المؤلفون: Toomas Haller, Gert-Jan B. van Ommen, B. H. C. Stricker, Andres Metspalu, Eivind Ness-Jensen, Satu Männistö, Jelle J. Goeman, Kairit Mikkel, Olga Veth, Neeme Tõnisson, Rikje Ruiter, Cornelia M. van Duijn, Casper H.J. van Eijck, Jesse Fest, Kristian Hveem, Markus Perola, Peter A C 't Hoen, Arfan Ikram, Anni Joensuu, Lisanne S. Vijfhuizen

المساهمون: Surgery, Neurology, Epidemiology, Quantitative Genetics, CAMM - Research Program for Clinical and Molecular Metabolism, Research Programs Unit, University of Helsinki, Faculty of Medicine, University Management

المصدر: Endocrinology, 160(7), 1731-1742
Endocrinology, 160, 7, pp. 1731-1742
Endocrinology, 160, 1731-1742
Endocrinology, 160(7), 1731-1742. Endocrine Society
Endocrinology

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, LIVER, Magnetic Resonance Spectroscopy, Glutamine, Logistic regression, Rotterdam Study, Endocrinology, 0302 clinical medicine, EPIDEMIOLOGY, Hormones and Cancer, Stage (cooking), Research Articles, Biological Specimen Banks, 2. Zero hunger, 0303 health sciences, education.field_of_study, Middle Aged, Biobank, 3. Good health, Europe, 030220 oncology & carcinogenesis, Cohort, SURVIVAL, Biomarker (medicine), Female, medicine.medical_specialty, Population, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Pancreatic cancer, medicine, Biomarkers, Tumor, Humans, Metabolomics, Histidine, education, 030304 developmental biology, Aged, business.industry, Case-control study, ROTTERDAM, medicine.disease, Pancreatic Neoplasms, 030104 developmental biology, Early Diagnosis, Case-Control Studies, 3111 Biomedicine, business, Body mass index, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Blood sampling

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c644776ba778768129e83439d0440c4
https://doi.org/10.1210/en.2019-00165

المؤلفون: Krista Fischer, P. Eline Slagboom, Massimo Mangino, Aaron Isaacs, Christian Gieger, Marian Beekman, Joris Deelen, Diana van Heemst, Sarah E. Medland, Nilesh J. Samani, Nicholas G. Martin, Toomas Haller, Veryan Codd, Cornelia M. van Duijn, René Pool, Najaf Amin, Dale R. Nyholt, Ashley van der Spek, Idil Yet, Rui Wang-Sattler, Dorret I. Boomsma, Harmen Draisma, Ayse Demirkan, Linda Broer, Eva Albrecht, Andres Metspalu, Simon P. Mooijaart, Tim D. Spector, H. Eka D. Suchiman, Anjali K. Henders, John Whitfield, Konstantin Strauch, Anika A. M. Vaarhorst, Mait Raag, Harish Dharuri, Margaret J. Wright, Gonneke Willemsen, Eco J. C. de Geus, Grant W. Montgomery

المساهمون: RS: FHML MaCSBio, RS: CARIM - R1 - Thrombosis and haemostasis, Biochemie, RS: Carim - B01 Blood proteins & engineering, Epidemiology, Internal Medicine, APH - Mental Health, APH - Health Behaviors & Chronic Diseases, Biological Psychology, APH - Methodology

المصدر: Scientific Reports
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 9:11623. Nature Publishing Group
Sci. Rep. 9:11623 (2019)
Sci Rep
Scientific Reports, 9(1):11623. Nature Publishing Group
van der Spek, A, Broer, L, Draisma, H H M, Pool, R, Albrecht, E, Beekman, M, Mangino, M, Raag, M, Nyholt, D R, Dharuri, H K, Codd, V, Amin, N, de Geus, E J C, Deelen, J, Demirkan, A, Yet, I, Fischer, K, Haller, T, Henders, A K, Isaacs, A, Medland, S E, Montgomery, G W, Mooijaart, S P, Strauch, K, Suchiman, H E D, Vaarhorst, A A M, van Heemst, D, Wang-Sattler, R, Whitfield, J B, Willemsen, G, Wright, M J, Martin, N G, Samani, N J, Metspalu, A, Eline Slagboom, P, Spector, T D, Boomsma, D I, van Duijn, C M & Gieger, C 2019, ' Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length : the ENGAGE consortium ', Scientific Reports, vol. 9, no. 1, 11623, pp. 11623 . https://doi.org/10.1038/s41598-019-47282-6

مصطلحات موضوعية: Netherlands Twin Register (NTR), Male, 0301 basic medicine, Homocysteine, Metabolite, lcsh:Medicine, 0601 Biochemistry and Cell Biology, medicine.disease_cause, METHIONINE RESTRICTION, Cohort Studies, chemistry.chemical_compound, 0302 clinical medicine, PLASMA TOTAL HOMOCYSTEINE, Leukocytes, lcsh:Science, Telomere Shortening, LIFE-SPAN, Multidisciplinary, Middle Aged, Telomere, 3. Good health, Multidisciplinary Sciences, Telomeres, Lysophosphatidylcholine, CARDIOVASCULAR-DISEASE, Low-density lipoprotein, Science & Technology - Other Topics, Female, Adult, medicine.medical_specialty, 0299 Other Physical Sciences, LOW-DENSITY-LIPOPROTEIN, HEART-DISEASE, Biology, FAMILIAL LONGEVITY, Article, WHITE BLOOD-CELLS, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Diabetes mellitus, Internal medicine, medicine, Metabolomics, Humans, Aged, Science & Technology, Methionine, MORTALITY, lcsh:R, Lipid metabolism, Lipid Metabolism, medicine.disease, ENDOTHELIAL-CELLS, 030104 developmental biology, Endocrinology, chemistry, lcsh:Q, 030217 neurology & neurosurgery, Oxidative stress

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a715e094b57153e3de326d3a9675262a
https://doi.org/10.1038/s41598-019-47282-6

المؤلفون: Amélie Bonnefond, Nancy L. Heard-Costa, Julius S. Ngwa, Jennifer E. Huffman, Tanja B. Grammer, Jaakko Tuomilehto, Lu Qi, Nicholas G. Martin, Massimo Mangino, Henrik Vestergaard, Penny Gordon-Larsen, Reedik Mägi, Natalia V. Rivera, Charles Kooperberg, Alain G. Bertoni, Sarah H. Wild, Robert Luben, Veikko Salomaa, Claude Bouchard, Lynda M. Rose, Patricia A. Peyser, Graciela E. Delgado, Jessica D. Faul, Tuija Tammelin, John C. Chambers, Tsegaselassie Workalemahu, Kari E. North, David J. Porteous, Peter Vollenweider, Kennet Harald, Claire Bellis, Serena Sanna, Nicholas D. Hastie, Robert J. Klein, Marie-Claude Vohl, Ruth J. F. Loos, Jian Gong, Igor Rudan, Unhee Lim, Christopher A. Haiman, Martina Müller-Nurasyid, Konstantin Strauch, Mark A. Sarzynski, Albert V. Smith, Mark Walker, Tapani Ebeling, Göran Hallmans, Nicole Dueker, Caroline S. Fox, Sven Bergmann, Keri L. Monda, Thorkild I. A. Sørensen, André G. Uitterlinden, Johanne Marie Justesen, Aki S. Havulinna, Torben Hansen, Ivana Kolcic, Cecilia M. Lindgren, Marcel den Hoed, Richard N. Bergman, Mariaelisa Graff, Alan R. Shuldiner, Dorota Pasko, James F. Wilson, John Whitfield, Joel Eriksson, Jaspal S. Kooner, Mette Hollensted, Winfried März, Gonçalo R. Abecasis, Weihua Zhang, Harold Snieder, Rajesh Rawal, Tao Huang, Åsa Johansson, Lydia Quaye, Ying Wu, Benjamin Lehne, Matthias Nauck, Caroline Hayward, Linda S. Adair, Michel Marre, Tanguy Corre, Alan James, Frida Renström, Jian'an Luan, Zoltán Kutalik, Kurt Lohman, Jennifer A. Smith, Mao Fu, Jennifer L. Bragg-Gresham, Tamara B. Harris, Claudia Langenberg, Tõnu Esko, Mattias Lorentzon, Ken K. Ong, Blair H. Smith, Fabio Busonero, Alan F. Wright, Gemma Cadby, Andrew D. Johnson, Steve Buyske, Anubha Mahajan, Antonella Mulas, Gérard Waeber, Lori L. Bonnycastle, Daniel I. Chasman, Jennie Hui, Audrey Y. Chu, Uwe Völker, Albertine J. Oldehinkel, Jing Hua Zhao, Robert A. Scott, Ilja M. Nolte, Loic LeMarchand, Yu-Ching Cheng, David P. Strachan, Jie Huang, Gerard van Grootheest, John D. Eicher, Marcus E. Kleber, Francis S. Collins, Cornelia M. van Duijn, Timothy M. Frayling, Pau Navarro, Leo-Pekka Lyytikäinen, Cinzia Sarti, Paul M. Ridker, John-Olov Jansson, Shafqat Ahmad, Philippe Froguel, Albert Hofman, Inga Prokopenko, Vilmundur Gudnason, Anne U. Jackson, David R. Weir, Lyle J. Palmer, Alexander Teumer, Ulf Gyllensten, Mette Aadahl, Niels Grarup, Beverley Balkau, Oluf Pedersen, Cornelia Huth, Dorret I. Boomsma, Harry Campbell, Charlotte Huppertz, Ingrid B. Borecki, Juha Auvinen, Soren Snitker, Yuri Milaneschi, Iris M. Heid, Barbara Thorand, Wouter J. Peyrot, Lavinia Paternoster, Sian-Tsung Tan, Anne E. Justice, Dena G. Hernandez, Marcus Dörr, Nicholas J. Wareham, Marilyn C. Cornelis, Claes Ohlsson, Amy J. Swift, Ozren Polasek, Brenda W.J.H. Penninx, James E. Hayes, Stephanie A. Bien, Jana V. van Vliet-Ostaptchouk, Eric Boerwinkle, Louis Pérusse, Peter J. van der Most, Ulrike Peters, Pirjo Komulainen, Lynne J. Hocking, Catharina A. Hartman, William R. Scott, Jeffrey R. O'Connell, Stefania Bandinelli, Tuomo Rankinen, Timo A. Lakka, Leena Kinnunen, Markus Perola, John Blangero, Sharon L.R. Kardia, Veronique Vitart, Mika Kähönen, Marie Neergaard Harder, Diana Kuh, Kai Savonen, Kristin L. Young, Jeremiah Perez, Nina Hutri-Kähönen, George Davey Smith, Toshiko Tanaka, Barbara Sternfeld, Jennifer A. Nettleton, Jouke-Jan Hottenga, Christian Gieger, Gonneke Willemsen, Soren Brage, Mika Kivimäki, Lucia A. Hindorff, Steve Sidney, Tarunveer S. Ahluwalia, Liesbeth Vandenput, Loic Yengo, Markku Laakso, Yongmei Liu, Arthur W. Musk, Harald Grallert, Kirsti Kvaløy, Rainer Rauramaa, Satu Männistö, Tuomas O. Kilpeläinen, M. Carola Zillikens, Hannu Puolijoki, Luting Xue, Oddgeir L. Holmens, Sandosh Padmanabhan, Inês Barroso, Ching-Ti Liu, L. Adrienne Cupples, Judith B. Borja, Karen L. Mohlke, Matthias Olden, Henry Völzke, Myriam Fornage, Michael Boehnke, Pedro Marques-Vidal, John Beilby, Fernando Rivadeneira, Maija Hassinen, Najaf Amin, Kristian Hveem, Gudny Eiriksdottir, Lenore J. Launer, Johanna Kuusisto, Dorothée Thuillier, Heather M. Stringham, Sven Gläser, Min A. Jhun, Marjo-Riitta Järvelin, Niha Zubair, Annette Peters, Llilda Barata, Paula J. Griffin, Markus Juonala, Wei Zhao, Andres Metspalu, Christina Holzapfel, Lawrence F. Bielak, Thomas W. Winkler, Alena Stančáková, Anke Tönjes, Narisu Narisu, David Hadley, Peter S. Chines, Andrew Wong, Günther Silbernagel, Kati Kristiansson, Eco J. C. de Geus, Grant W. Montgomery, Elise Lim, Laura J. Rasmussen-Torvik, Terho Lehtimäki, Heikki A. Koistinen, Meena Kumari, Qibin Qi, Ayse Demirkan, Francesco Cucca, Allan Linneberg, Reija Männikkö, Jonathan Marten, Olli T. Raitakari, Mary F. Feitosa, Paul W. Franks, Kristine Færch, Mark I. McCarthy, Marleen H.M. de Moor, Joel N. Hirschhorn, Toomas Haller

