المؤلفون: Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA. Electronic address: shrager@stanford.edu., Wang Y; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Lee M; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Nesbit S; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Trope W; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Konsker H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Fatodu E; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Berry MS; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Poulstides G; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Norton J; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Burdon T; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Backhus L; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA., Cooke R; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Tang H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affair Palo Alto Health Care System, Palo Alto, CA, USA.

المصدر: Respiratory medicine [Respir Med] 2021 Nov-Dec; Vol. 189, pp. 106620. Date of Electronic Publication: 2021 Sep 21.

نوع المنشور: Clinical Trial Protocol; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: Diaphragm/*drug effects , Diaphragm/*physiopathology , Janus Kinase Inhibitors/*therapeutic use , Piperidines/*therapeutic use , Pyrimidines/*therapeutic use , Respiration, Artificial/*adverse effects, Humans ; Prospective Studies ; Research Design

المؤلفون: Tang H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., L Kennedy C; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; University of Maryland School of Medicine, Baltimore, MD, USA., Lee M; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., Gao Y; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., Xia H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Thoracic-cardio Surgery, First Affiliated Hospital of PLA General Hospital, Beijing, China., Olguin F; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., Fraga DA; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., Ayers K; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA., Choi S; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, Seoul, Korea., Kim M; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA.; VA Palo Alto Healthcare System, Palo Alto, CA, USA., Tehrani A; Respiratory Management Technologies, LLC., San Francisco, CA, USA., Sowb YA; Respiratory Management Technologies, LLC., San Francisco, CA, USA., Rando TA; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Paul F. Glenn Laboratories for the Biology of Aging and Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Palo Alto, CA, USA. Shrager@stanford.edu.; VA Palo Alto Healthcare System, Palo Alto, CA, USA. Shrager@stanford.edu.

المصدر: Scientific reports [Sci Rep] 2017 Nov 06; Vol. 7 (1), pp. 14530. Date of Electronic Publication: 2017 Nov 06.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Oxidative Stress* , Proteolysis* , Respiration, Artificial*/adverse effects, Diaphragm/*metabolism , Smad3 Protein/*metabolism, Animals ; Blotting, Western ; Cells, Cultured ; Diaphragm/physiopathology ; Flow Cytometry ; Isometric Contraction ; Male ; Rats ; Rats, Sprague-Dawley

المؤلفون: Tang H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, United States of America.; Veterans Administration Palo Alto Healthcare System, Palo Alto, California, United States of America., Smith IJ; Rigel Pharmaceuticals, South San Francisco, California, United States of America., Hussain SN; Critical Care Division, Royal Victoria Hospital, Montreal, Quebec, Canada., Goldberg P; Critical Care Division, Royal Victoria Hospital, Montreal, Quebec, Canada., Lee M; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, United States of America.; Veterans Administration Palo Alto Healthcare System, Palo Alto, California, United States of America., Sugiarto S; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, United States of America.; Veterans Administration Palo Alto Healthcare System, Palo Alto, California, United States of America., Godinez GL; Rigel Pharmaceuticals, South San Francisco, California, United States of America., Singh BK; Rigel Pharmaceuticals, South San Francisco, California, United States of America., Payan DG; Rigel Pharmaceuticals, South San Francisco, California, United States of America., Rando TA; Department of Neurology and Neurological Science, Stanford University School of Medicine, Stanford, California, United States of America.; Neurology Service, Veterans Administration Palo Alto Healthcare System, Palo Alto, California, United States of America., Kinsella TM; Rigel Pharmaceuticals, South San Francisco, California, United States of America., Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California, United States of America.; Veterans Administration Palo Alto Healthcare System, Palo Alto, California, United States of America.

المصدر: Molecular medicine (Cambridge, Mass.) [Mol Med] 2015 Feb 19; Vol. 20, pp. 579-89. Date of Electronic Publication: 2015 Feb 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Diaphragm/*metabolism , Janus Kinases/*metabolism , Respiration, Artificial/*adverse effects , STAT Transcription Factors/*metabolism, Adenosine Triphosphate/metabolism ; Adult ; Aged ; Aged, 80 and over ; Animals ; Diaphragm/physiopathology ; Gene Expression Profiling ; HEK293 Cells ; Humans ; Membrane Potential, Mitochondrial ; Middle Aged ; Oxidative Stress ; Rats, Sprague-Dawley ; Signal Transduction

المؤلفون: Tang H; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford School of Medicine, VA Palo Alto Health Care System, 300 Pasteur Drive, Stanford, California 94305-5407, USA., Lee M, Khuong A, Wright E, Shrager JB

المصدر: Muscle & nerve [Muscle Nerve] 2013 Aug; Vol. 48 (2), pp. 272-8. Date of Electronic Publication: 2013 Jun 29.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE

مواضيع طبية MeSH: Diaphragm/*physiopathology , Muscular Atrophy/*etiology , Muscular Atrophy/*pathology , Respiration, Artificial/*adverse effects, Animals ; Apoptosis/physiology ; Blood Gas Analysis ; Body Weight/physiology ; Disease Models, Animal ; Gene Expression Regulation/physiology ; Male ; Mice ; Microtubule Proteins/metabolism ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Myosin Heavy Chains/genetics ; Myosin Heavy Chains/metabolism ; RNA, Messenger/metabolism ; Time Factors ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism