المؤلفون: Li M; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Teater MR; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Hong JY; Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Cornell University, Ithaca, New York., Park NR; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey., Duy C; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Shen H; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Wang L; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Chen Z; Division of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, New York., Cerchietti L; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York., Davidson SM; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey., Lin H; Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Cornell University, Ithaca, New York. amm2014@med.cornell.edu hl379@cornell.edu., Melnick AM; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York. amm2014@med.cornell.edu hl379@cornell.edu.

المصدر: Blood cancer discovery [Blood Cancer Discov] 2022 Jan; Vol. 3 (1), pp. 50-65. Date of Electronic Publication: 2021 Nov 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Lymphoma, Large B-Cell, Diffuse*/genetics , Sirtuin 3*/genetics, Activating Transcription Factor 4/genetics ; Amino Acids/metabolism ; Citric Acid Cycle ; Glutamine/metabolism ; Humans ; Mitochondria/metabolism

المؤلفون: Li M; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Chiang YL; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA., Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Teater MR; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Hong JY; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA., Shen H; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Wang L; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Hu J; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA., Jing H; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA., Chen Z; Division of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, NY 10021, USA., Jain N; Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA., Duy C; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Mistry SJ; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Cerchietti L; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Cross JR; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA., Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Green MR; Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA., Lin H; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA; Howard Hughes Medical Institute; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: hl379@cornell.edu., Melnick AM; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: amm2014@med.cornell.edu.

المصدر: Cancer cell [Cancer Cell] 2019 Jun 10; Vol. 35 (6), pp. 916-931.e9.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation/*drug effects , Energy Metabolism/*drug effects , Lymphoma, Large B-Cell, Diffuse/*enzymology , Sirtuin 3/*metabolism, Acetyl Coenzyme A/metabolism ; Animals ; Antineoplastic Agents/pharmacology ; Autophagic Cell Death/drug effects ; Citric Acid Cycle/drug effects ; Female ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Glutamine/metabolism ; HEK293 Cells ; Histone Deacetylase Inhibitors/pharmacology ; Humans ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/pathology ; MCF-7 Cells ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Molecular Targeted Therapy ; Signal Transduction ; Sirtuin 3/antagonists & inhibitors ; Sirtuin 3/deficiency ; Sirtuin 3/genetics ; Xenograft Model Antitumor Assays