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1دورية أكاديمية
المؤلفون: Kamil Krystkiewicz, Mateusz Maślanka, Tymon Skadorwa, Bogdan Ciszek, Marcin Tosik, Jacek Furtak
المصدر: Frontiers in Surgery, Vol 9 (2022)
مصطلحات موضوعية: disc herniation, meningovertebral ligaments, anterior epidural space, intervertebral disc, sciatica, meningovertebral ligaments in disc herniation, Surgery, RD1-811
الوصف: PurposeIntervertebral disc degeneration can manifest as sequestration. In most cases, the material could be found ipsilateral to the annular tear; however, a contralateral migration is also possible. We present an anatomical description of anterior meningovertebral ligaments (MVLs) as a possible barrier for disc migration.MethodsAnatomical dissection of 20 fresh human cadavers was carried out. Complete lumbar laminectomies with facetectomies were performed. All lumbar segments were exposed. Morphologic and morphometric descriptions of anterior MVLs were presented, with special attention to possible routes of herniated disc migration.ResultsAnterior MVLs were present in all cases. They were divided in three separate groups: medial, lateral, and attached to the nerve roots. The medial group was the thickest, its mean length was 26.2 ± 1.2 mm, and it had no attachment to the disc in 51% of cases. The lateral group was less firm than the medial group, its mean length was 26.9 ± 1.0 mm, and it had no relation with the disc in 47% of cases. Ligaments related to the nerve root were the most delicate and always attached to the intervertebral disc. Their mean length was 14.9 ± 1.8 mm.ConclusionsThe medial group of anterior MVLs are strong connective tissue bands dividing the anterior epidural space. The lateral group is more delicate, and in most cases, lateral MVLs lack annular attachment. MVLs could be an anatomical barrier for disc migration in particular cases.
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Pawel Szaro, Alexandra McGrath, Bogdan Ciszek, Mats Geijer
المصدر: European Journal of Radiology Open, Vol 9, Iss , Pp 100392- (2022)
مصطلحات موضوعية: Brachial plexus, Injury, Tumor, Compression, Neuropathy, Medical physics. Medical radiology. Nuclear medicine, R895-920
الوصف: For magnetic resonance imaging (MRI) of non-traumatic brachial plexus (BP) lesions, sequences with contrast injection should be considered in the differentiation between tumors, infection, postoperative conditions, and post-radiation changes. The most common non-traumatic inflammatory BP neuropathy is radiation neuropathy. T2-weighted images may help to distinguish neoplastic infiltration showing a high signal from radiation-induced neuropathy with fibrosis presenting a low signal.MRI findings in inflammatory BP neuropathy are usually absent or discrete. Diffuse edema of the BP localized mainly in the supraclavicular part of BP, with side-to-side differences, and shoulder muscle denervation may be found on MRI.BP infection is caused by direct infiltration from septic arthritis of the shoulder joint, spondylodiscitis, or lung empyema.MRI may help to narrow down the list of differential diagnoses of tumors. The most common tumor of BP is metastasis. The most common primary tumor of BP is neurofibroma, which is visible as fusiform thickening of a nerve. In its solitary state, it may be challenging to differentiate from a schwannoma.The most common MRI finding is a neurogenic variant of thoracic outlet syndrome with an asymmetry of signal and thickness of the BP with edema. In abduction, a loss of fat directly related to the BP may be seen.Diffusion tensor imaging is a promising novel MRI sequences; however, the small diameter of the nerves contributing to the BP and susceptibility to artifacts may be challenging in obtaining sufficiently high-quality images.
