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1
المؤلفون: Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E. Kurtz, Cristina E. Tognon, Kara Johnson, Melissa Abel, Anupriya Agarwal, Sammantha Avaylon, Erik Benton, Aurora Blucher, Uma Borate, Theodore P. Braun, Jordana Brown, Jade Bryant, Russell Burke, Amy Carlos, Bill H. Chang, Hyun Jun Cho, Stephen Christy, Cody Coblentz, Aaron M. Cohen, Amanda d’Almeida, Rachel Cook, Alexey Danilov, Kim-Hien T. Dao, Michie Degnin, James Dibb, Christopher A. Eide, Isabel English, Stuart Hagler, Heath Harrelson, Rachel Henson, Hibery Ho, Sunil K. Joshi, Brian Junio, Andy Kaempf, Yoko Kosaka, Ted Laderas, Matt Lawhead, Hyunjung Lee, Jessica T. Leonard, Chenwei Lin, Evan F. Lind, Selina Qiuying Liu, Pierrette Lo, Marc M. Loriaux, Samuel Luty, Julia E. Maxson, Tara Macey, Jacqueline Martinez, Jessica Minnier, Andrea Monteblanco, Motomi Mori, Quinlan Morrow, Dylan Nelson, Justin Ramsdill, Angela Rofelty, Alexandra Rogers, Kyle A. Romine, Peter Ryabinin, Jennifer N. Saultz, David A. Sampson, Samantha L. Savage, Robert Schuff, Robert Searles, Rebecca L. Smith, Stephen E. Spurgeon, Tyler Sweeney, Ronan T. Swords, Aashis Thapa, Karina Thiel-Klare, Elie Traer, Jake Wagner, Beth Wilmot, Joelle Wolf, Guanming Wu, Amy Yates, Haijiao Zhang, Christopher R. Cogle, Robert H. Collins, Michael W. Deininger, Christopher S. Hourigan, Craig T. Jordan, Tara L. Lin, Micaela E. Martinez, Rachel R. Pallapati, Daniel A. Pollyea, Anthony D. Pomicter, Justin M. Watts, Scott J. Weir, Brian J. Druker, Shannon K. McWeeney, Jeffrey W. Tyner
المصدر: Cancer Cell. 40:850-864.e9
مصطلحات موضوعية: Cohort Studies, Leukemia, Myeloid, Acute, Cancer Research, Oncology, Humans, Cell Differentiation, Receptors, Cell Surface, Transcriptome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6098b4d093afd3e38ecac02c438f88
https://doi.org/10.1016/j.ccell.2022.07.002 -
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المؤلفون: Patrice Lee, Hibery Ho, David K. Edwards, Selina Qiuying Liu, Angela Rofelty, David Sweeney, Shannon K. McWeeney, Alexey V. Danilov, David Chantry, Stephen E. Spurgeon, Jeffrey W. Tyner, Brian J. Druker, Christopher A. Eide, Marc M. Loriaux, Anupriya Agarwal
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Chronic lymphocytic leukemia, Colony stimulating factor 1 receptor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, colony-stimulating factor 1 receptor, medicine, tumor microenvironment, Tumor microenvironment, Hematology, tumor-associated macrophages, business.industry, Monocyte, medicine.disease, 3. Good health, small-molecule inhibitors, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, Ibrutinib, Cancer research, chronic lymphocytic leukemia, Idelalisib, business, Priority Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86a0bbd548169c03c3a3266c4841fdd
https://doi.org/10.18632/oncotarget.25191 -
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المؤلفون: Jason D. MacManiman, Jason Gotlib, Emily A. Stevens, Peter L. Greenberg, Melissa L. Abel, Samuel B. Luty, Marc M. Loriaux, Jason C. Paik, Swaleh Bahamadi, Jeffrey W. Tyner, Julia E. Maxson, Christopher A. Eide, Samantha L. Savage
المصدر: Clinical Cancer Research. 22:757-764
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Glycosylation, DNA Mutational Analysis, Chronic neutrophilic leukemia, Mutant, Biology, Ligands, medicine.disease_cause, Article, Cell Line, Mice, 03 medical and health sciences, Bone Marrow, Receptors, Colony-Stimulating Factor, medicine, Animals, Humans, Codon, Protein Kinase Inhibitors, Bone Marrow Transplantation, Janus Kinases, Mutation, Leukemia, Point mutation, Middle Aged, medicine.disease, Molecular biology, Disease Models, Animal, Cell Transformation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Amino Acid Substitution, Oncology, Atypical chronic myeloid leukemia, Female, Bone marrow, Janus kinase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f2116441cfd4006dc1506ba5d3860
https://doi.org/10.1158/1078-0432.ccr-14-3100 -
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المؤلفون: Phillip A. Wilmarth, Jianya Huan, Natalya A. Goloviznina, Noah I. Hornick, A N Kamimae Lanning, Larry L. David, Bill H. Chang, Peter Kurre, T Mori, Charles T. Roberts, John R. Chevillet, Anupama Narla, Marc M. Loriaux
المصدر: Leukemia. 29:2285-2295
مصطلحات موضوعية: Cancer Research, Stromal cell, HL-60 Cells, Biology, Exosomes, Exosome, Article, Mice, Paracrine signalling, Bone Marrow, Cell Movement, medicine, Animals, Humans, Progenitor cell, Hematology, Hematopoietic Stem Cells, medicine.disease, Hematopoiesis, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Haematopoiesis, Leukemia, medicine.anatomical_structure, Oncology, Immunology, Cancer research, Bone marrow, Stem cell
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المؤلفون: Stephen E. Spurgeon, Monika A. Davare, Marc M. Loriaux, Selina Qiuying Liu, Matthew B. Siegel, Brian J. Druker, Jeffrey W. Tyner, Emma C. Scott
المصدر: Oncotarget
