المؤلفون: Eivind Hovig, Bernardo Bonanni, Monika Morak, Mark A. Jenkins, Patricia Esperon, Toni T. Seppälä, Lone Sunde, Pablo Kalfayan, Gabriel Capellá, Inge Bernstein, Matilde Navarro, Marc S. Greenblatt, John Burn, Zohreh Ketabi, Johanna Tecklenburg, Francisco Lopez-Koestner, Miriam Mints, Heike Görgens, Neil A J Ryan, Kate Green, Annika Auranen, Douglas Tjandra, Robert W. Haile, Marta Pineda, Tamara Alejandra Piñero, Stefan Aretz, Robert Hüneburg, Verena Steinke-Lange, Markus Loeffler, Christina Therkildsen, John L. Hopper, Deepak Vangala, Huw Thomas, Reinhard Büttner, James Hill, Einar Andreas Rødland, Revital Kariv, Maria Grazia Tibiletti, Sigve Nakken, Stefanie Holzapfel, D. Gareth Evans, Oliver G. Denton, Julian R. Sampson, Henrik Okkels, Joan Vidal, Loic Le Marchand, Hans Georg Strauß, Gabriela Möslein, Claudia Perne, Ingrid Winship, Nathan Gluck, Jane C. Figueiredo, Mev Dominguez-Valentin, Wolff Schmiegel, Karl Heinimann, Kirsi Pylvänäinen, Karin Alvarez, Maartje Nielsen, Wouter H. de Vos tot Nederveen Cappel, Fiona Lalloo, Aung Ko Win, Guy Rosner, Carlos A. Vaccaro, Polly A. Newcomb, Elke Holinski-Feder, John-Paul Plazzer, Lior H. Katz, Christoph Engel, Anna Lepistö, Jukka-Pekka Mecklin, Giulia Martina Cavestro, Adriana Della Valle, Finlay A. Macrae, Sanne W. ten Broeke, Florencia Neffa, Rolf H. Sijmons, María Laura Gonzalez, Nils Rahner, Jürgen Weitz, Hans F. A. Vasen, Stephen N. Thibodeau, Emma J Crosbie, Lucio Bertario, Steven Gallinger, Noralane M. Lindor, Pål Møller, Laura Renkonen-Sinisalo, Magnus von Knebel Doeberitz

المساهمون: Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Nakken, S., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C. A., Green, K., Lalloo, F., Hill, J., Schmiegel, W., Vangala, D., Perne, C., Strauss, H. -G., Tecklenburg, J., Holinski-Feder, E., Steinke-Lange, V., Mecklin, J. -P., Plazzer, J. -P., Pineda, M., Navarro, M., Vidal, J. B., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Ryan, N., ten Broeke, S. W., Jenkins, M. A., Sunde, L., Bernstein, I., Burn, J., Greenblatt, M., de Vos tot Nederveen Cappel, W. H., Della Valle, A., Lopez-Koestner, F., Alvarez, K., Buttner, R., Gorgens, H., Morak, M., Holzapfel, S., Huneburg, R., von Knebel Doeberitz, M., Loeffler, M., Rahner, N., Weitz, J., Pylvanainen, K., Renkonen-Sinisalo, L., Lepisto, A., Auranen, A., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Therkildsen, C., Okkels, H., Ketabi, Z., Denton, O. G., Rodland, E. A., Vasen, H., Neffa, F., Esperon, P., Tjandra, D., Moslein, G., Sampson, J. R., Evans, D. G., Seppala, T. T., Moller, P., ATG - Applied Tumor Genomics, HUS Abdominal Center, II kirurgian klinikka, Department of Surgery, Clinicum, Helsinki University Hospital Area, University of Helsinki