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Pawel Szaro, Mats Geijer, Bogdan Ciszek, Aleksandra McGrath
المصدر: European Journal of Radiology Open, Vol 9, Iss , Pp 100397- (2022)
مصطلحات موضوعية: Brachial plexus, Injury, Brachial plexus surgery, Magnetic resonance imaging, Anatomy, Treatment, Medical physics. Medical radiology. Nuclear medicine, R895-920
الوصف: The most common indications for magnetic resonance imaging (MRI) of the brachial plexus (BP) are traumatic injuries. The role of MRI of the BP has increased because of recent trends favoring earlier surgery. Determining preganglionic vs. postganglionic injury is essential, as different treatment strategies are required. Thus, MRI of the BP should be supplemented with cervical spine MRI to assess the intradural part of the spinal nerves, including highly T2-weighted techniques. Acute preganglionic injuries usually manifest as various combinations of post-traumatic pseudomeningocele, the absence of roots, deformity of nerve root sleeves, displacement of the spinal cord, hemorrhage in the spinal canal, presence of scars in the spinal canal, denervation of the back muscles, and syrinx. Spinal nerve root absence is more specific than pseudomeningocele on MRI. Acute postganglionic injuries can present as lesions in continuity or tears. The following signs indicate injury to the BP: side-to-side difference, swelling, partial, or total BP rupture. Injury patterns and localization are associated with the mechanism of trauma, which implies a significant role for MRI in the work-up of patients.The identification and description of traumatic lesions involving the brachial plexus need to be systematic and detailed. Using an appropriate MRI protocol, obtaining details about the injury, applying a systematic anatomical approach, and correlating imaging findings to relevant clinical data to make a correct diagnosis. Information about the presence or suspicion of root avulsion should always be provided.
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Aleksandra Kisilewicz, Pascal Madeleine, Zofia Ignasiak, Bogdan Ciszek, Adam Kawczynski, Ryan Godsk Larsen
المصدر: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
مصطلحات موضوعية: eccentric exercise, trapezius muscle, muscle stiffness, ultrasonography, myotonometry, Biotechnology, TP248.13-248.65
الوصف: In this study, we tested the hypotheses that unaccustomed eccentric exercise (ECC) would reduce the elastic modulus and dynamic stiffness of the upper trapezius muscle and that these changes would correlate with increases in muscle thickness, reflecting muscle edema. Shear wave elastography was used to measure elastic modulus, dynamic stiffness was assessed using myotonometry, and muscle thickness was measured using ultrasonography. All measurements were performed at four locations over the upper trapezius before and 24 h after a single bout of ECC. Fourteen healthy participants (11 males and 3 females; 23.2 ± 3.0 years; height 175.1 ± 10.4 cm; body mass 73.8 ± 11.3 kg) took part in the study. Overall, ECC resulted in decreased elastic modulus (from 45.8 ± 1.6 to 39.4 ± 1.2 kPa, p < 0.01) and dynamic muscle stiffness (from 369.0 ± 7.3 to 302.6 ± 6.0 N/m, p < 0.01). Additionally, ECC resulted in increased muscle thickness (from 6.9 ± 0.4 to 7.3 ± 0.4 mm, p < 0.01). Spatial changes (across the four locations) were found for elastic modulus, stiffness and thickness. No significant correlations were found between changes in measures of muscle stiffness, or between changes in stiffness and changes in thickness. In conclusion, the present pilot study showed that ECC altered biomechanical muscle properties, reflected by decreased elastic modulus and dynamic muscle stiffness 24 h after ECC.
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Justyna Niderla-Bielińska, Aneta Ścieżyńska, Aneta Moskalik, Ewa Jankowska-Steifer, Krzysztof Bartkowiak, Mateusz Bartkowiak, Ewelina Kiernozek, Anna Podgórska, Bogdan Ciszek, Barbara Majchrzak, Anna Ratajska
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 4, p 2197 (2021)
مصطلحات موضوعية: cardiac macrophages, miRNA, metabolic syndrome, myocardial remodeling, Biology (General), QH301-705.5, Chemistry, QD1-999
الوصف: Cardiac macrophages are known from various activities, therefore we presume that microRNAs (miRNAs) produced or released by macrophages in cardiac tissue have impact on myocardial remodeling in individuals with metabolic syndrome (MetS). We aim to assess the cardiac macrophage miRNA profile by selecting those miRNA molecules that potentially exhibit regulatory functions in MetS-related cardiac remodeling. Cardiac tissue macrophages from control and db/db mice (an animal model of MetS) were counted and sorted with flow cytometry, which yielded two populations: CD45+CD11b+CD64+Ly6Chi and CD45+CD11b+CD64+Ly6Clow. Total RNA was then isolated, and miRNA expression profiles were evaluated with Next Generation Sequencing. We successfully sequenced 1400 miRNAs in both macrophage populations: CD45+CD11b+CD64+Ly6Chi and CD45+CD11b+CD64+Ly6Clow. Among the 1400 miRNAs, about 150 showed different expression levels in control and db/db mice and between these two subpopulations. At least 15 miRNAs are possibly associated with MetS pathology in cardiac tissue due to direct or indirect regulation of the expression of miRNAs for proteins involved in angiogenesis, fibrosis, or inflammation. In this paper, for the first time we describe the miRNA transcription profile in two distinct macrophage populations in MetS-affected cardiac tissue. Although the results are preliminary, the presented data provide a foundation for further studies on intercellular cross-talk/molecular mechanism(s) involved in the regulation of MetS-related cardiac remodeling.