المساهمون: Graff, Mariaelisa [0000-0001-6380-1735], Young, Kristin L [0000-0003-0070-6145], Winkler, Thomas W [0000-0003-0292-5421], Heard-Costa, Nancy L [0000-0001-9730-0306], Renström, Frida [0000-0001-6053-298X], Barroso, Inês [0000-0001-5800-4520], Strachan, David P [0000-0001-7854-1366], Liu, Ching-Ti [0000-0002-0703-0742], Klein, Robert J [0000-0003-3539-5391], Apollo - University of Cambridge Repository, University of Helsinki, Institute for Molecular Medicine Finland, Quantitative Genetics, Clinicum, Department of Medicine, Endokrinologian yksikkö, HUS Internal Medicine and Rehabilitation, Complex Disease Genetics, Læknadeild (HÍ), Faculty of Medicine (UI), Heilbrigðisvísindasvið (HÍ), School of Health Sciences (UI), Háskóli Íslands, University of Iceland, CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium, Edwards, Todd L., Biological Psychology, APH - Mental Health, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Clinical Child and Family Studies, APH - Methodology, School of Medicine / Biomedicine, Public and occupational health, Psychiatry, Amsterdam Neuroscience - Complex Trait Genetics, APH - Digital Health, Life Course Epidemiology (LCE), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Center for Liver, Digestive and Metabolic Diseases (CLDM), Epidemiology, Medical Microbiology & Infectious Diseases, Erasmus MC other, Child and Adolescent Psychiatry / Psychology, Internal Medicine

المصدر: PLoS Genet. 13:e1006528 (2017)
Graff, M, Davey Smith, G, Paternoster, L & Sorensen, T 2017, ' Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ', PLoS Genetics, vol. 13, no. 4, e1006528 . https://doi.org/10.1371/journal.pgen.1006528
13:e1006528
PLoS Genetics
PLoS Genetics, 13(4)
PLoS genetics, vol. 13, no. 4, pp. e1006528
Graff, M, Scott, R A, Justice, A E, Young, K L, Feitosa, M F, Barata, L, Winkler, T W, Chu, A Y, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-costa, N L, Den Hoed, M, Ahluwalia, T S, Qi, Q, Ngwa, J S, Renström, F, Quaye, L, Eicher, J D, Hayes, J E, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, J E, Zhang, W, Zhao, W, Griffin, P J, Haller, T, Ahmad, S, Marques-vidal, P M, Bien, S, Yengo, L, Teumer, A, Smith, A V, Kumari, M, Harder, M N, Justesen, J M, Kleber, M E, Hollensted, M, Lohman, K, Rivera, N V, Whitfield, J B, Zhao, J H, Stringham, H M, Lyytikäinen, L, Huppertz, C, Willemsen, G, Peyrot, W J, Wu, Y, Kristiansson, K, Demirkan, A, Fornage, M, Hassinen, M, Bielak, L F, Cadby, G, Tanaka, T, Mägi, R, Van Der Most, P J, Jackson, A U, Bragg-gresham, J L, Vitart, V, Marten, J, Navarro, P, Bellis, C, Pasko, D, Johansson, Å, Snitker, S, Cheng, Y, Eriksson, J, Lim, U, Aadahl, M, Adair, L S, Amin, N, Balkau, B, Auvinen, J, Beilby, J, Bergman, R N, Bergmann, S, Bertoni, A G, Blangero, J, Bonnefond, A, Bonnycastle, L L, Borja, J B, Brage, S, Busonero, F, Buyske, S, Campbell, H, Chines, P S, Collins, F S, Corre, T, Smith, G D, Delgado, G E, Dueker, N, Dörr, M, Ebeling, T, Eiriksdottir, G, Esko, T, Faul, J D, Fu, M, Færch, K, Gieger, C, Gläser, S, Gong, J, Gordon-larsen, P, Grallert, H, Grammer, T B, Grarup, N, Van Grootheest, G, Harald, K, Hastie, N D, Havulinna, A S, Hernandez, D, Hindorff, L, Hocking, L J, Holmens, O L, Holzapfel, C, Hottenga, J J, Huang, J, Huang, T, Hui, J, Huth, C, Hutri-kähönen, N, James, A L, Jansson, J, Jhun, M A, Juonala, M, Kinnunen, L, Koistinen, H A, Kolcic, I, Komulainen, P, Kuusisto, J, Kvaløy, K, Kähönen, M, Lakka, T A, Launer, L J, Lehne, B, Lindgren, C M, Lorentzon, M, Luben, R, Marre, M, Milaneschi, Y, Monda, K L, Montgomery, G W, De Moor, M H M, Mulas, A, Müller-nurasyid, M, Musk, A W, Männikkö, R, Männistö, S, Narisu, N, Nauck, M, Nettleton, J A, Nolte, I M, Oldehinkel, A J, Olden, M, Ong, K K, Padmanabhan, S, Paternoster, L, Perez, J, Perola, M, Peters, A, Peters, U, Peyser, P A, Prokopenko, I, Puolijoki, H, Raitakari, O T, Rankinen, T, Rasmussen-torvik, L J, Rawal, R, Ridker, P M, Rose, L M, Rudan, I, Sarti, C, Sarzynski, M A, Savonen, K, Scott, W R, Sanna, S, Shuldiner, A R, Sidney, S, Silbernagel, G, Smith, B H, Smith, J A, Snieder, H, Stančáková, A, Sternfeld, B, Swift, A J, Tammelin, T, Tan, S, Thorand, B, Thuillier, D, Vandenput, L, Vestergaard, H, Van Vliet-ostaptchouk, J V, Vohl, M, Völker, U, Waeber, G, Walker, M, Wild, S, Wong, A, Wright, A F, Zillikens, M C, Zubair, N, Haiman, C A, Lemarchand, L, Gyllensten, U, Ohlsson, C, Hofman, A, Rivadeneira, F, Uitterlinden, A G, Pérusse, L, Wilson, J F, Hayward, C, Polasek, O, Cucca, F, Hveem, K, Hartman, C A, Tönjes, A, Bandinelli, S, Palmer, L J, Kardia, S L R, Rauramaa, R, Sørensen, T I A, Tuomilehto, J, Salomaa, V, Penninx, B W J H, De Geus, E J C, Boomsma, D I, Lehtimäki, T, Mangino, M, Laakso, M, Bouchard, C, Martin, N G, Kuh, D, Liu, Y, Linneberg, A, März, W, Strauch, K, Kivimäki, M, Harris, T B, Gudnason, V, Völzke, H, Qi, L, Järvelin, M, Chambers, J C, Kooner, J S, Froguel, P, Kooperberg, C, Vollenweider, P, Hallmans, G, Hansen, T, Pedersen, O, Metspalu, A, Wareham, N J, Langenberg, C, Weir, D R, Porteous, D J, Boerwinkle, E, Chasman, D I, Abecasis, G R, Barroso, I, Mccarthy, M I, Frayling, T M, O’connell, J R, Van Duijn, C M, Boehnke, M, Heid, I M, Mohlke, K L, Strachan, D P, Fox, C S, Liu, C, Hirschhorn, J N, Klein, R J, Johnson, A D, Borecki, I B, Franks, P W, North, K E, Cupples, L A, Loos, R J F, Kilpeläinen, T O & Edwards, T L (ed.) 2017, ' Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ', PLoS Genetics, vol. 13, no. 4, pp. e1006528 . https://doi.org/10.1371/journal.pgen.1006528
PLoS Genetics, Vol 13, Iss 4, p e1006528 (2017)
Graff, M, Scott, R A, Justice, A E, Young, K L, Feitosa, M F, Barata, L, Winkler, T W, Chu, A Y, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-Costa, N L, den Hoed, M, Ahluwalia, T S, Qi, Q, Ngwa, J S, Renström, F, Quaye, L, Eicher, J D, Hayes, J E, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, J E, Zhang, W, Zhao, W, Griffin, P J, Haller, T, Ahmad, S, Marques-Vidal, P M, Bien, S, Yengo, L, Teumer, A, Smith, A V, Kumari, M, Harder, M N, Justesen, J M, Kleber, M E, Hollensted, M, Lohman, K, Huppertz, C, Willemsen, G, Hottenga, J J, Milaneschi, Y, De Moor, M H M, Penninx, B W J H, de Geus, E J C, Boomsma, D I & CHARGE Consortium 2017, ' Genome-wide physical activity interactions in adiposity-A meta-analysis of 200,452 adults ', PLoS Genetics, vol. 13, no. 4, e1006528, pp. e1006528 . https://doi.org/10.1371/journal.pgen.1006528
PLoS Genetics, 13(4):e1006528. Public Library of Science
Graff, M, Scott, R A, Justice, A E, Young, K L, Feitosa, M F, Barata, L, Winkler, T W, Chu, A Y, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-Costa, N L, den Hoed, M, Ahluwalia, T S, Qi, Q, Ngwa, J S, Renström, F, Quaye, L, Eicher, J D, Hayes, J E, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, J E, Zhang, W, Zhao, W, Griffin, P J, Haller, T, Ahmad, S, Marques-Vidal, P M, Bien, S, Yengo, L, Teumer, A, Smith, A V, Kumari, M, Harder, M N, Justesen, J M, Kleber, M E, Hollensted, M, Lohman, K, Rivera, N V, Whitfield, J B, Zhao, J H, Huppertz, C, Peyrot, W J, van Grootheest, G, Milaneschi, Y, Penninx, B W J H, CHARGE Consortium, EPIC-InterAct Consortium & PAGE Consortium 2017, ' Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ', PLoS Genetics, vol. 13, no. 4, e1006528 . https://doi.org/10.1371/journal.pgen.1006528
PLoS genetics, 13(4). PUBLIC LIBRARY SCIENCE
Graff, M, Scott, R A, Justice, A E, Young, K L, Feitosa, M F, Barata, L, Winkler, T W, Chu, A Y, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-Costa, N L, den Hoed, M, Ahluwalia, T S, Qi, Q, Ngwa, J S, Renström, F, Quaye, L, Eicher, J D, Hayes, J E, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, J E, Zhang, W, Zhao, W, Griffin, P J, Haller, T, Ahmad, S, Marques-Vidal, P M, Bien, S, Yengo, L, Teumer, A, Smith, A V, Kumari, M, Harder, M N, Justesen, J M, Kleber, M E, Hollensted, M, Lohman, K, Rivera, N V, Whitfield, J B, Zhao, J H, Stringham, H M & Lyytikäinen, L P & Huppertz, C & Willemsen, G & Peyrot, W J 2017, ' Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ', PLoS Genetics, vol. 13, no. 4, e1006528 . https://doi.org/10.1371/journal.pgen.1006528
Graff, M, Scott, R A, Justice, A E, Young, K L, Feitosa, M F, Barata, L, Winkler, T W, Chu, A Y, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-Costa, N L, den Hoed, M, Ahluwalia, T S, Qi, Q, Ngwa, J S, Renström, F, Quaye, L, Eicher, J D, Hayes, J E, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, J E, Zhang, W, Zhao, W, Griffin, P J, Haller, T, Ahmad, S, Marques-Vidal, P M, Bien, S, Yengo, L, Teumer, A, Smith, A V, Kumari, M, Harder, M N, Justesen, J M, Kleber, M E, Hollensted, M, Aadahl, M, Færch, K, Grarup, N, Vestergaard, H, Sørensen, T I A, Linneberg, A, Hansen, T, Pedersen, O, Loos, R J F, Kilpeläinen, T O, CHARGE Consortium, EPIC-InterAct Consortium & PAGE Consortium 2017, ' Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ', PLOS Genetics, vol. 13, no. 4, e1006528 . https://doi.org/10.1371/journal.pgen.1006528
PLoS Genetics (online), 13(4):e1006528. Public Library of Science

