المؤلفون: Burillo-Sanz, Sergio, Montes-Cano, M. A., García-Lozano, J. R., Olivas-Martínez, I., Ortego-Centeno, Norberto, García-Hernández, Francisco-José, Espinosa, G., Graña-Gil, G., Sánchez-Bursón, J., Juliá, M. R., Solans, Rosa, Blanco, R., Barnosi-Marín, A. C., Gómez de la Torre, R., Fanlo, P., Rodríguez-Carballeira, M., Rodriguez-Rodriguez, Luis, Camps i Miró, Teresa, Castañeda, Santos, Alegre-Sancho, Juan José, Martín, J., González-Escribano, M. F., Universitat Autònoma de Barcelona

المساهمون: Instituto de Salud Carlos III, Junta de Andalucía, European Commission, Burillo Sanz, Sergio, Blanco, Ricardo, Martín, J., Burillo Sanz, Sergio [0000-0002-6895-7875], Blanco, Ricardo [0000-0003-2344-2285], Martín, J. [0000-0002-2202-0622]

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
SCIENTIFIC REPORTS
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Scientific Reports
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Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)

مصطلحات موضوعية: Male, 0301 basic medicine, humanos, lcsh:Medicine, ComputingMilieux_LEGALASPECTSOFCOMPUTING, Disease, Behcet's disease, Cohort Studies, 0302 clinical medicine, Polymorphism (computer science), mediadores de la inflamación, Genotype, lcsh:Science, estudios de cohortes, Genetics, péptidos y proteínas de señalización intracelular, Multidisciplinary, Behcet Syndrome, Intracellular Signaling Peptides and Proteins, antígenos HLA-B, adulto, MEFV, proteínas citoesqueléticas, Receptors, Tumor Necrosis Factor, Type I, Female, Inflammation Mediators, Adult, Human leukocyte antigen, Biology, Article, 03 medical and health sciences, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, Genetic Predisposition to Disease, síndrome de Behçet, Adaptor Proteins, Signal Transducing, enfermedades autoinflamatorias hereditarias, Polymorphism, Genetic, lcsh:R, Hereditary Autoinflammatory Diseases, predisposición genética a la enfermedad, Epistasis, Genetic, Pyrin, medicine.disease, Minor allele frequency, Cytoskeletal Proteins, 030104 developmental biology, HLA-B Antigens, Epistasis, lcsh:Q, genotipo, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d111baa9d930f566313a800858bc3c12
http://hdl.handle.net/10261/193804

المؤلفون: Xiol C, Vidal S, Pascual-Alonso A, Blasco L, Brandi N, Pacheco P, Gerotina E, O'Callaghan M, Pineda M, Armstrong J, Aguirre F, Aleu M, Alonso X, Alsius M, Amoros M, Antinolo G, Aquino L, Arellano C, Arriola G, Arteaga R, Baena N, Barcos M, Belzunces N, Boronat S, Camacho T, Campistol J, del Campo M, Campo A, Cancho R, Candau R, Canos I, Carrascosa M, Carratala-Marco F, Casano J, Castro P, Cobo A, Colomer J, Conejo D, Corrales M, Cortes R, Cruz G, Csanyi G, de Santos M, de Toledo M, Del Campo M, Del Toro M, Domingo R, Duat A, Duque R, Esparza A, Fernandez R, Fons M, Fontalba A, Galan E, Gallano P, Gamundi M, Garcia P, Garcia M, Garcia-Barcina M, Garcia-Catalan M, Garcia-Cazorla A, Garcia-Minaur S, Garcia-Penas J, Garcia-Silva M, Gassio R, Gean E, Gil B, Gokben S, Gonzalez L, Gonzalez V, Gonzalez J, Gonzalez G, Guillen E, Guitart M, Guitet M, Gutierrez J, Gutierrez E, Herranz J, Iglesias G, Karacic I, Lahoz C, Lao J, Lapunzina P, Lautre-Ecenarro M, Lluch M, Lopez L, Lopez-Ariztegui A, Macaya A, Marin R, Marquez C, Martin E, Martinez B, Martinez-Salcedo E, Mas M, Mateo G, Mendez P, Jimenez A, Moreno S, Mulas F, Narbona J, Nascimento A, Nieto M, Nunes T, Nunez N, Obon M, Onsurbe I, Ortez C, Orts E, Martinez F, Parrilla R, Pascual S, Patino A, Perez-Poyato M, Perez-Duenas B, Poo P, Puche E, Ramos F, Raspall M, Roche A, Roldan S, Rosell J, Ruiz C, Ruiz-Falco M, Russi M, Samarra J, San Antonio V, Sanchez I, Sanmartin X, Sans A, Santacana A, Scholl-Burgi S, Serrano N, Serrano M, Martin-Tamayo P, Tendero A, Torrents J, Tortosa D, Trivino E, Troncoso L, Turon E, Vazquez P, Vazquez C, Velazquez R, Ventura C, Verdu A, Vernet A, Vila M, Villar C, Rett Working Grp

المساهمون: Ege Üniversitesi, [Xiol C, Vidal S, Pascual-Alonso A, Blasco L, Pacheco P] Molecular and Genetics Medicine Section, Hospital Sant Joan de Déu, Barcelona, Spain. [Brandi N] Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Zaguán. Repositorio Digital de la Universidad de Zaragoza
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Scientific Reports
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
SCIENTIFIC REPORTS
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Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
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Consejo Superior de Investigaciones Científicas (CSIC)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)

