المؤلفون: Crouch, Elizabeth E, Bhaduri, Aparna, Andrews, Madeline G, Cebrian-Silla, Arantxa, Diafos, Loukas N, Birrueta, Janeth Ochoa, Wedderburn-Pugh, Kaylee, Valenzuela, Edward J, Bennett, Neal K, Eze, Ugomma C, Sandoval-Espinosa, Carmen, Chen, Jiapei, Mora, Cristina, Ross, Jayden M, Howard, Clare E, Gonzalez-Granero, Susana, Lozano, Jaime Ferrer, Vento, Maximo, Haeussler, Maximilian, Paredes, Mercedes F, Nakamura, Ken, Garcia-Verdugo, Jose Manuel, Alvarez-Buylla, Arturo, Kriegstein, Arnold R, Huang, Eric J

المصدر: Cell. 185(20)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Pediatric, Neurosciences, Stem Cell Research - Embryonic - Human, Stem Cell Research, Stem Cell Research - Nonembryonic - Non-Human, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Underpinning research, Aetiology, Brain, Collagen, Endothelial Cells, Humans, Laminin, Midkine, Neovascularization, Pathologic, Neovascularization, Physiologic, Pericytes, angiogenesis, arterial endothelial cells, blood brain barrier, cortical organoids, endothelial cells, human prenatal brain development, mural cells, pericytes, smooth muscle cells, tip cells, venous and capillary endothelial cells, ventricular zone, Human prenatal brain development, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4333g2f6

المؤلفون: Avansini, Simoni H, Puppo, Francesca, Adams, Jason W, Vieira, Andre S, Coan, Ana C, Rogerio, Fabio, Torres, Fabio R, Araújo, Patricia AOR, Martin, Mariana, Montenegro, Maria A, Yasuda, Clarissa L, Tedeschi, Helder, Ghizoni, Enrico, França, Andréa FEC, Alvim, Marina KM, Athié, Maria C, Rocha, Cristiane S, Almeida, Vanessa S, Dias, Elayne V, Delay, Lauriane, Molina, Elsa, Yaksh, Tony L, Cendes, Fernando, Lopes Cendes, Iscia, Muotri, Alysson R

المصدر: Brain. 145(6)

مصطلحات موضوعية: Congenital Structural Anomalies, Pediatric, Neurosciences, Aetiology, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Underpinning research, Neurological, Brain, Epilepsy, Humans, Infant, Newborn, Malformations of Cortical Development, Malformations of Cortical Development, Group I, Neurons, focal cortical dysplasia, cortical organoids, cell adhesion, cell proliferation, neuronal network, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5fw10955

المؤلفون: Trujillo, Cleber A, Adams, Jason W, Negraes, Priscilla D, Carromeu, Cassiano, Tejwani, Leon, Acab, Allan, Tsuda, Ben, Thomas, Charles A, Sodhi, Neha, Fichter, Katherine M, Romero, Sarah, Zanella, Fabian, Sejnowski, Terrence J, Ulrich, Henning, Muotri, Alysson R

المصدر: EMBO Molecular Medicine. 13(1)

مصطلحات موضوعية: Rare Diseases, Stem Cell Research - Induced Pluripotent Stem Cell, Genetics, Neurodegenerative, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Pediatric, Neurosciences, Intellectual and Developmental Disabilities (IDD), Rett Syndrome, Stem Cell Research - Nonembryonic - Human, Stem Cell Research, Stem Cell Research - Embryonic - Human, Development of treatments and therapeutic interventions, Aetiology, 2.1 Biological and endogenous factors, 5.2 Cellular and gene therapies, Neurological, Congenital, Bridged Bicyclo Compounds, Heterocyclic, Female, Gene Knockout Techniques, Humans, Methyl-CpG-Binding Protein 2, Neurons, Organoids, Phenotype, Pyrrolidinones, Quinuclidines, cortical organoids, drug discovery, MECP2 mosaicism, neurodevelopmental disease modeling, stem cells, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6ms5s334

المؤلفون: Fiddes, Ian T, Lodewijk, Gerrald A, Mooring, Meghan, Bosworth, Colleen M, Ewing, Adam D, Mantalas, Gary L, Novak, Adam M, van den Bout, Anouk, Bishara, Alex, Rosenkrantz, Jimi L, Lorig-Roach, Ryan, Field, Andrew R, Haeussler, Maximilian, Russo, Lotte, Bhaduri, Aparna, Nowakowski, Tomasz J, Pollen, Alex A, Dougherty, Max L, Nuttle, Xander, Addor, Marie-Claude, Zwolinski, Simon, Katzman, Sol, Kriegstein, Arnold, Eichler, Evan E, Salama, Sofie R, Jacobs, Frank MJ, Haussler, David

