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المؤلفون: Alex Pavluck, Nicholas Midzi, Brian Chu, Rebecca Willis, Boubacar Kadri, M.L. Kamugisha, Simon Brooker, Djouma Nembot Fabrice, Aba Ange Elvis, Zaid Abdulnafea, Colin MacLeod, Khumbo Kalua, Andeberhan Tesfazion Woldendrias, Upendo Mwingira, Jeremiah Ngondi, Caleb Mpyet, Gretchen A Stevens, Assumpta Lucienne Bella, Garae Mackline, Kamal Hashim Bennawi, Do Seiha, Ana Bakhtiari, Rebecca M. Flueckiger, Wilfried Batcho, Abdallahi Ould Minnih, Georges Yaya, Khamphoua Southisombath, Isaac K. Phiri, Olga Nelson Amiel, Mariamo Abdala, Fatma Juma Omar, Anthony W. Solomon, Francisco Zambroni, Michael Dejene, Jaouad Hammou, Khaled Amer, Genet Kiflu, Portia Manangazira, Tawfik Al-Khatib, Jambi Garap, Marilia Massangaie, Gloria Marina Serrano Chavez, Biruck Kebede, Amza Abdou, Asad Aslam Khan, Paul Courtright, Nicholas Muraguri, Beido Nassirou, Martin Kabore, Djore Dezoumbe, Michael Gichangi, Jialiang Zhao, Drabo Francois, Rachel L. Pullan, Balgesa Elkheir Elshafie, Missamou François, Kaba Keita, Babar Qureshi, Nicholas Olobio, Taka Fira Mduluza, Cece Nieba, Michael Masika, Souleymane Yeo, Siphetthavong Sisaleumsak, Shekhar Sharma, Makoy S. Yibi, Sailesh Mishra, Jean Ndjemba, Lamine Traoré, André Goepogui, George Kabona, Sossinou Awoussi, Nabicassa Meno, Patrick Turyaguma, Boubacar Sarr
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007835 (2019)مصطلحات موضوعية: Male, Bacterial Diseases, Eye Diseases, Stratigraphy, RC955-962, Population Dynamics, Prevalence, Social Sciences, Surveys, Global Health, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Global health, Public and Occupational Health, National Security, Data Management, Aged, 80 and over, Incidence (epidemiology), Geology, Middle Aged, Infectious Diseases, Geography, Trachoma, Research Design, Female, Public aspects of medicine, RA1-1270, Raw data, Risk assessment, Research Article, Neglected Tropical Diseases, Adult, Trichiasis, Computer and Information Sciences, Adolescent, Political Science, Research and Analysis Methods, Young Adult, medicine, Humans, Aged, Survey Research, Population Biology, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Tropical Diseases, medicine.disease, Geographic Distribution, Confidence interval, Ophthalmology, Earth Sciences, Demography
الوصف: Background Trichiasis is present when one or more eyelashes touches the eye. Uncorrected, it can cause blindness. Accurate estimates of numbers affected, and their geographical distribution, help guide resource allocation. Methods We obtained district-level trichiasis prevalence estimates in adults for 44 endemic and previously-endemic countries. We used (1) the most recent data for a district, if more than one estimate was available; (2) age- and sex-standardized corrections of historic estimates, where raw data were available; (3) historic estimates adjusted using a mean adjustment factor for districts where raw data were unavailable; and (4) expert assessment of available data for districts for which no prevalence estimates were available. Findings Internally age- and sex-standardized data represented 1,355 districts and contributed 662 thousand cases (95% confidence interval [CI] 324 thousand–1.1 million) to the global total. Age- and sex-standardized district-level prevalence estimates differed from raw estimates by a mean factor of 0.45 (range 0.03–2.28). Previously non- stratified estimates for 398 districts, adjusted by ×0.45, contributed a further 411 thousand cases (95% CI 283–557 thousand). Eight countries retained previous estimates, contributing 848 thousand cases (95% CI 225 thousand-1.7 million). New expert assessments in 14 countries contributed 862 thousand cases (95% CI 228 thousand–1.7 million). The global trichiasis burden in 2016 was 2.8 million cases (95% CI 1.1–5.2 million). Interpretation The 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.