مصطلحات موضوعية: 0301 basic medicine, alelos, Methyl-CpG-Binding Protein 2, Rett, Síndrome de, humanos, lcsh:Medicine, medicine.disease_cause, 0302 clinical medicine, Genes, X-Linked, X Chromosome Inactivation, Genetic Phenomena::Gene Expression Regulation::Epigenesis, Genetic::Dosage Compensation, Genetic::X Chromosome Inactivation [PHENOMENA AND PROCESSES], Genotype, enfermedades y anomalías neonatales congénitas y hereditarias::enfermedades genéticas congénitas::enfermedades y anomalías neonatales congénitas y hereditarias::enfermedades genéticas congénitas::trastornos heredodegenerativos del sistema nervioso::retraso mental ligado al cromosoma X::síndrome de Rett [ENFERMEDADES], lcsh:Science, genes, X chromosome, Genetics, Mutation, Multidisciplinary, Molecular medicine, Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Heredodegenerative Disorders, Nervous System::Mental Retardation, X-Linked::Rett Syndrome [DISEASES], Brain, Phenotype, estudios de asociación genética, fenotipo, Female, Sequence Analysis, encéfalo, inactivación del cromosoma X, análisis de secuencias, congenital, hereditary, and neonatal diseases and abnormalities, fenómenos genéticos::regulación de la expresión génica::epigénesis genética::compensación de dosis genética::inactivación del cromosoma X [FENÓMENOS Y PROCESOS], Rett syndrome, Biology, X-inactivation, Article, MECP2, Cromosoma X, 03 medical and health sciences, medicine, Rett Syndrome, Humans, Genetic Predisposition to Disease, Allele, mutación, Amino Acids, Peptides, and Proteins::Proteins::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Chromosomal Proteins, Non-Histone::Amino Acids, Peptides, and Proteins::Proteins::Methyl-CpG-Binding Protein 2 [CHEMICALS AND DRUGS], Alleles, Genetic Association Studies, proteína 2 de unión a metil-CpG, lcsh:R, predisposición genética a la enfermedad, Sequence Analysis, DNA, medicine.disease, 030104 developmental biology, aminoácidos, péptidos y proteínas::proteínas::aminoácidos, péptidos y proteínas::proteínas::aminoácidos, péptidos y proteínas::proteínas::nucleoproteínas::proteínas cromosómicas no histona::proteína 2 de unión a metil-CpG [COMPUESTOS QUÍMICOS Y DROGAS], lcsh:Q, síndrome de Rett, genotipo, Transcripció genètica - Regulació, 030217 neurology & neurosurgery

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a9ab94d2dcf8ad628e2e076112113f
http://zaguan.unizar.es/record/86210

المؤلفون: Burillo-Sanz, Sergio, Montes-Cano, Marco-Antonio, García-Lozano, José-Raúl, Ortiz-Fernández, Lourdes, Ortego-Centeno, Norberto, García-Hernández, Francisco-José, Espinosa, Gerard, Graña-Gil, Genaro, Sánchez-Bursón, Juan, Juliá, María Rosa, Solans, Roser, Blanco, Ricardo, Barnosi-Marín, Ana-Celia, Gómez De la Torre, Ricardo, Fanlo, Patricia, Rodríguez-Carballeira, Mónica, Rodriguez-Rodriguez, Luis, Camps, Teresa, Castañeda, Santos, Alegre-Sancho, Juan José, Martín, Javier, González-Escribano, María Francisca, Universitat Autònoma de Barcelona

المساهمون: Instituto de Salud Carlos III, European Commission, Junta de Andalucía, Universitat de Barcelona

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Digital.CSIC. Repositorio Institucional del CSIC
instname
SCIENTIFIC REPORTS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Dipòsit Digital de la UB
Universidad de Barcelona
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Recercat. Dipósit de la Recerca de Catalunya
r-FISABIO. Repositorio Institucional de Producción Científica

مصطلحات موضوعية: 0301 basic medicine, Male, Adenosine Deaminase, Inflammasomes, humanos, Nod2 Signaling Adaptor Protein, Disease, medicine.disease_cause, 0302 clinical medicine, NOD2, péptidos y proteínas de señalización intercelular, inflamasomas, Genetics, Mutation, Multidisciplinary, Behçet's disease, Behcet Syndrome, High-Throughput Nucleotide Sequencing, MEFV, proteína adaptadora de señalización NOD2, Phosphotransferases (Alcohol Group Acceptor), proteínas citoesqueléticas, Receptors, Tumor Necrosis Factor, Type I, Medicine, adenosina desaminasa, Intercellular Signaling Peptides and Proteins, Female, Vasculitis, Malaltia de Behçet, Science, Human leukocyte antigen, Biology, DNA sequencing, Article, 03 medical and health sciences, secuenciación de nucleótidos de alto rendimiento, inflamación, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, Genetic Predisposition to Disease, 1000 Genomes Project, Gene, síndrome de Behçet, mutación, Adaptor Proteins, Signal Transducing, 030203 arthritis & rheumatology, Inflammation, fosfotransferasas (grupo alcohol aceptor), predisposición genética a la enfermedad, Pyrin, Cytoskeletal Proteins, 030104 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b695f1afd07276e7bad5178d155d76
https://ddd.uab.cat/record/253957

المؤلفون: Ortiz-Fernández, Lourdes, Carmona, F. David, Montes-Cano, Marco-Antonio, García-Lozano, José-Raúl, Conde-Jaldón, Marta, Ortego-Centeno, Norberto, Castillo, María Jesús, Espinosa, Gerard, Graña, Jenaro, Sánchez-Bursón, Juan, Juliá, María Rosa, Solans, Roser, Blanco, Ricardo, Barnosi-Marín, Ana-Celia, Gómez de la Torre, Ricardo, Fanlo, Patricia, Rodríguez-Carballeira, Mónica, Rodriguez-Rodriguez, Luis, Camps i Miró, Teresa, Castañeda, Santos, Alegre-Sancho, Juan José, Martín, Javier, González-Escribano, María Francisca, Universitat Autònoma de Barcelona

