المؤلفون: Prast-Nielsen S; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Dexheimer TS, Schultz L, Stafford WC, Cheng Q, Xu J, Jadhav A, Arnér ES, Simeonov A

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2011 May 01; Vol. 50 (9), pp. 1114-23. Date of Electronic Publication: 2011 Jan 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Screening Assays*, Acetophenones/*pharmacology , Benzopyrans/*pharmacology , Protoporphyrins/*pharmacology , Recombinant Proteins/*metabolism , Thioredoxin Reductase 1/*metabolism, Binding, Competitive ; Enzyme Inhibitors/pharmacology ; Escherichia coli ; Fluorescence ; Hemin/pharmacology ; Humans ; Kinetics ; Lung Neoplasms/drug therapy ; Molecular Targeted Therapy ; NADP/metabolism ; Oxidation-Reduction ; Recombinant Proteins/antagonists & inhibitors ; Recombinant Proteins/genetics ; Small Molecule Libraries/analysis ; Sodium Selenite/metabolism ; Thioredoxin Reductase 1/antagonists & inhibitors ; Thioredoxin Reductase 1/genetics ; Tumor Cells, Cultured

المؤلفون: Eriksson SE; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Prast-Nielsen S, Flaberg E, Szekely L, Arnér ES

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2009 Dec 01; Vol. 47 (11), pp. 1661-71. Date of Electronic Publication: 2009 Sep 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*drug therapy , Lung Neoplasms/*drug therapy , Thioredoxin Reductase 1/*metabolism, Adenocarcinoma/enzymology ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Apoptosis/drug effects ; Apoptosis/genetics ; Auranofin/pharmacology ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Growth Processes/drug effects ; Cell Growth Processes/genetics ; Cell Line, Tumor ; Cisplatin/pharmacology ; Dinitrochlorobenzene/pharmacology ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Humans ; Lung Neoplasms/enzymology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Naphthoquinones/pharmacology ; RNA, Small Interfering/genetics ; Thioredoxin Reductase 1/genetics ; Vitamin K 3/pharmacology