مصطلحات موضوعية: Netherlands Twin Register (NTR), Epigenomics, Male, Genome-wide association study, genome, obesity, BMI, Body Mass Index, 0302 clinical medicine, Cell Signaling, Public and Occupational Health, GENE-EXPRESSION, Adiposity, Genetics & Heredity, ADIPOCYTE DIFFERENTIATION, 1184 Genetics, developmental biology, physiology, Genomics, Functional Genomics, 3. Good health, Meta-analysis, Physical Sciences, REACTIVE PROTEIN-LEVELS, Waist Circumference, Statistics (Mathematics), Waist, Genotype, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Single-nucleotide polymorphism, Locus (genetics), BINDING PROTEIN, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Genome-Wide Association Studies, Genetics, Humans, Statistical Methods, Molecular Biology, Exercise, Ecology, Evolution, Behavior and Systematics, 0604 Genetics, Science & Technology, ASSOCIATION METAANALYSIS, Physical activity, ta1184, Biology and Life Sciences, Computational Biology, Physical Activity, 030104 developmental biology, Genetic Loci, Body mass index, Mathematics, 030217 neurology & neurosurgery, Meta-Analysis, Developmental Biology, BODY-MASS INDEX, IDENTICAL-TWINS, ACTIVITY QUESTIONNAIRES, FAT DISTRIBUTION, FOOD-INTAKE, 0301 basic medicine, Cancer Research, Medicin och hälsovetenskap, Offita, Physiology, FTO gene, Genome-wide association studies, Medical and Health Sciences, Mathematical and Statistical Techniques, Waist–hip ratio, Medicine and Health Sciences, Genetics (clinical), Public Health, Global Health, Social Medicine and Epidemiology, Physiological Parameters, Female, Genomic Signal Processing, Life Sciences & Biomedicine, Research Article, Signal Transduction, lcsh:QH426-470, Biology, Research and Analysis Methods, Hreyfing (heilsurækt), Journal Article, Erfðafræði, Genetic Predisposition to Disease, Obesity, Waist-Hip Ratio, Body Weight, Human Genetics, Cell Biology, Rannsóknir, Genome Analysis, lcsh:Genetics, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, 3111 Biomedicine, Genome-Wide Association Study

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333f0d27bc71a75a972b929209ed0265
https://www.repository.cam.ac.uk/handle/1810/266503

المؤلفون: Antti J. Kangas, Joris Deelen, Rajesh Rawal, Tuulia Tynkkynen, Anton J. M. de Craen, Gonneke Willemsen, Antti Jula, Taru Tukiainen, Anika A. M. Vaarhorst, Aswin Verhoeven, Johannes Kettunen, Cornelia M. van Duijn, Samuli Ripatti, Ko Willems van Dijk, René Pool, Pasi Soininen, Stefan Blankenberg, Mika Kähönen, Qin Wang, Markus Perola, Marjo-Riitta Järvelin, Markku J. Savolainen, Mika Ala-Korpela, Antti-Pekka Sarin, Veikko Salomaa, Najaf Amin, Terho Lehtimäki, Jaakko Kaprio, Melanie Waldenberger, P. Eline Slagboom, Mika Tiainen, Leo-Pekka Lyytikäinen, Jouke-Jan Hottenga, Jorma Viikari, Tanja Zeller, Toomas Haller, Johan G. Eriksson, Ayse Demirkan, Olli T. Raitakari, Elisabeth M. van Leeuwen, Evelin Mihailov, Marian Beekman, Harmen H.M. Draisma, Andres Metspalu, Matti Pirinen, Dorret I. Boomsma, Christian Gieger, Richard J. Rose, Peter Würtz, Tõnu Esko

المساهمون: Epidemiology, Institute for Molecular Medicine Finland, Clinicum, Johan Eriksson / Principal Investigator, Department of General Practice and Primary Health Care, Jaakko Kaprio / Principal Investigator, Department of Public Health, Samuli Olli Ripatti / Principal Investigator, Biostatistics Helsinki, Quantitative Genetics, Complex Disease Genetics, Genetic Epidemiology, Statistical and population genetics, Biological Psychology, EMGO+ - Lifestyle, Overweight and Diabetes, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep

المصدر: Kettunen, J, Demirkan, A, Würtz, P, Draisma, H H M, Haller, T, Rawal, R, Vaarhorst, A A M, Kangas, A J, Lyytikäinen, L P, Pirinen, M, Pool, R, Sarin, A-P, Soininen, P, Tukiainen, T, Wang, Q, Tiainen, M, Tynkkynen, T, Amin, N, Zeller, T, Beekman, M, Deelen, J, Willems van Dijk, K, Esko, T, Hottenga, J J, van Leeuwen, E M, Lehtimäki, T, Mihailov, E, Rose, R J, de Craen, A J, Gieger, C, Kähönen, M, Perola, M, Blankenberg, S, Savolainen, M J, Verhoeven, A, Viikari, J, Willemsen, G, Boomsma, D I, van Duijn, C M, Eriksson, J, Jula, A, Järvelin, M R, Kaprio, J, Metspalu, A, Raitakari, O, Salomaa, V, Slagboom, P E, Waldenberger, M, Ripatti, S & Ala-Korpela, M 2016, ' Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA ', Nature Communications, vol. 7, 11122 . https://doi.org/10.1038/ncomms11122
Nat. Commun. 7:11122 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications, 7
Nat Commun
Nature Communications, 7:11122. Nature Publishing Group
Nature Communications
Kettunen, J & Ala-Korpela, M 2016, ' Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA ', Nature Communications, vol. 7, 11122 . https://doi.org/10.1038/ncomms11122

مصطلحات موضوعية: Male, 0301 basic medicine, Netherlands Twin Register (NTR), Magnetic Resonance Spectroscopy, General Physics and Astronomy, Genome-wide association study, Lipoproteins, VLDL, Genome-wide association studies, THERAPY, RISK, Genetics, Multidisciplinary, JUPITER TRIAL, Chromosome Mapping, Mendelian Randomization Analysis, ASSOCIATION, Lipoprotein(a), Middle Aged, 3. Good health, Multidisciplinary Sciences, Cardiovascular Diseases, Science & Technology - Other Topics, CORONARY-ARTERY-DISEASE, Medical genetics, Female, Adult, medicine.medical_specialty, medical genetics, Science, Locus (genetics), Biology, Article, General Biochemistry, Genetics and Molecular Biology, JUSTIFICATION, Young Adult, 03 medical and health sciences, Metabolomics, SDG 3 - Good Health and Well-being, MD Multidisciplinary, Mendelian randomization, medicine, Humans, Genetic Predisposition to Disease, EVALUATING ROSUVASTATIN, Triglycerides, Aged, Genetic association, INTERVENTION TRIAL, Science & Technology, General Chemistry, ta3121, 030104 developmental biology, 3121 General medicine, internal medicine and other clinical medicine, biology.protein, GENETIC-DETERMINANTS, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95be28139271a8ed6d98db51c25375b0
https://research.vu.nl/en/publications/ec4670e0-907c-4528-916e-039a0a08e169

