المؤلفون: Chen K; Dizal Pharmaceuticals, Shanghai, China., Guan X; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing, China.; Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Yang Z; Dizal Pharmaceuticals, Shanghai, China., Zhou Y; Dizal Pharmaceuticals, Shanghai, China., Liu Z; Dizal Pharmaceuticals, Shanghai, China., Deng X; Dizal Pharmaceuticals, Shanghai, China., Liu D; Dizal Pharmaceuticals, Shanghai, China., Hu P; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing, China.; Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Chen R; Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing, China.; Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

المصدر: Frontiers in immunology [Front Immunol] 2023 Apr 03; Vol. 14, pp. 1127935. Date of Electronic Publication: 2023 Apr 03 (Print Publication: 2023).

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Asian People* , Janus Kinase 1*/antagonists & inhibitors , Janus Kinase Inhibitors*/pharmacokinetics , Biological Availability* , White People* , Black People*, Adult ; Humans ; Administration, Oral ; Area Under Curve ; Half-Life ; Healthy Volunteers ; STAT3 Transcription Factor/antagonists & inhibitors ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Fasting ; China ; United States ; Internationality ; Multicenter Studies as Topic

المؤلفون: Fang L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Uppoor R; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Xu M; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Sharan S; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Zhu H; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Tampal N; Office of Bioequivalence, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Li B; Office of Bioequivalence, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Zhang L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Lionberger R; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Zhao L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Oct; Vol. 110 (4), pp. 880-887. Date of Electronic Publication: 2021 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Area Under Curve* , Biological Availability* , Drug and Narcotic Control* , Therapeutic Equivalency*, Abuse-Deterrent Formulations ; Delayed-Action Preparations/pharmacokinetics ; Humans ; Pharmacokinetics ; United States ; United States Food and Drug Administration

المؤلفون: Connolly G; Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA., Hudson JL; Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA., Bergia RE; Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA., Davis EM; Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA., Hartman AS; Department of Statistics, Purdue University, West Lafayette, IN 47907, USA., Zhu W; Department of Statistics, Purdue University, West Lafayette, IN 47907, USA., Carroll CC; Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47907, USA., Campbell WW; Department of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.

المصدر: Nutrients [Nutrients] 2023 Jun 25; Vol. 15 (13). Date of Electronic Publication: 2023 Jun 25.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids, Essential* , Nutrition Policy*, Animals ; Humans ; Biological Availability ; Eggs ; Randomized Controlled Trials as Topic ; United States ; Cross-Over Studies

المؤلفون: Wymer J; University of Florida, Gainesville, Florida, USA., Apple S; Mitsubishi Tanabe Pharma America, Inc., Jersey City, New Jersey, USA., Harrison A; Mitsubishi Tanabe Pharma America, Inc., Jersey City, New Jersey, USA., Hill BA; Mitsubishi Tanabe Pharma America, Inc., Jersey City, New Jersey, USA.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Jan; Vol. 12 (1), pp. 57-64. Date of Electronic Publication: 2022 Sep 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Riluzole*/adverse effects , Amyotrophic Lateral Sclerosis*/drug therapy , Amyotrophic Lateral Sclerosis*/chemically induced, United States ; Humans ; Biological Availability ; Deglutition ; Cross-Over Studies

المؤلفون: Zhai BT; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Sun J; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Shi YJ; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Zhang XF; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Zou JB; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Cheng JX; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Fan Y; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China., Guo DY; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China. 2051080@sntcm.edu.cn., Tian H; Xi'an Hospital of Traditional Chinese Medicine, Xi'an, 710021, China. 18149412681@163.com.

المصدر: Journal of nanobiotechnology [J Nanobiotechnology] 2022 Dec 03; Vol. 20 (1), pp. 509. Date of Electronic Publication: 2022 Dec 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE

مواضيع طبية MeSH: Bridged Bicyclo Compounds, Heterocyclic* , Neoplasms*/drug therapy, United States ; Drug Delivery Systems ; Half-Life ; Biological Availability

المؤلفون: Burgess RM; US EPA ORD, CEMM, Atlantic Coastal Environmental Sciences Division, Narragansett, Rhode Island, USA., Grossman S; US EPA OLEM, OSRTI, Environmental Response Team, Edison, New Jersey, USA., Ball G; US EPA OLEM, OSRTI, Environmental Response Team, Edison, New Jersey, USA., Kady T; US EPA OLEM, OSRTI, Environmental Response Team, Edison, New Jersey, USA., Sprenger M; US EPA OLEM, OSRTI, Environmental Response Team, Edison, New Jersey, USA., Nevshehirlian S; US EPA OSSR, HSCD, Region 3, Philadelphia, Pennsylvania, USA.

المصدر: Integrated environmental assessment and management [Integr Environ Assess Manag] 2021 Nov; Vol. 17 (6), pp. 1215-1228. Date of Electronic Publication: 2021 May 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Society of Environmental Toxicology and Chemistry (SETAC) Country of Publication: United States NLM ID: 101234521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-3793 (Electronic) Linking ISSN: 15513777 NLM ISO Abbreviation: Integr Environ Assess Manag Subsets: MEDLINE

مواضيع طبية MeSH: Polycyclic Aromatic Hydrocarbons*/analysis , Water Pollutants, Chemical*/analysis, Biological Availability ; Delaware ; Environmental Monitoring ; Geologic Sediments ; United States

