المؤلفون: Remigio GJ; Interdepartmental Neuroscience Program, University of Utah, Salt Lake City, UT 84108-1210, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108-1210, USA., Loewen JL; Interdepartmental Neuroscience Program, University of Utah, Salt Lake City, UT 84108-1210, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108-1210, USA., Heuston S; The Waterford School, Sandy, UT 84093-2902, USA., Helgeson C; Juan Diego Catholic High School, Draper, UT 84020-9035, USA., White HS; Interdepartmental Neuroscience Program, University of Utah, Salt Lake City, UT 84108-1210, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108-1210, USA; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT 84108-1210, USA., Wilcox KS; Interdepartmental Neuroscience Program, University of Utah, Salt Lake City, UT 84108-1210, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108-1210, USA; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT 84108-1210, USA., West PJ; Interdepartmental Neuroscience Program, University of Utah, Salt Lake City, UT 84108-1210, USA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108-1210, USA; Anticonvulsant Drug Development Program, University of Utah, Salt Lake City, UT 84108-1210, USA. Electronic address: peter.west@utah.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2017 Sep; Vol. 105, pp. 221-234. Date of Electronic Publication: 2017 Jun 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Dentate Gyrus/*pathology , Excitatory Postsynaptic Potentials/*physiology , Memory Disorders/*etiology , Neurons/*pathology , Seizures/*complications , Seizures/*pathology, Animals ; Association Learning ; Biophysics ; Cell Death/physiology ; Cornea/innervation ; Disease Models, Animal ; Electric Stimulation ; Glial Fibrillary Acidic Protein/metabolism ; Gliosis/etiology ; In Vitro Techniques ; Kindling, Neurologic/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Patch-Clamp Techniques ; Phosphopyruvate Hydratase/metabolism ; Synapses/physiology

المؤلفون: Loewen JL; From the Interdepartmental Program in Neuroscience (JLL, HSW, KSW); HHMI Med into Grad Program (JLL); Department of Pharmacology and Toxicology (JLL, MLB-H, EJD, HSW, KSW); and Anticonvulsant Drug Development Program (MLB-H, EJD, HSW, KSW), University of Utah, Salt Lake City, Utah, USA., Barker-Haliski ML; From the Interdepartmental Program in Neuroscience (JLL, HSW, KSW); HHMI Med into Grad Program (JLL); Department of Pharmacology and Toxicology (JLL, MLB-H, EJD, HSW, KSW); and Anticonvulsant Drug Development Program (MLB-H, EJD, HSW, KSW), University of Utah, Salt Lake City, Utah, USA., Dahle EJ; From the Interdepartmental Program in Neuroscience (JLL, HSW, KSW); HHMI Med into Grad Program (JLL); Department of Pharmacology and Toxicology (JLL, MLB-H, EJD, HSW, KSW); and Anticonvulsant Drug Development Program (MLB-H, EJD, HSW, KSW), University of Utah, Salt Lake City, Utah, USA., White HS; From the Interdepartmental Program in Neuroscience (JLL, HSW, KSW); HHMI Med into Grad Program (JLL); Department of Pharmacology and Toxicology (JLL, MLB-H, EJD, HSW, KSW); and Anticonvulsant Drug Development Program (MLB-H, EJD, HSW, KSW), University of Utah, Salt Lake City, Utah, USA., Wilcox KS; From the Interdepartmental Program in Neuroscience (JLL, HSW, KSW); HHMI Med into Grad Program (JLL); Department of Pharmacology and Toxicology (JLL, MLB-H, EJD, HSW, KSW); and Anticonvulsant Drug Development Program (MLB-H, EJD, HSW, KSW), University of Utah, Salt Lake City, Utah, USA. karen.wilcox@hsc.utah.edu.

المصدر: Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2016 Apr; Vol. 75 (4), pp. 366-78. Date of Electronic Publication: 2016 Mar 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985192R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-6578 (Electronic) Linking ISSN: 00223069 NLM ISO Abbreviation: J Neuropathol Exp Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Cell Proliferation/*physiology , Epilepsy, Temporal Lobe/*complications , Gliosis/*etiology , Neuroglia/*pathology , Neurons/*pathology, Animals ; Calcium-Binding Proteins/metabolism ; Cardiovirus Infections/complications ; Epilepsy, Temporal Lobe/pathology ; Epilepsy, Temporal Lobe/virology ; Fluoresceins/metabolism ; Ki-67 Antigen/metabolism ; Kindling, Neurologic/physiology ; Mice ; Mice, Inbred C57BL ; Microfilament Proteins/metabolism ; Microscopy, Confocal ; Nerve Tissue Proteins/metabolism ; Theilovirus/pathogenicity