المؤلفون: Christian Herder, Thomas Illig, Gonneke Willemsen, Yixue Li, Tao Xu, Anne S. Quante, Toomas Haller, Janina S. Ried, Konstantin Strauch, Ana C. Messias, Werner Roemisch-Margl, Jerzy Adamski, Barbara Thorand, Martin Hrabé de Angelis, Ying He, Ayse Demirkan, Gabi Kastenmüller, Katarina Kasa, Annette Peters, Wolfgang Rathmann, Jonathan Adam, Tommaso Panni, Zhonghao Yu, Markus Rotter, Gisela Fobo, Bernd Stratmann, Dorret I. Boomsma, Karsten Suhre, Shen Chi, Michael Roden, Thomas Meitinger, Cornelia M. van Duijn, Ko Willems van Dijk, René Pool, Cornelia Prehn, Monica Campillos, Christa Meisinger, Stefan Brandmaier, Christian Gieger, Andres Metspalu, Christina Holzapfel, Harmen H.M. Draisma, Thomas Hankemeier, Margit Heier, H.-Erich Wichmann, Rui Wang-Sattler, Renee Stark, Andreas Ruepp

المساهمون: Biological Psychology, Neuroscience Campus Amsterdam - Neurobiology of Mental Health, EMGO+ - Lifestyle, Overweight and Diabetes, Dermatology, Epidemiology

المصدر: Xu, T, Brandmaier, S, Messias, A C, Herder, C, Draisma, H H M, Demirkan, A, Yu, Z, Ried, J S, Haller, T, Heier, M, Campillos, M, Fobo, G, Stark, R, Holzapfel, C, Adam, J, Chi, S, Rotter, M, Panni, T, Quante, A S, He, Y, Prehn, C, Roemisch-Margl, W, Kastenmüller, G, Willemsen, G, Pool, R, Kasa, K, Willems van Dijk, K, Hankemeier, T, Meisinger, C, Thorand, B, Ruepp, A, Hrabé de Angelis, M, Li, Y, Wichmann, H-E, Stratmann, B, Strauch, K, Metspalu, A, Gieger, C, Suhre, K, Adamski, J, Illig, T, Rathmann, W, Roden, M, Peters, A, van Duijn, C M, Boomsma, D I, Meitinger, T & Wang-Sattler, R 2015, ' Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes ', Diabetes Care, vol. 38, no. 10, pp. 1858-1867 . https://doi.org/10.2337/dc15-0658
Diabetes Care 38, 1858-1867 (2015)
Diabetes Care, 38(10), 1858-1867. American Diabetes Association Inc.
Diabetes Care
Diabetes Care, 38(10), 1858-1867

مصطلحات موضوعية: Fatty Acid Desaturases, Male, Netherlands Twin Register (NTR), medicine.medical_specialty, Genotype, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Metabolite, Population, Blood lipids, Type 2 diabetes, chemistry.chemical_compound, Delta-5 Fatty Acid Desaturase, SDG 3 - Good Health and Well-being, Risk Factors, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Metabolomics, education, Aged, Advanced and Specialized Nursing, education.field_of_study, Cholesterol, business.industry, AMPK, nutritional and metabolic diseases, Cholesterol, LDL, Fasting, Genomics, Middle Aged, Lipid Metabolism, medicine.disease, Metformin, 3. Good health, Cross-Sectional Studies, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Female, business, Diabetic Angiopathies, medicine.drug

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c6b4744d74006b2e8c9b4fb3c46326
https://hdl.handle.net/1887/108271

المؤلفون: Jacqueline C.M. Witteman, Nicole Probst-Hensch, Gail Davies, Anna Köttgen, Qunyuan Zhang, Pio D'Adamo, Nicholas G. Martin, Silvia Tore, Stephan J. L. Bakker, Gian Andri Thun, Cinzia Sala, Peter P. Pramstaller, Tamara B. Harris, Aaron Isaacs, Sheila Ulivi, Rossella Sorice, Xuan Liu, Andrew A. Hicks, Henry Völzke, Daniela Ruggiero, Arnold von Eckardstein, Yukinori Okada, Andres Metspalu, Jeffrey Metter, Serena Sanna, Jennifer E. Huffman, Philipp S. Wild, Florian Ernst, Eva Albrecht, Mary F. Feitosa, Claudia Schurmann, Kathrin Budde, Veikko Salomaa, Darina Czamara, Elizabeth G. Holliday, Marcel Bruinenberg, Laura Portas, Maris Laan, Alan J. Gow, Caroline Hayward, Tim D. Spector, Ozren Polasek, Ilja M. Nolte, Rodney J. Scott, Massimo Mangino, David S. Siscovick, Nilesh J. Samani, Toomas Haller, Laura Frogheri, A. Jula, Mika Kähönen, Bruce H. R. Wolffenbuttel, Caroline S. Fox, David R. Jacobs, Julia Shi, Yusuke Nakamura, Daniel I. Chasman, Fabian J. Theis, Alan F. Wright, Ayse Demirkan, Francesco Cucca, Paolo Gasparini, Paul M. Ridker, Olli T. Raitakari, Daniela Toniolo, Maristella Steri, Mario Pirastu, Susan Campbell, Maksim Struchalin, So-Youn Shin, Mark J. Caulfield, H.-Erich Wichmann, Grant W. Montgomery, Åsa Johansson, Alexander Teumer, Ulf Gyllensten, Robert M. Plenge, Michel Burnier, Michael Schallert, Jan Krumsiek, Jing Hua Zhao, Andres Salumets, Poorva Mudgal, Anke Tönjes, James F. Meschia, Gauti Kjartan Gislason, Perttu Salo, Angela Döring, Afshin Parsa, Vilmundur Gudnason, Patrick F. McArdle, Rita P. S. Middelberg, W. H. Linda Kao, Aldi Kraja, Christopher Oldmeadow, Adrienne Tin, Loic Yengo, Murielle Bochud, Gerjan Navis, Christian Gieger, Toshiko Tanaka, Cornelia M. van Duijn, Samuli Ripatti, Terho Lehtimäki, Claudia Langenberg, Bernhard O. Boehm, Conall M. O'Seaghdha, Eric Boerwinkle, Nicole Soranzo, Tõnu Esko, Susan M. Farrington, Mike A. Nalls, John F. Peden, Hyon K. Choi, Anuj Goel, Andrew D. Johnson, Norman Klopp, Anne Grotevendt, Halit Ongen, Marcus E. Kleber, Myriam Fornage, Malcolm G. Dunlop, Igor Rudan, Federico Murgia, Beverley Balkau, Jorma Viikari, Christopher P. Nelson, Gérard Waeber, Lenore J. Launer, Ivana Persico, Inga Prokopenko, Guo Li, Tatijana Zemunik, Elisabetta Trabetti, Tanja Zeller, Hugh Watkins, Qiong Yang, James F. Wilson, Peter Vollenweider, Veronique Vitart, Markus Perola, Nicola Pirastu, Olivier Devuyst, Irene Mateo Leach, John Attia, Bruce M. Psaty, Nicholas J. Wareham, Susanne Lucae, Josef Coresh, Ingrid B. Borecki, Claudia Hundertmark, Weihua Zhang, Luigi Ferrucci, Jaspal S. Kooner, Stefan Kloiber, Lynda M. Rose, Naoyuki Kamatani, Zoltán Kutalik, Giovanni Malerba, Ian J. Deary, Albert V. Smith, Helena Schmidt, Eva Lattka, Philippe Froguel, Harry Campbell, Medea Imboden, Antonio Lupo, Angelo L. Gaffo, Vasiliki Lagou, Alan R. Shuldiner, John Whitfield, Abbas Dehghan, Winfried März, Elin Org, Albert Hofman, Margus Viigimaa, Konstantin Strauch, Toshihiro Tanaka, Andrew B. Singleton, Stefania Bandinelli, Christian Hengstenberg, Xinzhong Li, Wiek H. van Gilst, Pim van der Harst, Giorgio Pistis, Jerome I. Rotter, Maria Grazia Piras, Gary C. Curhan, Brenda W.J.H. Penninx, Ramaiah Nagaraja, Nabila Bouatia-Naji, Christian Müller, Ronald P. Stolk, Pau Navarro, Lorna M. Lopez, Ruth J. F. Loos, Albert Tenesa, Johannes H. Smit, Peter Kraft, Giovanni Gambaro, Sarah H. Wild, Patricia B. Munroe, André G. Uitterlinden, Ivana Kolcic, Bernhard R. Winkelmann, Pankaj Sharma, John C. Chambers, Nicholas D. Hastie, Matthias Nauck, Harold Snieder, Michael Stumvoll, Reinhold Schmidt, Hans L. Hillege, Kiang Liu, Fernando Rivadeneira, Owen M. Woodward, Morris J. Brown, Margus Putku, Sabine Schipf, Mirna Kirin, Kay-Tee Khaw, Melanie Waldenberger, Evropi Theodoratou, Marina Ciullo, Michiaki Kubo