المساهمون: [Ortiz-Fernandez, Lourdes] Hosp Univ Virgen Rocio IBiS CSIC US, Dept Immunol, Seville 41013, Spain, [Montes-Cano, Marco-Antonio] Hosp Univ Virgen Rocio IBiS CSIC US, Dept Immunol, Seville 41013, Spain, [Garcia-Lozano, Jose-Raul] Hosp Univ Virgen Rocio IBiS CSIC US, Dept Immunol, Seville 41013, Spain, [Conde-Jaldon, Marta] Hosp Univ Virgen Rocio IBiS CSIC US, Dept Immunol, Seville 41013, Spain, [Francisca Gonzalez-Escribano, Maria] Hosp Univ Virgen Rocio IBiS CSIC US, Dept Immunol, Seville 41013, Spain, [Carmona, Francisco-David] PTS Granada, CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada 18016, Spain, [Martin, Javier] PTS Granada, CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada 18016, Spain, [Ortego-Centeno, Norberto] Hosp Clin San Cecilio, Dept Internal Med, Granada 18003, Spain, [Jesus Castillo, Maria] Hosp Univ Virgen Rocio, Dept Internal Med, Seville 41003, Spain, [Espinosa, Gerard] Hosp Univ Clin, Dept Autoimmune Dis, Barcelona 08036, Spain, [Grana-Gil, Genaro] Dept Rheumatol, Complejo Hosp Univ A Coruna, La Coruna 15006, Spain, [Sanchez-Burson, Juan] Hosp Univ Valme, Dept Rheumatol, Seville 41014, Spain, [Rosa Julia, Maria] Hosp Univ Son Espases, Dept Immunol, Palma de Mallorca 07120, Spain, [Solans, Roser] Univ Autonoma Barcelona, Hosp Vall Hebron, Autoimmune Syst Dis Unit, Dept Internal Med, Barcelona 08035, Spain, [Blanco, Ricardo] Hosp Univ Marques Valdecilla, Dept Rheumatol, Santander 39008, Spain, [Barnosi-Marin, Ana-Celia] Dept Internal Med, Complejo Hosp Torrecardenas, Almeria 04009, Spain, [Gomez de la Torre, Ricardo] Hosp Univ Cent Asturias, Dept Internal Med, Asturias 33011, Spain, [Fanlo, Patricia] Hosp Virgen Camino, Dept Internal Med, Pamplona 31008, Spain, [Rodriguez-Carballeira, Monica] Hosp Univ Mutua Terrassa, Dept Internal Med, Terrassa 08221, Spain, [Rodriguez-Rodriguez, Luis] Hosp Clin San Carlos, Dept Rheumatol, Madrid 28040, Spain, [Camps, Teresa] Hosp Reg Univ Malaga, Dept Internal Med, Malaga 29010, Spain, [Castaneda, Santos] IIS Princesa, Hosp Princesa, Dept Rheumatol, Madrid 28006, Spain, [Alegre-Sancho, Juan-Jose] Hosp Univ Doctor Peset, Dept Rheumatol, Valencia 46017, Spain, Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III (ISCIII), Fondos FEDER, Plan Andaluz de Investigacion, ISCIII, RETICS Program (RIER, ISCIII), Instituto de Salud Carlos III, Junta de Andalucía, Red de Investigación en Inflamación y Enfermedades Reumáticas (España), [Ortiz-Fernández,L, Montes-Cano,MA, García-Lozano,JR, Conde-Jaldón,M, González-Escribano,MF] Department of Immunology, Hospital Universitario Virgen del Rocío (IBiS, CSIC, US), Sevilla, Spain. [Carmona,FD, Martín,J] Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, Granada, Spain. [Ortego-Centeno,N] Department of Internal Medicine, Hospital Clínico San Cecilio, Granada, Spain. [Castillo,MJ] Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Sevilla, Spain. [Espinosa,G] Department Autoimmune Diseases, Hospital Universitari Clínic, Barcelona, Spain. [Graña-Gil,G] Department of Rheumatology, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain. [Sánchez-Bursón,J] Department of Rheumatology, Hospital Universitario de Valme, Sevilla, Spain. [Juliá,MR] Department of Immunology, Hospital Universitari Son Espases, Palma de Mallorca, Spain. [Solans,R] Department of Internal Medicine, Autoimmune Systemic Diseases Unit, Hospital Vall d’Hebron, Universidad Autonoma de Barcelona, Barcelona, Spain. [Blanco,R] Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain. [Barnosi-Marín,AC] Department of Internal Medicine, Complejo Hospitalario Torrecárdenas, Almería, Spain. [Gómez de la Torre,R] Department of Internal Medicine, Hospital Universitario Central de Asturias, Asturias, Spain. [Fanlo,P] Department of Internal Medicine, Hospital Virgen del Camino, Pamplona, Spain. [Rodríguez-Carballeira,M] Deparment of Internal Medicine, Hospital Universitari Mútua Terrassa, Terrassa, Spain. [Rodríguez-Rodríguez,L] Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain. [Camps,T] Department of Internal Medicine, Hospital Regional Universitario de Málaga, Málaga, Spain. [Castañeda,S] Department of Rheumatology, Hospital de la Princesa, IIS-Princesa, Madrid, Spain. [Alegre-Sancho,JJ] Department of Rheumatology, Hospital Universitario Doctor Peset, Valencia, Spain., This work was supported by Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III (ISCIII, 13/01118), Fondos FEDER and Plan Andaluz de Investigación (CTS-0197). LOF is the recipient of a fellowship (ISCIII, FI11/00547) and FDC was funded by the RETICS Program (RIER, ISCIII, RD12/0009/0013).

