المؤلفون: Alcaide, Maria L., Feaster, Daniel J., Duan, Rui, Cohen, Stephanie, Diaz, Chanelle, Castro, Jose G., Golden, Matthew R., Henn, Sarah, Colfax, Grant N., Metsch, Lisa R.

المصدر: Sexually Transmitted Infections; Feb2016, Vol. 92 Issue 1, p58-62, 5p, 1 Chart

مصطلحات موضوعية: TRICHOMONAS vaginalis, TRICHOMONIASIS, SEXUALLY transmitted disease risk factors, HIV infection risk factors, PROTOZOAN diseases, BEHAVIOR, COMPARATIVE studies, COUNSELING, RESEARCH methodology, MEDICAL cooperation, PROTOZOA, RESEARCH, RESEARCH funding, EVALUATION research, RANDOMIZED controlled trials, DISEASE prevalence, SEXUAL partners, PREVENTION

مصطلحات جغرافية: UNITED States

مستخلص: Objectives: Trichomoniasis (TV) is associated with an increased risk of acquisition of sexually transmitted diseases (STDs) and HIV. The purpose of this study is to evaluate factors associated with incidence TV among female STD clinic attendees in the USA.Methods: Data were collected from women participating in a randomised controlled trial evaluating brief risk reduction counselling at the time of HIV testing to reduce sexually transmitted infections (STIs) incidence in STD clinics. Participants recruited from STD clinics underwent STI testing at baseline and 6-month follow-up. TV testing was performed using Nucleic Acid Amplification Test.Results: 1704 participants completed study assessments. Prevalence of TV was 14.6%, chlamydia 8.6%, gonorrhoea 3.0%, herpes simplex virus 2 44.7% and HIV 0.4%. Cumulative 6-month incidence of TV was 7.5%. Almost 50% of the incident TV cases had TV at baseline and had received treatment. Factors associated with incidence of TV were having chlamydia, TV and HIV at baseline: TV relative risk (RR)=3.37 (95% CI 2.35 to 4.83, p<0.001); chlamydia RR=1.92 (95% CI 1.23 to 2.99, p=0.04); and HIV=1.59 (95% CI 1.01 to 2.50, p=0.047).Conclusions: Prevalent and incident TV is common among STD clinic attendees; and baseline TV is the main risk factor for incident TV, suggesting high rates of reinfection or treatment failures. This supports the importance of rescreening women after treatment for TV, evaluating current treatment regimens and programmes to ensure treatment of sexual partners.Clinical Trial Number: NCT01154296. [ABSTRACT FROM AUTHOR]

: Copyright of Sexually Transmitted Infections is the property of BMJ Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Greene, Emily, Frye, Victoria, Mansergh, Gordon, Colfax, Grant, Hudson, Sharon, Flores, Stephen, Hoover, Donald, Bonner, Sebastian, Koblin, Beryl

المصدر: AIDS & Behavior; Mar2013, Vol. 17 Issue 3, p889-899, 11p, 3 Charts

مصطلحات موضوعية: HIV prevention, HIV infection risk factors, BISEXUALITY, CHI-squared test, CONFIDENCE intervals, EPIDEMIOLOGY, HOMOSEXUALITY, RESEARCH funding, STATISTICAL sampling, STATISTICS, SUBSTANCE abuse, U-statistics, DATA analysis, ANAL sex, MULTIPLE regression analysis, UNSAFE sex, DATA analysis software, DESCRIPTIVE statistics

مصطلحات جغرافية: UNITED States

مستخلص: The role men who have sex with men and women (MSMW) play in heterosexual HIV transmission is not well understood. We analyzed baseline data from Project MIX, a behavioral intervention study of substance-using men who have sex with men (MSM), and identified correlates of unprotected vaginal intercourse, anal intercourse, or both with women (UVAI). Approximately 10 % ( n = 194) of the men reported vaginal sex, anal sex, or both with a woman; of these substance-using MSMW, 66 % (129) reported UVAI. Among substance-using MSMW, multivariate analyses found unemployment relative to full/part-time employment (OR = 2.28; 95 % CI 1.01, 5.17), having a primary female partner relative to no primary female partner (OR = 3.44; CI 1.4, 8.46), and higher levels of treatment optimism (OR = 1.73; 95 % CI 1.18, 2.54) increased odds of UVAI. Strong feelings of connection to a same-race gay community (OR = 0.71; 95 % CI 0.56, 0.91) and Viagra use (OR = 0.31; 95 % CI 0.10, 0.95) decreased odds of UVAI. This work suggests that although the proportion of substance-using MSM who also have sex with women is low, these men engage in unprotected sex with women, particularly with primary female partners. This work highlights the need for further research with the substance using MSMW population to inform HIV prevention interventions specifically for MSMW. [ABSTRACT FROM AUTHOR]

: Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Tross, Susan, Campbell, Aimee N. C., Calsyn, Donald A., Metsch, Lisa R., Sorensen, James L., Shoptaw, Steven, Haynes, Louise, Woody, George E., Malow, Robert M., Brown, Lawrence S., Feaster, Daniel J., Booth, Robert E., Mandler, Raul N., Masson, Carmen, Holmes, Beverly W., Colfax, Grant, Brooks, Audrey J., Hien, Denise A., Schackman, Bruce R., Korthuis, P. Todd

المصدر: American Journal of Drug & Alcohol Abuse; 2011, Vol. 37 Issue 5, p283-293, 11p, 1 Chart

مصطلحات موضوعية: CLINICAL trials, SUBSTANCE abuse, HIV infections, AIDS, SUBSTANCE abuse treatment, MEDICAL protocols

مصطلحات جغرافية: UNITED States

الشركة/الكيان: NATIONAL Institute on Drug Abuse

مستخلص: Background/Objectives: HIV continues to be a significant problem among substance users and their sexual partners in the United States. The National Drug Abuse Treatment Clinical Trials Network (CTN) offers a national platform for effectiveness trials of HIV interventions in community substance abuse treatment programs. This article presents the HIV activities of the CTN during its first 10 years. Results: While emphasizing CTN HIV protocols, this article reviews the (1) HIV context for this work; (2) the collaborative process among providers, researchers, and National Institute on Drug Abuse CTN staff, on which CTN HIV work was based; (3) results of CTN HIV protocols and HIV secondary analyses in CTN non-HIV protocols; and (4) implications for future HIV intervention effectiveness research in community substance abuse treatment programs. Conclusion/Significance: While the feasibility of engaging frontline providers in this research is highlighted, the limitations of small to medium effect sizes and weak adoption and sustainability in everyday practice are also discussed. [ABSTRACT FROM AUTHOR]

: Copyright of American Journal of Drug & Alcohol Abuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Santos, Glenn-Milo, Das, Moupali, Colfax, Grant Nash

المصدر: AIDS & Behavior; Apr2011 Supplement 1, Vol. 15, p51-56, 6p

مصطلحات موضوعية: HIV infection risk factors, SUBSTANCE abuse treatment, GAY men, HIV infections, MEDICAL needs assessment, RISK-taking behavior, MOTIVATIONAL interviewing

مصطلحات جغرافية: UNITED States

مستخلص: The article describes interventions for non-injection substance among men who have sex with men (MSM) in the U.S. Trials focused on treatment-seeking, methamphetamine-dependent MSM are believed to reduce substance use and sexual risk behavior. The U.S. Food and Drug Administration has approved naltrexone for high prevalence of polysubstance use among substance using MSM. Pharmacotherapies are seen to have the most potential to be used in behavioral strategies. The Project ECHO study by the U.S. Centers for Disease Control and Prevention is discussed.

المؤلفون: Mansergh, Gordon, McKirnan, David J., Flores, Stephen A., Hudson, Sharon M., Koblin, Beryl A., Purcell, David W., Colfax, Grant N.

المصدر: Journal of Cognitive Psychotherapy; Winter2010, Vol. 24 Issue 4, p281-293, 13p, 3 Charts

مصطلحات موضوعية: HEALTH attitudes, HIV-positive men, MEN who have sex with men, SUBSTANCE abuse

