المؤلفون: Halievski K; Neuroscience Program, 108 Giltner Hall, Michigan State University, East Lansing, MI 48824-1115, USA. k.halievski@gmail.com., Nath SR; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. nathsr@med.umich.edu., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. ka2no@med.nagoya-u.ac.jp., Adachi H; Department of Neurology, University of Occupational and Environment Health School of Medicine, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu Fukuoka 807-8555, Japan. hiadachi@med.uoeh-u.ac.jp., Sobue G; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. sobueg@med.nagoya-u.ac.jp., Breedlove SM; Neuroscience Program, 108 Giltner Hall, Michigan State University, East Lansing, MI 48824-1115, USA. breedsm@msu.edu., Lieberman AP; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. liebermn@med.umich.edu., Jordan CL; Neuroscience Program, 108 Giltner Hall, Michigan State University, East Lansing, MI 48824-1115, USA. jordancy@msu.edu.; Physiology Department, 108 Giltner Hall, Michigan State University, East Lansing, MI 48824-1115, USA. jordancy@msu.edu.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2019 Mar 15; Vol. 20 (6). Date of Electronic Publication: 2019 Mar 15.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Brain-Derived Neurotrophic Factor/*genetics , Brain-Derived Neurotrophic Factor/*metabolism , Muscle, Skeletal/*metabolism , Muscular Atrophy, Spinal/*genetics , Receptors, Androgen/*genetics, Animals ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Knock-In Techniques ; Humans ; Male ; Mice ; Mice, Transgenic ; Muscular Atrophy, Spinal/metabolism ; Rats ; Receptors, Androgen/metabolism

المؤلفون: Sahashi K; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan, ka2no@med.nagoya-u.ac.jp sobueg@med.nagoya-u.ac.jp., Hung G; Isis Pharmaceuticals, Carlsbad, CA 92008, USA and., Adachi H; Department of Neurology, University of Occupational and Environmental Health School of Medicine, Kitakyushu 807-8555, Japan., Kondo N; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Nakatsuji H; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Tohnai G; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Iida M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Bennett CF; Isis Pharmaceuticals, Carlsbad, CA 92008, USA and., Sobue G; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan, ka2no@med.nagoya-u.ac.jp sobueg@med.nagoya-u.ac.jp.

المصدر: Human molecular genetics [Hum Mol Genet] 2015 Nov 01; Vol. 24 (21), pp. 5985-94. Date of Electronic Publication: 2015 Jul 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Muscular Atrophy, Spinal/*genetics , Receptors, Androgen/*genetics, Animals ; Disease Progression ; Gene Expression/drug effects ; Gene Silencing ; Mice ; Mice, Transgenic ; Motor Neurons ; Muscle, Skeletal/pathology ; Muscular Atrophy, Spinal/pathology ; Muscular Atrophy, Spinal/therapy ; Mutation ; Neuromuscular Junction/pathology ; Oligonucleotides, Antisense/administration & dosage

المؤلفون: Tanaka S; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan; Department of Speech Pathology and Audiology, Aichi-Gakuin University School of Health Science, 12 Araike, Iwasaki-cho, Nisshin 470-0195, Japan., Banno H; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Suzuki K; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Suga N; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Hashizume A; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Mano T; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Araki A; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Watanabe H; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Adachi H; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Tatsumi H; Department of Speech Pathology and Audiology, Aichi-Gakuin University School of Health Science, 12 Araike, Iwasaki-cho, Nisshin 470-0195, Japan., Yamamoto M; Department of Speech Pathology and Audiology, Aichi-Gakuin University School of Health Science, 12 Araike, Iwasaki-cho, Nisshin 470-0195, Japan., Sobue G; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. Electronic address: sobueg@med.nagoya-u.ac.jp.

المصدر: Journal of the neurological sciences [J Neurol Sci] 2014 Feb 15; Vol. 337 (1-2), pp. 193-200. Date of Electronic Publication: 2013 Dec 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375403 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5883 (Electronic) Linking ISSN: 0022510X NLM ISO Abbreviation: J Neurol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Auditory Perceptual Disorders/*etiology , Laryngismus/*complications , Muscular Atrophy, Spinal/*complications , Vocal Cords/*physiopathology , Voice Quality/*physiology, Acoustic Stimulation ; Adult ; Aged ; Humans ; Laryngismus/genetics ; Male ; Middle Aged ; Muscular Atrophy, Spinal/genetics ; ROC Curve ; Receptors, Androgen/genetics ; Severity of Illness Index ; Statistics, Nonparametric ; Trinucleotide Repeat Expansion/genetics

المؤلفون: Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan. ka2no@med.nagoya-u.ac.jp, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G

المصدر: Progress in neurobiology [Prog Neurobiol] 2012 Dec; Vol. 99 (3), pp. 246-56. Date of Electronic Publication: 2012 May 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0370121 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5118 (Electronic) Linking ISSN: 03010082 NLM ISO Abbreviation: Prog Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: Muscular Atrophy, Spinal/*therapy, Animals ; Humans ; Muscular Atrophy, Spinal/diagnosis ; Muscular Atrophy, Spinal/etiology ; Muscular Atrophy, Spinal/genetics ; Muscular Disorders, Atrophic/genetics ; Muscular Disorders, Atrophic/metabolism ; Muscular Disorders, Atrophic/pathology ; Peptides/metabolism ; Protein Processing, Post-Translational ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Trinucleotide Repeats/genetics