المساهمون: Köttgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, Cm, Haller, T, Yang, Q, Tanaka, T, Johnson, Ad, Kutalik, Z, Smith, Av, Shi, J, Struchalin, M, Middelberg, Rp, Brown, Mj, Gaffo, Al, Pirastu, Nicola, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, Jh, Demirkan, A, Feitosa, Mf, Liu, X, Malerba, G, Lopez, Lm, van der Harst, P, Li, X, Kleber, Me, Hicks, Aa, Nolte, Im, Johansson, A, Murgia, F, Wild, Sh, Bakker, Sj, Peden, Jf, Dehghan, A, Steri, M, Tenesa, A, Lagou, V, Salo, P, Mangino, M, Rose, Lm, Lehtimäki, T, Woodward, Om, Okada, Y, Tin, A, Müller, C, Oldmeadow, C, Putku, M, Czamara, D, Kraft, P, Frogheri, L, Thun, Ga, Grotevendt, A, Gislason, Gk, Harris, Tb, Launer, Lj, Mcardle, P, Shuldiner, Ar, Boerwinkle, E, Coresh, J, Schmidt, H, Schallert, M, Martin, Ng, Montgomery, Gw, Kubo, M, Nakamura, Y, Munroe, Pb, Samani, Nj, Jacobs DR, Jr, Liu, K, D'Adamo, ADAMO PIO, Ulivi, S, Rotter, Ji, Psaty, Bm, Vollenweider, P, Waeber, G, Campbell, S, Devuyst, O, Navarro, P, Kolcic, I, Hastie, N, Balkau, B, Froguel, P, Esko, T, Salumets, A, Khaw, Kt, Langenberg, C, Wareham, Nj, Isaacs, A, Kraja, A, Zhang, Q, Wild, P, Scott, Rj, Holliday, Eg, Org, E, Viigimaa, M, Bandinelli, S, Metter, Je, Lupo, A, Trabetti, E, Sorice, R, Döring, A, Lattka, E, Strauch, K, Theis, F, Waldenberger, M, Wichmann, He, Davies, G, Gow, Aj, Bruinenberg, M, Stolk, Rp, Kooner, J, Zhang, W, Winkelmann, Br, Boehm, Bo, Lucae, S, Penninx, Bw, Smit, Jh, Curhan, G, Mudgal, P, Plenge, Rm, Portas, L, Persico, I, Kirin, M, Wilson, Jf, Leach, Im, van Gilst, Wh, Goel, A, Ongen, H, Hofman, A, Rivadeneira, F, Uitterlinden, Ag, Imboden, M, von Eckardstein, A, Cucca, F, Nagaraja, R, Piras, Mg, Nauck, M, Schurmann, C, Budde, K, Ernst, F, Farrington, Sm, Theodoratou, E, Prokopenko, I, Stumvoll, M, Jula, A, Perola, M, Salomaa, V, Shin, Sy, Spector, Td, Sala, C, Ridker, Pm, Kähönen, M, Viikari, J, Hengstenberg, C, Nelson, Cp, Meschia, Jf, Nalls, Ma, Sharma, P, Singleton, Ab, Kamatani, N, Zeller, T, Burnier, M, Attia, J, Laan, M, Klopp, N, Hillege, Hl, Kloiber, S, Choi, H, Pirastu, M, Tore, S, Probst Hensch, Nm, Völzke, H, Gudnason, V, Parsa, A, Schmidt, R, Whitfield, Jb, Fornage, M, Gasparini, Paolo, Siscovick, D, Polašek, O, Campbell, H, Rudan, I, Bouatia Naji, N, Metspalu, A, Loos, Rj, van Duijn, Cm, Borecki, Ib, Ferrucci, L, Gambaro, G, Deary, Ij, Wolffenbuttel, Bh, Chambers, Jc, März, W, Pramstaller, Pp, Snieder, H, Gyllensten, U, Wright, Af, Navis, G, Watkins, H, Witteman, Jc, Sanna, S, Schipf, S, Dunlop, Mg, Tönjes, A, Ripatti, S, Soranzo, N, Toniolo, D, Chasman, Di, Raitakari, O, Kao, Wh, Ciullo, M, Fox, C, Caulfield, M, Bochud, M, Gieger, C, LifeLines Cohort, Study, Cardiogram, Consortium, Diagram, Consortium, Icbp, Consortium, Magic, Consortium, Cardiovascular Centre (CVC), Life Course Epidemiology (LCE), Groningen Institute for Organ Transplantation (GIOT), Lifestyle Medicine (LM), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Center for Liver, Digestive and Metabolic Diseases (CLDM), Psychiatry, EMGO - Mental health, EMGO+ - Mental Health, LifeLines Cohort Study, CARDIoGRAM Consortium, DIAGRAM Consortium, ICBP Consortium, MAGIC Consortium, Epidemiology, Public Health, Internal Medicine

المصدر: Nature Genetics, 45(2), 145-154. Nature Publishing Group
Nature Genetics
Nature Genetics, 45(2), 145-54. Nature Publishing Group
Kottgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J L, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X Z, Kleber, M E, Hicks, A A, Nolte, I M, Johansson, A, Murgia, F, Wild, S H, Bakker, S J L, Peden, J F, Dehghan, A, Steri, M, Tenesa, A, Lagou, V, Salo, P, Mangino, M, Rose, L M, Lehtimaki, T, Woodward, O M, Okada, Y, Tin, A, Muller, C, Oldmeadow, C, Putku, M, Czamara, D, Kraft, P, Frogheri, L, Thun, G A, Grotevendt, A, Gislason, G K, Harris, T B, Launer, L J, McArdle, P, Shuldiner, A R, Boerwinkle, E, Coresh, J, Schmidt, H, Schallert, M, Martin, N G, Montgomery, G W, Kubo, M, Nakamura, Y, Tanaka, T, Munroe, P B, Samani, N J, Jacobs, D R, Liu, K, d'Adamo, P, Ulivi, S, Rotter, J I, Psaty, B M, Vollenweider, P, Waeber, G, Campbell, S, Devuyst, O, Navarro, P, Kolcic, I, Hastie, N, Balkau, B, Froguel, P, Esko, T, Salumets, A, Khaw, K T, Langenberg, C, Wareham, N J, Isaacs, A, Kraja, A, Zhang, Q Y, Penninx, B W J H, Smit, J H, Bochud, M & Gieger, C 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Köttgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, C M, Haller, T, Yang, Q, Tanaka, T, Johnson, A D, Kutalik, Z, Smith, A V, Shi, J, Struchalin, M, Middelberg, R P S, Brown, M J, Gaffo, A L, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, J H, Demirkan, A, Feitosa, M F, Liu, X, Malerba, G, Lopez, L M, van der Harst, P, Li, X, Kleber, M E, Wild, S H, Tenesa, A, Navarro, P, Hastie, N, Davies, G, Gow, A J, Wilson, J F, Farrington, S M, Theodoratou, E, Polasek, O, Campbell, H, Rudan, I, Deary, I J & Wright, A F & Dunlop, M G 2013, ' Genome-wide association analyses identify 18 new loci associated with serum urate concentrations ', Nature Genetics, vol. 45, no. 2, pp. 145-154 . https://doi.org/10.1038/ng.2500
Nature genetics
(2013). doi:10.1038/ng.2500
info:cnr-pdr/source/autori:Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Pola?ek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C./titolo:Genome-wide association analyses identify 18 new loci associated with serum urate concentrations/doi:10.1038%2Fng.2500/rivista:Nature genetics (Print)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nature Genetics; Vol 45
Nature Genetics, vol. 45, no. 2, pp. 145-154
Human Genetics, 45(2):145, 154-11. Springer-Verlag

مصطلحات موضوعية: Candidate gene, Inhibins/genetics, Genome-wide association study, GENETIC-LOCI, chemistry.chemical_compound, 0302 clinical medicine, serum urate, Gene Frequency, Gout/blood, association analysis, serum urate, Glucose/metabolism, Settore MED/14 - NEFROLOGIA, Hyperuricemia, serum, urate, gene, POPULATION, METABOLIC SYNDROME, Genetics, 0303 health sciences, education.field_of_study, biology, Polymorphism, Single Nucleotide/genetics, 3. Good health, HYPERURICEMIA, Genetic Loci/genetics, SLC22A12, Single Nucleotide/genetics, SNPs, Signal Transduction, MOLECULAR PHYSIOLOGY, serum urate concentrations, gout, genome-wide meta-analysis, European Continental Ancestry Group, Population, Polymorphism, Single Nucleotide, White People, Uric Acid/blood, serum urate concentrations, genome-wide meta-analysis, 03 medical and health sciences, SDG 3 - Good Health and Well-being, uric acid, medicine, Humans, Inhibins, Polymorphism, education, 030304 developmental biology, 030203 arthritis & rheumatology, Analysis of Variance, GOUT, IDENTIFICATION, TRANSPORTER, CARDIOVASCULAR-DISEASE RISK, ta3121, medicine.disease, association analysis, Gout, meta-analysis, Glucose, chemistry, Genetic Loci, genome-wide association studies, biology.protein, Signal Transduction/genetics, Uric acid, URIC-ACID LEVELS, Genome-Wide Association Study, SLC2A9

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc47fb35390519f51b5ff7c2f271262b
https://www.bib.irb.hr/639277

المؤلفون: Ching-Yu Cheng, Maria Schache, M. Kamran Ikram, Terri L. Young, Jeremy A. Guggenheim, Veronique Vitart, Stuart MacGregor, Virginie J.M. Verhoeven, Veluchamy A. Barathi, Jiemin Liao, Pirro G. Hysi, Joan E. Bailey-Wilson, Beate St. Pourcain, John P. Kemp, George McMahon, Nicholas J. Timpson, David M. Evans, Grant W. Montgomery, Aniket Mishra, Ya Xing Wang, Jie Jin Wang, Elena Rochtchina, Ozren Polasek, Alan F. Wright, Najaf Amin, Elisabeth M. van Leeuwen, James F. Wilson, Craig E. Pennell, Cornelia M. van Duijn, Paulus T.V.M. de Jong, Johannes R. Vingerling, Xin Zhou, Peng Chen, Ruoying Li, Wan-Ting Tay, Yingfeng Zheng, Merwyn Chew, Kathryn P. Burdon, Jamie E. Craig, Sudha K. Iyengar, Robert P. Igo, Jonathan H. Lass, Emily Y. Chew, Toomas Haller, Evelin Mihailov, Andres Metspalu, Juho Wedenoja, Claire L. Simpson, Robert Wojciechowski, René Höhn, Alireza Mirshahi, Tanja Zeller, Norbert Pfeiffer, Karl J. Lackner, Thomas Bettecken, Thomas Meitinger, Konrad Oexle, Mario Pirastu, Laura Portas, Abhishek Nag, Katie M. Williams, Ekaterina Yonova-Doing, Ronald Klein, Barbara E. Klein, S. Mohsen Hosseini, Andrew D. Paterson, Kari-Matti Makela, Terho Lehtimaki, Mika Kahonen, Olli Raitakari, Nagahisa Yoshimura, Fumihiko Matsuda, Li Jia Chen, Chi Pui Pang, Shea Ping Yip, Maurice K.H. Yap, Akira Meguro, Nobuhisa Mizuki, Hidetoshi Inoko, Paul J. Foster, Jing Hua Zhao, Eranga Vithana, E-Shyong Tai, Qiao Fan, Liang Xu, Harry Campbell, Brian Fleck, Igor Rudan, Tin Aung, Albert Hofman, André G. Uitterlinden, Goran Bencic, Chiea-Chuen Khor, Hannah Forward, Olavi Pärssinen, Paul Mitchell, Fernando Rivadeneira, Alex W. Hewitt, Cathy Williams, Ben A. Oostra, Yik-Ying Teo, Christopher J. Hammond, Dwight Stambolian, David A. Mackey, Caroline C.W. Klaver, Tien-Yin Wong, Seang-Mei Saw, Paul N. Baird, William Reinhart, Michael W. Belin, Robert L. Schultze, Todd Morason, Alan Sugar, Shahzad Mian, Hunson Kaz Soong, Kathryn Colby, Ula Jurkunas, Richard Yee, Mark Vital, Eduardo Alfonso, Carol Karp, Yunhee Lee, Sonia Yoo, Kristin Hammersmith, Elisabeth Cohen, Peter Laibson, Christopher Rapuano, Brandon Ayres, Christopher Croasdale, James Caudill, Sanjay Patel, Keith Baratz, William Bourne, Leo Maguire, Joel Sugar, Elmer Tu, Ali Djalilian, Vinod Mootha, James McCulley, Wayne Bowman, H. Dwight Cavanaugh, Steven Verity, David Verdier, Ann Renucci, Matt Oliva, Walter Rotkis, David R. Hardten, Ahmad Fahmy, Marlene Brown, Sherman Reeves, Elizabeth A. Davis, Richard Lindstrom, Scott Hauswirth, Stephen Hamilton, W. Barry Lee, Francis Price, Marianne Price, Kathleen Kelly, Faye Peters, Michael Shaughnessy, Thomas Steinemann, B.J. Dupps, David M. Meisler, Mark Mifflin, Randal Olson, Anthony Aldave, Gary Holland, Bartly J. Mondino, George Rosenwasser, Mark Gorovoy, Steven P. Dunn, David G. Heidemann, Mark Terry, Neda Shamie, Steven I. Rosenfeld, Brandon Suedekum, David Hwang, Donald Stone, James Chodosh, Paul G. Galentine, David Bardenstein, Katrina Goddard, Hemin Chin, Mark Mannis, Rohit Varma, Ingrid Borecki