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
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PLoS ONE
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE, Vol 11, Iss 8, p e0161305 (2016)
PLoS One
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

مصطلحات موضوعية: alelos, modelos logísticos, Genes clase I del complejo de histocompatibilidad (MHC), España, frecuencia génica, sitios genéticos, lcsh:Science, Diseases::Stomatognathic Diseases::Mouth Diseases::Behcet Syndrome [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Histocompatibility Antigens Class I::HLA-B Antigens [Medical Subject Headings], Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings], Immunoassay, education.field_of_study, Behcet Syndrome, Genomics, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Logistic Models [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings], Mhc class-i, Genotyping, estudios de casos y controles, Locus (genetics), Human leukocyte antigen, subunidad p35 de la interleucina-12, 03 medical and health sciences, Contactins, Rheumatoid-arthritis, Genetics, Genome-Wide Association Studies, Genetic predisposition, Humans, Molecular Biology Techniques, education, Molecular Biology, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids [Medical Subject Headings], síndrome de Behçet, Alleles, Molecular Biology Assays and Analysis Techniques, Sclerosis, lcsh:R, Biology and Life Sciences, Computational Biology, Receptors, Interleukin, 030104 developmental biology, Logistic Models, Genetic Loci, HLA-B Antigens, Case-Control Studies, lcsh:Q, Síndrome de Behçet, Genotipo, Models, Molecular, 0301 basic medicine, humanos, lcsh:Medicine, HLA-A3 Antigen, Genetic analysis, Geographical Locations, Gene Frequency, antígeno HLA-A3, Il23r-il12rb2, Aminoácidos, Multidisciplinary, antígeno HLA-B51, Genome-wide association, Antígenos HLA-B, antígenos HLA-B, Modelos logísticos, Europe, Peptide, Amino Acid Analysis, HLA-B51 Antigen, Alelos, Research Article, Risk, Population, Biology, Research and Analysis Methods, Genetic Predisposition, inmunoanálisis, Interleukin-12 Subunit p35, Genetic Predisposition to Disease, Allele, Allele frequency, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Imputation, contactinas, Human Genetics, predisposición genética a la enfermedad, Binding, Genome Analysis, Microarray Analysis, Spain, Genetics of Disease, People and Places, análisis por micromatrices, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Major Histocompatibility Complex::Genes, MHC Class I [Medical Subject Headings]

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc18beb47f051b877f81a476ce0e1e2
https://hdl.handle.net/10668/19157

المؤلفون: Jennifer N. Todd, Andrew W. Taylor, Geoffrey A. Walford, Maegan Harden, Deborah J. Wexler, Jaclyn Davis, Melissa K. Thomas, Janet Lo, Varinderpal Kaur, Jose C. Florez, Ling Chen, Katherine R. Littleton, Rachel J. Ackerman, Rebecca R. Fanelli, Bindu Chamarthi, Paul L. Huang, Corinne Barbato, Liana K. Billings, Allison B. Goldfine, A. Sofia Warner, Elliot S. Stolerman, Alisa K. Manning, Allan F. Moore, Sabina Q. Khan, Richard W. Grant, Rita M. McCarthy, Margo S. Hudson, Chunmei Huang, Marlene Fernandez, Alicia M. Hernandez, Rosa Bui, Laurel Garber, Amelia Lanier, Natalia Colomo

المساهمون: [Walford,GA, Colomo,N, Todd,JN, Billings,LK, Fernandez,M, Warner,AS, Davis,J, Littleton,KR, Hernandez,AM, Fanelli,RR, Lanier,A, Ackerman,RJ, Khan,SQ, Stolerman,ES, Moore,AF, Kaur,V, Taylor,A, Chen,L, Manning,AK, Florez,JC] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America. [Walford,GA, Wexler,D, Thomas,MK, Florez,JC] Diabetes Research Center, Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America. [Walford,GA, Huang,C, Huang,P, Lo,J, Goldfine,A, Florez,JC] Harvard Medical School, Boston, Massachusetts, United States of America. [Colomo,N] Department of Endocrinology and Nutrition. Hospital Universitario Regional de Málaga. Instituto de Investigación Biomédica de Málaga (IBIMA). Málaga, Spain. [Todd,JN] Boston Children’s Hospital, Boston, Massachusetts, United States of America. [Billings,LK, ] Division of Endocrinology and Metabolism, NorthShore University Health System, Evanston, Illinois, United States of America. [Chamarthi,B] Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America. [Chamarthi,B, McCarthy,RM, Hudson,MS] Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America. [Barbato,C, Bui,R, Garber,L, Goldine,A] Joslin Diabetes Center, Boston, Massachusetts, United States of America. [Harden,M] Genomics Platform, Broad Institute, Cambridge, Massachusetts, United States of America. [Grant,RW] Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America., This work was conducted with support from National Institutes of Health/NIDDK awards R01 DK088214, R03 DK077675, and P30 DK036836, from the Joslin Clinical Research Center from its philanthropic donors, and the Harvard Catalyst: The Harvard Clinical and translational Science Center (National Center for Research Resources and the National Center for Advancing Translational Sciences, NIH Awards M01-RR-01066, 1 UL1 RR025758-04 and 8UL1TR000170-05 and financial contributions from Harvard University and its affiliated academic health care centers).

المصدر: PLoS ONE, Vol 10, Iss 3, p e0121553 (2015)
PLoS ONE

مصطلحات موضوعية: Blood Glucose, Male, Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings], medicine.medical_treatment, lcsh:Medicine, Type 2 diabetes, Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Hipoglicemiantes, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Insulina, Insulin, lcsh:Science, Genetics, Glucose tolerance test, Prueba de tolerancia a la glucosa, Multidisciplinary, medicine.diagnostic_test, Predisposición genética a la enfermedad, Middle Aged, Polimorfismo de nucleótido único, Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease [Medical Subject Headings], Metformin, 3. Good health, Phenotype, Treatment Outcome, Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Metformin [Medical Subject Headings], Female, Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Pharmacogenetics [Medical Subject Headings], Alelos, Fenotipo, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Clinical Chemistry Tests::Blood Chemical Analysis::Glucose Tolerance Test [Medical Subject Headings], Transcription Factor 7-Like 2 Protein, medicine.drug, Research Article, Adult, Blood sugar, Check Tags::Male [Medical Subject Headings], Hypoglycemia, Polymorphism, Single Nucleotide, Diabetes mellitus, medicine, Chemicals and Drugs::Biological Factors::Biological Markers [Medical Subject Headings], Named Groups::Persons::Age Groups::Adult [Medical Subject Headings], Proteína 2 similar al factor de transcripción 7, Humans, Hypoglycemic Agents, Genetic Predisposition to Disease, Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Alleles, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome [Medical Subject Headings], Aged, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide [Medical Subject Headings], business.industry, lcsh:R, Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], glipicida, Glucose Tolerance Test, medicine.disease, Biomarcadores, Check Tags::Female [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::TCF Transcription Factors::Transcription Factor 7-Like 2 Protein [Medical Subject Headings], Diabetes Mellitus, Type 2, Pharmacogenetics, Diabetes Mellitus, Tipo II, Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Sulfones::Sulfonylurea Compounds::Glipizide [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents [Medical Subject Headings], lcsh:Q, Resultado del tratamiento, business, Biomarkers, Glipizide, Glucosa sanguínea, Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose [Medical Subject Headings]

وصف الملف: application/pdf; image/tiff; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1fd33ae64402208a3389526cb0a931
http://europepmc.org/articles/PMC4374872?pdf=render

المؤلفون: Xavier Montalban, Elvira Munteis, David Ordóñez, Concepción Núñez, Jose E Martínez-Rodríguez, Elena Urcelay, José C. Álvarez-Cermeño, Rafael Arroyo, Miguel A. Ortiz, Antonio Alcina, Guillermo Izquierdo, Sunny Malhotra, Antonio García-Merino, Antonio Sánchez, Manuel Comabella, Luisa M. Villar, Fuencisla Matesanz

المساهمون: Instituto de Salud Carlos III, European Commission, Junta de Andalucía, [Ortiz,MA, Núñez,C, Urcelay,E] Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos(IdISSC), Madrid, Spain. [Ordóñez,D] Immunogenetics & Histocompatibility, Instituto de Investigación Sanitaria Puertade Hierro, Majadahonda, Madrid, Spain. [Alvarez-Cermeño,JC, Villar,LM] Departments of Immunology and Neurology, Multiple Sclerosis Unit, Hospital Ramon y Cajal, (IRYCIS), Madrid, Spain. [Martínez-Rodriguez,JE, Munteis,E] Neurology, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain. [Sánchez,AJ, Garcia Merino,A] Neuroimmunology, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain. [Arroyo,R] Multiple Sclerosis Unit, Neurology Department. Hospital Clínico S. Carlos, Instituto de Investigación Sanitaria S.Carlos (IdISSC), Madrid, Spain. [Izquierdo,G] Multiple Sclerosis Unit, Hospital Virgen Macarena, Sevilla, Spain. [Malhotra,S, Montalban,X, Comabella,M] Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain. [Alcina,A, Matesanz,F] Department of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina 'López Neyra', Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134414 (2015)

مصطلحات موضوعية: Multiple Sclerosis, European Continental Ancestry Group, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Major Histocompatibility Complex [Medical Subject Headings], lcsh:Medicine, Predisposición Genética a la Enfermedad, Genome-wide association study, Esclerosi múltiple, Disease, Biology, Major histocompatibility complex, Bioinformatics, Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis [Medical Subject Headings], White People, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Histocompatibility Antigens Class II::HLA-D Antigens::HLA-DR Antigens::HLA-DR beta-Chains::HLA-DRB1 Chains [Medical Subject Headings], Reacción en cadena de la polimerasa, medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, Receptors, Immunologic, lcsh:Science, Genetic Association Studies, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Genetic association, Genetics, Multidisciplinary, Malalties autoimmunitàries, Cadenas HLA-DRB1, Multiple sclerosis, lcsh:R, Complejo principal de histocompatibilidad, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction [Medical Subject Headings], Epistasis, Genetic, medicine.disease, Genetic architecture, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Molecular Epidemiology::Genome-Wide Association Study [Medical Subject Headings], Esclerosis múltiple, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Globulins::Serum Globulins::Immunoglobulins [Medical Subject Headings], biology.protein, lcsh:Q, Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings], Alelos, LILRA3, Gene Deletion, Research Article, HLA-DRB1 Chains, Estudio de asociación genómica completa Asociación del Genoma Completo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d6a2ebbd321bd2171cc5554961ab20
http://hdl.handle.net/10261/126466

المؤلفون: Marta E. Alarcón-Riquelme, Jesus Benitez, Sonia Cabrera, Andrés Soto-Varela, Juan Manuel Espinosa-Sanchez, Eduardo Martin-Sanz, Nicolas Perez, Gabriel Trinidad, Jose A. Lopez-Escamez, Jesus Fraile, Sofía Santos-Pérez, Manuel Martínez-Bueno, Paz Pérez, Teresa Requena, Elena Sánchez, Angel Batuecas, Ismael Aran

