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1
المؤلفون: Joi Dunbar, Margaret A. Read, Joseph D. Manna, Alexander Constan, Alfredo C. Castro, Sherri Smith, Gordon Loewen, John Lee, Somarajan J. Nair, Jennifer Hoyt, Martin R. Tremblay, Julian Adams, Jeanne A. Ferguson, Jens Sydor, Veronica Campbell, Matthew Campbell, Karen McGovern, Brendan Arsenault, Marisa O. Peluso, Jylle Nevejans, Vito J. Palombella, Nigel Whitebread, Grogan Michael John, Kerrie Faia, John Soglia, Bennett Carter
المصدر: Xenobiotica. 43:875-885
مصطلحات موضوعية: Male, ATP Binding Cassette Transporter, Subfamily B, Cyclopamine, Health, Toxicology and Mutagenesis, Administration, Oral, Biological Availability, Mice, Inbred Strains, Biology, Pharmacology, Toxicology, Biochemistry, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, hemic and lymphatic diseases, Animals, Humans, Hedgehog Proteins, Tissue Distribution, Enzyme Inhibitors, Volume of distribution, Veratrum Alkaloids, Antagonist, Orosomucoid, General Medicine, Bioavailability, Cytochrome P-450 CYP2C19, Macaca fascicularis, chemistry, Hepatocytes, Microsomes, Liver, Microsome, Female, Aryl Hydrocarbon Hydroxylases, Smoothened, Half-Life
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2
المؤلفون: Alexander A. Constan, Christopher J. Borgert
المصدر: Principles and Practice of Mixtures Toxicology
مصطلحات موضوعية: Drug, business.industry, media_common.quotation_subject, Medicine, Pharmacology, Antagonism, business, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::508df02bd2807440df03e54a5a8a1714
https://doi.org/10.1002/9783527630196.ch13 -
3
المؤلفون: Nicola E. Wilsher, Andrew J. Ratcliffe, Brenda J. Burton, Collis Alan John, Maria G. Belvisi, Iain Mcfarlane Mclay, Chris Maslen, Simon Phipps, Martyn Foster, Kenneth Page, Michael F. Kelley, Bryan Slater, Stephen E Webber, Jayyosi Zaid, Kenneth Pollock, V. Benning, Alex Constan, Elisabeth J. Redford, David J Hele, Jeffrey Mckenna, Glen K. Miller, Véronique Thybaud, Barry Porter, Frank Halley, Marie-Claude Ouldelhkim, Mark A. Birrell, John E. Souness
المصدر: Bioorganic & Medicinal Chemistry. 9:537-554
مصطلحات موضوعية: Lipopolysaccharides, Inflammatory arthritis, medicine.medical_treatment, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Arthritis, Pharmacology, p38 Mitogen-Activated Protein Kinases, Biochemistry, Monocytes, Rats, Sprague-Dawley, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Stability, In vivo, Drug Discovery, Cytochrome P-450 CYP1A1, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, biology, Tumor Necrosis Factor-alpha, Chemistry, Mesylate, Organic Chemistry, Imidazoles, medicine.disease, Rats, Disease Models, Animal, Cytokine, Enzyme inhibitor, Antirheumatic Agents, Enzyme Induction, Rheumatoid arthritis, Immunology, biology.protein, Molecular Medicine, Female, Tumor necrosis factor alpha, Mitogen-Activated Protein Kinases
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4
المؤلفون: Leslie Recio, Byron E. Butterworth, Alexander A. Constan, Linda J. Pluta, Brian A. Wong, Michael V. Templin, Jeffrey I. Everitt, Catherine S. Sprankle
المصدر: Environmental and Molecular Mutagenesis. 31:248-256
مصطلحات موضوعية: Genetically modified mouse, Genetics, Epidemiology, Ratón, DNA damage, Health, Toxicology and Mutagenesis, Mutant, Mutagen, Pharmacology, Biology, medicine.disease_cause, Toxicity, medicine, Mode of action, Genetics (clinical), Carcinogen
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ce096ff2c6c4d15af0c976ad6b3602a8
https://doi.org/10.1002/(sici)1098-2280(1998)31:3<248::aid-em6>3.0.co;2-g -
5
المصدر: Toxicology and Applied Pharmacology. 141:124-132