المصدر: Genetics in Medicine, 23(4), 705-712. Nature Publishing Group
Dominguez-Valentin, M, Crosbie, E J, Engel, C, Aretz, S, Macrae, F, Winship, I, Capella, G, Thomas, H, Nakken, S, Hovig, E, Nielsen, M, Sijmons, R H, Bertario, L, Bonanni, B, Tibiletti, M G, Cavestro, G M, Mints, M, Gluck, N, Katz, L, Heinimann, K, Vaccaro, C A, Green, K, Lalloo, F, Hill, J, Schmiegel, W, Vangala, D, Perne, C, Strauss, H-G, Tecklenburg, J, Holinski-Feder, E, Steinke-Lange, V, Mecklin, J-P, Plazzer, J-P, Pineda, M, Navarro, M, Brunet Vidal, J, Kariv, R, Rosner, G, Alejandra Pinero, T, Laura Gonzalez, M, Kalfayan, P, Ryan, N, Ten Broeke, S W, Jenkins, M A, Sunde, L, Bernstein, I, Burn, J, Greenblatt, M, Cappel, W H D V T N, Della Valle, A, Lopez-Koestner, F, Alvarez, K, Buettner, R, Goergens, H, Morak, M, Holzapfel, S, Hueneburg, R, Doeberitz, M V K, Loeffler, M, Rahner, N, Weitz, J, Pylvanainen, K, Renkonen-Sinisalo, L, Lepisto, A, Auranen, A, Hopper, J L, Win, A K, Haile, R W, Lindor, N M, Gallinger, S, Le Marchand, L, Newcomb, P A, Figueiredo, J C, Thibodeau, S N, Therkildsen, C, Okkels, H, Ketabi, Z, Denton, O G, Rodland, E A, Vasen, H, Neffa, F, Esperon, P, Tjandra, D, Moeslein, G, Sampson, J R, Evans, D G, Seppala, T T & Moller, P 2021, ' Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants : a Prospective Lynch Syndrome Database report ', Genetics in Medicine, vol. 23, no. 4, pp. 705-712 . https://doi.org/10.1038/s41436-020-01029-1
Dominguez-Valentin, M, Crosbie, E J, Engel, C, Aretz, S, Macrae, F, Winship, I, Capella, G, Thomas, H, Nakken, S, Hovig, E, Nielsen, M, Sijmons, R H, Bertario, L, Bonanni, B, Tibiletti, M G, Cavestro, G M, Mints, M, Gluck, N, Katz, L, Heinimann, K, Vaccaro, C A, Green, K, Lalloo, F, Hill, J, Schmiegel, W, Vangala, D, Perne, C, Strauß, H G, Tecklenburg, J, Holinski-Feder, E, Steinke-Lange, V, Mecklin, J P, Plazzer, J P, Pineda, M, Navarro, M, Vidal, J B, Kariv, R, Rosner, G, Piñero, T A, Gonzalez, M L, Kalfayan, P, Ryan, N, ten Broeke, S W, Jenkins, M A, Sunde, L, Bernstein, I, Burn, J, Greenblatt, M, de Vos tot Nederveen Cappel, W H, Della Valle, A, Lopez-Koestner, F, Alvarez, K, Büttner, R, Görgens, H, Morak, M, Holzapfel, S, Hüneburg, R, von Knebel Doeberitz, M, Loeffler, M, Rahner, N, Weitz, J, Pylvänäinen, K, Renkonen-Sinisalo, L, Lepistö, A, Auranen, A, Hopper, J L, Win, A K, Haile, R W, Lindor, N M, Gallinger, S, Le Marchand, L, Newcomb, P A, Figueiredo, J C, Thibodeau, S N, Therkildsen, C, Okkels, H, Ketabi, Z, Denton, O G, Rødland, E A, Vasen, H, Neffa, F, Esperon, P, Tjandra, D, Möslein, G, Sampson, J R, Evans, D G, Seppälä, T T & Møller, P 2021, ' Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants : a Prospective Lynch Syndrome Database report ', Genetics in Medicine, vol. 23, no. 4, pp. 705–712 . https://doi.org/10.1038/s41436-020-01029-1
Genetics in Medicine, 23(4), 705-712. SPRINGERNATURE
Dominguez-Valentin, M, Crosbie, E J, Engel, C, Aretz, S, Macrae, F, Winship, I, Capella, G, Nakken, S, Hovig, E, Nielsen, M, Sijmons, R H, Bertario, L, Bonanni, B, Tibiletti, M G, Cavestro, G M, Mints, M, Gluck, N, Katz, L, Heinimann, K, Vaccaro, C A, Green, K, Lalloo, F, Hill, J, Schmiegel, W, Vangala, D, Perne, C, Strauß, H-G, Tecklenburg, J, Holinski-Feder, E, Steinke-Lange, V, Mecklin, J-P, Plazzer, J-P, Pineda, M, Navarro, M, Vidal, J B, Kariv, R, Rosner, G, Piñero, T A, Kalfayan, P, Ryan, N, Ten Broeke, S W, Jenkins, M A, Sunde, L, Bernstein, I, Burn, J, Greenblatt, M, de Vos Tot Nederveen Cappel, W H, Della Valle, A, Lopez-Koestner, F, Alvarez, K, Büttner, R, Görgens, H, Morak, M, Holzapfel, S, Hüneburg, R, von Knebel Doeberitz, M, Loeffler, M, Rahner, N, Weitz, J, Pylvänäinen, K, Renkonen-Sinisalo, L, Lepistö, A, Auranen, A, Hopper, J L, Win, A K, Haile, R W, Lindor, N M, Gallinger, S, Le Marchand, L, Newcomb, P A, Figueiredo, J C, Thibodeau, S N, Therkildsen, C, Okkels, H, Ketabi, Z, Denton, O G, Rødland, E A, Vasen, H, Neffa, F, Esperon, P, Tjandra, D, Möslein, G, Sampson, J R, Evans, D G, Seppälä, T T & Møller, P 2020, ' Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants : a Prospective Lynch Syndrome Database report ', Genetics in medicine : official journal of the American College of Medical Genetics . https://doi.org/10.1038/s41436-020-01029-1
Genetics in Medicine

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, DNA Mismatch Repair, Gynecologic surgery, 0302 clinical medicine, Malalties hereditàries, Prospective Studies, Prospective cohort study, Genetics (clinical), Mismatch Repair Endonuclease PMS2, Incidence (epidemiology), Middle Aged, 16. Peace & justice, Lynch syndrome, 3. Good health, 030220 oncology & carcinogenesis, Female, syöpätaudit, MutL Protein Homolog 1, Genetic diseases, Heterozygote, medicine.medical_specialty, Salpingo-oophorectomy, Cirurgia ginecològica, Hysterectomy, Article, 03 medical and health sciences, Càncer colorectal, CAPP2, medicine, Humans, Lynchin oireyhtymä, Gynecology, perinnölliset taudit, HEREDITARY COLORECTAL-CANCER, business.industry, Endometrial cancer, Cancer, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal cancer, ASPIRIN, 030104 developmental biology, Clinical research, 3121 General medicine, internal medicine and other clinical medicine, kohdunpoisto, 3111 Biomedicine, Ovarian cancer, business

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9330a31f26a8ad6f652222a369c04f
https://research.rug.nl/en/publications/a17620ba-ac57-4302-a8cb-2039d74d0895

المؤلفون: Gabriel Capellá, Patricia Esperon, Christoph Engel, Rolf H. Sijmons, María Laura Gonzalez, Matilde Navarro, Francisco López-Köstner, Julian R. Sampson, Miquel Serra-Burriel, Karin Alvarez, Ingrid Winship, Nathan Gluck, Lone Sunde, Reinhard Büttner, Giulia Martina Cavestro, Wouter H. de Vos tot Nederveen Cappel, Jukka-Pekka Mecklin, Marc S. Greenblatt, Kate Green, Robert Hüneburg, Markus Loeffler, Maria Grazia Tibiletti, Tamara Alejandra Piñero, Florencia Neffa, Lucio Bertario, Ariadna Sánchez, Verena Steinke-Lange, Christina Therkildsen, Jane C. Figueiredo, Douglas Tjandra, Magnus von Knebel Doeberitz, Lior H. Katz, Steven Gallinger, Noralane M. Lindor, Gabriela Möslein, Adriana Della Valle, John L. Hopper, Einar Andreas Rødland, Miriam Mints, Annika Lindblom, Ian M. Frayling, Polly A. Newcomb, Pål Møller, Sanne W. ten Broeke, Laura Renkonen-Sinisalo, Sigve Nakken, Stefanie Holzapfel, Finlay A. Macrae, Stefan Aretz, Nils Rahner, Karin Wadt, Robert W. Haile, Francesc Balaguer, Revital Kariv, Stephen N. Thibodeau, Huw D. Thomas, Emma J Crosbie, Deepak Vangala, Monika Morak, Ignacio Blanco, Hans K. Schackert, Henrik Okkels, Mev Dominguez-Valentin, Oliver G. Denton, John-Paul Plazzer, Zohreh Ketabi, James Hill, Loic Le Marchand, Mark A. Jenkins, Inge Bernstein, D. Gareth Evans, Heike Görgens, Marta Pineda, John Burn, Kirsi Pylvänäinen, Eivind Hovig, Hans F. A. Vasen, Pablo Kalfayan, Toni T. Seppälä, Aung Ko Win, Maartje Nielsen, Wolff Schmiegel, Guy Rosner, Karl Heinimann, Fiona Lalloo, Carlos A. Vaccaro, Elke Holinski-Feder, Leticia Moreira

