المؤلفون: Ryu D; Department of Pharmacy and BK21FOUR Advanced Program for SmartPharma Leaders, Graduate School of the Catholic University of Korea, Bucheon-si, Gyeonggi-do, 14662, Republic of Korea., Lee JH; Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon-si, Gyeonggi-do, 14662, Republic of Korea., Kwak MK; Department of Pharmacy and BK21FOUR Advanced Program for SmartPharma Leaders, Graduate School of the Catholic University of Korea, Bucheon-si, Gyeonggi-do, 14662, Republic of Korea. mkwak@catholic.ac.kr.; Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Bucheon-si, Gyeonggi-do, 14662, Republic of Korea. mkwak@catholic.ac.kr.; College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si, Gyeonggi-do, 14662, Republic of Korea. mkwak@catholic.ac.kr.

المصدر: Archives of pharmacal research [Arch Pharm Res] 2020 Dec; Vol. 43 (12), pp. 1297-1310. Date of Electronic Publication: 2020 Nov 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE

مواضيع طبية MeSH: Cell Movement/*drug effects , Lung Neoplasms/*enzymology , NADPH Oxidase 4/*metabolism , NF-E2-Related Factor 2/*metabolism , Reactive Oxygen Species/*metabolism , Transforming Growth Factor beta1/*pharmacology, A549 Cells ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; NADPH Oxidase 4/genetics ; NF-E2-Related Factor 2/genetics ; Neoplasm Invasiveness ; Signal Transduction

المؤلفون: Song MK; Department of Pharmacy and BK21PLUS Team for Creative Leader Program for Pharmacomics-based Future Pharmacy, Graduate School of The Catholic University of Korea, 43 Jibong-ro, Bucheon, Gyeonggi-do, 14662, Republic of Korea., Lee JH; Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Republic of Korea., Ryoo IG; Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Republic of Korea., Lee SH; Department of Pharmacy and BK21PLUS Team for Creative Leader Program for Pharmacomics-based Future Pharmacy, Graduate School of The Catholic University of Korea, 43 Jibong-ro, Bucheon, Gyeonggi-do, 14662, Republic of Korea., Ku SK; College of Korean Medicine, Daegu Haany University, Gyeongsan, Gyeonsangbuk-do, 712-715, Republic of Korea., Kwak MK; Department of Pharmacy and BK21PLUS Team for Creative Leader Program for Pharmacomics-based Future Pharmacy, Graduate School of The Catholic University of Korea, 43 Jibong-ro, Bucheon, Gyeonggi-do, 14662, Republic of Korea; Integrated Research Institute for Pharmaceutical Sciences, The Catholic University of Korea, Republic of Korea; College of Pharmacy, The Catholic University of Korea, Republic of Korea. Electronic address: mkwak@catholic.ac.kr.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2019 Jul; Vol. 138, pp. 33-42. Date of Electronic Publication: 2019 May 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Kelch-Like ECH-Associated Protein 1/*genetics , Kidney Diseases/*drug therapy , NF-E2-Related Factor 2/*genetics , Oleanolic Acid/*analogs & derivatives , Smad7 Protein/*genetics , Transforming Growth Factor beta1/*genetics, Animals ; Aristolochic Acids/administration & dosage ; Cell Line ; Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Fibrosis ; Gene Expression Regulation ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Kelch-Like ECH-Associated Protein 1/deficiency ; Kidney Diseases/chemically induced ; Kidney Diseases/genetics ; Kidney Diseases/pathology ; Male ; Mesangial Cells/drug effects ; Mesangial Cells/metabolism ; Mesangial Cells/pathology ; Mice ; Mice, Inbred C57BL ; NF-E2-Related Factor 2/metabolism ; Oleanolic Acid/pharmacology ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Smad7 Protein/metabolism ; Transforming Growth Factor beta1/metabolism ; Ubiquitin-Protein Ligases/antagonists & inhibitors ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