المؤلفون: Walls AB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark. Electronic address: abw@sund.ku.dk., Flynn SP; Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 417 Wakara Way, Suite 3211, Salt Lake City, UT 84108, USA., West PJ; Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 417 Wakara Way, Suite 3211, Salt Lake City, UT 84108, USA., Müller MS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK., Bak LK; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark., Bulaj G; University of Utah, Department Medicinal Chemistry, College of Pharmacy, 30 S 2000 E RM 201, Salt Lake City, UT 84112, USA., Schousboe A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark., White HS; Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 417 Wakara Way, Suite 3211, Salt Lake City, UT 84108, USA.

المصدر: Epilepsy research [Epilepsy Res] 2016 Mar; Vol. 121, pp. 55-63. Date of Electronic Publication: 2016 Jan 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6844 (Electronic) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Excitatory Postsynaptic Potentials/*drug effects , Galanin/*analogs & derivatives , Inhibitory Postsynaptic Potentials/*drug effects , Lipopeptides/*pharmacology , Neurons/*drug effects , Neurotransmitter Agents/*metabolism, Animals ; Animals, Newborn ; Brain/cytology ; Cell Survival/drug effects ; Cells, Cultured ; Excitatory Amino Acid Agonists/pharmacology ; Female ; Galanin/pharmacology ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred C57BL ; N-Methylaspartate/pharmacology ; Organ Culture Techniques ; Pregnancy ; Time Factors ; Vitamin K/analogs & derivatives ; Vitamin K/pharmacology

المؤلفون: Poulsen CF; Department of Pharmacology and Pharmacotherapy, Danish University of Pharmaceutical Sciences, Copenhagen, DK, Denmark., Schousboe I, Sarup A, White HS, Schousboe A

المصدر: Neurochemistry international [Neurochem Int] 2006 May-Jun; Vol. 48 (6-7), pp. 657-61. Date of Electronic Publication: 2006 Mar 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0197-0186 (Print) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Astrocytes/*drug effects , Bucladesine/*pharmacology , Excitatory Amino Acid Transporter 1/*biosynthesis , Excitatory Amino Acid Transporter 2/*biosynthesis , Fructose/*analogs & derivatives , Neurons/*drug effects, Animals ; Animals, Newborn ; Astrocytes/cytology ; Astrocytes/metabolism ; Carbazoles/pharmacology ; Cells, Cultured ; Coculture Techniques ; Embryo, Mammalian/cytology ; Enzyme Activators/pharmacology ; Fructose/pharmacology ; Indoles ; Maleimides ; Mice ; Neurons/cytology ; Neurons/metabolism ; Protein Kinase C/antagonists & inhibitors ; Tetradecanoylphorbol Acetate/pharmacology ; Topiramate

المؤلفون: Otto JF; Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA., Yang Y, Frankel WN, White HS, Wilcox KS

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2006 Feb 15; Vol. 26 (7), pp. 2053-9.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Hippocampus/*physiology , KCNQ2 Potassium Channel/*genetics , Neurons/*physiology , Pyramidal Cells/*physiology, Animals ; Female ; In Vitro Techniques ; KCNQ2 Potassium Channel/physiology ; Mice ; Mice, Inbred C57BL ; Oocytes/physiology ; Seizures/physiopathology ; Transfection ; Xenopus/physiology

المؤلفون: Poulsen CF; Department of Pharmacology, The Danish University of Pharmaceutical Sciences, Copenhagen, Denmark., Simeone TA, Maar TE, Smith-Swintosky V, White HS, Schousboe A

المصدر: Neurochemical research [Neurochem Res] 2004 Jan; Vol. 29 (1), pp. 275-82.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print Cited Medium: Print ISSN: 0364-3190 (Print) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

مواضيع طبية MeSH: Calcium/*metabolism , Cerebellum/*drug effects , Cerebral Cortex/*drug effects , Fructose/*analogs & derivatives , Fructose/*pharmacology , Hippocampus/*drug effects , Kainic Acid/*pharmacology , Neurons/*drug effects , alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*pharmacology, Animals ; Cerebellum/cytology ; Cerebellum/metabolism ; Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; Female ; Hippocampus/cytology ; Hippocampus/metabolism ; Ion Transport ; Mice ; Neurons/metabolism ; Pregnancy ; Topiramate

