المؤلفون: Kumagai S; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-0045, Japan; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Koyama S; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan. Electronic address: skoyama@east.ncc.go.jp., Itahashi K; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Tanegashima T; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Lin YT; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Togashi Y; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Kamada T; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Irie T; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Okumura G; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Kono H; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Ito D; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Fujii R; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Watanabe S; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Sai A; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Fukuoka S; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Sugiyama E; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Watanabe G; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Owari T; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Nishinakamura H; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Sugiyama D; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan., Maeda Y; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan., Kawazoe A; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan., Yukami H; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan., Chida K; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan., Ohara Y; Pathology and Clinical Laboratories, National Cancer Center Hospital East, Chiba 277-8577, Japan., Yoshida T; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Shinno Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Takeyasu Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Shirasawa M; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Nakama K; Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital East, Chiba 277-8577, Japan., Suzuki J; Department of Thoracic Surgery, National Cancer Center Hospital East, Chiba 277-8577, Japan., Ishii G; Pathology and Clinical Laboratories, National Cancer Center Hospital East, Chiba 277-8577, Japan., Kuwata T; Pathology and Clinical Laboratories, National Cancer Center Hospital East, Chiba 277-8577, Japan., Sakamoto N; Pathology and Clinical Laboratories, National Cancer Center Hospital East, Chiba 277-8577, Japan., Kawazu M; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-0045, Japan., Ueno T; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-0045, Japan., Mori T; Department of Pathology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Yamazaki N; Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital East, Chiba 277-8577, Japan., Yatabe Y; Department of Pathology, National Cancer Center Hospital, Tokyo 104-0045, Japan., Kinoshita T; Department of Gastric Surgery, National Cancer Center Hospital East, Chiba 277-8577, Japan., Doi T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan., Shitara K; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba 277-8577, Japan., Mano H; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo 104-0045, Japan., Nishikawa H; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo 104-0045/Chiba 277-8577, Japan; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan. Electronic address: hnishika@ncc.go.jp.

المصدر: Cancer cell [Cancer Cell] 2022 Feb 14; Vol. 40 (2), pp. 201-218.e9. Date of Electronic Publication: 2022 Jan 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*/drug effects, Lactic Acid/*metabolism , Programmed Cell Death 1 Receptor/*genetics , T-Lymphocytes, Regulatory/*metabolism , Tumor Microenvironment/*genetics, Animals ; Biomarkers, Tumor ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Cell Line, Tumor ; Disease Models, Animal ; Fluorescent Antibody Technique ; Glycolysis ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Immune Checkpoint Proteins/metabolism ; Immunophenotyping ; Lactic Acid/pharmacology ; Lymphocyte Activation ; Lymphocyte Count ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Mice ; Molecular Targeted Therapy ; Prognosis ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/metabolism ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; Treatment Outcome ; Tumor Microenvironment/drug effects

المؤلفون: Hoshino H; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.; Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Miyoshi T; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Tane K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kojima M; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Sugano M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kuwata T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ochiai A; Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Suzuki K; Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

المصدر: Pathology international [Pathol Int] 2021 Aug; Vol. 71 (8), pp. 512-520. Date of Electronic Publication: 2021 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Blackwell Scientific Publications for the Japanese Society of Pathology Country of Publication: Australia NLM ID: 9431380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1827 (Electronic) Linking ISSN: 13205463 NLM ISO Abbreviation: Pathol Int Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/therapy , Induction Chemotherapy* , Tumor Microenvironment*, Biomarkers, Tumor/metabolism ; Cancer-Associated Fibroblasts/metabolism ; Cancer-Associated Fibroblasts/pathology ; Chemoradiotherapy ; Female ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Lung/pathology ; Lung Neoplasms/pathology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Scavenger Receptors, Class A/metabolism ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/pathology

المؤلفون: Okubo S; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.; Hepato-Biliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon Hospital, Japan., Suzuki T; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.; General Medicinal Education and Research Center, Teikyo University, Tokyo, Japan., Hioki M; Department of Gastroenterological Surgery, Fukuyama City Hospital, Hiroshima, Japan., Shimizu Y; Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan., Toyama H; Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Hyogo, Japan., Morinaga S; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan., Gotohda N; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan., Uesaka K; Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan., Takahashi S; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan., Kojima M; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.