المساهمون: [Cabrera,S, Requena,T, Espinosa-Sanchez,JM, Lopez-Escamez,JA] Otology and Neurotology Group, Department of Genomic Medicine-Centro de Genómica e Investigación Oncológica-Pfizar/Universidad de Granada/Junta de Andalucía (Genyo). [Sanchez,E] Department of Neurology, Icahn School of Medicine at Mount Sinai. [Martinez-Bueno,M, Alarcon-Riquelme,ME] Group of Genetics of Complex Diseases, Department of Genomic Medicine-Centro de Genómica e Investigación Oncológica-Pfizer/Universidad de Granada/Junta de Andalucía (GENYO). [Benitez,J] Department of Otolaryngology, Hospital Universitario de Gran Canaria Dr. Negrin. [Perez,N] Department of Otolaryngology, Clínica Universidad de Navarra. [Trinidad,G] Division of Otoneurology, Department of Otorhinolaryngology, Complejo Hospitalario de Badajoz. [Soto-Varela,A, Santos-Perez,S] Division of Otoneurology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario, Santiago de Compostela. [Martin-Sanz,E] Department of Otolaryngology, Hospital Universitario de Getafe. [Fraile,J] Department of Otolaryngology, Hospital Miguel Servet. [Perez,P] Department of Otorhinolaryngology, Hospital Cabueñes. [Batuecas,A] Department of Otolaryngology, Hospital Universitario Salamanca. [Espinosa-Sanchez,JM] Department of Otorhinolaryngology, Hospital San Agustin. [Aran,I] Department of Otolaryngology, Complexo Hospital de Pontevedra. [Lopez-Escamez,JA] Department of Otoloaryngology, Hospital de Poniente., Research Grants PI09/00920 and PI13/1242 from Instituto de Salud Carlos III by FEDER Funds from the EU. The authors also acknowledge the COST Action BM1306 TINNET which supports part of their networking activities (http://tinnet.tinnitusresearch.net/).

المصدر: PLoS ONE, Vol 9, Iss 11, p e112171 (2014)
PLoS ONE
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Zaguán. Repositorio Digital de la Universidad de Zaragoza

مصطلحات موضوعية: Male, Linkage disequilibrium, Pathology, Desequilibrio de Ligamiento, Progresión de la Enfermedad, lcsh:Medicine, Otology, NFKB1 gene, Kaplan-Meier Estimate, Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Linkage Disequilibrium, Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Tinnitus, Mediana Edad, Hearing, Estimación de Kaplan-Meier, Medicine and Health Sciences, lcsh:Science, Masculino, Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Labyrinth Diseases::Endolymphatic Hydrops::Meniere Disease [Medical Subject Headings], Multidisciplinary, Femenino, Middle Aged, Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Hearing Disorders::Hearing Loss::Hearing Loss, Sensorineural [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Linkage::Linkage Disequilibrium [Medical Subject Headings], 3. Good health, Humanos, Sensorineural hearing loss, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::NF-kappa B::NF-kappa B p50 Subunit [Medical Subject Headings], Rheumatoid arthritis, Meniere's disease, Disease Progression, Female, Haplotipos, medicine.symptom, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::DNA, Intergenic::Introns [Medical Subject Headings], Alelos, Research Article, medicine.medical_specialty, Hearing loss, Hearing Loss, Sensorineural, Immunology, Predisposición Genética a la Enfermedad, Check Tags::Male [Medical Subject Headings], Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Autoimmune Diseases, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease [Medical Subject Headings], Genetics, medicine, otorhinolaryngologic diseases, Humans, Intrones, Genetic Predisposition to Disease, Alleles, Meniere Disease, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Ankylosing spondylitis, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide [Medical Subject Headings], Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis::Kaplan-Meier Estimate [Medical Subject Headings], business.industry, Enfermedad de Meniere, lcsh:R, NF-kappa B p50 Subunit, Biology and Life Sciences, Pérdida Auditiva, medicine.disease, Introns, FN-kappa B, Haplotypes, Otorhinolaryngology, Check Tags::Female [Medical Subject Headings], Genetics of Disease, Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Neurologic Manifestations::Sensation Disorders::Hearing Disorders::Hearing Loss [Medical Subject Headings], Clinical Immunology, lcsh:Q, Polimorfismo de Nucleótido Simple, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67d4446cb022a5f50e5eb5b88219357
https://hdl.handle.net/10668/2060

المؤلفون: Miguel A. González-Gay, María Carmen Cenit, Mario Martínez-Florensa, Carles Tolosa, Noelia Armiger, Ana Suárez, Francisco Hernandez, Elena Carnero-Montoro, Javier Martín, Francisco Lozano, Norberto Ortego-Centeno, Enrique de Ramón, Elena Bosch, Miguel Caballero-Baños, M.T. Arias, José Mario Sabio, Daniel Benitez, Marta Consuegra, Lizette Bonet