المساهمون: HUS Abdominal Center, Clinicum, II kirurgian klinikka, University of Helsinki, Department of Surgery, ATG - Applied Tumor Genomics, Research Programs Unit, Dominguez-Valentin, M., Sampson, J. R., Seppala, T. T., ten Broeke, S. W., Plazzer, J. -P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H., Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Kostner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Buttner, R., Gorgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Huneburg, R., Knebel Doeberitz, M., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvanainen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sanchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rodland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Moslein, G., Mecklin, J. -P., Nielsen, M., Moller, P., Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: Dominguez-Valentin, M, Sampson, J R, Seppälä, T T, Ten Broeke, S W, Plazzer, J-P, Nakken, S, Engel, C, Aretz, S, Jenkins, M A, Sunde, L, Bernstein, I, Capella, G, Balaguer, F, Thomas, H, Evans, D G, Burn, J, Greenblatt, M, Hovig, E, de Vos Tot Nederveen Cappel, W H, Sijmons, R H, Bertario, L, Tibiletti, M G, Cavestro, G M, Lindblom, A, Della Valle, A, Lopez-Köstner, F, Gluck, N, Katz, L H, Heinimann, K, Vaccaro, C A, Büttner, R, Görgens, H, Holinski-Feder, E, Morak, M, Holzapfel, S, Hüneburg, R, Knebel Doeberitz, M V, Loeffler, M, Rahner, N, Schackert, H K, Steinke-Lange, V, Schmiegel, W, Vangala, D, Pylvänäinen, K, Renkonen-Sinisalo, L, Hopper, J L, Win, A K, Haile, R W, Lindor, N M & Okkels, H 2020, ' Correction : Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database ', Genetics in Medicine, vol. 22, no. 9 . https://doi.org/10.1038/s41436-020-0892-4
Dominguez-Valentin, M, Sampson, J R, Seppälä, T T, Ten Broeke, S W, Plazzer, J-P, Nakken, S, Engel, C, Aretz, S, Jenkins, M A, Sunde, L, Bernstein, I, Capella, G, Balaguer, F, Thomas, H, Evans, D G, Burn, J, Greenblatt, M, Hovig, E, de Vos Tot Nederveen Cappel, W H, Sijmons, R H, Bertario, L, Tibiletti, M G, Cavestro, G M, Lindblom, A, Della Valle, A, Lopez-Köstner, F, Gluck, N, Katz, L H, Heinimann, K, Vaccaro, C A, Büttner, R, Görgens, H, Holinski-Feder, E, Morak, M, Holzapfel, S, Hüneburg, R, Knebel Doeberitz, M V, Loeffler, M, Rahner, N, Schackert, H K, Steinke-Lange, V, Schmiegel, W, Vangala, D, Pylvänäinen, K, Renkonen-Sinisalo, L, Hopper, J L, Win, A K, Haile, R W, Lindor, N M, Gallinger, S, Le Marchand, L, Newcomb, P