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1دورية أكاديمية
المؤلفون: Wei Zheng, Xiaoqin Dai, Binyao Xu, Wei Tian, Jianyou Shi
المصدر: Frontiers in Pharmacology, Vol 14 (2023)
مصطلحات موضوعية: FXa, coagulation cascade, small molecule drug design, structure-activity relationship, anticoagulant activity, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2
المؤلفون: Liyun Zhao, Li Liu, Xuanlin Feng, Qi Liang, Jianyou Shi, Lan Bai, Xuan Xiong, Rongsheng Tong
المصدر: Chinese Chemical Letters. 33:1841-1849
مصطلحات موضوعية: DYRK1A, Kinase, Mechanism (biology), Cancer, Tyrosine phosphorylation, General Chemistry, Pharmacology, Biology, medicine.disease, chemistry.chemical_compound, Harmine, chemistry, medicine, Structure–activity relationship, Protein kinase A
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3
المؤلفون: Qi Liang, Maoyu Liu, Jian Li, Rongsheng Tong, Yonghe Hu, Lan Bai, Jianyou Shi
المصدر: European Journal of Medicinal Chemistry. 231:114156
مصطلحات موضوعية: Pharmacology, Structure-Activity Relationship, Stomach Neoplasms, Carcinoma, Organic Chemistry, Drug Discovery, Humans, Antineoplastic Agents, Cyclopentanes, General Medicine, Ubiquitins
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4
المؤلفون: Xiaojiao Luo, Xingkai Du, Feng Li, Li Rong, Yiwen Zhang, Jian Li, Jianyou Shi, Jun He
المصدر: European journal of medicinal chemistry. 203
مصطلحات موضوعية: Cell cycle checkpoint, Antineoplastic Agents, Computational biology, P53 Mutation, 01 natural sciences, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, Animals, Humans, Mitotic catastrophe, Protein Kinase Inhibitors, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, 010405 organic chemistry, Kinase, Chemistry, Organic Chemistry, Cell Cycle, Rational design, General Medicine, Cell cycle, Protein-Tyrosine Kinases, 0104 chemical sciences, Wee1, Cancer cell, biology.protein
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5
المؤلفون: Xiujuan Fu, Jianyou Shi, Yanping Zhou, Rongsheng Tong, Zhongliang Jiang, Lijuan Zhang, Lei Zhong, Jian Li
المصدر: Chemistry & Biodiversity. 16
مصطلحات موضوعية: Male, Stereochemistry, Antineoplastic Agents, Apoptosis, Bioengineering, 01 natural sciences, Biochemistry, Cell Line, Rats, Sprague-Dawley, Small Molecule Libraries, Structure-Activity Relationship, chemistry.chemical_compound, Animals, Humans, Structure–activity relationship, Cytotoxicity, Benzamide, Glycogen synthase, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, Cell Proliferation, Glycogen Synthase Kinase 3 beta, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, General Chemistry, General Medicine, Small molecule, In vitro, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Drug Design, Benzamides, Lactam, biology.protein, Molecular Medicine, Female, Drug Screening Assays, Antitumor
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6
المؤلفون: Jianyou Shi, Jing Zou, Chengchen Zhang, Baowen Qi, Fengqiong Li, Xiaoqiang Guo, Hongjia Zhang, Ting Wang, Jun He, Ling Zhong, Yao-Xin Lin, Rui Li
المصدر: Journal of medicinal chemistry. 62(17)
مصطلحات موضوعية: Cell Survival, In silico, Cell, Mice, Nude, Antineoplastic Agents, Cell Cycle Proteins, Protein Serine-Threonine Kinases, 01 natural sciences, Rats, Sprague-Dawley, 03 medical and health sciences, Mice, Structure-Activity Relationship, In vivo, Proto-Oncogene Proteins, Drug Discovery, medicine, Tumor Cells, Cultured, Animals, Humans, Kinome, Mitosis, Protein Kinase Inhibitors, 030304 developmental biology, Aurora Kinase A, Cell Proliferation, 0303 health sciences, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, Kinase, Tumor Suppressor Proteins, Neoplasms, Experimental, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, Cancer cell, Cancer research, Molecular Medicine, Female, Drug Screening Assays, Antitumor
