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المؤلفون: Shohta Mizuno, Takashi Nishiyama, Mai Endo, Koharu Sakoguchi, Takaki Yoshiura, Hana Bessho, Toshio Motoyashiki, Noriyuki Hatae, Tominari Choshi
المصدر: Molecules; Volume 28; Issue 10; Pages: 4059
مصطلحات موضوعية: Chemistry (miscellaneous), Organic Chemistry, Drug Discovery, Molecular Medicine, Pharmaceutical Science, acuminatine, 22-hydroxyacuminatine, benz[6,7]indolizino[1,2-b]quinolin-11(13H)-one, total synthesis, thermal cyclization, Physical and Theoretical Chemistry, Analytical Chemistry
وصف الملف: application/pdf
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المؤلفون: Satoshi Hibino, Makiko Nakaya, Noriyuki Hatae, Mitsunari Nakajima, Satoshi Okuyama, Yuhzo Hieda, Atsushi Sawamoto, Tominari Choshi, Mizuki Yamaoka, Yoshiko Furukawa
المصدر: Molecules
Volume 24
Issue 7
Molecules, Vol 24, Iss 7, p 1366 (2019)مصطلحات موضوعية: Programmed cell death, neurite outgrowth, Neurite, Cell Survival, Neuronal Outgrowth, Carbazoles, Pharmaceutical Science, medicine.disease_cause, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, lcsh:Organic chemistry, carbazole, Drug Discovery, medicine, Animals, Physical and Theoretical Chemistry, Hydrogen peroxide, Cytotoxicity, PI3K/AKT/mTOR pathway, Neurons, biology, Molecular Structure, 010405 organic chemistry, Akt/PKB signaling pathway, anti-oxidant, Organic Chemistry, Cell Differentiation, Hydrogen Peroxide, neuronal death, neuro2a cells, 0104 chemical sciences, Cell biology, chemistry, Chemistry (miscellaneous), biology.protein, Molecular Medicine, 030217 neurology & neurosurgery, Oxidative stress, Neurotrophin, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Junzo Hirose, Satoshi Hibino, Hisao Tomida, Noriyuki Hatae, Osamu Hori, Haruto Fujioka, Makoto Anraku, Tominari Choshi, Yuhzo Hieda
المصدر: Bioorganic & Medicinal Chemistry Letters. 24:3530-3533
مصطلحات موضوعية: Antioxidant, ABTS, Molecular Structure, Chemistry, Carbazole, medicine.medical_treatment, Organic Chemistry, Clinical Biochemistry, Carbazoles, Pharmaceutical Science, Formyl group, Biochemistry, Antioxidants, chemistry.chemical_compound, Carazostatin, Alkaloids, Drug Discovery, medicine, Molecular Medicine, Organic chemistry, Molecular Biology
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المؤلفون: Tetsuo Okujima, Hidemitsu Uno, Satoshi Hibino, Hiroko Yamada, Noriyuki Hatae, Jun Nakamura, Tominari Choshi, Eiko Toyota, Chiaki Okada, Minoru Ishikura, Takumi Abe
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:4637-4640
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, HL-60 Cells, Tumor cells, Biochemistry, Inhibitory Concentration 50, Immune system, Neoplasms, Drug Discovery, medicine, Humans, Moiety, Molecular Biology, Antitumor activity, Molecular Structure, Chemistry, Organic Chemistry, Phenanthrenes, HCT116 Cells, medicine.disease, Human tumor, Leukemia, Cell culture, Cancer research, Molecular Medicine
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المؤلفون: Dai Watanabe, Haruhisa Inoue, Tatsushi Toda, Takayuki Kondo, Satoko Yamawaki, Tatsutoshi Nakahata, Shu-ichi Ueno, Kei Maruyama, Hiroyuki Hioki, Motoko Naitoh, Tsuneyoshi Seki, Takeshi Kaneko, Yutaka Ohsawa, Shinya Yamanaka, Isao Asaka, Takashi Asada, William L. Klein, Kayoko Tsukita, Naoki Yahata, Osamu Hori, Keiko Imamura, Keisuke Okita, Akira Watanabe, Masashi Asai, Kazuhiro Kobayashi, Katsuhiro Yoshikawa, Ryuji Hata, Kazuma Murakami, Shigehiko Suzuki, Yumiko Kutoku, Rie Nakano, Kazuhiro Irie, Kazutoshi Takahashi, Ryosuke Takahashi, Tominari Choshi, Kaori Watanabe, Hiroshi Mori, Naohiro Egawa, Yoshihide Sunada, Satoshi Hibino, Nobuhisa Iwata, Chie Kadoya, Takashi Aoi
