المؤلفون: Buchan AM; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7LE, UK; Oxford Medical School, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Electronic address: alastair.buchan@medsci.ox.ac.uk., Karbalai HG; Oxford Medical School, University of Oxford, Oxford, UK., Sutherland BA; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

المصدر: Lancet (London, England) [Lancet] 2015 Aug 15; Vol. 386 (9994), pp. 654.

نوع المنشور: Letter

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE

مواضيع طبية MeSH: Fibrinolytic Agents/*therapeutic use , Stroke/*therapy , Tissue Plasminogen Activator/*therapeutic use, Combined Modality Therapy ; Early Diagnosis ; Endovascular Procedures ; Humans ; Stents ; Stroke/diagnosis ; Tomography, X-Ray Computed

المؤلفون: Sutherland BA; Acute Stroke Programme, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Buchan AM

المصدر: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2013 Nov; Vol. 33 (11), pp. e1-7. Date of Electronic Publication: 2013 Aug 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*drug effects , Cerebrovascular Circulation/*drug effects , Fibrinolytic Agents/*therapeutic use , Infarction, Middle Cerebral Artery/*drug therapy , Tissue Plasminogen Activator/*therapeutic use, Animals ; Arginine/chemistry ; Arginine/pharmacology ; Brain/blood supply ; Brain/pathology ; Cerebral Hemorrhage/prevention & control ; Disease Models, Animal ; Drug Carriers/chemistry ; Drug Carriers/pharmacology ; Fibrinolytic Agents/administration & dosage ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/physiopathology ; Male ; Rats ; Rats, Wistar ; Survival Analysis ; Tissue Plasminogen Activator/administration & dosage

المؤلفون: Balami JS; Acute Stroke Programme, Department of Medicine and Clinical Geratology, Oxford University Hospitals NHS Trust, Oxford, UK., Sutherland BA, Buchan AM

المصدر: CNS & neurological disorders drug targets [CNS Neurol Disord Drug Targets] 2013 Mar; Vol. 12 (2), pp. 155-69.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101269155 Publication Model: Print Cited Medium: Internet ISSN: 1996-3181 (Electronic) Linking ISSN: 18715273 NLM ISO Abbreviation: CNS Neurol Disord Drug Targets Subsets: MEDLINE

مواضيع طبية MeSH: Stroke/*drug therapy , Thrombolytic Therapy/*adverse effects , Tissue Plasminogen Activator/*adverse effects, Animals ; Humans ; Tissue Plasminogen Activator/biosynthesis

المؤلفون: Dzialowski I; Department of Clinical Neurosciences, University of Calgary, Calgary Stroke Program, Canada. imanuel.dzialowski@uniklinikum-dresden.de., Puetz V, Buchan AM, Demchuk AM, Hill MD

مؤلفون مشاركون: Calgary Stroke Program

المصدر: Stroke [Stroke] 2012 Jun; Vol. 43 (6), pp. 1567-71. Date of Electronic Publication: 2012 Apr 10.

نوع المنشور: Clinical Trial; Comparative Study; Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

مواضيع طبية MeSH: Brain Ischemia*/diagnostic imaging , Brain Ischemia*/drug therapy , Stroke*/diagnostic imaging , Stroke*/drug therapy, Contrast Media/*administration & dosage , Fibrinolytic Agents/*administration & dosage , Tissue Plasminogen Activator/*administration & dosage , Tissue Plasminogen Activator/*antagonists & inhibitors, Acute Disease ; Aged ; Aged, 80 and over ; Drug Antagonism ; Female ; Humans ; Male ; Middle Aged ; Radiography

المؤلفون: Shobha N; Calgary Stroke Program, Department of Clinical Neurosciences, Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada., Buchan AM, Hill MD

مؤلفون مشاركون: Canadian Alteplase for Stroke Effectiveness Study (CASES)

المصدر: Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2011; Vol. 31 (3), pp. 223-8. Date of Electronic Publication: 2010 Dec 21.

نوع المنشور: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 9100851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9786 (Electronic) Linking ISSN: 10159770 NLM ISO Abbreviation: Cerebrovasc Dis Subsets: MEDLINE

مواضيع طبية MeSH: Thrombolytic Therapy*/adverse effects , Thrombolytic Therapy*/mortality, Brain Ischemia/*drug therapy , Fibrinolytic Agents/*administration & dosage , Stroke/*drug therapy , Tissue Plasminogen Activator/*administration & dosage, Aged ; Aged, 80 and over ; Brain Ischemia/blood ; Brain Ischemia/complications ; Brain Ischemia/mortality ; Canada ; Chi-Square Distribution ; Drug Administration Schedule ; Female ; Fibrinolytic Agents/adverse effects ; Humans ; Infusions, Intravenous ; Intracranial Hemorrhages/chemically induced ; Male ; Middle Aged ; Patient Selection ; Prospective Studies ; Registries ; Regression Analysis ; Risk Assessment ; Risk Factors ; Stroke/blood ; Stroke/etiology ; Stroke/mortality ; Time Factors ; Tissue Plasminogen Activator/adverse effects ; Treatment Outcome