المساهمون: Ophthalmology, Epidemiology, Internal Medicine, Clinical Genetics, Obstetrics & Gynecology, Netherlands Institute for Neuroscience (NIN)

المصدر: American Journal of Human Genetics, 93(2), 264-277. Cell Press
American journal of human genetics (Online) 93 (2013): 264–277. doi:10.1016/j.ajhg.2013.06.016
info:cnr-pdr/source/autori:Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; Fuchs' Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial%2FEpidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. Rahi JS, Hysi PG, Yoshimura N, Yamashiro K, Miyake M, Delcourt C, Maubaret C, Williams C, Guggenheim JA, Northstone K, Ring SM, Davey-Smith G, Craig JE, Burdon KP, Fogarty RD, Iyengar SK, Igo RP Jr, Chew E, Janmahasathian S, Iyengar SK, Igo RP Jr, Chew E, Janmahasathian S, Stambolian D, Bailey Wilson JE, MacGregor S, Lu Y, Jonas JB, Xu L, Saw SM, Baird PN, Rochtchina E, Mitchell P, Wang JJ, Jonas JB, Nangia V, Hayward C, Wright AF, Vitart V, Polasek O, Campbell H, Vitart V, Rudan I, Vatavuk Z, Vitart V, Paterson AD, Mohsen Hosseini S, Iyengar SK, Igo RP Jr, Fondran JR, Young TL, Feng S, Verhoeven VJ, Klaver CC, van Duijn CM, Metspalu A, Haller T, Mihailov E, Pärssinen O, Wedenoja J, Bailey Wilson JE, Wojciechowski R, Baird PN, Schache M, Pfeiffer N, Höhn R, Pang CP, Chen P, Meitinger T, Oexle K, Wegner A, Yoshimura N, Yamashiro K, Miyake M, Pärssinen O, Yip SP, Ho DW, Pirastu M, Murgia F, Portas L, Biino G, Wilson JF, Fleck B, Vitart V, Stambolian D, Bailey Wilson JE, Hewitt AW, Ang W, Verhoeven VJ, Klaver CC, van Duijn CM, Saw SM, Wong TY, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Saw SM, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Saw SM, Wong TY, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Saw SM, Wong TY, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Saw SM, Tai ES, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Saw SM, Teo YY, Fan Q, Cheng CY, Zhou X, Kamran Ikram M, Mackey DA, MacGregor S, Hammond CJ, Hysi PG, Deangelis MM, Morrison M, Zhou X, Chen W, Paterson AD, Mohsen Hosseini S, Mizuki N, Meguro A, Lehtimäki T, Mäkelä KM, Raitakari O, Kähönen M, Reinhart W, Belin MW, Schultze RL, Morason T, Sugar A, Mian S, Soong HK, Colby K, Jurkunas U, Yee R, Vital M, Alfonso E, Karp C, Lee Y, Yoo S, Hammersmith K, Cohen E, Laibson P, Rapuano C, Ayres B, Croasdale C, Caudill J, Patel S, Baratz K, Bourne W, Maguire L, Sugar J, Tu E, Djalilian A, Mootha V, McCulley J, Bowman W, Cavanaugh HD, Verity S, Verdier D, Renucci A, Oliva M, Rotkis W, Hardten DR, Fahmy A, Brown M, Reeves S, Davis EA, Lindstrom R, Hauswirth S, Hamilton S, Lee WB, Price F, Price M, Kelly K, Peters F, Shaughnessy M, Steinemann T, Dupps BJ, Meisler DM, Mifflin M, Olson R, Aldave A, Holland G, Mondino BJ, Rosenwasser G, Gorovoy M, Dunn SP, Heidemann DG, Terry M, Shamie N, Rosenfeld SI, Suedekum B, Hwang D, Stone D, Chodosh J, Galentine PG, Bardenstein D, Goddard K, Chin H, Mannis M, Varma R, Borecki I, Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Deloukas P, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Spencer CC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson R, Strange A, Su Z, Vukcevic D, Donnelly P, Langford C, Hunt SE, Edkins S, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Gray E, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, Barroso I, Deloukas P, Mathew CG, Blackwell JM, Brown MA, Corvin A, Spencer CC, Genuth S, Nathan DM, Zinman B, Crofford O, Crandall J, Reid M, Brown-Friday J, Engel S, Sheindlin J, Martinez H, Shamoon H, Engel H, Phillips M, Gubitosi-Klug R, Mayer L, Pendegast S, Zegarra H, Miller D, Singerman L, Smith-Brewer S, Novak M, Quin J, Dahms W, Genuth S, Palmert M, Brillon D, Lackaye ME, Kiss S, Chan R, Reppucci V, Lee T, Heinemann M, Whitehouse F, Kruger D, Jones JK, McLellan M, Carey JD, Angus E, Thomas A, Galprin A, Bergenstal R, Johnson M, Spencer M, Morgan K, Etzwiler D, Kendall D, Aiello LP, Golden E, Jacobson A, Beaser R, Ganda O, Hamdy O, Wolpert H, Sharuk G, Arrigg P, Schlossman D, Rosenzwieg J, Rand L, Nathan DM, Larkin M, Ong M, Godine J, Cagliero E, Lou P, Folino K, Fritz S, Crowell S, Hansen K, Gauthier-Kelly C, Service J, Ziegler G, Luttrell L, Caulder S, Lopes-Virella M, Colwell J, Soule J, Fernandes J, Hermayer K, Kwon S, Brabham M, Blevins A, Parker J, Lee D, Patel N, Pittman C, Lindsey P, Bracey M, Lee K, Nutaitis M, Farr A, Elsing S, Thompson T, Selby J, Lyons T, Yacoub-Wasef S, Szpiech M, Wood D, Mayfield R, Molitch M, Schaefer B, Jampol L, Lyon A, Gill M, Strugula Z, Kaminski L, Mirza R, Simjanoski E, Ryan D, Kolterman O, Lorenzi G, Goldbaum M, Sivitz W, Bayless M, Counts D, Johnsonbaugh S, Hebdon M, Salemi P, Liss R, Donner T, Gordon J, Hemady R, Kowarski A, Ostrowski D, Steidl S, Jones B, Herman WH, Martin CL, Pop-Busui R, Sarma A, Albers J, Feldman E, Kim K, Elner S, Comer G, Gardner T, Hackel R, Prusak R, Goings L, Smith A, Gothrup J, Titus P, Lee J, Brandle M, Prosser L, Greene DA, Stevens MJ, Vine AK, Bantle J, Wimmergren N, Cochrane A, Olsen T, Steuer E, Rath P, Rogness B, Hainsworth D, Goldstein D, Hitt S, Giangiacomo J, Schade DS, Canady JL, Chapin JE, Ketai C LH, Braunstein S, Bourne PA, Schwartz S, Brucker A, Maschak-Carey BJ, Baker L, Orchard T, Silvers N, Ryan C, Songer T, Doft B, Olson S, Bergren RL, Lobes L, Paczan Rath P, Becker D, Rubinstein D, Conrad PW, Yalamanchi S, Drash A, Morrison A, Bernal ML, Vaccaro-Kish J, Malone J, Pavan PR, Grove N, Iyer MN, Burrows AF, Tanaka EA, Gstalder R, Dagogo-Jack S, Wigley C, Ricks H, Kitabchi A, Murphy MB, Moser S, Meyer D, Iannacone A, Chaum E, Yoser S, Bryer-Ash M, Schussler S, Lambeth H, Raskin P, Strowig S, Zinman B, Barnie A, Devenyi R, Mandelcorn M, Brent M, Rogers S, Gordon A, Palmer J, Catton S, Brunzell J, Wessells H, de Boer IH, Hokanson J, Purnell J, Ginsberg J, Kinyoun J, Deeb S, Weiss M, Meekins G, Distad J, Van Ottingham L, Dupre J, Harth J, Nicolle D, Driscoll M, Mahon J, Canny C, May M, Lipps J, Agarwal A, Adkins T, Survant L, Pate RL, Munn GE, Lorenz R, Feman S, White N, Levandoski L, Boniuk I, Grand G, Thomas M, Joseph DD, Blinder K, Shah G, Boniuk, Burgess, Santiago J, Tamborlane W, Gatcomb P, Stoessel K, Taylor K, Goldstein J, Novella S, Mojibian H, Cornfeld D, Lima J, Bluemke D, Turkbey E, van der Geest RJ, Liu C, Malayeri A, Jain A, Miao C, Chahal H, Jarboe R, Maynard J, Gubitosi-Klug R, Quin J, Gaston P, Palmert M, Trail R, Dahms W, Lachin J, Cleary P, Backlund J, Sun W, Braffett B, Klumpp K, Chan K, Diminick L, Rosenberg D, Petty B, Determan A, Kenny D, Rutledge B, Younes N, Dews L, Hawkins M, Cowie C, Fradkin J, Siebert C, Eastman R, Danis R, Gangaputra S, Neill S, Davis M, Hubbard L, Wabers H, Burger M, Dingledine J, Gama V, Sussman R, Steffes M, Bucksa J, Nowicki M, Chavers B, O'Leary D, Polak J, Harrington A, Funk L, Crow R, Gloeb B, Thomas S, O'Donnell C, Soliman E, Zhang ZM, Prineas R, Campbell C, Ryan C, Sandstrom D, Williams T, Geckle M, Cupelli E, Thoma F, Burzuk B, Woodfill T, Low P, Sommer C, Nickander K, Budoff M, Detrano R, Wong N, Fox M, Kim L, Oudiz R, Weir G, Espeland M, Manolio T, Rand L, Singer D, Stern M, Boulton AE, Clark C, D'Agostino R, Lopes-Virella M, Garvey WT, Lyons TJ, Jenkins A, Virella G, Jaffa A, Carter R, Lackland D, Brabham M, McGee D, Zheng D, Mayfield RK, Boright A, Bull S, Sun L, Scherer S, Zinman B, Natarajan R, Miao F, Zhang L, Chen Z, Nathan DM./titolo:Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error/doi:10.1016%2Fj.ajhg.2013.06.016/rivista:American journal of human genetics (Online)/anno:2013/pagina_da:264/pagina_a:277/intervallo_pagine:264–277/volume:93
American Journal of Human Genetics, 93(2), 264-277
Am. J. Hum. Genet. 93, 264-277 (2013)
American Journal of Human Genetics, 93, 264-277. Cell Press
American Journal of Human Genetics
American journal of human genetics, 93(2), 264-277. Cell Press