المصدر: Cell Stem Cell. 12(4):487-496
مصطلحات موضوعية: Docosahexaenoic Acids, Induced Pluripotent Stem Cells, Intracellular Space, Biology, medicine.disease_cause, Models, Biological, Pathogenesis, Alzheimer Disease, medicine, Amyloid precursor protein, Genetics, Humans, Induced pluripotent stem cell, Protein Structure, Quaternary, Cerebral Cortex, Neurons, Mutation, Amyloid beta-Peptides, Endoplasmic reticulum, Cell Differentiation, Cell Biology, Oxidative Stress, Phenotype, Cancer research, Unfolded protein response, biology.protein, Molecular Medicine, Mutant Proteins, Intracellular, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Katsura Takano, Satoshi Ogawa, Yasuko Kitao, Hiroto Suzuki, Hikari Miura, Satoshi Hibino, Osamu Hori, Tominari Choshi, Rika Murakami, Masashi Yamada
المصدر: Journal of Pharmacological Sciences, Vol 108, Iss 2, Pp 164-171 (2008)
مصطلحات موضوعية: Embryonal Carcinoma Stem Cells, Thapsigargin, Recombinant Fusion Proteins, Carbazoles, Biology, Endoplasmic Reticulum, medicine.disease_cause, PC12 Cells, chemistry.chemical_compound, Stress, Physiological, medicine, Animals, Homeostasis, Humans, Buthionine sulfoximine, Buthionine Sulfoximine, Pharmacology, Cell Death, Dose-Response Relationship, Drug, Tunicamycin, Endoplasmic reticulum, lcsh:RM1-950, Glutathione, Rats, Cell biology, Oxidative Stress, lcsh:Therapeutics. Pharmacology, chemistry, Cytoprotection, Unfolded protein response, Molecular Medicine, Calcium, Intracellular, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c961fb2281b64329077f821731d697e2
https://doi.org/10.1254/jphs.08136fp -
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المؤلفون: Noriyuki Hatae, Yuhki Kurata, Satoshi Hibino, Chiaki Okada, Takashi Nishiyama, Sayumi Shimoyama, Yuhsuke Ishihara, Erina Fujita, Tominari Choshi, Saori Shigenobu
المصدر: Bioorganicmedicinal chemistry letters. 25(14)
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, HL-60 Cells, Ring (chemistry), complex mixtures, Biochemistry, chemistry.chemical_compound, Alkaloids, Drug Discovery, Cytotoxic T cell, Humans, heterocyclic compounds, Molecular Biology, Cell Proliferation, Benzophenanthridines, Phenanthridine, biology, organic chemicals, Topoisomerase, Organic Chemistry, Cationic polymerization, Iminium, HCT116 Cells, Phenanthridines, Chelerythrine, DNA Topoisomerases, Type II, chemistry, DNA Topoisomerases, Type I, Cancer cell, biology.protein, Molecular Medicine
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المؤلفون: Kohji Matsumoto, Tominari Choshi, Mai Hourai, Kenji Sasaki, Minoru Ishikura, Yoshito Zamami, Shigeo Tohyama, Tatsunori Iwamura, Takumi Abe, Noriyuki Hatae, Satoshi Hibino, Junko Nobuhiro
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4762-4764
مصطلحات موضوعية: chemistry.chemical_classification, Calothrixin B, Alkylation, Molecular Structure, biology, Stereochemistry, Plasmodium falciparum, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, biology.organism_classification, Biochemistry, In vitro, Indole Alkaloids, Antimalarials, Structure-Activity Relationship, chemistry, parasitic diseases, Drug Discovery, Molecular Medicine, Structure–activity relationship, Molecular Biology, Alkyl
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