المؤلفون: Kim KR; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Cho EJ; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Eom JW; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Oh SS; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Nakamura T; Neurodegeneration New Medicines Center, Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA, 92037, USA., Oh CK; Neurodegeneration New Medicines Center, Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA, 92037, USA., Lipton SA; Neurodegeneration New Medicines Center, Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA, 92037, USA. slipton@scripps.edu.; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA, 92093, USA. slipton@scripps.edu., Kim YH; Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea. yhkim@sejong.ac.kr.

المصدر: Cell death and differentiation [Cell Death Differ] 2022 Nov; Vol. 29 (11), pp. 2137-2150. Date of Electronic Publication: 2022 Apr 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases*/genetics , Alzheimer Disease*/metabolism, Animals ; Humans ; Mice ; Cathepsin B ; Protein Aggregates ; Proteins/metabolism ; Cysteine ; Nitric Oxide

المؤلفون: Nakamura T; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, California, USA., Oh CK; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, California, USA., Zhang X; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, California, USA., Tannenbaum SR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Lipton SA; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, California, USA.; Department of Neurosciences, University of California San Diego School of Medicine, La Jolla, California, USA.

المصدر: Antioxidants & redox signaling [Antioxid Redox Signal] 2021 Sep 01; Vol. 35 (7), pp. 531-550. Date of Electronic Publication: 2021 Jun 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases*/metabolism, Humans ; Nitric Oxide/metabolism ; Oxidation-Reduction ; Protein Processing, Post-Translational ; Reactive Nitrogen Species/metabolism ; Signal Transduction

المؤلفون: Nakamura T; Neurodegeneration New Medicines Center and Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA. Electronic address: tnakamura@scripps.edu., Oh CK; Neurodegeneration New Medicines Center and Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA., Zhang X; Neurodegeneration New Medicines Center and Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA., Lipton SA; Neurodegeneration New Medicines Center and Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA; Department of Neurosciences, University of California San Diego, School of Medicine, La Jolla, CA, 92093, USA. Electronic address: slipton@scripps.edu.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2021 Aug 20; Vol. 172, pp. 562-577. Date of Electronic Publication: 2021 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases*/genetics , Protein Folding*, Humans ; Nitric Oxide ; Oxidation-Reduction ; Proteostasis Deficiencies

المؤلفون: Ghatak S; Department of Molecular Medicine and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California 92037, USA; email: slipton@scripps.edu., Talantova M; Department of Molecular Medicine and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California 92037, USA; email: slipton@scripps.edu., McKercher SR; Department of Molecular Medicine and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California 92037, USA; email: slipton@scripps.edu., Lipton SA; Department of Molecular Medicine and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California 92037, USA; email: slipton@scripps.edu.; Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

المصدر: Annual review of pharmacology and toxicology [Annu Rev Pharmacol Toxicol] 2021 Jan 06; Vol. 61, pp. 701-721. Date of Electronic Publication: 2020 Sep 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Annual Reviews Country of Publication: United States NLM ID: 7607088 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-4304 (Electronic) Linking ISSN: 03621642 NLM ISO Abbreviation: Annu Rev Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Autism Spectrum Disorder* , Neurodegenerative Diseases*, Brain ; Humans ; Neurons

المؤلفون: Nakamura T; Departments of Molecular Medicine and Neuroscience, Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California., Lipton SA; Departments of Molecular Medicine and Neuroscience, Neuroscience Translational Center, The Scripps Research Institute, La Jolla, California.; Department of Neurosciences, University of California San Diego, School of Medicine, La Jolla, California.

المصدر: Antioxidants & redox signaling [Antioxid Redox Signal] 2020 Apr 20; Vol. 32 (12), pp. 817-833. Date of Electronic Publication: 2019 Dec 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

مواضيع طبية MeSH: Mitochondria/*metabolism , Neurodegenerative Diseases/*metabolism , Nitric Oxide/*metabolism, Animals ; Humans ; Protein Processing, Post-Translational ; Reactive Nitrogen Species/metabolism ; Reactive Oxygen Species/metabolism