المصدر: Cancer science [Cancer Sci] 2021 Jul; Vol. 112 (7), pp. 2895-2904. Date of Electronic Publication: 2021 May 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

مواضيع طبية MeSH: Chemoradiotherapy, Adjuvant* , Immunity, Cellular*, Carcinoma, Pancreatic Ductal/*therapy , Pancreatic Neoplasms/*therapy , Tumor Microenvironment/*immunology, Aged ; Antigens, CD20 ; B-Lymphocytes/immunology ; CD4 Lymphocyte Count ; Carcinoma, Pancreatic Ductal/immunology ; Carcinoma, Pancreatic Ductal/surgery ; Female ; Forkhead Transcription Factors/immunology ; Humans ; Immunohistochemistry/methods ; Lymphocyte Count ; Macrophages/immunology ; Male ; Middle Aged ; Multivariate Analysis ; Neoadjuvant Therapy/methods ; Neoplasm Recurrence, Local/immunology ; Pancreatic Neoplasms/immunology ; Pancreatic Neoplasms/surgery ; Preoperative Care

المؤلفون: Ishii T; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.; Courses of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, National Cancer Center, Kashiwa, Chiba, Japan., Suzuki A; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan., Kuwata T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, National Cancer Center, Kashiwa, Chiba, Japan., Hisamitsu S; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Hashimoto H; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ohara Y; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Yanagihara K; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Mitsunaga S; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Yoshino T; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kinoshita T; Department of Gastric Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ochiai A; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Shitara K; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Chiba, Japan. gishii@east.ncc.go.jp.; Courses of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Tokyo, Japan. gishii@east.ncc.go.jp.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, National Cancer Center, Kashiwa, Chiba, Japan. gishii@east.ncc.go.jp.

المصدر: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2021 Jul; Vol. 24 (4), pp. 810-822. Date of Electronic Publication: 2021 Apr 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 100886238 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3305 (Electronic) Linking ISSN: 14363291 NLM ISO Abbreviation: Gastric Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Cancer-Associated Fibroblasts/*drug effects , Fluorouracil/*administration & dosage , Oxaliplatin/*administration & dosage , Stomach Neoplasms/*drug therapy , Tumor Microenvironment/*drug effects, Cell Line, Tumor ; Cell Movement/drug effects ; Gene Expression/drug effects ; Humans ; Hydrazines/administration & dosage ; Morpholines/antagonists & inhibitors ; Quinoxalines/administration & dosage ; Stomach/cytology ; Stomach/pathology

المؤلفون: Ishii G; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. gishi@east.ncc.go.jp.; Division of Innovative Pathology and Laboratory Medicine, Exploratory Oncology Research and Clinical Trial Center, Chiba, Japan. gishi@east.ncc.go.jp., Ishii T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Division of Innovative Pathology and Laboratory Medicine, Exploratory Oncology Research and Clinical Trial Center, Chiba, Japan.; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

المصدر: Human cell [Hum Cell] 2020 Oct; Vol. 33 (4), pp. 938-945. Date of Electronic Publication: 2020 Aug 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-0774 (Electronic) Linking ISSN: 09147470 NLM ISO Abbreviation: Hum Cell Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasm Recurrence, Local* , Tumor Microenvironment*/drug effects, Cancer-Associated Fibroblasts/*drug effects , Cancer-Associated Fibroblasts/*pathology , Neoplasms/*drug therapy , Neoplasms/*pathology, Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Humans ; Neoplasms/physiopathology ; Stromal Cells

المؤلفون: Ichikawa T; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Miyoshi T; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Tane K; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Suzuki K; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Makinoshima H; Tsuruoka Metabolomics Laboratory, National Cancer Center, Tsuruoka, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan. Electronic address: gishi@east.ncc.go.jp.

المصدر: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2019 Oct; Vol. 136, pp. 57-64. Date of Electronic Publication: 2019 Aug 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Fluorodeoxyglucose F18* , Positron-Emission Tomography* , Tumor Microenvironment*, Adenocarcinoma of Lung/*diagnostic imaging , Adenocarcinoma of Lung/*pathology, Adenocarcinoma of Lung/mortality ; Adult ; Aged ; Aged, 80 and over ; Biomarkers ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Neoplasm Staging ; Positron Emission Tomography Computed Tomography ; Radiography ; Stromal Cells/metabolism ; Stromal Cells/pathology ; Tomography, X-Ray Computed

المؤلفون: Hisamitsu S; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan., Miyashita T; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan., Hashimoto H; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan., Neri S; Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan., Sugano M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan., Nakamura H; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan., Yamazaki S; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan., Ochiai A; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Goto K; Department of Thoracic Oncology, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Ishii G; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan. gishii@east.ncc.go.jp.; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Chiba, Japan. gishii@east.ncc.go.jp.