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7
المؤلفون: Yuxuan, Zhu, Ting, Yuan, Yuan, Zhang, Jianyou, Shi, Lan, Bai, Xingmei, Duan, Rongsheng, Tong, Lei, Zhong
المصدر: Drug Design, Development and Therapy
مصطلحات موضوعية: Esophageal Neoplasms, Molecular Conformation, Angiogenesis Inhibitors, Antineoplastic Agents, Apoptosis, Mice, SCID, esophageal squamous cell cancer, Mice, Structure-Activity Relationship, angiogenesis, Mice, Inbred NOD, Cell Line, Tumor, Animals, Humans, AR-42, neoplasms, Zebrafish, Cell Proliferation, Original Research, Dose-Response Relationship, Drug, Neovascularization, Pathologic, Neoplasms, Experimental, Phenylbutyrates, digestive system diseases, Histone Deacetylase Inhibitors, histone deacetylase, Esophageal Squamous Cell Carcinoma, Drug Screening Assays, Antitumor
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8
المؤلفون: Ting Yuan, Jianyou Shi, Lei Zhong, Jiying Yu, Wenjuan Dong, Baowen Qi, Lan Bai, Zhongliang Jiang, Rongsheng Tong
المصدر: European journal of medicinal chemistry. 178
مصطلحات موضوعية: Antineoplastic Agents, Drug resistance, Gene mutation, 01 natural sciences, Receptor tyrosine kinase, Pathogenesis, 03 medical and health sciences, Structure-Activity Relationship, fluids and secretions, hemic and lymphatic diseases, Drug Discovery, Animals, Humans, neoplasms, Protein Kinase Inhibitors, 030304 developmental biology, Cell Proliferation, Pharmacology, 0303 health sciences, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Myeloid leukemia, hemic and immune systems, General Medicine, 0104 chemical sciences, Haematopoiesis, Leukemia, Myeloid, Acute, fms-Like Tyrosine Kinase 3, Drug Resistance, Neoplasm, embryonic structures, biology.protein, Cancer research, Stem cell, Drug Screening Assays, Antitumor, Tyrosine kinase
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9
المؤلفون: Yujuan Chen, Jianyou Shi, Hairun Pei, Hengming Ke, Meng Zhang, Ting Yao, Huanchen Wang, Yousheng Wang, Yiyou Huang
المصدر: Biochemistry
مصطلحات موضوعية: chemistry.chemical_classification, biology, Active site, Substrate (chemistry), biology.organism_classification, Crystallography, X-Ray, Biochemistry, Cyclic Nucleotide Phosphodiesterases, Type 2, Corpus albicans, Yeast, Article, Protein Structure, Secondary, Fungal Proteins, Structure-Activity Relationship, Enzyme, chemistry, Protein Domains, Hydrolase, Candida albicans, biology.protein, Biophysics, Phosphodiesterase 2
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad53167cbcdce70c51fdeccea320f56c
https://europepmc.org/articles/PMC9364965/ -
10
المؤلفون: Rongsheng Tong, Xiaoqiang Guo, Xingxing Li, Xinyu Liu, Jianyou Shi, Baowen Qi, Zhongliang Jiang, Xia He, Ling Zhu, Xingmei Duan, Jing Liao, Zhuyu Xu, Shan Chen
المصدر: European Journal of Medicinal Chemistry. 186:111852
مصطلحات موضوعية: medicine.medical_specialty, Disease, 01 natural sciences, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Renin–angiotensin system, medicine, Animals, Humans, Enzyme Inhibitors, Intensive care medicine, 030304 developmental biology, Heart Failure, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, High mortality, General Medicine, medicine.disease, Small molecule, 0104 chemical sciences, Clinical research, Heart failure