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المؤلفون: Philippe Rigoard, Maarten Moens, Lisa Goudman, Tom Le Tutour, Michel Rochette, Jonathan Dany, Mohamed Et Talby, Manuel Roulaud, Rémi Hervochon, Amine Ounajim, Kévin Nivole, Romain David, Maxime Billot
المساهمون: Pain in Motion, Supporting clinical sciences, STIMULUS research group, Neuroprotection & Neuromodulation, Radiology, Neurosurgery
المصدر: Journal of Clinical Medicine
Volume 12
Issue 5
Pages: 1747مصطلحات موضوعية: surgery, medicine_pharmacology_other, anatomy, neuro-fiber mapping, computerized electrical modeling, neuroanatomy, super-selective spinal cord stimulation, Neuroscience(all), General Medicine, multicolumn spinal cord stimulation (SCS), dorsal columns, somatotopy, conus medullaris
الوصف: Spinal Cord (SC) Anatomy is often assimilated to a morphologically encapsulated neural entity, but its functional anatomy remains only partially understood. We hypothesized that it could be possible to reexplore SC neural networks by performing live electrostimulation mapping, based on “super-selective” Spinal Cord Stimulation (SCS), originally designed as a therapeutical tool to address chronic refractory pain. As a starting point, we initiated a systematic SCS lead programming approach using live electrostimulation mapping on a chronic refractory perineal pain patient, previously implanted with multicolumn SCS at the level of the conus medullaris (T12-L1). It appeared possible to (re)explore the classical anatomy of the conus medullaris using statistical correlations of paresthesia coverage mappings, resulting from 165 different electrical configurations tested. We highlighted that sacral dermatomes were not only located more medially but also deeper than lumbar dermatomes at the level of the conus medullaris, in contrast with classical anatomical descriptions of SC somatotopical organization. As we were finally able to find a morpho-functional description of ‘Philippe-Gombault’s triangle’, in 19th century historical textbooks of neuroanatomy, matching remarkably with these conclusions, the concept of “Neuro-Fiber-Mapping” was introduced.
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8ccdc9ad2162abd359f3f188029a64
https://doi.org/10.20944/preprints202210.0250.v1