مصطلحات موضوعية: Adult, Male, Refractive error, Adolescent, Gene Expression, Locus (genetics), Genome-wide association study, Biology, Ocular Axial Length, Polymorphism, Single Nucleotide, White People, Article, 03 medical and health sciences, 0302 clinical medicine, Asian People, SDG 3 - Good Health and Well-being, medicine, Genetics, Humans, GWAS, Genetic Predisposition to Disease, Genetics(clinical), RSPO1, Eye Proteins, Gene, Genetics (clinical), 030304 developmental biology, Genetic association, Aged, 0303 health sciences, ta1184, Heritability, Middle Aged, ta3121, medicine.disease, Refractive Errors, Axial Length, Eye, Genetic Loci, 030221 ophthalmology & optometry, Eye disorder, Female, Genome-Wide Association Study, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a398895c52d8145ccf1acbe1957292
https://pure.eur.nl/en/publications/1289e535-2c5a-49a4-b46c-c9ff6a6f76b9

المؤلفون: Nicholas G. Martin, René Höhn, Nagahisa Yoshimura, Jonathan H. Lass, Ilkka Seppälä, Masahiro Miyake, Kay-Tee Khaw, Pirro G. Hysi, Rhys Fogarty, Yi Lu, Zoran Vatavuk, Cécile Delcourt, Andrew D. Paterson, John P. Kemp, Jeremy A. Guggenheim, Jaakko Kaprio, Robert P. Igo, James F. Wilson, Stuart MacGregor, Anthony P Khawaja, Beate St Pourcain, Margaret M. DeAngelis, Jing Hua Zhao, Cornelia M. van Duijn, Olavi Pärssinen, Terho Lehtimäki, Roger W. Beuerman, Leslie J. Raffel, Eranga N. Vithana, Caroline Hayward, Cathy Williams, Thomas Meitinger, Lei Zhou, Candice E H Ho, Ozren Polasek, Hoi Suen Wong, Jie Jin Wang, Nicholas J. Timpson, Norbert Pfeiffer, Toomas Haller, Akira Meguro, Wei Chen, Ching-Yu Cheng, Vishal Jhanji, Johannes R. Vingerling, Mika Kähönen, Puya Gharahkhani, Sheng Feng, Nobuhisa Mizuki, Maurice Yap, Katie M Williams, Vincent Tan, Paul Mitchell, Taina Rantanen, Sudha K. Iyengar, Seang-Mei Saw, Christopher J Hammond, Kathryn P. Burdon, Harry Campbell, Sarayut Janmahasatian, Andres Metspalu, Caroline C W Klaver, Jugnoo S Rahi, Kenji Yamashiro, Laura Portas, Céline Bellenguez, Igor Rudan, Robert Luben, Virginie J. M. Verhoeven, Mary Frances Cotch, Paul N. Baird, Qiao Fan, Najaf Amin, David A. Mackey, Jenifer E. Huffman, Emily Y. Chew, Veluchamy A. Barathi, Tien Yin Wong, Ronald Klein, Jeremy Fondran, Mario Pirastu, Alan F. Wright, Jamie E Craig, Brian W Fleck, Paul J. Foster, Alvin L. Young, Alex W. Hewitt, Tin Aung, Maurizio Fossarello, Kari-Matti Mäkelä, Tanja Zeller, Maria Blettner, Xu Wang, Eileen Tai-Hui Boh, Terri L. Young, Mingguang He, Joan E. Bailey Wilson, Olli T. Raitakari, Shea Ping Yip, M. Kamran Ikram, Seyhan Yazar, Albert Hofman, Alireza Mirshahi, Tae Hwi Schwantes-An, Charumathi Sabanayagam, Pancy O. S. Tam, Ginevra Biino, Xiaobo Guo, Angela Döring, Audrey Cougnard-Gregoire, David M. Evans, Xiaohui Li, Christian Gieger, Songhomitra Panda-Jonas, Jost B. Jonas, Jan Willem L Tideman, Maria Schache, Chi Pui Pang, Barbara E.K. Klein, Simona Vaccargiu, Veronique Vitart, Jing Xie, Claire L. Simpson, S. Mohsen Hosseini, Chiea Chuen Khor, Dwight Stambolian, E. Shyong Tai, Xiangtian Zhou, Li Jia Chen, Milly S. Tedja, Margaux A. Morrison, Janina S. Ried, Yik Ying Teo, Konrad Oexle, Robert Wojciechowski, Nicholas J. Wareham, André G. Uitterlinden, Peter K. Joshi, Ya Xing Wang, Jean-François Korobelnik, George McMahon, Vinay Nangia, Elisabeth M. van Leeuwen, Lindsay A. Farrer, Preeti Gupta, Johanna Mazur, Evelin Mihailov, Wan’E. Lim, George Davey Smith, Liang Xu, Rosalynn Grace Siantar, Juho Wedenoja, Cristina Venturini, Fernando Rivadeneira

المساهمون: Clinicum, Department of Public Health, Silmäklinikka, Jaakko Kaprio / Principal Investigator, Institute for Molecular Medicine Finland, Genetic Epidemiology, Consortium for Refractive Error and Myopia (CREAM), Clinical Genetics, Erasmus MC other, Epidemiology, Internal Medicine, Ophthalmology, Obstetrics & Gynecology