A, Figueiredo, J C, Thibodeau, S N, Wadt, K, Therkildsen, C, Okkels, H, Ketabi, Z, Moreira, L, Sánchez, A, Serra-Burriel, M, Pineda, M, Navarro, M, Blanco, I, Green, K, Lalloo, F, Crosbie, E J, Hill, J, Denton, O G, Frayling, I M, Rødland, E A, Vasen, H, Mints, M, Neffa, F, Esperon, P, Alvarez, K, Kariv, R, Rosner, G, Pinero, T A, Gonzalez, M L, Kalfayan, P, Tjandra, D, Winship, I M, Macrae, F, Möslein, G, Mecklin, J-P, Nielsen, M & Møller, P 2020, ' Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants : findings from the Prospective Lynch Syndrome Database ', Genetics in Medicine, vol. 22, no. 1, pp. 15-25 . https://doi.org/10.1038/s41436-019-0596-9
Dipòsit Digital de la UB
Universidad de Barcelona
Evans, D G, Crosbie, E, Hill, J & et al. 2019, ' Cancer risks by gene, age and gender in 6,350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database ', Genetics in Medicine . https://doi.org/10.1038/s41436-019-0596-9
Genetics in Medicine, 22(1), 15-25. NATURE PUBLISHING GROUP
Genetics in Medicine
Dominguez-Valentin, M, Sampson, J R, Seppälä, T T, ten Broeke, S W, Plazzer, J P, Nakken, S, Engel, C, Aretz, S, Jenkins, M A, Sunde, L, Bernstein, I, Capella, G, Balaguer, F, Thomas, H, Evans, D G, Burn, J, Greenblatt, M, Hovig, E, de Vos tot Nederveen Cappel, W H, Sijmons, R H, Bertario, L, Tibiletti, M G, Cavestro, G M, Lindblom, A, Della Valle, A, Lopez-Köstner, F, Gluck, N, Katz, L H, Heinimann, K, Vaccaro, C A, Büttner, R, Görgens, H, Holinski-Feder, E, Morak, M, Holzapfel, S, Hüneburg, R, Knebel Doeberitz, M V, Loeffler, M, Rahner, N, Schackert, H K, Steinke-Lange, V, Schmiegel, W, Vangala, D, Pylvänäinen, K, Renkonen-Sinisalo, L, Hopper, J L, Win, A K, Haile, R W, Lindor, N M, Gallinger, S, Le Marchand, L, Newcomb, P A, Figueiredo, J C, Thibodeau, S N, Wadt, K, Therkildsen, C, Okkels, H, Ketabi, Z, Moreira, L, Sánchez, A, Serra-Burriel, M, Pineda, M, Navarro, M, Blanco, I, Green, K, Lalloo, F, Crosbie, E J, Hill, J, Denton, O G, Frayling, I M, Rødland, E A, Vasen, H, Mints, M, Neffa, F, Esperon, P, Alvarez, K, Kariv, R, Rosner, G, Pinero, T A, Gonzalez, M L, Kalfayan, P, Tjandra, D, Winship, I M, Macrae, F, Möslein, G, Mecklin, J P, Nielsen, M & Møller, P 2020, ' Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants : findings from the Prospective Lynch Syndrome Database ', Genetics in Medicine, vol. 22, no. 1, pp. 15-25 . https://doi.org/10.1038/s41436-019-0596-9
Genetics in Medicine, 22(1), 15-25. Nature Publishing Group

