المؤلفون: Guenthoer P; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Fuchs K; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Reischl G; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Quintanilla-Martinez L; Department of Pathology, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Gonzalez-Menendez I; Department of Pathology, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Laufer S; Department of Pharmaceutical and Medicinal Chemistry, University of Tuebingen, Tuebingen, Germany., Pichler BJ; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University of Tuebingen, Tuebingen, Germany., Kneilling M; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University of Tuebingen, Tuebingen, Germany. manfred.kneilling@med.uni-tuebingen.de.; Department of Dermatology, Eberhard Karls University of Tuebingen, Tuebingen, Germany. manfred.kneilling@med.uni-tuebingen.de.

المصدر: Inflammopharmacology [Inflammopharmacology] 2019 Dec; Vol. 27 (6), pp. 1217-1227. Date of Electronic Publication: 2019 Apr 29.

نوع المنشور: Evaluation Study; Journal Article

بيانات الدورية: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Experimental/*drug therapy , Dibenzocycloheptenes/*therapeutic use , Imidazoles/*therapeutic use , Mitogen-Activated Protein Kinase 10/*antagonists & inhibitors , Protein Kinase Inhibitors/*therapeutic use , Pyridines/*therapeutic use , p38 Mitogen-Activated Protein Kinases/*antagonists & inhibitors, Animals ; Arthritis, Experimental/diagnostic imaging ; Dibenzocycloheptenes/pharmacology ; Disease Models, Animal ; Glucose-6-Phosphate Isomerase/immunology ; Imidazoles/pharmacology ; Mice ; Mice, Inbred BALB C ; Misonidazole/analogs & derivatives ; Misonidazole/pharmacokinetics ; Positron-Emission Tomography ; Pyridines/pharmacology

المؤلفون: Wang H; Toxicology Program in the Department of Environmental and Occupational Health Science, University of Washington, United States., Engstrom AK; Toxicology Program in the Department of Environmental and Occupational Health Science, University of Washington, United States., Xia Z; Toxicology Program in the Department of Environmental and Occupational Health Science, University of Washington, United States. Electronic address: zxia@uw.edu.

المصدر: Toxicology [Toxicology] 2017 Apr 01; Vol. 380, pp. 30-37. Date of Electronic Publication: 2017 Feb 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185 (Electronic) Linking ISSN: 0300483X NLM ISO Abbreviation: Toxicology Subsets: MEDLINE

مواضيع طبية MeSH: Cadmium/*toxicity , Cell Proliferation/*drug effects , Mitogen-Activated Protein Kinase 10/*metabolism , Neural Stem Cells/*drug effects , p38 Mitogen-Activated Protein Kinases/*metabolism, Animals ; Apoptosis/drug effects ; Cells, Cultured ; Lateral Ventricles/cytology ; Lateral Ventricles/drug effects ; Lateral Ventricles/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mitogen-Activated Protein Kinase 10/genetics ; Neural Stem Cells/pathology ; Phosphorylation ; p38 Mitogen-Activated Protein Kinases/genetics

المؤلفون: de Lemos L; Unitat de Farmacologia i Farmacognòsia Facultat de Farmàcia, Institut de Biomedicina (IBUB), Centros de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat de Barcelona, Barcelona, Spain., Junyent F, Verdaguer E, Folch J, Romero R, Pallàs M, Ferrer I, Auladell C, Camins A

المصدر: Journal of neurochemistry [J Neurochem] 2010 Sep 01; Vol. 114 (5), pp. 1315-22. Date of Electronic Publication: 2010 Jun 08.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

مواضيع طبية MeSH: Kainic Acid/*pharmacology , Mitogen-Activated Protein Kinase 1/*metabolism , Mitogen-Activated Protein Kinase 10/*metabolism , Mitogen-Activated Protein Kinase 3/*metabolism , Mitogen-Activated Protein Kinase 6/*metabolism , p38 Mitogen-Activated Protein Kinases/*metabolism, Animals ; Enzyme Activation/drug effects ; Enzyme Activation/genetics ; Excitatory Amino Acid Agonists/pharmacology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitogen-Activated Protein Kinase 10/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 10/deficiency ; Mitogen-Activated Protein Kinase 10/genetics ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors ; Phosphorylation/drug effects ; Phosphorylation/genetics ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors

المؤلفون: Peifer C; Institute of Pharmacy, Department of Pharmaceutical and Medicinal Chemistry, Eberhard-Karls-University Tübingen, Auf der Morgenstelle 8/B, D-72076 Tübingen, Germany. christian.peifer@uni-tuebingen.de, Kinkel K, Abadleh M, Schollmeyer D, Laufer S

المصدر: Journal of medicinal chemistry [J Med Chem] 2007 Mar 22; Vol. 50 (6), pp. 1213-21. Date of Electronic Publication: 2007 Feb 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Heterocyclic Compounds, 4 or More Rings/*chemical synthesis , Quinolones/*chemical synthesis , p38 Mitogen-Activated Protein Kinases/*antagonists & inhibitors, Binding Sites ; Crystallography, X-Ray ; Heterocyclic Compounds, 4 or More Rings/chemistry ; Mitogen-Activated Protein Kinase 10/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 10/chemistry ; Models, Molecular ; Quinolones/chemistry ; Structure-Activity Relationship ; p38 Mitogen-Activated Protein Kinases/chemistry

المؤلفون: Kamenecka T; Department of Molecular Therapeutics and Translational Research Institute, The Scripps Research Institute, Jupiter, FL 33458, USA., Habel J, Duckett D, Chen W, Ling YY, Frackowiak B, Jiang R, Shin Y, Song X, LoGrasso P