المؤلفون: White HS; Anticonvulsant Screening Project, Department of Pharmacology and Toxicology, University of Utah, 20 S. 2030 E, Room 408, Salt Lake City, UT 84112, USA. swhite@hsc.utah.edu, Sarup A, Bolvig T, Kristensen AS, Petersen G, Nelson N, Pickering DS, Larsson OM, Frølund B, Krogsgaard-Larsen P, Schousboe A

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2002 Aug; Vol. 302 (2), pp. 636-44.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Membrane Transport Proteins* , Organic Anion Transporters*, Anticonvulsants/*pharmacology , Astrocytes/*metabolism , Carrier Proteins/*metabolism , Isoxazoles/*pharmacology , Membrane Proteins/*metabolism , Neuroglia/*metabolism , Neurons/*metabolism , gamma-Aminobutyric Acid/*pharmacokinetics, Alkylation ; Animals ; Animals, Newborn ; Biological Transport ; Carrier Proteins/antagonists & inhibitors ; Cells, Cultured ; Female ; GABA Plasma Membrane Transport Proteins ; Kinetics ; Male ; Membrane Proteins/antagonists & inhibitors ; Mice ; Mice, Inbred Strains ; Prefrontal Cortex/cytology ; Prefrontal Cortex/physiology ; Structure-Activity Relationship

المؤلفون: Skradski S; Anticonvulsant Screening Project, Department of Pharmacology and Toxicology, University of Utah, College of Pharmacy, Salt Lake City 84112, USA., White HS

المصدر: Epilepsia [Epilepsia] 2000; Vol. 41 (S1), pp. 45-7.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print Cited Medium: Print ISSN: 0013-9580 (Print) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Cobalt/*metabolism , Fructose/*analogs & derivatives , Kainic Acid/*pharmacology , Neurons/*drug effects , Neurons/*metabolism , Receptors, Glutamate/*drug effects, Animals ; Calcium/metabolism ; Cations, Divalent ; Cells, Cultured ; Cerebellum/cytology ; Cerebellum/drug effects ; Cerebellum/metabolism ; Excitatory Amino Acid Antagonists/pharmacology ; Fructose/pharmacology ; Magnesium/metabolism ; Mice ; Quinoxalines/pharmacology ; Receptors, AMPA/drug effects ; Receptors, AMPA/metabolism ; Receptors, Glutamate/metabolism ; Receptors, Kainic Acid/drug effects ; Receptors, Kainic Acid/metabolism ; Topiramate

المؤلفون: White HS; Anticonvulsant Screening Project, Department of Pharmacology and Toxicology, University of Utah, College of Pharmacy, Salt Lake City 84112, USA., Brown SD, Woodhead JH, Skeen GA, Wolf HH

المصدر: Epilepsia [Epilepsia] 2000; Vol. 41 (S1), pp. 17-20.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print Cited Medium: Print ISSN: 0013-9580 (Print) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*pharmacology , Fructose/*analogs & derivatives , GABA Antagonists/*pharmacology , Neurons/*drug effects , Receptors, GABA/*drug effects , gamma-Aminobutyric Acid/*drug effects, Action Potentials/drug effects ; Animals ; Cells, Cultured ; Cerebral Cortex/cytology ; Cerebral Cortex/drug effects ; Clonazepam/pharmacology ; Evoked Potentials/drug effects ; Flumazenil/pharmacology ; Fructose/pharmacology ; GABA Modulators/pharmacology ; Mice ; Neurons/physiology ; Patch-Clamp Techniques ; Pentylenetetrazole/pharmacology ; Receptors, GABA/physiology ; Seizures/chemically induced ; Seizures/prevention & control ; Topiramate ; gamma-Aminobutyric Acid/pharmacology

المؤلفون: White HS; Department of Pharmacology and Toxicology, University of Utah, College of Pharmacy, Salt Lake City 84112, USA. swhite@msscc.med.utah.edu, Brown SD, Woodhead JH, Skeen GA, Wolf HH

المصدر: Epilepsy research [Epilepsy Res] 1997 Oct; Vol. 28 (3), pp. 167-79.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print Cited Medium: Print ISSN: 0920-1211 (Print) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*therapeutic use , Brain/*drug effects , Chloride Channels/*drug effects , Fructose/*analogs & derivatives , Neurons/*drug effects , gamma-Aminobutyric Acid/*pharmacology, Animals ; Brain/cytology ; Brain/metabolism ; Cells, Cultured ; Convulsants ; Drug Synergism ; Fluorescent Dyes ; Fructose/therapeutic use ; Infusions, Intravenous ; Mice ; Neurons/metabolism ; Patch-Clamp Techniques ; Pentylenetetrazole ; Seizures/chemically induced ; Topiramate