مصطلحات موضوعية: Pharmacology, chemistry.chemical_compound, Physiologically based pharmacokinetic modelling, Non-competitive inhibition, Pharmacokinetics, Trichloroethylene, Chemistry, Pharmacodynamics, Toxicity, Toxicokinetics, Glutathione, Toxicology
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6Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice
المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 66(2)
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Time Factors, Mice, Inbred Strains, Pharmacology, Toxicology, Models, Biological, chemistry.chemical_compound, Mice, Pharmacokinetics, Administration, Inhalation, medicine, Animals, Carcinogen, Inhalation exposure, Inhalation, Cell Death, Dose-Response Relationship, Drug, Organ Size, medicine.anatomical_structure, chemistry, Liver, Hepatocyte, Toxicity, Carcinogens, Solvents, Female, Chloroform, Bromodeoxyuridine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db8bbf26c19126d7d86c4054a220e1f
https://pubmed.ncbi.nlm.nih.gov/11896286 -
7
المؤلفون: Byron E. Butterworth, Frank L. Gonzalez, Gregory L. Kedderis, Brian A. Wong, Catherine S. Sprankle, Jeffrey I. Everitt, Alexander A. Constan, Jeffrey M. Peters
المصدر: Toxicology and applied pharmacology. 160(2)
مصطلحات موضوعية: Male, medicine.medical_specialty, Necrosis, Mice, Inbred Strains, Biology, Nose, Toxicology, Kidney, Turbinates, chemistry.chemical_compound, Mice, Internal medicine, Administration, Inhalation, medicine, Animals, Carcinogen, Biotransformation, Pharmacology, Mice, Knockout, Cell growth, Cytochrome P450, Cytochrome P-450 CYP2E1, Organ Size, CYP2E1, Immunohistochemistry, Cytochrome P-450 CYP2E1 Inhibitors, medicine.anatomical_structure, Endocrinology, chemistry, Liver, Toxicity, biology.protein, Carcinogens, Chloroform, medicine.symptom, Cell Division, Toxicant
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المؤلفون: J. K. Phillips, Alexander A. Constan, Melvin E. Andersen, Harihara M. Mehendale, Hisham A. El-Masri, Stephen A. Benjamin, Russell S. Thomas, Raymond S. H. Yang, G. R. Sabados
المصدر: Archives of toxicology. 70(11)
مصطلحات موضوعية: Male, Physiologically based pharmacokinetic modelling, Chemistry, Health, Toxicology and Mutagenesis, CCL4, Drug Synergism, General Medicine, Pharmacology, Toxicology, digestive system, Rats, Rats, Sprague-Dawley, chemistry.chemical_compound, Pharmacokinetics, Models, Chemical, Chlordecone, Pharmacodynamics, Toxicity, Carbon tetrachloride, Toxicokinetics, Kepone, Animals, Carbon Tetrachloride
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4ca87b84f9c61865b55f2d056775c4
https://pubmed.ncbi.nlm.nih.gov/8896716 -
9
المصدر: Carcinogenesis. 16(2)
مصطلحات موضوعية: Chromium, Male, Cancer Research, Time Factors, Trichloroethylene, Mitosis, Mutagen, Fresh Water, Pharmacology, medicine.disease_cause, Hazardous Substances, Arsenic, Toxicology, chemistry.chemical_compound, Liver Neoplasms, Experimental, Phenols, Oral administration, medicine, Animals, Carcinogen, chemistry.chemical_classification, biology, Dose-Response Relationship, Drug, Phenol, Chemistry, Benzene, General Medicine, Enzyme assay, Rats, Inbred F344, Rats, medicine.anatomical_structure, Enzyme, Lead, Liver, Hepatocyte, Toxicity, biology.protein, Chloroform, Cell Division, Water Pollutants, Chemical
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984fe85f2e5d34764b19509bdef680f5
https://pubmed.ncbi.nlm.nih.gov/7859362 -
10
المؤلفون: Dennis Constan
المصدر: American Journal of Health-System Pharmacy. 66:2205-2205
مصطلحات موضوعية: Pharmacology, Pharmaceutical care, Health Policy, Library science, Environmental ethics, Sociology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d0bba8eca986591a726f1e4d615a3231
https://doi.org/10.1093/ajhp/66.24.2205a
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