مصطلحات موضوعية: Oncology, Male, Colorectal cancer, Lynch syndrome, Penetrance, DNA Mismatch Repair, 0302 clinical medicine, Databases, Genetic, Malalties hereditàries, Prospective Studies, Càncer, PMS2, Genetics (clinical), Mismatch Repair Endonuclease PMS2, Cancer, 0303 health sciences, Sex Characteristics, Factors de risc en les malalties, 1184 Genetics, developmental biology, physiology, MLH1, Middle Aged, 16. Peace & justice, 3. Good health, DNA-Binding Proteins, MutS Homolog 2 Protein, syöpägeenit, MSH2, 030220 oncology & carcinogenesis, MSH6, 030211 gastroenterology & hepatology, DNA mismatch repair, Female, geneettiset tekijät, MutL Protein Homolog 1, Genetic diseases, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Risk factors in diseases, suolistosyövät, MUTATION CARRIERS, Risk Assessment, Article, sukupuoli, Age and gender, 03 medical and health sciences, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Lynchin oireyhtymä, Gene, 030304 developmental biology, Aged, business.industry, Endometrial cancer, Correction, nutritional and metabolic diseases, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Survival Analysis, digestive system diseases, Mutation, 3111 Biomedicine, ikä, business, Ovarian cancer

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347fa11199294fa0eb757b6ff6ba0788
https://vbn.aau.dk/ws/files/394936730/Correction_Dominguez_Valentin_et_al._2020_.pdf

المؤلفون: Karl Heinimann, Ian Tomlinson, Rui Henrique, Helena Baldaia, Fátima Carneiro, Michal Kovac, Ana Peixoto, Manuela Pinheiro, Manuel R. Teixeira, Paula Lopes, Isabel Veiga, Raquel Seruca, Carla M. A. Pinto

المصدر: British Journal of Cancer

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Adolescent, Carcinogenesis, Activin Receptors, Type II, Protein Serine-Threonine Kinases, Biology, Bone Morphogenetic Protein Receptors, Type II, Genetics & Genomics, MLH1, Young Adult, Germline mutation, medicine, Humans, neoplasms, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Aged, Genetics, Receptor, Transforming Growth Factor-beta Type II, Nuclear Proteins, nutritional and metabolic diseases, Microsatellite instability, Middle Aged, 16. Peace & justice, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, target genes, digestive system diseases, Lynch syndrome, 3. Good health, DNA-Binding Proteins, MSH6, MutS Homolog 2 Protein, Oncology, MSH3, MSH2, MutS Homolog 3 Protein, Female, microsatellite instability, DNA mismatch repair, Colorectal Neoplasms, MutL Protein Homolog 1, Receptors, Transforming Growth Factor beta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409578b8174017856f53ef8a15fa37cd
https://doi.org/10.1038/bjc.2015.281

المؤلفون: Päivi Peltomäki, Karl Heinimann, Jian Zhang, Hansjakob Mueller, Anna Russell, Annette Lindroos, Saara Ollila, Martina Plasilova, Giancarlo Marra

المصدر: Cancer Research. 66:659-664

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Mitotic crossover, DNA Mutational Analysis, Gene Conversion, Gene Dosage, Loss of Heterozygosity, Biology, medicine.disease_cause, MLH1, Loss of heterozygosity, Germline mutation, medicine, Humans, Genetic Predisposition to Disease, neoplasms, Finland, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Aged, Genetics, Gene Expression Profiling, Nuclear Proteins, nutritional and metabolic diseases, Cancer, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Cell Transformation, Neoplastic, MutS Homolog 2 Protein, Oncology, MSH2, Cancer research, Female, DNA mismatch repair, Carrier Proteins, MutL Protein Homolog 1, Carcinogenesis, Gene Deletion, Switzerland, Microsatellite Repeats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1964d30c3eccf8fd760b7d0b233c571d
https://doi.org/10.1158/0008-5472.can-05-4043