المؤلفون: Connolly NMC; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Theurey P; Department of Biomedical Sciences, University of Padova, Padova, Italy., Adam-Vizi V; Department of Medical Biochemistry, Semmelweis University, Budapest, Hungary., Bazan NG; Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, 70112, USA., Bernardi P; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Neuroscience Institute, National Research Council (CNR), Padova, Italy., Bolaños JP; University of Salamanca, CIBERFES, Institute of Functional Biology and Genomics (IBFG), CSIC, 37007, Salamanca, Spain., Culmsee C; Institute of Pharmacology and Clinical Pharmacy, University of Marburg, 35043, Marburg, Germany., Dawson VL; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Adrienne Helis Malvin Medical Research Foundation, Diana Helis Henry Medical Research Foundation, New Orleans, LA, 70130, USA., Deshmukh M; Neuroscience Center, University of North Carolina, Chapel Hill, USA., Duchen MR; Department of Cell and Developmental Biology and Consortium for Mitochondrial Research, University College London, London, WC1E 6BT, UK., Düssmann H; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Fiskum G; Department of Anesthesiology and Center for Shock, Trauma and Anesthesiology Research (STAR), University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, USA., Galindo MF; Unidad de Neuropsicofarmacología Translacional, Complejo Hospitalario Universitario de Albacete, Albacete, Spain., Hardingham GE; UK Dementia Research Institute at the University of Edinburgh, Edinburgh Medical School, Edinburgh, EH8 9XD, UK., Hardwick JM; Department of Molecular Microbiology and Immunology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, 21205, USA., Jekabsons MB; Department of Biology, University of Mississippi, University, MS, 38677, USA., Jonas EA; Department of Internal Medicine, Section of Endocrinology, Yale University, New Haven, CT, USA., Jordán J; Department of Medical Science-Pharmacology, University of Castilla-La Mancha, Albacete, Spain., Lipton SA; Neuroscience Translational Center and Depts. of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA, 92037, USA.; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA, 92121, USA.; Department of Neurosciences, University of California San Diego, School of Medicine, La Jolla, CA, 92093, USA., Manfredi G; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, 10065, USA., Mattson MP; National Institute on Aging Intramural Research Program, Baltimore, MD, USA., McLaughlin B; Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA., Methner A; University Medical Center Mainz, Dept. of Neurology, Mainz, Germany., Murphy AN; Department of Pharmacology, University of California, San Diego, CA, 92093, USA., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., Nicholls DG; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Polster BM; Department of Anesthesiology and Center for Shock, Trauma and Anesthesiology Research (STAR), University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, USA., Pozzan T; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Neuroscience Institute, National Research Council (CNR), Padova, Italy., Rizzuto R; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Neuroscience Institute, National Research Council (CNR), Padova, Italy., Satrústegui J; Dpto. de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, 28049, Madrid, Spain., Slack RS; Brain & Mind Research Institute, University of Ottawa, Ontario, K1H 8M5, Canada., Swanson RA; Department of Neurology, University of California San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, CA, 94121, USA., Swerdlow RH; The University of Kansas Alzheimer's Disease Center and Depts. of Neurology, Molecular and Integrative Physiology, and Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Will Y; Pfizer, Groton, CT, 06340, USA., Ying Z; Laboratory of Cellular and Molecular Neuropharmacology, Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, 215021, China., Joselin A; Brain & Mind Research Institute, University of Ottawa, Ontario, K1H 8M5, Canada., Gioran A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Moreira Pinho C; Center for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Watters O; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Salvucci M; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Llorente-Folch I; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Park DS; Brain & Mind Research Institute, University of Ottawa, Ontario, K1H 8M5, Canada., Bano D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Ankarcrona M; Center for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Pizzo P; Department of Biomedical Sciences, University of Padova, Padova, Italy.; Neuroscience Institute, National Research Council (CNR), Padova, Italy., Prehn JHM; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland. prehn@rcsi.ie.

المصدر: Cell death and differentiation [Cell Death Differ] 2018 Mar; Vol. 25 (3), pp. 542-572. Date of Electronic Publication: 2017 Dec 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ

مواضيع طبية MeSH: Models, Biological*, Mitochondria/*metabolism , Mitochondria/*pathology , Neurodegenerative Diseases/*metabolism , Neurodegenerative Diseases/*pathology, Animals ; Humans

المؤلفون: Nakamura T; Neuroscience Translational Center, and Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA. Electronic address: tnakamura@scripps.edu., Lipton SA; Neuroscience Translational Center, and Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA; Department of Neurosciences, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA. Electronic address: slipton@scripps.edu.

المصدر: Trends in endocrinology and metabolism: TEM [Trends Endocrinol Metab] 2017 Dec; Vol. 28 (12), pp. 879-892. Date of Electronic Publication: 2017 Oct 30.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Pub. Co Country of Publication: United States NLM ID: 9001516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3061 (Electronic) Linking ISSN: 10432760 NLM ISO Abbreviation: Trends Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Mitochondria/*metabolism , Neurodegenerative Diseases/*metabolism, Animals ; Citric Acid Cycle/physiology ; Electron Transport/physiology ; Energy Metabolism/physiology ; Humans ; Oxidation-Reduction

المؤلفون: Nakamura T; Scintillon Institute, San Diego, CA 92121, USA. Electronic address: tnakamura@scintillon.org., Lipton SA; Scintillon Institute, San Diego, CA 92121, USA; Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, CA 92039, USA. Electronic address: slipton@ucsd.edu.

المصدر: Trends in pharmacological sciences [Trends Pharmacol Sci] 2016 Jan; Vol. 37 (1), pp. 73-84. Date of Electronic Publication: 2015 Dec 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Published By Elsevier In Association With The International Union Of Pharmacology Country of Publication: England NLM ID: 7906158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3735 (Electronic) Linking ISSN: 01656147 NLM ISO Abbreviation: Trends Pharmacol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases/*metabolism , Nitric Oxide/*metabolism , Receptors, N-Methyl-D-Aspartate/*metabolism, Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism ; Humans ; Nitrosation ; Protein Processing, Post-Translational ; Reactive Nitrogen Species/metabolism ; S-Nitrosothiols/metabolism ; Second Messenger Systems

المؤلفون: Nakamura T; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Prikhodko OA; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA; Biomedical Sciences Graduate Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Pirie E; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA; Biomedical Sciences Graduate Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA., Nagar S; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA; Graduate School of Biomedical Sciences, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Akhtar MW; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Oh CK; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., McKercher SR; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Ambasudhan R; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Okamoto S; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Lipton SA; Neuroscience and Aging Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA; Biomedical Sciences Graduate Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Neurosciences, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: slipton@ucsd.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2015 Dec; Vol. 84, pp. 99-108. Date of Electronic Publication: 2015 Mar 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Neurodegenerative Diseases/*metabolism , Protein S/*metabolism, Animals ; Humans

المؤلفون: Nakamura T; Del E. Web Center for Neuroscience, Aging, and Stem Cell Research, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. tnakamura@sanfordburnham.org, Tu S, Akhtar MW, Sunico CR, Okamoto S, Lipton SA

المصدر: Neuron [Neuron] 2013 May 22; Vol. 78 (4), pp. 596-614.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*metabolism , Nerve Tissue Proteins/*metabolism , Neurodegenerative Diseases/*metabolism , Reactive Nitrogen Species/*metabolism, Animals ; Brain/pathology ; Humans ; Neurodegenerative Diseases/pathology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism