المؤلفون: Tacconi C; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland., Ungaro F; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Correale C; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Arena V; Department of Internal Medicine, Catholic University of Rome, Rome, Italy., Massimino L; School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland., Spinelli A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.; Colon and Rectal Surgery Department, Humanitas Research Hospital, Rozzano, Italy., Carvello M; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.; Colon and Rectal Surgery Department, Humanitas Research Hospital, Rozzano, Italy., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Leuven, Belgium.; Lab of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Oliveira AI; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Leuven, Belgium.; Lab of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Rubbino F; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Garlatti V; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Spanò S; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Lugli E; Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Italy.; Humanitas Flow Cytometry Core, Humanitas Clinical and Research Center, Rozzano, Italy., Colombo FS; Humanitas Flow Cytometry Core, Humanitas Clinical and Research Center, Rozzano, Italy., Malesci A; Department of Biotechnologies and Translational Medicine, University of Milan, Rozzano (Milan), Italy.; Department of Gastroenterology, Humanitas Clinical and Research Center, Rozzano (Milan), Italy., Peyrin-Biroulet L; Institut National de la Santé et de la Recherche Médicale U954 and Department of Gastroenterology, Nancy University Hospital, Lorraine University, Nancy, France., Vetrano S; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Danese S; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., D'Alessio S; Laboratory of Gastrointestinal Immunopathology, Humanitas Clinical and Research Center, Rozzano, Italy. silvia.dalessio@hunimed.eu.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.

المصدر: Cancer research [Cancer Res] 2019 Aug 15; Vol. 79 (16), pp. 4196-4210. Date of Electronic Publication: 2019 Jun 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Escape*, Colorectal Neoplasms/*immunology , Vascular Endothelial Growth Factor C/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*metabolism, Animals ; Cancer Vaccines/pharmacology ; Colorectal Neoplasms/metabolism ; Female ; Humans ; Lymphatic Vessels/metabolism ; Lymphatic Vessels/pathology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology

المؤلفون: Schwager S; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.

المصدر: Frontiers in immunology [Front Immunol] 2019 Feb 26; Vol. 10, pp. 308. Date of Electronic Publication: 2019 Feb 26 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Inflammation/*metabolism , Lymphatic Vessels/*metabolism , Vascular Endothelial Growth Factor C/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*metabolism, Animals ; Arthritis, Rheumatoid/metabolism ; Humans ; Inflammatory Bowel Diseases/metabolism ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Gousopoulos E; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Proulx ST; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Bachmann SB; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Dieterich LC; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Scholl J; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Karaman S; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Bianchi R; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland. Electronic address: michael.detmar@pharma.ethz.ch.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2017 Sep; Vol. 137 (9), pp. 1995-2004. Date of Electronic Publication: 2017 May 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Lymphedema/*metabolism , Lymphedema/*physiopathology , Vascular Endothelial Growth Factor C/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*metabolism, Animals ; Biomarkers/metabolism ; Cells, Cultured ; Disease Models, Animal ; Female ; Flow Cytometry ; Humans ; Lymphatic Vessels/metabolism ; Lymphatic Vessels/pathology ; Macrophages/metabolism ; Mice ; Mice, Transgenic ; Random Allocation ; Role

المؤلفون: Dieterich LC; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland., Ducoli L; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland., Shin JW; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, 8093 Zurich, Switzerland.

المصدر: Scientific data [Sci Data] 2017 Aug 29; Vol. 4, pp. 170106. Date of Electronic Publication: 2017 Aug 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101640192 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4463 (Electronic) Linking ISSN: 20524463 NLM ISO Abbreviation: Sci Data Subsets: MEDLINE

مواضيع طبية MeSH: Endothelial Cells*/drug effects , Endothelial Cells*/metabolism , Transcriptional Activation* , Vascular Endothelial Growth Factor Receptor-2* , Vascular Endothelial Growth Factor Receptor-3*, Datasets as Topic ; Gene Expression Profiling ; Humans

المؤلفون: Proulx ST, Ma Q, Andina D, Leroux JC, Detmar M

المصدر: JCI insight [JCI Insight] 2017 Jan 12; Vol. 2 (1), pp. e90861. Date of Electronic Publication: 2017 Jan 12.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Print ISSN: 2379-3708 (Print) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Lymphatic Vessels/*anatomy & histology , Optical Imaging/*methods , Vascular Endothelial Growth Factor C/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*metabolism, Animals ; Infrared Rays ; Lymphatic Vessels/diagnostic imaging ; Lymphatic Vessels/metabolism ; Lymphatic Vessels/physiopathology ; Mice ; Mice, Transgenic

المؤلفون: Ochsenbein AM; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Karaman S; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Proulx ST; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Goldmann R; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Chittazhathu J; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Dasargyri A; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Chong C; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Leroux JC; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland., Stanley ER; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Yeshiva University, New York, NY, 10461, USA., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Vladimir-Prelog-Weg 3, HCI H303, 8093, Zurich, Switzerland. michael.detmar@pharma.ethz.ch.