مصطلحات موضوعية: Melphalan, Apoptosis, Drug resistance, Pharmacology, Small Molecule Libraries, resistance, 03 medical and health sciences, 0302 clinical medicine, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, Acetamides, Antineoplastic Combined Chemotherapy Protocols, bromodomain, medicine, Humans, Neoplasm, cardiovascular diseases, neoplasms, Multiple myeloma, Cell Proliferation, 030304 developmental biology, 0303 health sciences, business.industry, Cell growth, Bortezomib, bortezomib, Drug Synergism, Azepines, BET, medicine.disease, 3. Good health, Bromodomain, myeloma, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Proteasome inhibitor, Cancer research, Multiple Myeloma, business, Research Paper, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba8a9b9a89037a734bd722c662ec491
https://doi.org/10.18632/oncotarget.4214 -
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المؤلفون: Brian J. Druker, Kevin S. Currie, Patricia Maciejewski, Russell T. Burke, Brian J. Lannutti, Julie DiPaolo, Stephen E. Spurgeon, Marc M. Loriaux, Sarah A. Meadows, Scott A. Mitchell, Astrid S. Clarke
المصدر: Oncotarget
مصطلحات موضوعية: Indazoles, Chronic lymphocytic leukemia, B-cell receptor, Syk, Apoptosis, Biology, Fostamatinib, spleen tyrosine kinase, hemic and lymphatic diseases, PI3 kinase, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Syk Kinase, Chronic Lymphocytic Leukemia, Phosphorylation, Protein Kinase Inhibitors, Quinazolinones, breakpoint cluster region, Intracellular Signaling Peptides and Proteins, Drug Synergism, BCR Signaling Pathway, Protein-Tyrosine Kinases, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, signaling pathways, Leukemia, Oncology, Purines, Pyrazines, Cancer research, Idelalisib, medicine.drug, Research Paper, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586b96018817e74b23f80ce982b02789
http://europepmc.org/articles/PMC4011593 -
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المؤلفون: Elie Traer, Paul Tardi, Tibor Kovacsovics, Stephen E. Spurgeon, Marc M. Loriaux, Max J. Gordon, Lawrence D. Mayer, Jeffrey W. Tyner
المصدر: Leukemia research. 53
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antimetabolites, Antineoplastic, Daunorubicin, Chronic lymphocytic leukemia, Pharmacology, Biology, 03 medical and health sciences, Inhibitory Concentration 50, 0302 clinical medicine, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Tumor Cells, Cultured, Cytotoxic T cell, Humans, Antibiotics, Antineoplastic, Cytarabine, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Lymphoma, Leukemia, 030104 developmental biology, Oncology, fms-Like Tyrosine Kinase 3, 030220 oncology & carcinogenesis, Fms-Like Tyrosine Kinase 3, Liposomes, Mutation, Blast Crisis, Ex vivo, medicine.drug
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المؤلفون: Bernard Séguin, Guangheng Li, Nicolle E. Hofmann, Atiya Mansoor, Shay Bracha, Charles Keller, Elaine T. Huang, Lara E. Davis, Marc M. Loriaux, Jinu Abraham, John E. Mata, Stuart C. Helfand, Kevin Marley, Jeffrey W. Tyner
المصدر: Pediatric Blood & Cancer. 60:1313-1319
مصطلحات موضوعية: Drug, Oncology, medicine.medical_specialty, business.industry, medicine.drug_class, media_common.quotation_subject, Hematology, medicine.disease, Response to treatment, Tyrosine-kinase inhibitor, Surgery, Metastasis, Clinical trial, Dasatinib, Internal medicine, Pediatrics, Perinatology and Child Health, Medicine, Osteosarcoma, Personalized therapy, business, media_common, medicine.drug
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المؤلفون: Markus Müschen, Jeffrey W. Tyner, Marc M. Loriaux, Vincent T Bicocca, Brian J. Druker, Behzad Kharabi Masouleh, Bill H. Chang
المصدر: Cancer Cell. 22(5):656-667
مصطلحات موضوعية: Cancer Research, B-cell receptor, Dasatinib, Biology, Receptor Tyrosine Kinase-like Orphan Receptors, Translocation, Genetic, Article, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell surface receptor, hemic and lymphatic diseases, medicine, Gene silencing, Humans, Gene Silencing, Phosphorylation, Receptor, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, Kinase, Cell Biology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Gene Expression Regulation, Neoplastic, Thiazoles, Pyrimidines, Oncology, Chromosomes, Human, Pair 1, 030220 oncology & carcinogenesis, Pre-B Cell Receptors, ROR1, Cancer research, Chromosomes, Human, Pair 19, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction
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المصدر: Pediatric Blood & Cancer
مصطلحات موضوعية: Male, Oncology, medicine.medical_specialty, Combination therapy, Dasatinib, Antineoplastic Agents, Chromosomal translocation, In Vitro Techniques, Pre-B Acute Lymphoblastic Leukemia, Translocation, Genetic, 03 medical and health sciences, 0302 clinical medicine, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, hemic and lymphatic diseases, Internal medicine, Humans, Medicine, Lymphocytes, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, business.industry, Lymphoblast, Hematology, Gene rearrangement, In vitro, 3. Good health, Thiazoles, Pyrimidines, 030220 oncology & carcinogenesis, Pediatrics, Perinatology and Child Health, Immunology, Brief Reports, E2A-HLF, Stem cell, ALL, business, Chromosomes, Human, Pair 19, Chromosomes, Human, Pair 17, medicine.drug