Author summary As an individual with trichiasis blinks, the eyelashes abrade the cornea, which can lead to corneal opacity and blindness. Through high quality surgery, which involves altering the position of the eyelid margin, it is possible to reduce the number of people with trichiasis. Accurate estimates of the number of persons with trichiasis and their geographical distribution are needed in order to effectively align resources for surgery and other necessary services. We obtained district-level trichiasis prevalence estimates for 44 endemic and previously-endemic countries. We used the most recently available data and expert assessments to estimate the global burden of trichiasis. We estimated that in 2016 the global burden was 2.8 million cases (95% CI 1.1–5.2 million). The 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.وصف الملف: application/pdf
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المؤلفون: Balgesa Elkheir Elshafie, Missamou François, Boubacar Sarr, Boubacar Kadri, Caleb Mpyet, Georges Yaya, Nicholas Olobio, Gretchen A Stevens, Lamine Traoré, Portia Manangazira, Babar Qureshi, Khaled Amer, Kaba Keita, Marilia Massangaie, Colin MacLeod, Rachel L. Pullan, Alex Pavluck, Taka Fira Mduluza, Assumpta Lucienne Bella, Nabicassa Meno, Tawfik Al-Khatib, M.L. Kamugisha, Mariamo Abdala, Ana Bakhtiari, Garae Mackline, Nicholas Midzi, Do Seiha, Jeremiah Ngondi, Jialiang Zhao, Aba Ange Elvis, Olga Nelson Amiel, Nicholas Muraguri, Djore Dezoumbe, Shekhar Sharma, Martin Kabore, Biruck Kebede, Cece Nieba, Michael Masika, Souleymane Yeo, Genet Kiflu, Upendo Mwingira, Siphetthavong Sisaleumsak, Brian Chu, George Kabona, Andeberhan Tesfazion Woldendrias, Asad Aslam Khan, Michael Gichangi, Sossinou Awoussi, Patrick Turyaguma, Drabo Francois, Simon Brooker, Zaid Abdulnafea, André Goepogui, Djouma Nembot Fabrice, Anthony W. Solomon, Khumbo Kalua, Fatma Juma Omar, Wilfried Batcho, Michael Dejene, Paul Courtright, Rebecca Willis, Jaouad Hammou, Rebecca M. Flueckiger, Abdallahi Ould Minnih, Jambi Garap, Gloria Marina Serrano Chavez, Sailesh Mishra, Jean Ndjemba, Beido Nassirou, Isaac K. Phiri, Francisco Zambroni, Amza Abdou, Kamal Hashim Bennawi, Khamphoua Southisombath
مصطلحات موضوعية: Geography, Trachoma, Blindness, Incidence (epidemiology), medicine, Age and sex, Raw data, medicine.disease, Trichiasis, Confidence interval, Demography, District level
الوصف: BackgroundTrichiasis is present when one or more eyelashes touches the eye. Uncorrected, it can cause blindness. Accurate estimates of numbers affected, and their geographical distribution, help guide resource allocation.MethodsWe obtained district-level trichiasis prevalence estimates for 44 endemic and previously-endemic countries. We used (1) the most recent data for a district, if more than one estimate was available; (2) age- and sex-standardized corrections of historic estimates, where raw data were available; (3) historic estimates adjusted using a mean adjustment factor for districts where raw data were unavailable; and (4) expert assessment of available data for districts for which no prevalence estimates were available.FindingsInternally age- and sex-standardized data represented 1,355 districts and contributed 662 thousand cases (95% confidence interval [CI] 324 thousand-1.1 million) to the global total. age- and sex-standardized district-level prevalence estimates differed from raw estimates by a mean factor of 0.45 (range 0.03-2.28). Previously non-standardized estimates for 398 districts, adjusted by ×0.45, contributed a further 411 thousand cases (95% CI 283-557 thousand). Eight countries retained previous estimates, contributing 848 thousand cases (95% CI 225 thousand-1.7 million). New expert assessments in 14 countries contributed 862 thousand cases (95% CI 228 thousand-1.7 million). The global trichiasis burden in 2016 was 2.8 million cases (95% CI 1.1-5.2 million).InterpretationThe 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.Author SummaryAs an individual with trichiasis blinks, the eyelashes abrade the cornea, which can lead to corneal opacity and blindness. Through high quality surgery, which involves correcting the position of the in-turned eyelid, it is possible to reduce the number of people with trichiasis. An accurate estimate of the number of persons with trichiasis and their geographical distribution are needed in order to effectively align resources for surgery and other necessary services. We obtained district-level trichiasis prevalence estimates for 44 endemic and previously-endemic countries. We used the most recently available data and expert assessments to estimate the global burden of trichiasis. We estimated that in 2016 the global burden was 2.8 million cases (95% CI 1.1-5.2 million).The 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b998c111d4d1db56e9979743a59336
https://doi.org/10.1101/348995
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