المصدر: Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Höhn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimäki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K M, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, Mcmahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-an, T, Igo, R P, Mirshahi, A, Cougnard-gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kähönen, M, Seppala, I, Zeller, T, Meitinger, T, Ried, J S, Gieger, C, Portas, L, Van Leeuwen, E M, Amin, N, Uitterlinden, A G, Rivadeneira, F, Hofman, A, Vingerling, J R, Wang, Y X, Wang, X, Tai-hui Boh, E, Ikram, M K, Sabanayagam, C, Gupta, P, Tan, V, Zhou, L, Ho, C E H, Lim, W, Beuerman, R W, Siantar, R, Tai, E, Vithana, E, Mihailov, E, Khor, C, Hayward, C, Luben, R N, Foster, P J, Klein, B E K, Klein, R, Wong, H, Mitchell, P, Metspalu, A, Aung, T, Young, T L, He, M, Pärssinen, O, Van Duijn, C M, Jin Wang, J, Williams, C, Jonas, J B, Teo, Y, Mackey, D A, Oexle, K, Yoshimura, N, Paterson, A D, Pfeiffer, N, Wong, T, Baird, P N, Stambolian, D, Wilson, J E B, Cheng, C, Hammond, C J, Klaver, C C W, Saw, S, Rahi, J S, Korobelnik, J, Kemp, J P, Timpson, N J, Smith, G D, Craig, J E, Burdon, K P, Fogarty, R D, Iyengar, S K, Chew, E, Janmahasatian, S, Martin, N G, Macgregor, S, Xu, L, Schache, M, Nangia, V, Panda-jonas, S, Wright, A F, Fondran, J R, Lass, J H, Feng, S, Zhao, J H, Khaw, K, Wareham, N J, Rantanen, T, Kaprio, J, Pang, C P, Chen, L J, Tam, P O, Jhanji, V, Young, A L, Döring, A, Raffel, L J, Cotch, M, Li, X, Yip, S P, Yap, M K H, Biino, G, Vaccargiu, S, Fossarello, M, Fleck, B, Yazar, S, Tideman, J W L, Tedja, M, Deangelis, M M, Morrison, M, Farrer, L, Zhou, X, Chen, W, Mizuki, N, Meguro, A & Mäkelä, K M 2016, ' Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, pp. 11008 . https://doi.org/10.1038/ncomms11008
Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Hohn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimaki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K M, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, McMahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-An, T H, Igo, R P, Mirshahi, A, Cougnard-Gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kahonen, M, Seppala, I, Zeller, T, Meitinger, T, Ried, J S, Gieger, C, Portas, L, Van Leeuwen, E M, Amin, N, Uitterlinden, A G, Rivadeneira, F, Hofman, A, Vingerling, J R, Wang, Y X, Wang, X, Tai-Hui Boh, E, Ikram, M K, Sabanayagam, C, Gupta, P, Tan, V, Zhou, L, Ho, C E H, Lim, WE, Beuerman, R W, Siantar, R, Tai, E S, Vithana, E, Mihailov, E, Khor, C C, Hayward, C, Luben, R N, Foster, P J, Klein, B E K, Klein, R, Wong, H S, Mitchell, P, Metspalu, A, Aung, T, Young, T L, He, M, Parssinen, O, Van Duijn, C M, Jin Wang, J, Williams, C, Jonas, J B, Teo, Y Y, MacKey, D A, Oexle, K, Yoshimura, N, Paterson, A D, Pfeiffer, N, Wong, T Y, Baird, P N, Stambolian, D, Wilson, J E B, Cheng, C-Y, Hammond, C J, Klaver, C C W, Saw, S M, Rahi, J S, Korobelnik, J F, Kemp, J P, Timpson, N J, Smith, G D, Craig, J E, Burdon, K P, Fogarty, R D, Iyengar, S K, Chew, E, Janmahasatian, S, Martin, N G, MacGregor, S, Xu, L, Schache, M, Nangia, V, Panda-Jonas, S, Wright, A F, Fondran, J R, Lass, J H, Feng, S, Zhao, J H, Khaw, K T, Wareham, N J, Rantanen, T, Kaprio, J, Pang, C P, Chen, L J, Tam, P O, Jhanji, V, Young, A L, Doring, A, Raffel, L J, Cotch, M F, Li, X, Yip, S P, Yap, M K H, Biino, G, Vaccargiu, S, Fossarello, M, Fleck, B, Yazar, S, Tideman, J W L, Tedja, M, Deangelis, M M, Morrison, M, Farrer, L, Zhou, X, Chen, W, Mizuki, N, Meguro, A & Makela, K M 2016, ' Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, 11008 . https://doi.org/10.1038/ncomms11008
Nature Communications, 7, 11008
Fan, Q, Verhoeven, V J M, Wojciechowski, R, Barathi, V A, Hysi, P G, Guggenheim, J A, Höhn, R, Vitart, V, Khawaja, A P, Yamashiro, K, Hosseini, S M, Lehtimäki, T, Lu, Y, Haller, T, Xie, J, Delcourt, C, Pirastu, M, Wedenoja, J, Gharahkhani, P, Venturini, C, Miyake, M, Hewitt, A W, Guo, X, Mazur, J, Huffman, J E, Williams, K, Polasek, O, Campbell, H, Rudan, I, Vatavuk, Z, Wilson, J F, Joshi, P K, McMahon, G, St Pourcain, B, Evans, D M, Simpson, C L, Schwantes-An, T-H, Igo, R P, Mirshahi, A, Cougnard-Gregoire, A, Bellenguez, C, Blettner, M, Raitakari, O, Kähönen, M, Seppala, I, Zeller, T, Meitinger, T, Zhou, L, Mitchell, P, Hammond, C J 2016, ' Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error ', Nature Communications, vol. 7, 11008 . https://doi.org/10.1038/ncomms11008
Nature Communications
Nature Communications, 7, pp. 11008
Nat. Commun. 7:11008 (2016)
Fan, Qiao; Verhoeven, Virginie J M; Wojciechowski, Robert; Barathi, Veluchamy A; Hysi, Pirro G; Guggenheim, Jeremy A; Höhn, René; Vitart, Veronique; Khawaja, Anthony P; Yamashiro, Kenji; Hosseini, S Mohsen; Lehtimäki, Terho; Lu, Yi; Haller, Toomas; Xie, Jing; Delcourt, Cécile; Pirastu, Mario; Wedenoja, Juho; Gharahkhani, Puya; Venturini, Cristina; ... (2016). Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature communications, 7(11008), p. 11008. Nature Publishing Group 10.1038/ncomms11008 <http://dx.doi.org/10.1038/ncomms11008>
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, 7. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Refractive error, genetic structures, General Physics and Astronomy, Genome-wide association study, VARIANTS, refractive error, gene, EYE, Bioinformatics, INCIDENT MYOPIA, Genome-wide association studies, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], 0302 clinical medicine, Polymorphism (computer science), 10. No inequality, POPULATION, education.field_of_study, Multidisciplinary, ACTIVATED PROTEIN-KINASE, ta3142, single-nucleotide polymorphism, RETINAL-PIGMENT EPITHELIUM, OUTDOOR ACTIVITY, 3142 Public health care science, environmental and occupational health, 3. Good health, Refractive errors, Meta-analysis, loci, Educational Status, Science, Population, 610 Medicine & health, Environment, Biology, ta3111, Polymorphism, Single Nucleotide, Article, White People, General Biochemistry, Genetics and Molecular Biology, Education, 03 medical and health sciences, Asian People, SDG 3 - Good Health and Well-being, Genetic variation, medicine, Humans, SNP, Genetic Predisposition to Disease, myopia, 3125 Otorhinolaryngology, ophthalmology, education, RECEPTOR, Gene Expression Profiling, ta1184, General Chemistry, Heritability, medicine.disease, eye diseases, ta3125, TIME OUTDOORS, 030104 developmental biology, Genetic Loci, Evolutionary biology, RISK-FACTORS, 030221 ophthalmology & optometry, RE, sense organs, 3111 Biomedicine, Genome-Wide Association Study

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https://doi.org/10.1038/ncomms11008

المؤلفون: Francisca A. de Leeuw, Jenny van Dongen, Wiesje M. van der Flier, Leonie Weinhold, Andres Metspalu, Toomas Haller, Catharina E. M. van Beijsterveldt, Mika Kivimäki, Sven J. van der Lee, Martin J. Shipley, Michael Wagner, Johannes Hertel, Aswin Verhoeven, Cornelia M. van Duijn, Krista Fischer, Robert E. Gertzen, Kathrin Budde, Nele Friedrich, Qiong Yang, P. Eline Slagboom, Sudha Seshadri, Maik Pietzner, Vincent Chouraki, Jussi Hernesniemi, Alexander Teumer, Charlotte E. Teunissen, Sarah Egert, Ayse Demirkan, M. Arfan Ikram, Wolfgang Maier, Shuo Li, Philip Scheltens, Juho Tynkkynen, Gonneke Willemsen, Ko Willems van Dijk, Carel F.W. Peeters, René Pool, Dorret I. Boomsma, Veikko Salomaa, Holger Wagner, Najaf Amin, Thomas Hankemeier, Archana Singh-Manoux, Ramachandran S. Vasan, Hans Joergen Grabe, Markus Perola, Debora Melo van Lent, Alfredo Ramirez

المساهمون: Epidemiology, Radiology & Nuclear Medicine, Biological Psychology, APH - Personalized Medicine, APH - Health Behaviors & Chronic Diseases, APH - Mental Health, APH - Methodology, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Amsterdam Neuroscience - Neurodegeneration, Neurology, Laboratory Medicine, Division 6, Epidemiology and Data Science, Institute for Molecular Medicine Finland, University of Helsinki

المصدر: van der Lee, S J, Teunissen, C E, Pool, R, Shipley, M J, Teumer, A, Chouraki, V, Melo van Lent, D, Tynkkynen, J, Fischer, K, Hernesniemi, J, Haller, T, Singh-Manoux, A, Verhoeven, A, Willemsen, G, de Leeuw, F A, Wagner, H, van Dongen, J, Hertel, J, Budde, K, Willems van Dijk, K, Weinhold, L, Ikram, M A, Pietzner, M, Perola, M, Wagner, M, Friedrich, N, Slagboom, P E, Scheltens, P, Yang, Q, Gertzen, R E, Egert, S, Li, S, Hankemeier, T, van Beijsterveldt, C E M, Vasan, R S, Maier, W, Peeters, C F W, Jörgen Grabe, H, Ramirez, A, Seshadri, S, Metspalu, A, Kivimäki, M, Salomaa, V, Demirkan, A, Boomsma, D I, van der Flier, W M, Amin, N & van Duijn, C M 2018, ' Circulating metabolites and general cognitive ability and dementia : Evidence from 11 cohort studies ', Alzheimers & Dementia, vol. 14, no. 6, pp. 707-722 . https://doi.org/10.1016/j.jalz.2017.11.012
Alzheimer's & Dementia
Alzheimers & Dementia
Alzheimers & Dementia, 14(6), 707-722. Elsevier Inc.
van der Lee, S J, Teunissen, C E, Pool, R, Shipley, M J, Teumer, A, Chouraki, V, Melo van Lent, D, Tynkkynen, J, Fischer, K, Hernesniemi, J, Haller, T, Singh-Manoux, A, Verhoeven, A, Willemsen, G, de Leeuw, F A, Wagner, H, van Dongen, J, Hertel, J, Budde, K, Willems van Dijk, K, Weinhold, L, Ikram, M A, Pietzner, M, Perola, M, Wagner, M, Friedrich, N, Slagboom, P E, Scheltens, P, Yang, Q, Gertzen, R E, Egert, S, Li, S, Hankemeier, T, van Beijsterveldt, C E M, Vasan, R S, Maier, W, Peeters, C F W, Jörgen Grabe, H, Ramirez, A, Seshadri, S, Metspalu, A, Kivimäki, M, Salomaa, V, Demirkan, A, Boomsma, D I, van der Flier, W M, Amin, N & van Duijn, C M 2018, ' Circulating metabolites and general cognitive ability and dementia : Evidence from 11 cohort studies ', Alzheimer's and Dementia, vol. 14, no. 6, pp. 707-722 . https://doi.org/10.1016/j.jalz.2017.11.012
Alzheimer's and Dementia
Alzheimer's and Dementia, 14(6), 707-722
Alzheimer's and Dementia, 14(6), 707-722. Elsevier
Alzheimer's and dementia 14(6), 707-722 (2018). doi:10.1016/j.jalz.2017.11.012

مصطلحات موضوعية: 0301 basic medicine, Oncology, Apolipoprotein E, Netherlands Twin Register (NTR), Male, Epidemiology, Genome-wide association study, Disease, LOTHIAN BIRTH COHORT, Lifestyle factors, 3124 Neurology and psychiatry, FATTY-ACID-COMPOSITION, Cohort Studies, metabolism [Cognitive Dysfunction], 0302 clinical medicine, Risk Factors, Metabolites, Cognitive decline, Health Policy, Cognition, Alzheimer's disease, Middle Aged, 3. Good health, ALZHEIMERS-DISEASE, Psychiatry and Mental health, Female, Cognitive function, ERASMUS RUCPHEN FAMILY, metabolism [Alzheimer Disease], metabolism [Biomarkers], Cohort study, Adult, medicine.medical_specialty, HDL, General cognitive ability, UNITED-STATES, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, SDG 3 - Good Health and Well-being, Alzheimer Disease, Internal medicine, mental disorders, medicine, Dementia, Metabolomics, Humans, Cognitive Dysfunction, ddc:610, metabolism [Dementia], GENOME-WIDE ASSOCIATION, SERUM-CHOLESTEROL, Life Style, Aged, BLOOD-BRAIN-BARRIER, business.industry, 3112 Neurosciences, Reproducibility of Results, ROTTERDAM, medicine.disease, NMR, 030104 developmental biology, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery, Biomarkers, Lipoprotein

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