المؤلفون: Schneider H; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Schubert KM; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Blodow S; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Kreutz CP; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Erdogmus S; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Wiedenmann M; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Qiu J; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Fey T; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Ruth P; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Lubomirov LT; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Pfitzer G; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Mederos Y Schnitzler M; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Hardie DG; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Gudermann T; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.)., Pohl U; From the Walter-Brendel Centre of Experimental Medicine and Biomedical Center (H.S., K.M.S., S.B., C.-P.K., M.W., J.Q., T.F., U.P.) and Walther Straub Institute, Pharmacology (S.E., M.M.y.S., T.G.), Ludwig-Maximilians Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (H.S., K.M.S., S.B., U.P.); DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (H.S., K.M.S., S.B., T.F., M.M.y.S., T.G., U.P.); Division of Cell Signalling and Immunology, University of Dundee, Scotland, United Kingdom (D.G.H.); Institute of Vegetative Physiology, University of Cologne, Köln, Germany (L.T.L., G.P.); and Pharmacology, Toxicology and Clinical Pharmacy, Department of Pharmacy, Universität Tübingen, Tübingen, Germany (P.R.). upohl@lmu.de.

المصدر: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2015 Jul; Vol. 66 (1), pp. 108-16. Date of Electronic Publication: 2015 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases/*physiology , Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/*physiology , Muscle, Smooth, Vascular/*drug effects , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*physiology , Vascular Resistance/*drug effects , Vasodilation/*drug effects , Vasomotor System/*drug effects, Animals ; Calcium Signaling/drug effects ; Calcium Signaling/physiology ; Calcium-Binding Proteins/metabolism ; Cells, Cultured ; Cricetinae ; Enzyme Activation/drug effects ; Indoles/pharmacology ; Membrane Potentials/drug effects ; Mesocricetus ; Mice ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/physiology ; Peptides/pharmacology ; RNA, Messenger/biosynthesis ; Thapsigargin/pharmacology ; Vascular Resistance/physiology ; Vasodilation/physiology ; Vasomotor System/physiology

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