المصدر: The Journal of biological chemistry [J Biol Chem] 2009 May 08; Vol. 284 (19), pp. 12853-61. Date of Electronic Publication: 2009 Mar 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*pharmacology , Mitogen-Activated Protein Kinase 10/*antagonists & inhibitors , Pyrazoles/*chemistry , Pyrazoles/*pharmacology , p38 Mitogen-Activated Protein Kinases/*antagonists & inhibitors, Activating Transcription Factor 2/metabolism ; Animals ; Cells, Cultured ; Crystallography, X-Ray ; Humans ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Models, Molecular ; Phosphorylation/drug effects ; Protein Conformation ; Rats ; Structure-Activity Relationship

المؤلفون: Fricker M; Department of Molecular and Cellular Neuroscience, Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Harlow, Essex, England, UK., Lograsso P, Ellis S, Wilkie N, Hunt P, Pollack SJ

المصدر: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2005 Jun 15; Vol. 438 (2), pp. 195-205.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print Cited Medium: Print ISSN: 0003-9861 (Print) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphate/*chemistry , Mitogen-Activated Protein Kinase 10/*chemistry , p38 Mitogen-Activated Protein Kinases/*metabolism, Alanine/chemistry ; Amino Acids/chemistry ; Animals ; Anthracenes/pharmacology ; Binding Sites ; Biotinylation ; Crystallography, X-Ray ; Enzyme Inhibitors/pharmacology ; Fluorescence Resonance Energy Transfer ; Glutathione/metabolism ; Humans ; Imidazoles/pharmacology ; Inhibitory Concentration 50 ; Isoleucine/chemistry ; Kinetics ; MAP Kinase Signaling System ; Models, Biological ; Models, Chemical ; Models, Molecular ; Mutation ; Phosphorylation ; Point Mutation ; Protein Binding ; Protein Folding ; Pyrimidines/pharmacology ; Valine/chemistry

المؤلفون: Pin-Hong Li, Li-Qun Wang, Jia-Yang He, Xiang-Long Zhu, Wei Huang, Shao-Wen Wang, Qi-Wei Qin, Hong-Yan Sun

المصدر: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

مصطلحات موضوعية: food.ingredient, Iridovirus, medicine.medical_treatment, Immunology, Epinephelus coioides, Apoptosis, Biology, Virus Replication, p38 Mitogen-Activated Protein Kinases, Virus, immune response, Proinflammatory cytokine, Fish Diseases, food, Immune system, Mitogen-Activated Protein Kinase 10, microRNA, medicine, Animals, Immunology and Allergy, Original Research, Innate immune system, Immunotherapy, RC581-607, miR-124, DNA Virus Infections, Immunity, Innate, Cell biology, MicroRNAs, SGIV, Viral replication, viral replication, Bass, Immunologic diseases. Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570d06982f0e80be8c443f446f446d0d
https://www.frontiersin.org/articles/10.3389/fimmu.2021.767813/full

المؤلفون: Kerstin Fuchs, Irene Gonzalez-Menendez, Manfred Kneilling, Philipp Guenthoer, Bernd J. Pichler, Leticia Quintanilla-Martinez, Gerald Reischl, Stefan Laufer

المصدر: Inflammopharmacology. 27:1217-1227

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Pyridines, p38 mitogen-activated protein kinases, Immunology, Arthritis, Dibenzocycloheptenes, Pharmacology, p38 Mitogen-Activated Protein Kinases, Mice, 03 medical and health sciences, 0302 clinical medicine, Mitogen-Activated Protein Kinase 10, In vivo, medicine, Animals, Pharmacology (medical), Misonidazole, Protein Kinase Inhibitors, Mice, Inbred BALB C, biology, Chemistry, Glucose-6-Phosphate Isomerase, Imidazoles, Autoantibody, medicine.disease, Arthritis, Experimental, Disease Models, Animal, 030104 developmental biology, Positron-Emission Tomography, Rheumatoid arthritis, Mitogen-activated protein kinase, biology.protein, FMISO, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0565b2359f511068869f54f1b4f9e3
https://doi.org/10.1007/s10787-019-00593-6

المؤلفون: Anna K. Engstrom, Hao Wang, Zhengui Xia

المصدر: Toxicology. 380:30-37

مصطلحات موضوعية: Male, 0301 basic medicine, p38 mitogen-activated protein kinases, Subventricular zone, Apoptosis, Mice, Transgenic, Biology, Toxicology, p38 Mitogen-Activated Protein Kinases, Article, Mice, 03 medical and health sciences, Neural Stem Cells, Mitogen-Activated Protein Kinase 10, Lateral Ventricles, medicine, Animals, Phosphorylation, Progenitor cell, Cells, Cultured, Cell Proliferation, Kinase, Neurogenesis, Neurotoxicity, medicine.disease, Neural stem cell, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, nervous system, Mitogen-activated protein kinase, Immunology, biology.protein, Cadmium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bdce80bbcda38c60b135ef9045ee1f
https://doi.org/10.1016/j.tox.2017.01.013

المؤلفون: Shiler Khaledi, Shamseddin Ahmadi

المصدر: Metabolic brain disease. 35(4)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, medicine.medical_specialty, p38 mitogen-activated protein kinases, Anxiety, Biochemistry, Hippocampus, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Mitogen-Activated Protein Kinase 10, Internal medicine, Gene expression, medicine, Hippocampus (mythology), Animals, Phosphorylation, Rats, Wistar, Hepatic encephalopathy, Ligation, biology, Chemistry, medicine.disease, Rats, Blot, Disease Models, Animal, 030104 developmental biology, Endocrinology, Liver, Mitogen-activated protein kinase, Hepatic Encephalopathy, biology.protein, Neurology (clinical), Bile Ducts, medicine.symptom, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105e44d6e654a6871e0de255d4b0008c
https://pubmed.ncbi.nlm.nih.gov/32052257