مصطلحات جغرافية: UNITED States

مستخلص: This study compared HIV-related attitudes and intentions by respondent HIV-status in a large sample of substance-using men who have sex with men (MSM) in the United States. Attitudes and intentions included self-efficacy for safer sex; difficulty communicating with sex partners about safer sex; intent to use condoms consistently and to not use substances before sex in the next 3 months; and less concern for HIV given effective antiviral treatments. Differences were found for behavior during the most recent anal sex encounter by HIV-status, including (a) insertive and (b) receptive anal sex risk behavior, and (c) substance use before or during the encounter. Self-efficacy for safer sex was associated with less risk behavior among HIV-negative men but not among HIV-positive men, suggesting that self-efficacy for safer sex continues to be a relevant issue to address in counseling uninfected MSM. HIV-positive men who reported less concern for HIV given treatments were more likely to report receptive risk behavior, as were HIV-negative men who reported difficulty communicating about safer sex. Implications are discussed for potentially heightened client desire and therapeutic opportunity to reduce future substance use during sex for clients who report recent substance use during sex. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Cognitive Psychotherapy is the property of Springer Publishing Company, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Mansergh, Gordon, Koblin, Beryl A., McKirnan, David J., Hudson, Sharon M., Flores, Stephen A., Wiegand, Ryan E., Purcell, David W., Colfax, Grant N.

المصدر: PLoS Medicine; Aug2010, Vol. 7 Issue 8, p1-9, 9p, 1 Diagram, 3 Charts

مصطلحات موضوعية: HIV infection risk factors, MEN who have sex with men, DRUGS & sex, RISK-taking behavior, INTERVENTION (Social services), CHRONIC diseases, MENTAL health

مصطلحات جغرافية: UNITED States

مستخلص: Background: Substance use during sex is associated with sexual risk behavior among men who have sex with men (MSM), and MSM continue to be the group at highest risk for incident HIV in the United States. The objective of this study is to test the efficacy of a group-based, cognitive-behavioral intervention to reduce risk behavior of substance-using MSM, compared to a randomized attention-control group and a nonrandomized standard HIV-testing group. Methods and Findings: Participants (n = 1,686) were enrolled in Chicago, Los Angeles, New York City, and San Francisco and randomized to a cognitive-behavioral intervention or attention-control comparison. The nonrandomized group received standard HIV counseling and testing. Intervention group participants received six 2-h group sessions focused on reducing substance use and sexual risk behavior. Attention-control group participants received six 2-h group sessions of videos and discussion of MSM community issues unrelated to substance use, sexual risk, and HIV/AIDS. All three groups received HIV counseling and testing at baseline. The sample reported high-risk behavior during the past 3 mo prior to their baseline visit: 67% reported unprotected anal sex, and 77% reported substance use during their most recent anal sex encounter with a nonprimary partner. The three groups significantly (p,0.05) reduced risk behavior (e.g., unprotected anal sex reduced by 32% at 12-mo follow-up), but were not different (p.0.05) from each other at 3-, 6-, and 12-mo follow-up. Outcomes for the 2-arm comparisons were not significantly different at 12-mo follow-up (e.g., unprotected anal sex, odds ratio = 1.14, confidence interval = 0.86-1.51), nor at earlier time points. Similar results were found for each outcome variable in both 2- and 3-arm comparisons. Conclusions: These results for reducing sexual risk behavior of substance-using MSM are consistent with results of intervention trials for other populations, which collectively suggest critical challenges for the field of HIV behavioral interventions. Several mechanisms may contribute to statistically indistinguishable reductions in risk outcomes by trial group. More explicit debate is needed in the behavioral intervention field about appropriate scientific designs and methods. As HIV prevention increasingly competes for behavior-change attention alongside other ''chronic'' diseases and mental health issues, new approaches may better resonate with at-risk groups. [ABSTRACT FROM AUTHOR]

: Copyright of PLoS Medicine is the property of Public Library of Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Christopoulos, Katerina A., Das, Moupali, Colfax, Grant N.

المصدر: Clinical Infectious Diseases; 2011, Vol. 52 Issue suppl_2, pS214-S222, 1p

مصطلحات موضوعية: MEN who have sex with men, HEALTH outcome assessment, HIV infection risk factors, MEDICAL care, HIV-positive men, HEALTH

مصطلحات جغرافية: UNITED States

مستخلص: Men who have sex with men (MSM) continue to be disproportionately affected by human immunodeficiency virus (HIV) infection. While the MSM population does better than other HIV infection risk groups with regard to linkage to and retention in care, little is known about engagement in care outcomes for important subpopulations of MSM. There is also a dearth of research on engagement in care strategies specific to the MSM population. Key MSM subpopulations in the United States on which to focus future research efforts include racial/ethnic minority, young, and substance-using MSM. Health care systems navigation may offer a promising engagement in care strategy for MSM and should be further evaluated. As is the case for HIV-infected populations in general, future research should also focus on identifying the best metrics for measuring engagement in care. [ABSTRACT FROM PUBLISHER]