المساهمون: Universidad de Cantabria, Universitat de Barcelona, Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Junta de Andalucía, European Commission, Instituto de Salud Carlos III, [Cenit,MC, Martín,J] Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain. [Martínez-Florensa,M] ImmunNovative Developments, Barcelona, Spain. [Martínez-Florensa,M, Consuegra,M, Bonet,L, Armiger,N, Benitez,D, Lozano,F] Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. [Carnero-Montoro,E, Bosch,L] Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Departament de Ciències Experimentals i de la Salut, Parc de Recerca Biomèdica de Barcelona, Barcelona, Spain. [Caballero-Baños,M, Arias,MT, Lozano,F] Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain. [Ortego-Centeno,N] Department of Internal Medicine, Hospital Clínico San Cecilio, Granada, Spain. [de Ramón,E] Department of Internal Medicine, Hospital Carlos Haya, Málaga, Spain. [Sabio,JM] Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Spain. [García–Hernández,FJ] Department of Internal Medicine, Hospital Virgen del Rocío, Seville, Spain. [Tolosa,C] Department of Internal Medicine, Hospital Parc Taulí, Sabadell, Spain. [Suárez,A] Department of Functional Biology, Immunology Area, Faculty of Medicine, University of Oviedo, Oviedo, Spain. [González-Gay,MA] Department of Rheumatology, Hospital Marques de Valdecilla, IFIMAV, Santander, Spain. [Lozano,F] Departament de Biologia Cel•lular, Immunologia i Neurociencies, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain., This work was supported by grants from the Spanish Ministerio de Economía y Competitividad [SAF2010-19717 to FL, SAF2009-11110 to JM, SAF2011-29239, and BFU2008-01046 to EB], Generalitat de Catalunya [2009SGR00252 to FL, and 2009SGR1101 to EB], Junta de Andalucı´a [CTS-4977], and Instituto de Salud Carlos III and Fondo Europeo de Desarrollo Regional/FEDER [RD12/0009/0004 to JM]

المصدر: PLoS ONE, Vol 9, Iss 11, p e113090 (2014)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
PLoS One. 2014 Nov 17;9(11):e113090
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Recercat. Dipósit de la Recerca de Catalunya
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona

مصطلحات موضوعية: Phenomena and Processes::Immune System Phenomena::Immunity::Autoimmunity [Medical Subject Headings], Diseases::Immune System Diseases::Autoimmune Diseases::Lupus Erythematosus, Systemic::Lupus Nephritis [Medical Subject Headings], T-Lymphocytes, Lymphocyte, Lupus nephritis, Polimorfismo genético, Autoimmunity, Lymphocyte Activation, medicine.disease_cause, Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], immune system diseases, Nefritis lúpica, Medicine and Health Sciences, Lupus Erythematosus, Systemic, Immunologia, Lymphocytes, Genetics, Multidisciplinary, Estudios de casos y controles, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies [Medical Subject Headings], Diseases::Immune System Diseases::Autoimmune Diseases::Lupus Erythematosus, Systemic [Medical Subject Headings], Predisposición genética a la enfermedad, Lupus Nephritis, Humanos, medicine.anatomical_structure, Medicine, Haplotipos, Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings], Alelos, Nephritis, Research Article, Genotype, Inflammatory Diseases, T cell, Science, Immunology, Antígenos CD5, Single-nucleotide polymorphism, Autoinmunidad, CD5 Antigens, Limfòcits, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease [Medical Subject Headings], Rheumatology, Lupus eritematós sistèmic, Lupus eritematoso sistémico, medicine, Humans, Genetic Predisposition to Disease, Allele, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Alleles, Polymorphism, Genetic, Lupus erythematosus, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Antigens, CD58 [Medical Subject Headings], business.industry, Haplotype, Biology and Life Sciences, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic [Medical Subject Headings], medicine.disease, Haplotypes, Case-Control Studies, Lupus eritematós, business, Genotipo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6076471a05f5f12adaed5284e95dee99
https://doaj.org/article/4537e8dc69274d5884daf56bc991fcbd

المؤلفون: Miguel Ferrer, Eduardo Collantes, Teresa Vallejo, Alejandro Escudero, Rafael Cáliz, Helena Canhão, Manuela Expósito-Ruiz, Lurdes Romani, Asta Försti, Kari Hemminki, João Eurico Fonseca, Alfonso González-Utrilla, Antonio García, Eva Perez-Pampin, Carmen Belén Lupiañez, María José Soto-Pino, I. Filipescu, Juan Sainz, L. M. Canet, Juana Segura-Catena

المساهمون: [Cáliz,R, Soto-Pino,MJ, Ferrer,MA, García,A, Romani,L, González-Utrilla,A, Vallejo,T] Rheumatology Department, Virgen de las Nieves University Hospital, Granada, Spain. [Canet,LM, Lupiañez,CB, Segura-Catena,J, Sainz,J] Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain. [Canhão,H, Fonseca,JE] Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. Rheumatology Department, Santa Maria Hospital–CHLN, Lisbon, Portugal. [Escudero,A, Filipescu,I, Collantes,E] Rheumatology Department, Reina Sofía Hospital, Córdoba, Spain. [Expósito-Ruiz,M] FIBAO Fundation, Virgen de las Nieves University Hospital, Granada, Spain. [Pérez-Pampin,E] Rheumtology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain. [Hemminki,K, Försti,A, Sainz,J] Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany. [Hemminki,K, Försti,A] Center for Primary Health Care Research, Clinical Research Center, Malmö, Sweden., This study was partially supported by grants P08-CVI-4116 from Consejerı´a de Salud de la Junta de Andalucia (Sevilla, Spain) and PI08/1051 and PI12/02688 from Fondo de Investigaciones Sanitarias (Madrid, Spain).