المصدر: Angiogenesis [Angiogenesis] 2016 Oct; Vol. 19 (4), pp. 513-24. Date of Electronic Publication: 2016 Jul 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9814575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7209 (Electronic) Linking ISSN: 09696970 NLM ISO Abbreviation: Angiogenesis Subsets: MEDLINE

مواضيع طبية MeSH: Diaphragm/*growth & development , Lymphangiogenesis/*physiology , Macrophages/*physiology , Vascular Endothelial Growth Factor Receptor-3/*physiology, Animals ; Animals, Newborn ; Cells, Cultured ; Culture Media, Conditioned ; Diaphragm/cytology ; Diaphragm/physiology ; Female ; Lymphatic Vessels/cytology ; Lymphatic Vessels/physiology ; Macrophages/cytology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/antagonists & inhibitors ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/deficiency ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/genetics ; Signal Transduction ; Vascular Endothelial Growth Factor Receptor-3/antagonists & inhibitors

المؤلفون: Klein S; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich 8093, Switzerland., Dieterich LC; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich 8093, Switzerland., Mathelier A; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University British Columbia, Vancouver, British Columbia, Canada V5Z 4H4., Chong C; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich 8093, Switzerland., Sliwa-Primorac A; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich 8093, Switzerland., Hong YK; Division of Plastic and Reconstructive Surgery, Department of Surgery, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Shin JW; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Lizio M; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Itoh M; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Kawaji H; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Lassmann T; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan Telethon Kids Institute, The University of Western Australia, Subiaco, Western Australia 6008, Australia., Daub CO; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Arner E; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Carninci P; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan., Hayashizaki Y; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Saitama 351-0198, Japan., Forrest AR; RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa 230-0045, Japan Cancer and Cell Biology Division, Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, the University of Western Australia, Nedlands, Western Australia 6009, Australia., Wasserman WW; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University British Columbia, Vancouver, British Columbia, Canada V5Z 4H4., Detmar M; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich 8093, Switzerland michael.detmar@pharma.ethz.ch.

مؤلفون مشاركون: FANTOM consortium

المصدر: Journal of cell science [J Cell Sci] 2016 Jul 01; Vol. 129 (13), pp. 2573-85. Date of Electronic Publication: 2016 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Homeodomain Proteins/*genetics , Neoplasms/*genetics , Nuclear Receptor Subfamily 4, Group A, Member 1/*genetics , Transcription Factors/*genetics , Vascular Endothelial Growth Factor C/*genetics , Vascular Endothelial Growth Factor Receptor-3/*genetics, Cell Line ; Cell Membrane Permeability/genetics ; Cell Movement/genetics ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphangiogenesis/genetics ; Neoplasm Metastasis ; Neoplasms/pathology ; Signal Transduction ; Vascular Endothelial Growth Factor C/biosynthesis ; Vascular Endothelial Growth Factor Receptor-3/biosynthesis

المؤلفون: Jurisic G; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland., Sundberg JP, Detmar M

المصدر: Inflammatory bowel diseases [Inflamm Bowel Dis] 2013 Aug; Vol. 19 (9), pp. 1983-9.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Lymphangiogenesis*, Inflammatory Bowel Diseases/*pathology , Interleukin-10/*physiology , Lymphatic Vessels/*pathology , Vascular Endothelial Growth Factor Receptor-3/*antagonists & inhibitors, Animals ; Humans ; Immunoenzyme Techniques ; Inflammatory Bowel Diseases/metabolism ; Lymphatic Vessels/metabolism ; Mice ; Mice, Knockout ; Vascular Endothelial Growth Factor Receptor-3/metabolism

المؤلفون: Huggenberger R; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, 8093 Zurich, Switzerland., Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M

المصدر: The Journal of experimental medicine [J Exp Med] 2010 Sep 27; Vol. 207 (10), pp. 2255-69. Date of Electronic Publication: 2010 Sep 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: Lymphangiogenesis*, Dermatitis/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*antagonists & inhibitors, Animals ; Antibodies, Blocking/immunology ; CD8-Positive T-Lymphocytes/immunology ; Chronic Disease ; Dermatitis/genetics ; Dermatitis/immunology ; Dermatitis/therapy ; Keratin-14/genetics ; Mice ; Mice, Transgenic ; Skin/blood supply ; Skin/immunology ; Skin/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor D/administration & dosage ; Vascular Endothelial Growth Factor D/immunology ; Vascular Endothelial Growth Factor Receptor-2/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-2/immunology ; Vascular Endothelial Growth Factor Receptor-3/immunology ; Vascular Endothelial Growth Factor Receptor-3/metabolism

المؤلفون: Rinderknecht M; Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland., Villa A, Ballmer-Hofer K, Neri D, Detmar M

المصدر: PloS one [PLoS One] 2010 Aug 02; Vol. 5 (8), pp. e11941. Date of Electronic Publication: 2010 Aug 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Peptide Library*, Antibodies, Monoclonal/*immunology , Single-Chain Antibodies/*immunology , Vascular Endothelial Growth Factor C/*immunology , Vascular Endothelial Growth Factor C/*metabolism , Vascular Endothelial Growth Factor Receptor-2/*metabolism , Vascular Endothelial Growth Factor Receptor-3/*metabolism, Amino Acid Sequence ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/metabolism ; Antibody Affinity ; Antibody Specificity ; Enzyme-Linked Immunosorbent Assay ; Humans ; Hydrophobic and Hydrophilic Interactions ; Immunoglobulin Heavy Chains/immunology ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Protein Binding/immunology ; Protein Multimerization ; Protein Stability ; Protein Structure, Quaternary ; Single-Chain Antibodies/chemistry ; Single-Chain Antibodies/genetics ; Single-Chain Antibodies/metabolism ; Vascular Endothelial Growth Factor C/chemistry