وصف الملف: electronic resource
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6دورية أكاديمية
المؤلفون: Łukasz Przepiórka, Przemysław Kunert, Paulina Juszyńska, Michał Zawadzki, Bogdan Ciszek, Mariusz Głowacki, Andrzej Marchel
المصدر: Frontiers in Neurology, Vol 9 (2018)
مصطلحات موضوعية: spinal dural arteriovenous fistula, tethered cord syndrome, lipoma, surgery, embolization, Neurology. Diseases of the nervous system, RC346-429
الوصف: Spinal dural arteriovenous fistula (SDAVF) is the most common vascular malformation of the spine in adults. However, the coincidence of tethered cord syndrome, lipoma, and SDAVF on the sacral level is exceptionally rare. We describe two patients, probably the fifth and sixth ever reported. The first was a 33 year-old female who underwent surgical cord de-tethering. Surprisingly, a sacral SDAVF was discovered intraoperatively, despite negative digital subtraction angiography (DSA). The second patient was a 30 year-old male with similar pathologies. After three failed embolizations, the fistula was surgically disconnected. Both patients recovered well. A review of patients with sacral SDAVF coexisting with spinal dysraphism, with an emphasis on the basis of symptoms was done. As a rule, in these coincident disorders, the SDAVF was the direct cause of increasing symptoms. Previous reports and our findings reveal that surgery might be superior to endovascular embolization for treating sacral SDAVFs with coexisting entities, because surgery offers a one-step treatment.
وصف الملف: electronic resource
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7دورية أكاديميةMusculus Palmaris Longus: Influence on Playing Capability of Keyboard Musicians – Preliminary Report
المؤلفون: Krzysztof Dąbrowski, Hanna Stankiewicz-Jóźwicka, Arkadiusz Kowalczyk, Michał Markuszewski, Bogdan Ciszek
المصدر: Frontiers in Psychology, Vol 9 (2018)
مصطلحات موضوعية: palmaris longus, wrist, hand, musician, keyboard, piano, Psychology, BF1-990
الوصف: Musculus Palmaris Longus (PL) is one of the most variable anatomical structures in the human body. Despite being biomechanically active, it is vastly considered to have no impact on the functionality of the upper extremity in the general population. The aim of this study is to examine the relation between playing capability of young musicians and morphology of Musculus PL and to compare it with the relation between manual capability of non-musicians and morphology of their Musculus PL. 42 forearms of 21 healthy individuals (11 musicians and 10 non-musicians) were subjected to Shaeffer’s test and ultrasound imaging and tested by dynamometer for hand grip strength and the first and fifth finger opposition before and after exertion. No difference in morphology pattern was observed between the groups. In the musicians, a substantial loss of a hand grip strength of the left hand compared to the right hand after exertion, regardless of lateralization, was observed. A disproportion in exhaustion of the musician’s hands with unilateral absence of PL was observed – the difference in grip strength between the dominant and non-dominant hand before and after exertion increased over eight times more than in the musicians with bilateral presence. There is no difference in PL morphology between either the musicians or non-musicians. Regardless of lateralization, the musician’s left hand in musicians seems weaker and therefore more prone to misuse related injuries. PL may play a role in musicians in balancing muscular exhaustion.