: Copyright of Clinical Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Sachdev DD; San Francisco Department of Public Health, San Francisco, CA, USA., Petersen M; Divisions of Biostatistics and Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Havlir DV; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Schwab J; Divisions of Biostatistics and Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Enanoria WTA; San Francisco Department of Public Health, San Francisco, CA, USA., Nguyen TQ; San Francisco Department of Public Health, San Francisco, CA, USA., Mercer MP; Department of Emergency Medicine, University of California, San Francisco, San Francisco, CA, USA., Scheer S; San Francisco Department of Public Health, San Francisco, CA, USA., Bennett A; San Francisco Department of Public Health, San Francisco, CA, USA., Tenner AG; San Francisco Department of Public Health, San Francisco, CA, USA., Marks JD; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA., Bobba N; San Francisco Department of Public Health, San Francisco, CA, USA., Philip S; San Francisco Department of Public Health, San Francisco, CA, USA., Colfax G; San Francisco Department of Public Health, San Francisco, CA, USA.

المصدر: Public health reports (Washington, D.C. : 1974) [Public Health Rep] 2023 Sep-Oct; Vol. 138 (5), pp. 747-755. Date of Electronic Publication: 2023 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9716844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2877 (Electronic) Linking ISSN: 00333549 NLM ISO Abbreviation: Public Health Rep Subsets: MEDLINE

مواضيع طبية MeSH: Pandemics*/prevention & control , COVID-19*/epidemiology, Humans ; United States ; San Francisco/epidemiology ; Ethnicity ; Residence Characteristics

مستخلص: San Francisco implemented one of the most intensive, comprehensive, multipronged COVID-19 pandemic responses in the United States using 4 core strategies: (1) aggressive mitigation measures to protect populations at risk for severe disease, (2) prioritization of resources in neighborhoods highly affected by COVID-19, (3) timely and adaptive data-driven policy making, and (4) leveraging of partnerships and public trust. We collected data to describe programmatic and population-level outcomes. The excess all-cause mortality rate in 2020 in San Francisco was half that seen in 2019 in California as a whole (8% vs 16%). In almost all age and race and ethnicity groups, excess mortality from COVID-19 was lower in San Francisco than in California overall, with markedly diminished excess mortality among people aged >65 years. The COVID-19 response in San Francisco highlights crucial lessons, particularly the importance of community responsiveness, joint planning, and collective action, to inform future pandemic response and advance health equity.

المؤلفون: Mansergh G; CDC Division of HIV/AIDS Prevention, Atlanta, Georgia, USA., Spikes P; CDC Division of HIV/AIDS Prevention, Atlanta, Georgia, USA., Flores SA; CDC Division of HIV/AIDS Prevention, Atlanta, Georgia, USA., Koblin BA; New York Blood Center, New York, New York, USA., McKirnan D; University of Illinois-Chicago, Chicago, Illinois, USA., Hudson SM; Health Research Association, Los Angeles, California, USA., Colfax GN; San Francisco Department of Public Health, San Francisco, California, USA.

مؤلفون مشاركون: Project MIX Study Group

المصدر: Sexually transmitted infections [Sex Transm Infect] 2015 Aug; Vol. 91 (5), pp. 324-8. Date of Electronic Publication: 2014 Dec 15.

نوع المنشور: Journal Article; Multicenter Study; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE

مواضيع طبية MeSH: Bisexuality/*psychology , HIV Seropositivity/*psychology , Homophobia/*psychology , Homosexuality, Male/*psychology , Sexual Behavior/*psychology , Sexual Partners/*psychology , Substance-Related Disorders/*psychology, Adult ; Bisexuality/ethnology ; Chicago/epidemiology ; Ethnicity ; HIV Seropositivity/complications ; Health Knowledge, Attitudes, Practice ; Homosexuality, Male/ethnology ; Humans ; Los Angeles/epidemiology ; Male ; New York/epidemiology ; Risk Factors ; Risk-Taking ; San Francisco/epidemiology ; Self Concept ; Sexual Behavior/ethnology ; Substance-Related Disorders/complications ; United States/epidemiology

