المؤلفون: Mega JL; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: jmega@partners.org., Walker JR; Celgene Corporation, Summit, NJ, USA., Ruff CT; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Vandell AG; Daiichi Sankyo Pharma Development, Edison, NJ, USA., Nordio F; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Deenadayalu N; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Murphy SA; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lee J; Daiichi Sankyo Pharma Development, Edison, NJ, USA., Mercuri MF; Daiichi Sankyo Pharma Development, Edison, NJ, USA., Giugliano RP; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Antman EM; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Braunwald E; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Sabatine MS; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: msabatine@partners.org.

المصدر: Lancet (London, England) [Lancet] 2015 Jun 06; Vol. 385 (9984), pp. 2280-7. Date of Electronic Publication: 2015 Mar 11.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE

مواضيع طبية MeSH: Anticoagulants/*therapeutic use , Atrial Fibrillation/*drug therapy , Atrial Fibrillation/*genetics , Factor Xa Inhibitors/*therapeutic use , Pyridines/*therapeutic use , Thiazoles/*therapeutic use , Warfarin/*therapeutic use, Anticoagulants/administration & dosage ; Anticoagulants/adverse effects ; Atrial Fibrillation/complications ; Cytochrome P-450 CYP2C9/genetics ; Double-Blind Method ; Factor Xa Inhibitors/administration & dosage ; Genetic Variation ; Genotype ; Hemorrhage/chemically induced ; Humans ; International Normalized Ratio ; Pharmacogenetics ; Pyridines/administration & dosage ; Risk Assessment ; Stroke/prevention & control ; Thiazoles/administration & dosage ; Vitamin K Epoxide Reductases/genetics ; Warfarin/administration & dosage ; Warfarin/adverse effects

المؤلفون: Mega JL; Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. jmega@partners.org., Giugliano RP; Thrombolysis in Myocardial Infarction Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

المصدر: Clinical chemistry [Clin Chem] 2014 Jul; Vol. 60 (7), pp. 920-2. Date of Electronic Publication: 2014 Apr 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9421549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-8561 (Electronic) Linking ISSN: 00099147 NLM ISO Abbreviation: Clin Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anticoagulants/*agonists , Warfarin/*administration & dosage, Aryl Hydrocarbon Hydroxylases/genetics ; Atrial Fibrillation/blood ; Atrial Fibrillation/drug therapy ; Clinical Trials as Topic ; Cytochrome P-450 CYP2C9 ; Drug Monitoring ; Genotype ; Humans ; International Normalized Ratio ; Venous Thromboembolism/blood ; Venous Thromboembolism/drug therapy ; Vitamin K Epoxide Reductases/genetics