المؤلفون: Jian Zhang, Martina Plasilova, Giancarlo Marra, Karl Heinimann, Markus Mettler, Hansjakob Mueller, Roberta Okhowat

المصدر: Genes, Chromosomes and Cancer. 45:1106-1110

مصطلحات موضوعية: Adult, Male, Cancer Research, Colorectal cancer, Germline mosaicism, Adenocarcinoma, Biology, Gene mutation, MLH1, Germline mutation, Genetics, medicine, Humans, Family, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Nuclear Proteins, Middle Aged, medicine.disease, medicine.anatomical_structure, MSH2, Female, DNA mismatch repair, Carrier Proteins, Colorectal Neoplasms, MutL Protein Homolog 1, Germ cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb37fa61f8656b2e1271059e4a34562
https://doi.org/10.1002/gcc.20374

المؤلفون: Nina Mojas, Petr Cejka, Karl Heinimann, Lovorka Stojic, Anna Russell, Elda Cannavo, Massimiliano di Pietro, Josef Jiricny, Giancarlo Marra

المساهمون: University of Zurich, Jiricny, J

المصدر: The EMBO Journal. 22:2245-2254

مصطلحات موضوعية: G2 Phase, Alkylating Agents, Methylnitronitrosoguanidine, congenital, hereditary, and neonatal diseases and abnormalities, Cell cycle checkpoint, DNA Repair, Base Pair Mismatch, DNA repair, Mitosis, Genetics and Molecular Biology, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, chemistry.chemical_compound, 1300 General Biochemistry, Genetics and Molecular Biology, 2400 General Immunology and Microbiology, 1312 Molecular Biology, medicine, Humans, neoplasms, Molecular Biology, Adaptor Proteins, Signal Transducing, General Immunology and Microbiology, General Neuroscience, 10061 Institute of Molecular Cancer Research, HEK 293 cells, Nuclear Proteins, 2800 General Neuroscience, Microsatellite instability, Articles, Mismatch Repair Protein, DNA Methylation, medicine.disease, Molecular biology, digestive system diseases, Neoplasm Proteins, chemistry, General Biochemistry, DNA methylation, 570 Life sciences, biology, DNA mismatch repair, Carrier Proteins, MutL Protein Homolog 1

وصف الملف: cdg216.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b536254d3ec5172c999785c0d9d99883
https://doi.org/10.1093/emboj/cdg216

المؤلفون: Pierre Hutter, Karl Heinimann, Hynek Bachraty, Ian Tomlinson, Denisa Ilencikova, Zdena Bartosova, Katarína Bachratá, Salvatore Piscuoglio, Benno Roethlisberger, Michal Kovac, Monika Kovacova

المصدر: Human mutation. 36(2)

مصطلحات موضوعية: Somatic cell, Adenomatous Polyposis Coli Protein, Biology, Genome, Germline, chemistry.chemical_compound, Chromosome Breakpoints, Antigens, Neoplasm, Genetics, Homologous chromosome, Humans, Homologous Recombination, Genetics (clinical), Sequence (medicine), Adaptor Proteins, Signal Transducing, Mismatch Repair Endonuclease PMS2, Adenosine Triphosphatases, Base Sequence, fungi, Breakpoint, Chromosome Mapping, Nuclear Proteins, Molecular Sequence Annotation, Sequence Analysis, DNA, Epithelial Cell Adhesion Molecule, Colorectal Neoplasms, Hereditary Nonpolyposis, DNA-Binding Proteins, DNA Repair Enzymes, MutS Homolog 2 Protein, chemistry, Adenomatous Polyposis Coli, Homologous recombination, MutL Protein Homolog 1, Cell Adhesion Molecules, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2e559c1b0d6ca52524f537bbd50d0a
https://pubmed.ncbi.nlm.nih.gov/25418510