المؤلفون: Gentry R; Ramboll US Consulting Inc., Monroe, LA, 71201, USA. Electronic address: rgentry@ramboll.com., Greene T; Ramboll US Consulting Inc., Monroe, LA, 71201, USA., Chappell G; ToxStrategies Inc., Asheville, NC, 28801, USA., Lea I; ToxStrategies Inc., Asheville, NC, 28801, USA., Borghoff S; ToxStrategies Inc., Cary, NC, 27511, USA., Yang C; Altamira LLC & Molecular Networks GmbH, Columbus, OH, 43235, USA., Rathman J; Altamira LLC & Molecular Networks GmbH, Columbus, OH, 43235, USA., Ribeiro JV; Altamira LLC & Molecular Networks GmbH, Columbus, OH, 43235, USA., Hobocienski B; Altamira LLC & Molecular Networks GmbH, Columbus, OH, 43235, USA., Mostrag A; Altamira LLC & Molecular Networks GmbH, Columbus, OH, 43235, USA., Rodricks J; Ramboll US Consulting Inc., Arlington, VA, 22203, USA., Clewell H; Ramboll US Consulting Inc., Monroe, LA, 71201, USA.

المصدر: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 May; Vol. 151, pp. 112097. Date of Electronic Publication: 2021 Mar 04.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Behavior, Animal/*drug effects , Drug Approval/*legislation & jurisprudence , Food Coloring Agents/*adverse effects , Nervous System/*drug effects, Animals ; Biological Availability ; Brain/metabolism ; Food Coloring Agents/pharmacokinetics ; Humans ; No-Observed-Adverse-Effect Level ; United States ; United States Food and Drug Administration

المؤلفون: Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA. pgurbel@lifebridgehealth.org., Bliden KP; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA., Rout A; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA., Rapista N; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA., Walia N; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA., Chaudhary R; Division of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA., Ens G; Inflammatory Markers Laboratory, Wichita, KS, USA., Traianova M; CEDEX Laboratory, Nashua, NH, USA., Barnes JS; Critical Care Medicine, Sinai Hospital and Northwest Hospital, Lifebridge Health, Baltimore, MD, USA., Tantry US; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.

المصدر: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2021 May; Vol. 51 (4), pp. 902-904. Date of Electronic Publication: 2021 Apr 07.

نوع المنشور: Journal Article; Observational Study

بيانات الدورية: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9502018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-742X (Electronic) Linking ISSN: 09295305 NLM ISO Abbreviation: J Thromb Thrombolysis Subsets: MEDLINE

مواضيع طبية MeSH: Anticoagulants*/administration & dosage , Anticoagulants*/pharmacokinetics , Aspirin*/administration & dosage , Aspirin*/pharmacokinetics , COVID-19*/blood , COVID-19*/diagnosis , COVID-19*/physiopathology , Heparin*/administration & dosage , Heparin*/pharmacokinetics , COVID-19 Drug Treatment*, Biomarkers, Pharmacological/*blood , Point-of-Care Testing/*statistics & numerical data , Thrombelastography/*methods, Black or African American/statistics & numerical data ; Biological Availability ; Female ; Hemostasis/drug effects ; Hemostasis/physiology ; Humans ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/pharmacokinetics ; Platelet Function Tests/methods ; Platelet Function Tests/statistics & numerical data ; SARS-CoV-2 ; United States/epidemiology

المؤلفون: Uttaro E; Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY, USA., Pudipeddi M; Parakam Pharma LLC, Plano, TX, USA., Schweighardt A; Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY, USA.; University of Rochester Medical Center, Rochester, NY, USA., Zhao F; University of Rochester Medical Center, Rochester, NY, USA.

المصدر: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2021 Feb 19; Vol. 78 (5), pp. 389-394.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium: Internet ISSN: 1535-2900 (Electronic) Linking ISSN: 10792082 NLM ISO Abbreviation: Am J Health Syst Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Nanoparticles*, Biological Availability ; Capsules ; Humans ; Tablets ; United States

المؤلفون: Yang Y; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA. Electronic address: yang.yang@fda.hhs.gov., Ako-Adounvo AM; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Wang J; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Zhang J; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Willett D; Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Missouri, USA., Yilmaz H; Division of Complex Drug Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Missouri, USA., Korang-Yeboah M; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Hsu HJ; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Wang J; Office of Drug Evaluation IV, Office New Drugs, Center for Drug Evaluation and Research, FDA, Maryland, USA., Coelho SG; Division of Nonprescription Drug Products, Office of Drug Evaluation IV, Office New Drugs, Center for Drug Evaluation and Research, FDA, Maryland, USA., Adah SA; Division of Nonprescription Drug Products, Office of Drug Evaluation IV, Office New Drugs, Center for Drug Evaluation and Research, FDA, Maryland, USA., Michele TM; Division of Nonprescription Drug Products, Office of Drug Evaluation IV, Office New Drugs, Center for Drug Evaluation and Research, FDA, Maryland, USA., Faustino PJ; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Cruz CN; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Lee S; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA., Ashraf M; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA, Maryland, USA.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2020 Dec; Vol. 140 (12), pp. 2487-2495. Date of Electronic Publication: 2020 Apr 28.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Skin Absorption*, Drug Evaluation, Preclinical/*methods , Skin/*metabolism , Sunscreening Agents/*pharmacokinetics, Administration, Cutaneous ; Aged ; Aged, 80 and over ; Biological Availability ; Cadaver ; Clinical Trials as Topic/standards ; Drug Approval ; Emulsions/administration & dosage ; Emulsions/pharmacokinetics ; Female ; Humans ; In Vitro Techniques/methods ; Permeability ; Pilot Projects ; Skin/drug effects ; Skin/radiation effects ; Sunscreening Agents/administration & dosage ; Ultraviolet Rays/adverse effects ; United States ; United States Food and Drug Administration/standards