يعرض 1 - 2 نتائج من 2 نتيجة بحث عن '"Halleux C"', وقت الاستعلام: 1.59s تنقيح النتائج
  1. 1
    دورية أكاديمية
    1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: a novel series of potent calcium-sensing receptor antagonists.

    المؤلفون: Widler L; Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland. leo.widler@novartis.com, Altmann E, Beerli R, Breitenstein W, Bouhelal R, Buhl T, Gamse R, Gerspacher M, Halleux C, John MR, Lehmann H, Kalb O, Kneissel M, Missbach M, Müller IR, Reidemeister S, Renaud J, Taillardat A, Tommasi R, Weiler S, Wolf RM, Seuwen K

    المصدر: Journal of medicinal chemistry [J Med Chem] 2010 Mar 11; Vol. 53 (5), pp. 2250-63.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

    مواضيع طبية MeSH: Bone Density Conservation Agents/*chemical synthesis , Parathyroid Hormone/*metabolism , Quinazolinones/*chemical synthesis , Receptors, Calcium-Sensing/*metabolism, Administration, Oral ; Animals ; Bone Density Conservation Agents/administration & dosage ; Bone Density Conservation Agents/chemistry ; Bone Density Conservation Agents/pharmacokinetics ; Dogs ; Inhibitory Concentration 50 ; Male ; Quinazolinones/administration & dosage ; Quinazolinones/chemistry ; Quinazolinones/pharmacokinetics ; Rats ; Rats, Wistar ; Receptors, Calcium-Sensing/antagonists & inhibitors ; Receptors, Calcium-Sensing/genetics ; Structure-Activity Relationship

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  2. 2
    دورية أكاديمية
    Signaling in human osteoblasts by extracellular nucleotides. Their weak induction of the c-fos proto-oncogene via Ca2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase.

    المؤلفون: Bowler WB; Human Bone Cell Research Group, University of Liverpool, Liverpool L69 3GE, United Kingdom. wbb@liv.ac.uk, Dixon CJ, Halleux C, Maier R, Bilbe G, Fraser WD, Gallagher JA, Hipskind RA

    المصدر: The Journal of biological chemistry [J Biol Chem] 1999 May 14; Vol. 274 (20), pp. 14315-24.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

    مواضيع طبية MeSH: Signal Transduction*, Calcium/*metabolism , Calcium-Calmodulin-Dependent Protein Kinases/*metabolism , Cyclic AMP-Dependent Protein Kinases/*metabolism , Osteoblasts/*physiology , Parathyroid Hormone/*metabolism , Proto-Oncogene Proteins c-fos/*metabolism, Adenosine Triphosphate/metabolism ; Cells, Cultured ; Humans ; Osteoblasts/enzymology ; Proto-Oncogene Mas ; Receptors, Purinergic P2/biosynthesis ; Receptors, Purinergic P2Y1 ; Receptors, Purinergic P2Y2 ; Uridine Triphosphate/metabolism

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