المؤلفون: Miyazaki Y; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G

المصدر: Nature medicine [Nat Med] 2012 Jul; Vol. 18 (7), pp. 1136-41.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Gene Silencing* , Genetic Therapy*, Dependovirus/*genetics , MicroRNAs/*genetics , Muscular Atrophy, Spinal/*genetics , Muscular Atrophy, Spinal/*prevention & control , Nerve Tissue Proteins/*genetics , RNA-Binding Proteins/*genetics, Aged ; Animals ; Base Sequence ; CELF Proteins ; Exons/genetics ; Gene Expression Regulation ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Male ; Mice ; MicroRNAs/chemistry ; MicroRNAs/metabolism ; MicroRNAs/therapeutic use ; Middle Aged ; Molecular Sequence Data ; Muscular Atrophy, Spinal/pathology ; Mutant Proteins/metabolism ; Nerve Tissue Proteins/metabolism ; Nucleic Acid Conformation ; Phenotype ; RNA Stability/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Rotarod Performance Test

المؤلفون: Mo K; Department of Psychology, University of Toronto at Mississauga, Mississauga, Ontario, Canada., Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA

المصدر: PloS one [PLoS One] 2010 Sep 23; Vol. 5 (9), pp. e12922. Date of Electronic Publication: 2010 Sep 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Mice*, Bulbo-Spinal Atrophy, X-Linked/*genetics , Muscle, Skeletal/*metabolism , Muscular Atrophy, Spinal/*genetics, Animals ; Bulbo-Spinal Atrophy, X-Linked/metabolism ; Female ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Muscular Atrophy, Spinal/metabolism ; Oligonucleotide Array Sequence Analysis

المؤلفون: Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan. ka2no@med.nagoya-u.ac.jp, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2010 Apr 21; Vol. 30 (16), pp. 5702-12.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Muscular Atrophy, Spinal/*genetics , Muscular Atrophy, Spinal/*metabolism , Muscular Disorders, Atrophic/*genetics , Muscular Disorders, Atrophic/*metabolism , Transforming Growth Factor beta/*genetics, Aged ; Animals ; Humans ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Motor Neurons/metabolism ; Motor Neurons/pathology ; Muscular Atrophy, Spinal/pathology ; Muscular Disorders, Atrophic/pathology ; Nerve Degeneration/genetics ; Nerve Degeneration/metabolism ; Nerve Degeneration/pathology ; Signal Transduction/physiology ; Transforming Growth Factor beta/antagonists & inhibitors ; Transforming Growth Factor beta/physiology

المؤلفون: Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. ka2no@med.nagoya-u.ac.jp, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G

المصدر: Advances in experimental medicine and biology [Adv Exp Med Biol] 2010; Vol. 685, pp. 64-74.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

مواضيع طبية MeSH: Muscular Atrophy, Spinal*/genetics , Muscular Atrophy, Spinal*/metabolism , Muscular Atrophy, Spinal*/pathology , Muscular Atrophy, Spinal*/physiopathology , Receptors, Androgen*/genetics , Receptors, Androgen*/metabolism , Trinucleotide Repeat Expansion*, Animals ; Anterior Horn Cells/metabolism ; Anterior Horn Cells/pathology ; Anterior Horn Cells/physiopathology ; Brain Stem/metabolism ; Brain Stem/pathology ; Brain Stem/physiopathology ; Female ; Heterozygote ; Homozygote ; Humans ; Male ; Motor Neurons/metabolism ; Motor Neurons/pathology ; Sex Characteristics

المؤلفون: Palazzolo I; Neurogenetics Branch, NINDS, NIH, Bethesda, MD 20892, USA., Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M

المصدر: Neuron [Neuron] 2009 Aug 13; Vol. 63 (3), pp. 316-28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation/*genetics , Insulin-Like Growth Factor I/*genetics , Insulin-Like Growth Factor I/*metabolism , Muscle, Skeletal/*metabolism , Muscular Atrophy/*physiopathology , Muscular Atrophy, Spinal/*genetics , Muscular Atrophy, Spinal/*pathology, Animals ; Behavior, Animal/drug effects ; Behavior, Animal/physiology ; Cell Line, Transformed ; Chlorocebus aethiops ; Class I Phosphatidylinositol 3-Kinases ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation/drug effects ; Humans ; Insulin-Like Growth Factor I/pharmacology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Muscle Proteins/genetics ; Muscle Proteins/metabolism ; Muscle, Skeletal/drug effects ; Muscular Atrophy, Spinal/mortality ; Muscular Atrophy, Spinal/therapy ; Mutation/genetics ; Oncogene Protein v-akt/metabolism ; Peptides/genetics ; Peptides/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation/drug effects ; Phosphorylation/genetics ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Serine/metabolism ; Time Factors ; Transfection/methods ; Trinucleotide Repeat Expansion/drug effects ; Trinucleotide Repeat Expansion/physiology ; Ubiquitin/metabolism

المؤلفون: Tokui K; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan., Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G

المصدر: Human molecular genetics [Hum Mol Genet] 2009 Mar 01; Vol. 18 (5), pp. 898-910. Date of Electronic Publication: 2008 Dec 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Benzoquinones/*administration & dosage , Lactams, Macrocyclic/*administration & dosage , Motor Neurons/*metabolism , Muscular Atrophy, Spinal/*drug therapy , Peptides/*metabolism , Proteasome Endopeptidase Complex/*metabolism , Receptors, Androgen/*metabolism, Animals ; Disease Models, Animal ; Mice ; Mice, Transgenic ; Motor Neurons/drug effects ; Muscular Atrophy, Spinal/genetics ; Muscular Atrophy, Spinal/metabolism ; Proteasome Endopeptidase Complex/genetics ; Receptors, Androgen/genetics ; Ubiquitin/genetics ; Ubiquitin/metabolism