وصف الملف: electronic resource
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8دورية أكاديمية
المؤلفون: Paweł Szaro, Khaldun Ghali Gataa, Mateusz Polaczek, Bogdan Ciszek
المصدر: Applied Sciences, Vol 10, Iss 22, p 7972 (2020)
مصطلحات موضوعية: ankle, interconnections, fascia, flexor retinaculum, deltoid ligament, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
الوصف: This study aimed to prove the hypothesis that the medial structures of the ankle are interconnected through the flexor retinaculum’s projections. We conducted a retrospective re-evaluation of 132 MRI examinations of the ankle joint from 57 females and 75 males with an age range of 18–65 and a mean age of 35 years. The correlation between the presence of connections between the flexor retinaculum and the deltoid ligament, the spring ligament, the inferior extensor retinaculum, the paratenon, the fibulotalocalcaneal ligament, the fascia covering the abductor hallucis, and the flexor fibrous sheath were studied. The most common connections of the flexor retinaculum were to the deltoid ligament (97%), the fibulotalocalcaneal ligament (84.1%), and the flexor fibrous sheath (83.3%). Interconnection between the flexor retinaculum and the deltoid ligament correlated with the presence of connections between the flexor retinaculum and the inferior extensor retinaculum, the paratenon, and the spring ligament. Side difference was noticed in connections to the flexor fibrous sheath, the deltoid ligament, the fascia on the abductor hallucis, and the paratenon (p < 0.05). The flexor retinaculum formed a more complex anatomical unit with adjacent structures.
وصف الملف: electronic resource
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9دورية أكاديمية
المصدر: Applied Sciences, Vol 10, Iss 7, p 2616 (2020)
مصطلحات موضوعية: muscle stiffness, transcranial direct current stimulation, children, cerebral palsy, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
الوصف: Background: The aim of this study was to investigate the influence of transcranial direct current stimulation (tDCS) on the biceps brachii and flexor carpi radialis stiffness in children with cerebral palsy (CP). The authors also aimed to verify the relationship between spasticity and muscle stiffness. Methods: Twelve children with CP (mean ± SD; age, 8 ± 1.3 years; height, 118.7 ± 4.1 cm; weight, 23.0 ± 2.2 kg) were involved in the study. Muscle stiffness was estimated using a MyotonPRO device in a MultiScan pattern of five measurements. Simultaneously, the tDCS stimulation was performed. Spasticity was assessed by a neurologist using the Ashworth Scale. Results: Stiffness of the flexor carpi radialis muscle decreased significantly after tDCS therapy (p = 0.04). There was no significant change in stiffness of the biceps brachii. For all participants, the Spearman rank correlation showed statistically significant and positive relationships between muscle stiffness and the Ashworth Scale (p = 0.04). Conclusions: Transcranial direct current stimulation has a decreasing effect on stiffness and spasticity of the flexor carpi radialis in children with CP. The MyotonPRO device provides objective data and correlates with spasticity measurements.
وصف الملف: electronic resource
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10دورية أكاديمية
المؤلفون: Iulian Komarnitki, Jacek Tomczyk, Bogdan Ciszek, Marta Zalewska
المصدر: PLoS ONE, Vol 10, Iss 4, p e0123120 (2015)
الوصف: The topography of the auriculotemporal nerve (ATN) root system is the main criterion of this nerve classification. Previous publications indicate that ATN may have between one and five roots. Most common is a one- or two-root variant of the nerve structure. The problem of many publications is the inconsistency of nomenclature which concerns the terms "roots", "connecting branches", or "branches" that are used to identify the same structures. This study was performed on 80 specimens (40 adults and 40 fetuses) to propose a classification based on: (i) the number of roots, (ii) way of root division, and (iii) configuration of interradicular fibers that form the ATN trunk. This new classification is a remedy for inconsistency of nomenclature of ATN in the infratemporal fossa. This classification system has proven beneficial when organizing all ATN variants described in previous studies and could become a helpful tool for surgeons and dentists. Examination of ATN from the infratemporal fossa of fetuses (the youngest was at 18 weeks gestational age) showed that, at that stage, the nerve is fully developed.
وصف الملف: electronic resource
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