نتائج البحث - "Elgene Lim"

المصدر: Nature Communications
Alves, C L, Ehmsen, S, Terp, M G, Portman, N, Tuttolomondo, M, Gammelgaard, O L, Hundebøl, M F, Kaminska, K, Johansen, L E, Bak, M, Honeth, G, Bosch, A, Lim, E & Ditzel, H J 2021, ' Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer ', Nature Communications, vol. 12, 5112 . https://doi.org/10.1038/s41467-021-25422-9
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Fulvestrant/administration & dosage, endocrine system diseases, medicine.drug_class, Science, General Physics and Astronomy, Breast Neoplasms, Proto-Oncogene Proteins c-akt/genetics, Article, General Biochemistry, Genetics and Molecular Biology, Metastasis, Breast cancer, Breast Neoplasms/drug therapy, Cell Line, Tumor, Medicine, Humans, Molecular Targeted Therapy, neoplasms, Protein kinase B, Fulvestrant, Protein Kinase Inhibitors, Multidisciplinary, integumentary system, business.industry, Protein Kinase Inhibitors/administration & dosage, Endocrine therapy, Cancer, Cyclin-Dependent Kinase 4, General Chemistry, Cyclin-Dependent Kinase 6, Cyclin-Dependent Kinase 6/antagonists & inhibitors, Translational research, medicine.disease, Publisher Correction, Cyclin-Dependent Kinase 4/antagonists & inhibitors, Estrogen, Tumor progression, Drug Resistance, Neoplasm, Cancer research, Disease Progression, Drug Therapy, Combination, Female, biological phenomena, cell phenomena, and immunity, business, Proto-Oncogene Proteins c-akt, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909c54d06c561d241308a49e7f7f6e84
https://pubmed.ncbi.nlm.nih.gov/34531405

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7

Targeting CDK2 in cancer: challenges and opportunities for therapy

المؤلفون: Neil Portman, Solomon Tadesse, Shudong Wang, C. Elizabeth Caldon, Abel Tesfaye Anshabo, Wayne D. Tilley, Elgene Lim

المساهمون: Tadesse, Solomon, Anshabo, Abel T, Portman, Neil, Lim, Elgene, Tilley, Wayne, Caldon, C Elizabeth, Wang, Shudong

المصدر: Drug discovery today. 25(2)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cb909d2d99af6248b05fbf0ad59301
https://pubmed.ncbi.nlm.nih.gov/31839441

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Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

المصدر: Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-17 (2019)

مصطلحات موضوعية: MAPK/ERK pathway, Receptor, ErbB-2, Fluorescent Antibody Technique, Breast Neoplasms, Antibodies, Monoclonal, Humanized, Lapatinib, lcsh:RC254-282, Receptor tyrosine kinase, Mice, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Cell Line, Tumor, Receptor tyrosine kinases, medicine, Animals, Humans, ERBB3, Phosphorylation, ERBB2, skin and connective tissue diseases, Protein Kinase Inhibitors, neoplasms, PI3K/AKT/mTOR pathway, Pertuzumab, Dose-Response Relationship, Drug, biology, Kinase, Cell growth, Chemistry, Trastuzumab, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Xenograft Model Antitumor Assays, 3. Good health, Disease Models, Animal, Heterodimers, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Protein Multimerization, Signal Transduction, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b89b30d561873fa9e54ee4aacf7cd73
https://doi.org/10.1186/s13058-019-1127-y

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9

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

المؤلفون: Aron Charles Eklund, Manish Neupane, Allison P. Clark, Steven E. Schumacher, Daniel P. Silver, Rameen Beroukhim, David E. Hill, Elgene Lim, Marc Vidal, Aedín C. Culhane, Nicolai Juul Birkbak, William T. Barry, Zoltan Szallasi, Serena Landini

المصدر: Neupane, M, Clark, A P, Landini, S, Birkbak, N J, Eklund, A C, Lim, E, Culhane, A C, Barry, W T, Schumacher, S E, Beroukhim, R, Szallasi, Z I, Vidal, M, Hill, D E & Silver, D P 2016, ' MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy ', Cancer Discovery, vol. 6, no. 1, pp. 45-58 . https://doi.org/10.1158/2159-8290.cd-15-0341

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, congenital, hereditary, and neonatal diseases and abnormalities, Methyl-CpG-Binding Protein 2, medicine.medical_treatment, Biology, medicine.disease_cause, Article, Epigenesis, Genetic, Cytosine, Mice, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Neoplasms, mental disorders, medicine, Animals, Humans, Protein Isoforms, Epigenetics, Oncogene, Growth factor, Gene Amplification, Cancer, medicine.disease, nervous system diseases, Alternative Splicing, 030104 developmental biology, Oncology, 5-Methylcytosine, ras Proteins, Cancer research, KRAS, Signal transduction, Neoplasm Transplantation, Epigenetic therapy, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fef4caecc283ec48cfa7da43d96d3e3
https://doi.org/10.1158/2159-8290.cd-15-0341

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Secreted Tumor Antigens - Immune Biomarkers for Diagnosis and Therapy

المؤلفون: Elgene Lim, Suresh Mathivanan, Els N.T. Meeusen

المصدر: PROTEOMICS. 17:1600442

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13244cf9c7734e7730c0e1fdbf0b325f
https://doi.org/10.1002/pmic.201600442

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