نتائج البحث - "Marie-France Hamou"

1

Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)

المساهمون: Neurology, University of Zurich, Wick, Wolfgang

المصدر: Clinical Cancer Research, 22(19), 4797-4806. American Association for Cancer Research Inc.
Clinical Cancer Research, 22(19), 4797-4806
Clinical Cancer Research
Clinical cancer research, vol. 22, no. 19, pp. 4797-4806

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Phases of clinical research, Kaplan-Meier Estimate, 0302 clinical medicine, 1306 Cancer Research, Promoter Regions, Genetic, DNA Modification Methylases, education.field_of_study, Brain Neoplasms, Chemoradiotherapy, Middle Aged, Temsirolimus, 3. Good health, Dacarbazine, 030220 oncology & carcinogenesis, 2730 Oncology, Female, medicine.drug, Adult, medicine.medical_specialty, Population, 610 Medicine & health, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Temozolomide, Humans, education, Aged, Proportional Hazards Models, Brain Neoplasms/drug therapy, Brain Neoplasms/mortality, Brain Neoplasms/radiotherapy, Chemoradiotherapy/methods, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Dacarbazine/administration & dosage, Dacarbazine/analogs & derivatives, Glioblastoma/drug therapy, Glioblastoma/mortality, Glioblastoma/radiotherapy, Promoter Regions, Genetic/genetics, Sirolimus/administration & dosage, Sirolimus/analogs & derivatives, Tumor Suppressor Proteins/genetics, Sirolimus, Performance status, business.industry, Tumor Suppressor Proteins, Surgery, 10040 Clinic for Neurology, 030104 developmental biology, DNA Repair Enzymes, 10032 Clinic for Oncology and Hematology, MGMT-Unmethylated Glioblastoma, business, Glioblastoma

وصف الملف: 1078-0432.CCR-15-3153.full.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d7fef0d1608d3697456d8fd4775b80
https://doi.org/10.1158/1078-0432.ccr-15-3153

2

The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence

المؤلفون: Anastasia Murat, Davide Sciuscio, Burt G. Feuerstein, Annie-Claire Diserens, Mauro Delorenzi, Marie-France Hamou, Eugenia Migliavacca, Anjan Misra, Irene Vassallo, Monika E. Hegi, Eytan Domany, Raphaël Burger, Wanyu L. Lambiv, Tal Shay, Roger Stupp

المصدر: Neuro-Oncology. 13:736-747

مصطلحات موضوعية: Aging, Cancer Research, senescence, Signaling Pathway, Epigenetic Inactivation, Expression, WIF1, Epigenesis, Genetic, Immunoenzyme Techniques, Colorectal-Cancer Cells, Mice, Promoter Methylation, Genes, Tumor Suppressor, tumor suppressor gene, RNA, Small Interfering, Promoter Regions, Genetic, biology, Brain Neoplasms, Reverse Transcriptase Polymerase Chain Reaction, Wnt signaling pathway, LRP5, epigenetic silencing, Candidate Tumor Suppressor Gene, Gene Expression Regulation, Neoplastic, Oncology, Basic and Translational Investigations, Chromosomal region, Female, Beta-catenin, Tumor suppressor gene, Blotting, Western, Wnt pathway, Down-Regulation, Mice, Nude, Cell Line, Tumor, Cell Adhesion, Animals, Humans, Gene silencing, RNA, Messenger, neoplasms, Adaptor Proteins, Signal Transducing, Cell Proliferation, Newly-Diagnosed Glioblastoma, DNA Methylation, Beta-Catenin, Repressor Proteins, Factor-I, biology.protein, Cancer research, Adjuvant Temozolomide, Neurology (clinical), Glioblastoma, Wif1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcf65c552849bbb2fe83f755e434768
https://doi.org/10.1093/neuonc/nor036

3

Validation of Real-Time Methylation-Specific PCR to Determine O6-Methylguanine-DNA Methyltransferase Gene Promoter Methylation in Glioma

المؤلفون: Monika E. Hegi, Eugenia Migliavacca, Ivano Di Stefano, J. Straub, Isabelle Renard, Bruno Flamion, Annie-Claire Diserens, Stephane Califice, Mauro Delorenzi, Katja Bierau, Marie-France Hamou, Fabrice Moreau, Ilse Vlassenbroeck, James DiGuiseppi

المصدر: The Journal of Molecular Diagnostics. 10:332-337

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac132698af8c5cc423e6583151382069
https://doi.org/10.2353/jmoldx.2008.070169

View record from ScienceDirect

Full Text via ClinicalKey

4

MGMT gene silencing and benefit from temozolomide in glioblastoma

المؤلفون: Peter Hau, Thierry Gorlia, Monika E. Hegi, Roger Stupp, René O. Mirimanoff, Johan M. Kros, Johannes A. Hainfellner, Marie-France Hamou, Warren P. Mason, Annie-Claire Diserens, Robert C. Janzer, Nicolas de Tribolet, J. Gregory Cairncross, Jacoline E C Bromberg, Luigi Mariani, Michael Weller

المساهمون: Pathology, Neurology

المصدر: New England Journal of Medicine, vol. 352, no. 10, pp. 997-1003
New England Journal of Medicine, 352(10), 997-1003. Massachussetts Medical Society

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Pathology, Methyltransferase, Polymerase Chain Reaction, Disease-Free Survival, O(6)-Methylguanine-DNA Methyltransferase, Internal medicine, Temozolomide, medicine, Humans, Gene Silencing, Promoter Regions, Genetic, Antineoplastic Agents, Alkylating, neoplasms, Survival analysis, Randomized Controlled Trials as Topic, Carmustine, Brain Neoplasms, business.industry, Hazard ratio, O-6-methylguanine-DNA methyltransferase, General Medicine, DNA Methylation, Survival Analysis, digestive system diseases, Dacarbazine, Chemotherapy, Adjuvant, Antineoplastic Agents, Alkylating/therapeutic use, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, Dacarbazine/analogs & derivatives, Dacarbazine/therapeutic use, Glioblastoma/drug therapy, Glioblastoma/genetics, O(6)-Methylguanine-DNA Methyltransferase/genetics, DNA methylation, Glioblastoma, business, Alkyltransferase, medicine.drug