMCA2 Calcium Pump, hereditary deafness, Mechanotransduction, Calcium signaling, Tommy Mouse, Mice, Inbred BALB C, Mice, Inbred C3H, Calcium signalling, Molecular Bases of Disease, Cell biology, Hair Cells, medicine.anatomical_structure, Genetic Diseases, Molecular Sequence Data, Mutation, Missense, chemistry.chemical_element, Biology, Calcium, Fluorescence, Stereocilia, Plasma Membrane Calcium-Transporting ATPases, Hair Cells, Auditory, otorhinolaryngologic diseases, medicine, Animals, Humans, Inner ear, Amino Acid Sequence, Molecular Biology, Ca2+-ATPase, Enzyme Kinetics, Calcium metabolism, Cell Biology, Disease Models, Animal, chemistry, Organ of Corti, Ear, Inner, sense organs, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdf8c64dbcf353e5daf64d60c988c41
https://doi.org/10.1074/jbc.m110.170092

المؤلفون: Klaus Willecke, Romolo Daniele De Siati, Karen P. Steel, Stephan Sonntag, Laura Zúñiga Rodríguez, Fabio Mammano, Mario Bortolozzi, Melanie Schütz, Pietro Scimemi, Anke Seydel, Giulia Crispino, Rosamaria Santarelli, Neil J. Ingham, Paromita Majumder

المصدر: Human Molecular Genetics

مصطلحات موضوعية: Aging, Connexin, COMMUNICATION, Deafness, MOUSE, Connexins, Mice, Adenosine Triphosphate, Gene Knock-In Techniques, Organ of Corti, Genetics (clinical), Recombination, Genetic, XENOPUS OOCYTES, Articles, General Medicine, Anatomy, GAP-JUNCTION HEMICHANNELS, Cochlea, Cell biology, Connexin 26, medicine.anatomical_structure, medicine.symptom, GJB6, Fluorescence Recovery After Photobleaching, Genetically modified mouse, Hearing loss, Immunoblotting, GUINEA-PIG COCHLEA, Biology, Permeability, Hearing Loss, Bilateral, Gene knockin, GAP-JUNCTION HEMICHANNELS, MAMMALIAN INNER-EAR, GUINEA-PIG COCHLEA, ATP RELEASE, STRIA VASCULARIS, XENOPUS OOCYTES, HELA-CELLS, MOUSE, COMMUNICATION, PERMEABILITY, Connexin 30, Evoked Potentials, Auditory, Brain Stem, otorhinolaryngologic diseases, Genetics, medicine, Animals, Humans, Inner ear, Calcium Signaling, Molecular Biology, HELA-CELLS, STRIA VASCULARIS, MAMMALIAN INNER-EAR, ATP RELEASE, Mutation, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3bbd14c405d4c3d13b587f4ee97117
https://doi.org/10.1093/hmg/ddq402

المؤلفون: John A. Chiorini, Giovanni Di Pasquale, Fabio Anselmi, Giulia Crispino, Fabio Mammano, Saida Ortolano

المصدر: Proceedings of the National Academy of Sciences. 105:18776-18781

مصطلحات موضوعية: Recombinant Fusion Proteins, cochlea, adeno-associated virus, gap junctions, GENE TRANSFER, Repressor, Cre recombinase, Connexin, Deafness, Biology, Connexins, Tissue Culture Techniques, Mice, Gene expression, Connexin 30, otorhinolaryngologic diseases, Animals, Humans, Protein Isoforms, Calcium Signaling, Cochlea, Mice, Knockout, Multidisciplinary, NF-kappa B, Gap junction, Biological Sciences, NFKB1, Molecular biology, Connexin 26, Ear, Inner, biology.protein, Calcium, Cattle, GJB6

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ae8954fc1f881fa3cf5c8e63426195
https://doi.org/10.1073/pnas.0800831105