المؤلفون: Harston GW; Nuffield Department of Clinical Medicine, Acute Stroke Programme, University of Oxford, Oxford, UK., Sutherland BA, Kennedy J, Buchan AM

المصدر: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2010 Nov; Vol. 30 (11), pp. 1804-16. Date of Electronic Publication: 2010 Aug 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

مواضيع طبية MeSH: Arginine/*adverse effects , Brain Ischemia/*drug therapy , Fibrinolytic Agents/*adverse effects , Neurotoxicity Syndromes/*etiology , Tissue Plasminogen Activator/*adverse effects, Animals ; Arginine/pharmacology ; Brain/metabolism ; Brain Ischemia/etiology ; Brain Ischemia/pathology ; Brain Ischemia/physiopathology ; Cerebrovascular Circulation/drug effects ; Drug Interactions ; Drug Stability ; Fibrinolytic Agents/therapeutic use ; Humans ; Isoenzymes/metabolism ; Neurotoxins/metabolism ; Nitric Oxide/chemical synthesis ; Nitric Oxide Synthase/metabolism ; Receptors, LDL/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Recombinant Proteins/adverse effects ; Severity of Illness Index ; Tissue Plasminogen Activator/drug effects ; Tissue Plasminogen Activator/therapeutic use

المؤلفون: Mateen FJ, Buchan AM, Hill MD

مؤلفون مشاركون: CASES Investigators

المصدر: Stroke [Stroke] 2010 Aug; Vol. 41 (8), pp. 1833-5. Date of Electronic Publication: 2010 Jun 24.

نوع المنشور: Comparative Study; Letter

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

مواضيع طبية MeSH: Brain Ischemia/*drug therapy , Stroke/*drug therapy , Tissue Plasminogen Activator/*therapeutic use, Age Factors ; Aged, 80 and over ; Canada ; Female ; Fibrinolytic Agents/therapeutic use ; Humans ; Male ; Registries ; Thrombolytic Therapy/methods ; Treatment Outcome

المؤلفون: Poppe AY; Calgary Stroke Program, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada., Buchan AM, Hill MD

المصدر: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques [Can J Neurol Sci] 2009 Mar; Vol. 36 (2), pp. 161-7.

نوع المنشور: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: published by Cambridge University Press for the Canadian Neurological Sciences Federation Country of Publication: England NLM ID: 0415227 Publication Model: Print Cited Medium: Print ISSN: 0317-1671 (Print) Linking ISSN: 03171671 NLM ISO Abbreviation: Can J Neurol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Fibrinolytic Agents/*administration & dosage , Stroke/*drug therapy , Tissue Plasminogen Activator/*administration & dosage, Adult ; Aged ; Comorbidity ; Female ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Stroke/epidemiology ; Thrombolytic Therapy

المؤلفون: Steffenhagen N; Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alta., Canada. nikolai.steffenhagen@Medizin.Uni-Leipzig.de, Hill MD, Poppe AY, Buchan AM, Coutts SB

المصدر: Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2009; Vol. 28 (2), pp. 201-2. Date of Electronic Publication: 2009 Jun 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 9100851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9786 (Electronic) Linking ISSN: 10159770 NLM ISO Abbreviation: Cerebrovasc Dis Subsets: MEDLINE

مواضيع طبية MeSH: National Institutes of Health (U.S.)* , Patient Selection* , Thrombolytic Therapy*/adverse effects, Fibrinolytic Agents/*administration & dosage , Stroke/*drug therapy , Tissue Plasminogen Activator/*administration & dosage, Aged ; Aged, 80 and over ; Female ; Fibrinolytic Agents/adverse effects ; Humans ; Intracranial Hemorrhages/etiology ; Male ; Middle Aged ; Odds Ratio ; Registries ; Risk Assessment ; Severity of Illness Index ; Stroke/diagnosis ; Tissue Plasminogen Activator/adverse effects ; Treatment Outcome ; United States

المؤلفون: Kennedy J; Nuffield Department of Clinical Medicine, Oxford Acute Stroke Programme, John Radcliffe Hospital, Oxford, UK., Buchan AM

المصدر: International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2007 Feb; Vol. 2 (1), pp. 45-6.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101274068 Publication Model: Print Cited Medium: Internet ISSN: 1747-4949 (Electronic) Linking ISSN: 17474930 NLM ISO Abbreviation: Int J Stroke Subsets: MEDLINE

مواضيع طبية MeSH: Fibrinolytic Agents/*administration & dosage , Stroke/*drug therapy , Tissue Plasminogen Activator/*administration & dosage, Clinical Trials as Topic ; Humans ; Infusions, Intra-Arterial ; Injections, Intravenous