المصدر: Human cell [Hum Cell] 2019 Oct; Vol. 32 (4), pp. 453-464. Date of Electronic Publication: 2019 Aug 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-0774 (Electronic) Linking ISSN: 09147470 NLM ISO Abbreviation: Hum Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation* , Tumor Microenvironment*, Adenocarcinoma/*pathology , Antineoplastic Agents/*pharmacology , Cancer-Associated Fibroblasts/*pathology , Cisplatin/*pharmacology , Lung Neoplasms/*pathology, A549 Cells ; Epithelial-Mesenchymal Transition/drug effects ; Epithelial-Mesenchymal Transition/genetics ; Humans ; Transforming Growth Factor beta1/physiology

المؤلفون: Ueda T; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan. Electronic address: kaokage@east.ncc.go.jp., Mimaki S; Division of Translational Research, Research Center for Innovate Oncology, National Cancer Center, Kashiwa, Japan., Tane K; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Miyoshi T; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Sugano M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan., Kojima M; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Fujii S; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Kuwata T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan., Ochiai A; Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Kusumoto M; Department of Diagnostic Radiology, National Cancer Center Hospital East, Chiba, Japan., Suzuki K; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Tsuchihara K; Division of Translational Research, Research Center for Innovate Oncology, National Cancer Center, Kashiwa, Japan., Nishikawa H; Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Goto K; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan. Electronic address: gishii@east.ncc.go.jp.

المصدر: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2018 Dec; Vol. 126, pp. 162-169. Date of Electronic Publication: 2018 Nov 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*immunology , Idiopathic Pulmonary Fibrosis/*immunology , Lung Neoplasms/*immunology , Tumor Microenvironment/*immunology, Adenocarcinoma/complications ; Adult ; Aged ; Aged, 80 and over ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Female ; Forkhead Transcription Factors/immunology ; Forkhead Transcription Factors/metabolism ; Humans ; Idiopathic Pulmonary Fibrosis/complications ; Kaplan-Meier Estimate ; Lung Neoplasms/complications ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Male ; Middle Aged ; Prognosis ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Young Adult

المؤلفون: Katsumata S; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Tokyo, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Miyoshi T; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Tane K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Nakamura H; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Sugano M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kojima M; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Fujii S; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Kuwata T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ochiai A; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Hayashi R; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan. Electronic address: gishii@east.ncc.go.jp.

المصدر: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2018 Oct; Vol. 156 (4), pp. 1679-1688.e2. Date of Electronic Publication: 2018 Jun 04.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0376343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-685X (Electronic) Linking ISSN: 00225223 NLM ISO Abbreviation: J Thorac Cardiovasc Surg Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Microenvironment*, Adenocarcinoma of Lung/*pathology , Lung Neoplasms/*pathology, Adenocarcinoma of Lung/chemistry ; Adenocarcinoma of Lung/surgery ; Aged ; Biomarkers, Tumor/analysis ; Biopsy ; Cancer-Associated Fibroblasts/chemistry ; Cancer-Associated Fibroblasts/pathology ; Female ; Humans ; Immunohistochemistry ; Lung Neoplasms/chemistry ; Lung Neoplasms/surgery ; Macrophages/chemistry ; Macrophages/pathology ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplastic Stem Cells/chemistry ; Neoplastic Stem Cells/pathology ; Retrospective Studies ; Stromal Cells/chemistry ; Stromal Cells/pathology ; Tumor Burden ; Tumor Hypoxia

المؤلفون: Ueda T; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan.; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Aokage K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Nishikawa H; Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Neri S; Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan., Nakamura H; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan.; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Sugano M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan., Tane K; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Miyoshi T; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Kojima M; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Fujii S; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Kuwata T; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan., Ochiai A; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan., Kusumoto M; Department of Diagnostic Radiology, National Cancer Center Hospital East, Chiba, Japan., Suzuki K; Departments of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan., Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan., Ishii G; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. gishii@east.ncc.go.jp.

المصدر: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2018 May; Vol. 144 (5), pp. 835-844. Date of Electronic Publication: 2018 Feb 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1335 (Electronic) Linking ISSN: 01715216 NLM ISO Abbreviation: J Cancer Res Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Squamous Cell/*immunology , Idiopathic Pulmonary Fibrosis/*immunology , Immune Tolerance/*immunology , Lung Neoplasms/*immunology , Tumor Microenvironment/*immunology, Adult ; Aged ; Aged, 80 and over ; B7-H1 Antigen/immunology ; B7-H1 Antigen/metabolism ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Female ; Gene Expression Profiling/methods ; Humans ; Idiopathic Pulmonary Fibrosis/genetics ; Idiopathic Pulmonary Fibrosis/metabolism ; Immune Tolerance/genetics ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lymphocyte Subsets/immunology ; Lymphocyte Subsets/metabolism ; Male ; Middle Aged ; Prognosis ; Tumor Microenvironment/genetics