المؤلفون: Marcel Kool, Jan Koster, Karl Heinimann, Michael A. Grotzer, André Fedier, Christian Hagel, Torsten Pietsch, Stefan Rutkowski, Manny D. Bacolod, Henry S. Friedman, A. O. von Bueren, Giancarlo Marra, Uwe Kordes

المساهمون: Oncogenomics, Other departments, University of Zurich, von Bueren, A O

المصدر: British journal of cancer, 107(8), 1399-1408. Nature Publishing Group
British Journal of Cancer

مصطلحات موضوعية: Male, Cancer Research, Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, DNA repair, Dacarbazine, Drug resistance, temozolomide, Biology, medulloblastoma, DNA Mismatch Repair, O(6)-Methylguanine-DNA Methyltransferase, Cell Line, Tumor, medicine, Humans, 1306 Cancer Research, Cerebellar Neoplasms, Child, Antineoplastic Agents, Alkylating, DNA Modification Methylases, neoplasms, Adaptor Proteins, Signal Transducing, Medulloblastoma, Temozolomide, drug resistance, Tumor Suppressor Proteins, 10061 Institute of Molecular Cancer Research, O-6-methylguanine-DNA methyltransferase, Nuclear Proteins, Cerebellar Neoplasm, Genetics and Genomics, medicine.disease, digestive system diseases, nervous system diseases, stomatognathic diseases, mismatch repair, DNA Repair Enzymes, Oncology, Drug Resistance, Neoplasm, Child, Preschool, Cancer research, 570 Life sciences, biology, DNA mismatch repair, Female, 2730 Oncology, MutL Protein Homolog 1, medicine.drug

وصف الملف: bjc2012403a.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d4e8982b64daea105435bdf63abd4
https://pure.amc.nl/en/publications/mismatch-repair-deficiency-a-temozolomide-resistance-factor-in-medulloblastoma-cell-lines-that-is-uncommon-in-primary-medulloblastoma-tumours(dbaf08e0-4ec2-43bc-a4f6-c0d2fd8344c2).html

المؤلفون: Hansjakob Mueller, Lucienne Gautier, Mauro Buser, Karl Heinimann, Giancarlo Marra, Nicole Buerki, Michal Kovac

المصدر: Genes, chromosomescancer. 51(1)

مصطلحات موضوعية: Oncology, Adult, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, Heterozygote, Breast Neoplasms, Biology, MLH1, DNA Mismatch Repair, Breast cancer, Germline mutation, Internal medicine, Neoplasms, Genetics, medicine, Humans, neoplasms, Germ-Line Mutation, Adaptor Proteins, Signal Transducing, Aged, Incidence, nutritional and metabolic diseases, Microsatellite instability, Cancer, Nuclear Proteins, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Lynch syndrome, MutS Homolog 2 Protein, MSH2, Female, Ovarian cancer, MutL Protein Homolog 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0e0f54c174ed62cdf93a385a67ac17
https://pubmed.ncbi.nlm.nih.gov/22034109

المؤلفون: Giancarlo Marra, Josef Jiricny, Denisa Ilencikova, Tomas Krivulcik, Bujalkova M, Brigitte Wolf, Karl Heinimann, Katarina Zavodna, Zdena Bartosova, Michal Kovac, Judith Karner-Hanusch

المصدر: Clinical chemistry. 54(11)

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA Repair, Genotype, Base Pair Mismatch, Clinical Biochemistry, Loss of Heterozygosity, Biology, MLH1, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Sensitivity and Specificity, Loss of heterozygosity, Germline mutation, Humans, Multiplex, neoplasms, Genotyping, Adaptor Proteins, Signal Transducing, DNA Primers, Genetics, Base Sequence, Biochemistry (medical), nutritional and metabolic diseases, Nuclear Proteins, Molecular biology, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, MutS Homolog 2 Protein, MSH2, MutL Protein Homolog 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510f107bbe4cd97a30686e41edb50808
https://pubmed.ncbi.nlm.nih.gov/18772310