المصدر: PLoS ONE
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
PLoS ONE; 8(8), no e72732 (2013)
PLoS ONE, Vol 8, Iss 8, p e72732 (2013)

مصطلحات موضوعية: Male, CCR2, Multifactor Dimensionality Reduction, lcsh:Medicine, Disease, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lectins [Medical Subject Headings], Gastroenterology, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Arthritis, Rheumatoid, Risk Factors, lcsh:Science, Masculino, Chemokine CCL2, Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets::T-Lymphocytes, Helper-Inducer::Th1 Cells [Medical Subject Headings], Células TH1, Immunity, Cellular, Sex Characteristics, Multidisciplinary, Femenino, Public Health, Global Health, Social Medicine and Epidemiology, Middle Aged, Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease [Medical Subject Headings], Humanos, Rheumatoid arthritis, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk [Medical Subject Headings], Artritis Reumatoide, Female, Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings], Sex characteristics, Research Article, medicine.medical_specialty, Receptors, CCR2, Inmunidad Celular, Check Tags::Male [Medical Subject Headings], Predisposición Genética a la Enfermedad, Single-nucleotide polymorphism, Células Th17, Lectinas, Receptors, Cell Surface, Biology, Riesgo, Polymorphism, Single Nucleotide, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Lectins, C-Type, Allele, Gene, Demography, Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets::T-Lymphocytes, Helper-Inducer::Th17 Cells [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide [Medical Subject Headings], Multifactor dimensionality reduction, lcsh:R, Th1 Cells, medicine.disease, Check Tags::Female [Medical Subject Headings], Diseases::Immune System Diseases::Autoimmune Diseases::Arthritis, Rheumatoid [Medical Subject Headings], Immunology, Th17 Cells, lcsh:Q, Polimorfismo de Nucleótido Simple, Genotipo, Cell Adhesion Molecules

وصف الملف: application/pdf; application/vnd.oasis.opendocument.text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e323f183397652d137bca1f1f6c9b88d
http://europepmc.org/articles/PMC3758336

المؤلفون: María Francisca González-Escribano, Lina-Marcela Diaz-Gallo, Norberto Ortego-Centeno, Torsten Witte, Enrique de Ramón, Francisco J. García-Hernández, Hans-Joachim Anders, José Mario Sabio, Elena Sánchez, Miguel A. González-Gay, Javier Martín

المساهمون: [Diaz-Gallo,LM, Sánchez,E, Martin,J] Cellular Biology and Immunology Department, Instituto de Parasitología y Biomedicina ‘‘López-Neyra’’, Consejo Superior de Investigaciones Científicas (IPBLN- Consejo Superior de Investigaciones Científicas), Granada, Spain. [Ortego-Centeno,N] Department of Internal Medicine, Hospital Clínico San Cecilio, Granada, Spain. [Sabio,JM] Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Spain. [García-Hernández,FJ] Department of Internal Medicine, Hospital Virgen del Rocío, Sevilla, Spain. [Ramón,E de] Department of Internal Medicine, Hospital Carlos Haya, Málaga, Spain. [González-Gay,MA] Department of Rheumatology, Instituto de Formación e Investigación Marqués de Valdecilla, Hospital Universitario Marqués de Valdecilla, Santander, Spain. [Witte,T] Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany. [Anders,HJ] Medical department and policlinic IV, Klinikum der Universitat, München, Munich, Germany. [González-Escribano,MF] Department of Immunology, Hospital Virgen del Rocío, Sevilla, Spain., This work was partially supported by RETICS Program, RD08/0075 (RIER) from Instituto de Salud Carlos III, within the VI PN de I+D+i 2008-2011 (FEDER) and grant KFO 250, TP 03, WI 1031/6-1 LMDG was supported by the 'Ayudas Predoctorales de Formación en Investigación en Salud (PFIS - FI09/00544)' from the 'Instituto de Salud Carlos III'.

المصدر: PLoS ONE, Vol 8, Iss 4, p e60646 (2013)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE

مصطلحات موضوعية: Genetic Screens, Linkage disequilibrium, Desequilibrio de Ligamiento, Epidemiology, LOCI, lcsh:Medicine, Genome-wide association study, ComputingMilieux_LEGALASPECTSOFCOMPUTING, Autoimmunity, Pathogenesis, VARIANTS, medicine.disease_cause, Biochemistry, Linkage Disequilibrium, DISEASE, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Risk Factors, Genotype, Genetics of the Immune System, Lupus Erythematosus, Systemic, lcsh:Science, ComputingMilieux_MISCELLANEOUS, Multidisciplinary, Genomics, Humanos, Genetic Epidemiology, Cohort, Medicine, Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings], Alelos, Research Article, EXPRESSION, UBASH3A protein, human, Quantitative Trait Loci, Immunology, Predisposición Genética a la Enfermedad, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Microbiology, Systemic Lupus Erythematosus, Autoimmune Diseases, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease [Medical Subject Headings], Genomic Medicine, Rheumatology, Genome Analysis Tools, Phenomena and Processes::Genetic Phenomena::Genetic Linkage [Medical Subject Headings], Genetic variation, Genetics, medicine, Humans, Genetic Predisposition to Disease, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Adaptor Proteins, Signal Transducing [Medical Subject Headings], Genetic Testing, Allele, GENOME-WIDE ASSOCIATION, Alleles, Genetic Association Studies, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings], Adaptor Proteins, Signal Transducing, Proteínas Adaptadoras Transductoras de Señales, Clinical Genetics, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide [Medical Subject Headings], Population Biology, Lupus Eritematoso Sistémico, lcsh:R, Proteins, Computational Biology, Human Genetics, Sitios de Carácter Cuantitativo, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genetic Loci::Quantitative Trait Loci [Medical Subject Headings], Diseases::Skin and Connective Tissue Diseases::Connective Tissue Diseases::Lupus Erythematosus, Systemic [Medical Subject Headings], Data_GENERAL, Genetics of Disease, Genetic Polymorphism, T-Cell Receptors, Clinical Immunology, lcsh:Q, Polimorfismo de Nucleótido Simple, Population Genetics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23be62fd97726db6a461cefe33b2dcb9
https://hdl.handle.net/10668/1421