مستخلص: Objectives: There is a continuing need to identify factors associated with risk for HIV transmission among men who have sex with men (MSM), including a need for further research in the ongoing scientific debate about the association of internalised homophobia and sexual risk due partly to the lack of specificity in analysis. We assess the association of internalised homophobia by race/ethnicity within HIV serostatus for a large sample of substance-using MSM at high risk of HIV acquisition or transmission.
Methods: Convenience sample of substance-using (non-injection) MSM reporting unprotected anal sex in the prior 6 months residing in Chicago, Los Angeles, New York and San Francisco. The analytic sample included HIV-negative and HIV-positive black (n=391), Latino (n=220), and white (n=458) MSM. Internalised homophobia was assessed using a published four-item scale focusing on negative self-perceptions and feelings of their own sexual behaviour with men, or for being gay or bisexual. Analyses tested associations of internalised homophobia with recent risk behaviour, stratified by laboratory-confirmed HIV serostatus within race/ethnicity, and controlling for other demographic variables.
Results: In multivariate analysis, internalised homophobia was inversely associated (p<0.05) with recent unprotected anal sex among black MSM, and not significantly associated with sexual risk behaviour among white and Latino MSM.
Conclusions: More research is needed to further identify nuanced differences in subpopulations of MSM, but these results suggest differentially targeted intervention messages for MSM by race/ethnicity.
(Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.)

المؤلفون: Eggman AA; From the *Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY; †Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL; ‡Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY; §Public Health-Seattle and King County, Seattle, WA; and ¶San Francisco Department of Public Health, San Francisco, CA., Feaster DJ, Leff JA, Golden MR, Castellon PC, Gooden L, Matheson T, Colfax GN, Metsch LR, Schackman BR

المصدر: Sexually transmitted diseases [Sex Transm Dis] 2014 Sep; Vol. 41 (9), pp. 545-50.

نوع المنشور: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: J B Lippincott Country of Publication: United States NLM ID: 7705941 Publication Model: Print Cited Medium: Internet ISSN: 1537-4521 (Electronic) Linking ISSN: 01485717 NLM ISO Abbreviation: Sex Transm Dis Subsets: MEDLINE

مواضيع طبية MeSH: Direct Service Costs* , Directive Counseling*/economics , Directive Counseling*/organization & administration , Reagent Kits, Diagnostic*/economics, Ambulatory Care Facilities/*organization & administration , HIV Seropositivity/*diagnosis , Mass Screening/*economics , Point-of-Care Systems/*economics , Practice Patterns, Nurses'/*economics, Adolescent ; Adult ; Aged ; Ambulatory Care Facilities/economics ; Cost-Benefit Analysis ; Delivery of Health Care ; Female ; HIV Seropositivity/economics ; Humans ; Male ; Middle Aged ; Point-of-Care Systems/organization & administration ; Practice Patterns, Nurses'/organization & administration ; United States

مستخلص: Introduction: Rapid HIV testing in high-risk populations can increase the number of persons who learn their HIV status and avoid spending clinic resources to locate persons identified as HIV infected.
Methods: We determined the cost to sexually transmitted disease (STD) clinics of point-of-care rapid HIV testing using data from 7 public clinics that participated in a randomized trial of rapid testing with and without brief patient-centered risk reduction counseling in 2010. Costs included counselor and trainer time, supplies, and clinic overhead. We applied national labor rates and test costs. We calculated median clinic start-up costs and mean cost per patient tested, and projected incremental annual costs of implementing universal rapid HIV testing compared with current testing practices.
Results: Criteria for offering rapid HIV testing and methods for delivering nonrapid test results varied among clinics before the trial. Rapid HIV testing cost an average of US $22/patient without brief risk reduction counseling and US $46/patient with counseling in these 7 clinics. Median start-up costs per clinic were US $1100 and US $16,100 without and with counseling, respectively. Estimated incremental annual costs per clinic of implementing universal rapid HIV testing varied by whether or not brief counseling is conducted and by current clinic testing practices, ranging from a savings of US $19,500 to a cost of US $40,700 without counseling and a cost of US $98,000 to US $153,900 with counseling.
Conclusions: Universal rapid HIV testing in STD clinics with same-day results can be implemented at relatively low cost to STD clinics, if brief risk reduction counseling is not offered.