المصدر: Cell. 173(6)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Intellectual and Developmental Disabilities (IDD), Mental Health, Pediatric, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, Congenital Structural Anomalies, Stem Cell Research - Nonembryonic - Human, Rare Diseases, Schizophrenia, Neurosciences, Brain Disorders, 1.1 Normal biological development and functioning, Underpinning research, Neurological, Animals, Brain, Cell Differentiation, Cerebral Cortex, Embryonic Stem Cells, Female, Gene Deletion, Genes, Reporter, Gorilla gorilla, HEK293 Cells, Humans, Neocortex, Neural Stem Cells, Neurogenesis, Neuroglia, Neurons, Pan troglodytes, Receptor, Notch2, Sequence Analysis, RNA, Signal Transduction, 1q21.1, Notch signaling, autism, cortical organoids, human evolution, neural stem cells, neurodevelopment, neurodevelopmental disorders, segmental duplications, structural variation, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4w90w81n

المؤلفون: Simoni H Avansini, Francesca Puppo, Jason W Adams, Andre S Vieira, Ana C Coan, Fabio Rogerio, Fabio R Torres, Patricia A O R Araújo, Mariana Martin, Maria A Montenegro, Clarissa L Yasuda, Helder Tedeschi, Enrico Ghizoni, Andréa F E C França, Marina K M Alvim, Maria C Athié, Cristiane S Rocha, Vanessa S Almeida, Elayne V Dias, Lauriane Delay, Elsa Molina, Tony L Yaksh, Fernando Cendes, Iscia Lopes Cendes, Alysson R Muotri

المصدر: Brain : a journal of neurology, vol 145, iss 6

مصطلحات موضوعية: 1.1 Normal biological development and functioning, Medical and Health Sciences, Underpinning research, Group I, 2.1 Biological and endogenous factors, Humans, Aetiology, Pediatric, Neurons, Neurology & Neurosurgery, Epilepsy, Psychology and Cognitive Sciences, Neurosciences, Infant, Newborn, Infant, Brain, cell adhesion, Newborn, cortical organoids, Malformations of Cortical Development, cell proliferation, Malformations of Cortical Development, Group I, Neurological, Congenital Structural Anomalies, neuronal network, Neurology (clinical), focal cortical dysplasia

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf7f2810695e644eb033fa926d3719a
https://pubmed.ncbi.nlm.nih.gov/34957478

المؤلفون: Maximilian Haeussler, Meghan Mooring, David Haussler, Gary L. Mantalas, Marie-Claude Addor, Max L. Dougherty, Colleen M. Bosworth, Xander Nuttle, Andrew R. Field, Alex Bishara, Alex A. Pollen, Lotte Russo, Arnold R. Kriegstein, Simon Zwolinski, Gerrald A Lodewijk, Adam D. Ewing, Aparna Bhaduri, Jimi L. Rosenkrantz, Ryan Lorig-Roach, Sofie R. Salama, Frank M. J. Jacobs, Anouk van den Bout, Adam M. Novak, Tomasz J. Nowakowski, Evan E. Eichler, Ian T. Fiddes, Sol Katzman

المساهمون: Molecular Neuroscience (SILS, FNWI)

المصدر: Cell, vol 173, iss 6
Cell, 173(6), 1356-1369. Cell Press
Cell

مصطلحات موضوعية: 0301 basic medicine, Microcephaly, Cellular differentiation, Neocortex, Medical and Health Sciences, Neural Stem Cells, Genes, Reporter, Stem Cell Research - Nonembryonic - Human, Gene duplication, Receptor, Notch2, segmental duplications, Notch signaling, Cerebral Cortex, Neurons, Pediatric, neurodevelopment, neurodevelopmental disorders, Neurogenesis, Brain, Cell Differentiation, Biological Sciences, Neural stem cell, Cell biology, 1q21.1, medicine.anatomical_structure, Mental Health, Neurological, Female, Stem Cell Research - Nonembryonic - Non-Human, Neuroglia, Sequence Analysis, Signal Transduction, Receptor, Pan troglodytes, Intellectual and Developmental Disabilities (IDD), 1.1 Normal biological development and functioning, Notch signaling pathway, autism, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, human evolution, Rare Diseases, Underpinning research, medicine, Genetics, Animals, Humans, Reporter, Embryonic Stem Cells, Notch2, Gorilla gorilla, Sequence Analysis, RNA, structural variation, Neurosciences, medicine.disease, Stem Cell Research, Brain Disorders, cortical organoids, 030104 developmental biology, HEK293 Cells, Genes, Schizophrenia, RNA, Congenital Structural Anomalies, Ectopic expression, Gene Deletion, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4212839d713447491e7e090e98d2e962
https://dare.uva.nl/personal/pure/en/publications/humanspecific-notch2nl-genes-affect-notch-signaling-and-cortical-neurogenesis(747a3209-ee89-4d1b-b3c2-fa7b89b4852d).html