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1
المؤلفون: Pei-Fen Yao, Jie-Bin Ou, Du-Chao Zhou, Honggen Wang, Zhi-Shu Huang, Hua-Ting Xie, Cheng-Cheng Liang, Shi-Liang Huang, Shuo-Bin Chen, Yan-Wen Mai
المصدر: Bioorganic chemistry. 114
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Bioassay, Potency, Humans, Topoisomerase II Inhibitors, Cytotoxicity, Poly-ADP-Ribose Binding Proteins, Molecular Biology, IC50, Etoposide, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Topoisomerase, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, DNA Topoisomerases, Type II, Cell culture, biology.protein, Drug Screening Assays, Antitumor, medicine.drug
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2
المؤلفون: Yao-Hao Xu, Zhi-Shu Huang, Tian-Miao Ou, Zhao Xu, Qingjiang Li, Hong Yu, Yong Rao, Shi-Liang Huang, Bing-Bing Song, Chan Li, Guo-Ping Zhong, Qin-Qin Song, Honggen Wang, Jia-Heng Tan, Shuo-Bin Chen, Yu-Tao Hu, Ji-Ming Ye
المصدر: European journal of medicinal chemistry. 192
مصطلحات موضوعية: Male, Cell, Pharmacology, Diet, High-Fat, 01 natural sciences, 03 medical and health sciences, Mice, Structure-Activity Relationship, Metabolic Diseases, 3T3-L1 Cells, Drug Discovery, medicine, Animals, Obesity, Protein kinase A, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Metabolic disorder, AMPK, Cell Differentiation, General Medicine, medicine.disease, 0104 chemical sciences, Mice, Inbred C57BL, medicine.anatomical_structure, Cholesterol, Mitochondrial biogenesis, Toxicity, Microsome, Anti-Obesity Agents
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3
المؤلفون: Pei-Fen Yao, Shi-Liang Huang, Chen Zhang, Yu-Ting Lu, Zhi-Shu Huang, Yan-Wen Mai, Du-Chao Zhou, Jie Xia, Honggen Wang
المصدر: Bioorganic chemistry. 91
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, HeLa, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Humans, Topoisomerase II Inhibitors, Binding site, Cytotoxicity, Molecular Biology, Cell Proliferation, Binding Sites, biology, Molecular Structure, 010405 organic chemistry, Topoisomerase, Aryl, Organic Chemistry, Quinones, Cell cycle, biology.organism_classification, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, DNA Topoisomerases, Type II, chemistry, Cell culture, Drug Design, biology.protein, Quinazolines, Drug Screening Assays, Antitumor, Protein Binding
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4
المؤلفون: Lian-Quan Gu, Lin-Kun An, Jia-Heng Tan, Zhi-Shu Huang, Jin-Hui He, Hui-Yun Liu, Shi-Liang Huang, Ding Li, Tian-Miao Ou, Zeng Li
المصدر: European Journal of Medicinal Chemistry. 63:1-13
مصطلحات موضوعية: Cell Survival, Stereochemistry, HL-60 Cells, Ligands, G-quadruplex, Binding, Competitive, chemistry.chemical_compound, Drug Discovery, Humans, Phenyl group, Molecule, Benzamide, Telomerase, Cellular Senescence, Telomere Shortening, Pharmacology, Molecular Structure, Phenol, Hydrogen bond, Circular Dichroism, Organic Chemistry, DNA, General Medicine, Surface Plasmon Resonance, Telomere, G-Quadruplexes, Kinetics, chemistry, Intramolecular force, Quinazolines, Selectivity
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5
المؤلفون: Zhi-Shu Huang, Ding Li, Yan-Ping Li, Yan He, Wen Luo, Lian-Quan Gu, Shi-Liang Huang
المصدر: European Journal of Medicinal Chemistry. 46:2609-2616
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Crystallography, X-Ray, Chemical synthesis, Antioxidants, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Drug Discovery, medicine, Humans, Structure–activity relationship, Butyrylcholinesterase, Cholinesterase, Pharmacology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Active site, Stereoisomerism, General Medicine, Acetylcholinesterase, Peptide Fragments, chemistry, Enzyme inhibitor, Tacrine, biology.protein, Cholinesterase Inhibitors, medicine.drug
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6
المؤلفون: Lian-Quan Gu, Zhi-Shu Huang, Jia-Heng Tan, Tian-Miao Ou, Jin-Qiang Hou, Shi-Liang Huang, Yan Ma
المصدر: European Journal of Medicinal Chemistry. 46:1906-1913