المؤلفون: Kwak MK; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Yang KM; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Park J; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Lee S; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Park Y; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biomedical Science, College of Life Science, CHA University, CHA Bio Complex, Bundang-ku, Seongnam City, 463-400 Kyunggi-do, Republic of Korea., Hong E; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea., Sun EJ; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., An H; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea., Park S; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Pang K; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biomedical Science, College of Life Science, CHA University, CHA Bio Complex, Bundang-ku, Seongnam City, 463-400 Kyunggi-do, Republic of Korea., Lee J; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biomedical Science, College of Life Science, CHA University, CHA Bio Complex, Bundang-ku, Seongnam City, 463-400 Kyunggi-do, Republic of Korea., Kang JM; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Kim P; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Biomedical Science, College of Life Science, CHA University, CHA Bio Complex, Bundang-ku, Seongnam City, 463-400 Kyunggi-do, Republic of Korea., Ooshima A; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea., Kim SJ; Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea; Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Kyunggi-do 16229, Republic of Korea. Electronic address: jasonsjkim@snu.ac.kr.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2017 Dec 16; Vol. 494 (3-4), pp. 706-713. Date of Electronic Publication: 2017 Oct 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation/*drug effects , Flavonoids/*administration & dosage , Neoplasms/*drug therapy , Neoplasms/*metabolism , Smad3 Protein/*metabolism , Transforming Growth Factor beta1/*metabolism, Antineoplastic Agents/administration & dosage ; Apoptosis/drug effects ; Binding Sites ; Cell Line, Tumor ; Humans ; Neoplasms/pathology ; Phosphorylation/drug effects ; Protein Binding ; Threonine/metabolism ; Treatment Outcome

المؤلفون: Ryoo IG; College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon, Gyeonggi-do, 420-743, Republic of Korea., Shin DH, Kang KS, Kwak MK

المصدر: Archives of pharmacal research [Arch Pharm Res] 2015 Feb; Vol. 38 (2), pp. 272-81. Date of Electronic Publication: 2014 May 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE

مواضيع طبية MeSH: Epithelial Cells/*drug effects , Epithelial-Mesenchymal Transition/*drug effects , Glutathione/*metabolism , Kidney Tubules, Proximal/*drug effects , NF-E2-Related Factor 2/*metabolism , Transforming Growth Factor beta1/*pharmacology, Animals ; Cell Line ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression/drug effects ; Gene Knockdown Techniques ; Kidney Tubules, Proximal/cytology ; Kidney Tubules, Proximal/metabolism ; NF-E2-Related Factor 2/genetics ; Rats ; Recombinant Proteins ; Signal Transduction/drug effects ; Signal Transduction/genetics

المؤلفون: Ryoo IG; College of Pharmacy, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea., Ha H; College of Pharmacy, Ewha Womans University, Seodaemun-gu, Seoul, Republic of Korea., Kwak MK; College of Pharmacy, The Catholic University of Korea, Bucheon, Gyeonggi-do, Republic of Korea.

المصدر: PloS one [PLoS One] 2014 Apr 01; Vol. 9 (4), pp. e93265. Date of Electronic Publication: 2014 Apr 01 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transdifferentiation/*drug effects , Intracellular Signaling Peptides and Proteins/*metabolism , NF-E2-Related Factor 2/*metabolism , Signal Transduction/*drug effects , Transforming Growth Factor beta1/*pharmacology, Cell Transdifferentiation/genetics ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type I, alpha 1 Chain ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition/drug effects ; Epithelial-Mesenchymal Transition/genetics ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression ; Gene Knockdown Techniques ; Glutathione/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Kelch-Like ECH-Associated Protein 1 ; Kidney/cytology ; Kidney/metabolism ; Kidney Tubules/cytology ; Kidney Tubules/metabolism ; NF-E2-Related Factor 2/genetics ; RNA Interference ; Reactive Oxygen Species/metabolism ; Smad Proteins/metabolism

المؤلفون: Choi HK; BK21 Project Team, College of Pharmacy, Chosun University, 375 Seosuk-dong, Dong-gu, Gwangju 501-759, South Korea., Pokharel YR, Lim SC, Han HK, Ryu CS, Kim SK, Kwak MK, Kang KW

المصدر: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2009 Nov 01; Vol. 240 (3), pp. 377-84. Date of Electronic Publication: 2009 Aug 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Liver Cirrhosis/*prevention & control , NF-E2-Related Factor 2/*physiology , Transforming Growth Factor beta1/*metabolism , Ubiquinone/*analogs & derivatives, Actins/biosynthesis ; Animals ; Base Sequence ; Cell Line, Tumor ; DNA Primers ; Liver Cirrhosis/metabolism ; Male ; Mice ; Mice, Inbred ICR ; Rats ; Reverse Transcriptase Polymerase Chain Reaction ; Solubility ; Transforming Growth Factor beta1/biosynthesis ; Ubiquinone/pharmacology