المؤلفون: Wandinger SK; Evotec (München) GmbH, Martinsried, Germany., Lahortiga I; VIB Center for the Biology of Disease, Leuven, Belgium.; KU Leuven, Center for Human Genetics, Leuven, Belgium., Jacobs K; VIB Center for the Biology of Disease, Leuven, Belgium.; KU Leuven, Center for Human Genetics, Leuven, Belgium., Klammer M; Evotec (München) GmbH, Martinsried, Germany., Jordan N; Evotec (München) GmbH, Martinsried, Germany., Elschenbroich S; Evotec (München) GmbH, Martinsried, Germany., Parade M; Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Jacoby E; Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Linders JT; Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Brehmer D; Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Cools J; VIB Center for the Biology of Disease, Leuven, Belgium.; KU Leuven, Center for Human Genetics, Leuven, Belgium., Daub H; Evotec (München) GmbH, Martinsried, Germany.

المصدر: PloS one [PLoS One] 2016 Jan 08; Vol. 11 (1), pp. e0146100. Date of Electronic Publication: 2016 Jan 08 (Print Publication: 2016).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, B-Lymphocytes/*metabolism , Phosphoproteins/*genetics , Proteome/*genetics , Receptor, ErbB-3/*genetics , Receptor, ErbB-4/*genetics, Amino Acid Sequence ; Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/drug effects ; Cell Line ; Gene Expression Regulation ; Gene Regulatory Networks ; Genetic Engineering ; Humans ; Mice ; Molecular Sequence Data ; Neuregulin-1/metabolism ; Neuregulin-1/pharmacology ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Binding ; Protein Interaction Mapping ; Proteome/metabolism ; Receptor, ErbB-3/metabolism ; Receptor, ErbB-4/metabolism

المؤلفون: Klammer M; Dept. of Bioinformatics, Evotec (München) GmbH, Martinsried, Germany., Dybowski JN; Dept. of Bioinformatics, Evotec (München) GmbH, Martinsried, Germany., Hoffmann D; Center for Medical Biotechnology, University of Duisburg-Essen, Essen, Germany., Schaab C; Dept. of Bioinformatics, Evotec (München) GmbH, Martinsried, Germany; Dept. Proteomics and Signal Transduction, Max-Plack Institute for Biochemistry, Martinsried, Germany.

المصدر: PloS one [PLoS One] 2014 Aug 13; Vol. 9 (8), pp. e104504. Date of Electronic Publication: 2014 Aug 13 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Algorithms* , Software*, Neoplasms/*metabolism , Phosphoproteins/*metabolism , Proteomics/*methods , Statistics as Topic/*methods, Computer Simulation ; Humans ; Sample Size

المؤلفون: Schaab C; 1] Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany [2] Max Planck Institute of Biochemistry, Am Klopferspitz 18, Martinsried, Germany., Oppermann FS; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany., Klammer M; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany., Pfeifer H; Department of Medicine, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany., Tebbe A; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany., Oellerich T; 1] Department of Medicine, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany [2] German Cancer Consortium (DKTK), Heidelberg, Germany [3] German Cancer Research Center (DKFZ), Heidelberg, Germany., Krauter J; Department of Medicine, Hematology/Oncology, Medizinische Hochschule Hannover, Hannover, Germany., Levis M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Perl AE; Hematologic Malignancies Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Daub H; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany., Steffen B; Department of Medicine, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany., Godl K; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany., Serve H; 1] Department of Medicine, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany [2] German Cancer Consortium (DKTK), Heidelberg, Germany [3] German Cancer Research Center (DKFZ), Heidelberg, Germany.

المصدر: Leukemia [Leukemia] 2014 Mar; Vol. 28 (3), pp. 716-9. Date of Electronic Publication: 2013 Nov 19.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Proteome*, Antineoplastic Agents/*therapeutic use , Benzothiazoles/*therapeutic use , Biomarkers/*chemistry , Bone Marrow Cells/*chemistry , Leukemia, Myeloid, Acute/*drug therapy , Phenylurea Compounds/*therapeutic use , Phosphoproteins/*chemistry, Humans

المؤلفون: Oppermann FS; Evotec München GmbH, Am Klopferspitz 19a, 82152 Martinsried, Germany., Klammer M, Bobe C, Cox J, Schaab C, Tebbe A, Daub H

المصدر: Journal of proteome research [J Proteome Res] 2013 Sep 06; Vol. 12 (9), pp. 4089-100. Date of Electronic Publication: 2013 Aug 16.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

مواضيع طبية MeSH: Phosphoproteins/*chemistry , Proteome/*chemistry, Crizotinib ; Humans ; Isotope Labeling ; K562 Cells ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Interaction Maps ; Protein Kinase Inhibitors/pharmacology ; Protein Kinases/metabolism ; Protein Processing, Post-Translational/drug effects ; Proteome/metabolism ; Proteomics ; Pyrazoles/pharmacology ; Pyridines/pharmacology ; Tandem Mass Spectrometry

المؤلفون: Weigand S; Discovery Oncology, Pharma Research and Early Development, Roche Diagnostics GmbH, Penzberg, Germany. Stefan.weigand@roche.com, Herting F, Maisel D, Nopora A, Voss E, Schaab C, Klammer M, Tebbe A

المصدر: Cancer research [Cancer Res] 2012 Sep 01; Vol. 72 (17), pp. 4329-39. Date of Electronic Publication: 2012 Jul 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*pharmacology , Antibodies, Monoclonal, Humanized/*pharmacology , Antineoplastic Agents/*pharmacology , Hyaluronan Receptors/*metabolism , Neoplasms/*metabolism , Phosphoproteins/*metabolism , Proteome/*metabolism, Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antineoplastic Agents/administration & dosage ; Computational Biology/methods ; Female ; Humans ; MAP Kinase Signaling System/drug effects ; Mice ; Mice, SCID ; Neoplasms/drug therapy ; Proteomics ; Xenograft Model Antitumor Assays

المؤلفون: Klammer M; Evotec München GmbH, 82152 Martinsried, Germany., Kaminski M, Zedler A, Oppermann F, Blencke S, Marx S, Müller S, Tebbe A, Godl K, Schaab C

المصدر: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2012 Sep; Vol. 11 (9), pp. 651-68. Date of Electronic Publication: 2012 May 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*drug therapy , Carcinoma, Non-Small-Cell Lung/*drug therapy , Lung Neoplasms/*drug therapy , Phosphoproteins/*analysis , Pyrimidines/*pharmacology , Thiazoles/*pharmacology, Biomarkers, Tumor ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Adhesion ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dasatinib ; Drug Resistance, Neoplasm ; Female ; Gene Expression Profiling ; Humans ; Integrin beta4/chemistry ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mass Spectrometry ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Proteome/analysis