مصطلحات موضوعية: Models, Molecular, Berberine, Transcription, Genetic, Stereochemistry, Guanine, HL60, Down-Regulation, Antineoplastic Agents, HL-60 Cells, Ligands, G-quadruplex, Proto-Oncogene Proteins c-myc, chemistry.chemical_compound, Drug Discovery, Humans, heterocyclic compounds, Cells, Cultured, Cell Proliferation, Pharmacology, Molecular Structure, Reverse Transcriptase Polymerase Chain Reaction, Cell growth, Ligand, Alkaloid, Organic Chemistry, Stereoisomerism, DNA, General Medicine, Isoquinolines, G-Quadruplexes, chemistry, Biochemistry, Quinolines, Thermodynamics, Drug Screening Assays, Antitumor
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7
المؤلفون: Shi-Liang Huang, Fang-Xian Ning, Ding Li, Zhi-Shu Huang, Yong-Cheng Li, Min-Hua Nie, Lian-Quan Gu, Jia-Heng Tan, Yan-Ping Li, Tian-Miao Ou, Meng-Bi Yang
المصدر: European Journal of Medicinal Chemistry. 46:1572-1581
مصطلحات موضوعية: Models, Molecular, Tertiary amine, Cell Survival, Amyloid beta, Stereochemistry, Crystallography, X-Ray, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Tumor Cells, Cultured, Humans, Structure–activity relationship, Methiodide, Butyrylcholinesterase, Pharmacology, Amyloid beta-Peptides, Molecular Structure, biology, Chemistry, Organic Chemistry, Stereoisomerism, General Medicine, Acetylcholinesterase, Peptide Fragments, Enzyme inhibitor, biology.protein, Cholinesterase Inhibitors
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8
المؤلفون: Jia-Heng Tan, Yan-Wen Mai, Bing-Lei Yao, Ding Li, Pei-Fen Yao, Shuo-Bin Chen, Zhi-Shu Huang, Tian-Miao Ou, Hua-Ting Xie, Shi-Liang Huang, Lian-Quan Gu, Honggen Wang
المصدر: European journal of medicinal chemistry. 92
مصطلحات موضوعية: Stereochemistry, HL-60 Cells, Cleavage (embryo), HeLa, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Humans, Topoisomerase II Inhibitors, Amines, Cytotoxicity, Biological evaluation, Cell Proliferation, Pharmacology, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Topoisomerase, Organic Chemistry, General Medicine, biology.organism_classification, DNA Topoisomerases, Type II, Design synthesis, DNA Topoisomerases, Type I, Cell culture, Drug Design, biology.protein, Phenazines, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, K562 Cells, Human cancer, HeLa Cells
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9
المؤلفون: Jia-Heng Tan, Shi-Liang Huang, Tian-Miao Ou, Ding Li, Zhi-Shu Huang, Peng Zhai, Chun-Li Xia, Lian-Quan Gu
المصدر: Current Alzheimer research. 12(5)
مصطلحات موضوعية: Amyloid, Curcumin, Oxygen radical absorbance capacity, Metal ions in aqueous solution, Antioxidants, chemistry.chemical_compound, Protein Aggregates, Structure-Activity Relationship, Microscopy, Electron, Transmission, Aβ protein, Alzheimer Disease, Cell Line, Tumor, Molecule, Structure–activity relationship, Humans, Chelation, Chromans, Chelating Agents, Amyloid beta-Peptides, Molecular Structure, Chemistry, Spectrum Analysis, Combinatorial chemistry, Peptide Fragments, Oxygen, Neuroprotective Agents, Neurology, Biochemistry, Drug Evaluation, Neurology (clinical), Trolox, Copper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db99582dccbd41df763a31972dbcc31c
https://pubmed.ncbi.nlm.nih.gov/25938868 -
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المؤلفون: Ding Li, Shuo-Bin Chen, Lian-Quan Gu, Zhi-Shu Huang, Yan He, Pei-Fen Yao, Jia-Heng Tan, Shi-Liang Huang, Zhi-Hong Huang
المصدر: European journal of medicinal chemistry. 63
مصطلحات موضوعية: Models, Molecular, Molecular model, Aché, Cell Survival, Antioxidants, Indole Alkaloids, chemistry.chemical_compound, Inhibitory Concentration 50, Alzheimer Disease, Cell Line, Tumor, Drug Discovery, Humans, Cytotoxicity, Butyrylcholinesterase, Chelating Agents, Pharmacology, Amyloid beta-Peptides, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Active site, General Medicine, Acetylcholinesterase, language.human_language, Peptide Fragments, Protein Structure, Tertiary, Kinetics, Biochemistry, Models, Chemical, biology.protein, language, Curcumin, Biocatalysis, Quinazolines, Trolox, Cholinesterase Inhibitors, Protein Binding