المؤلفون: Li J, Zhong G, Wang K, Kang W, Wei W

المصدر: Cancer Management and Research, Vol Volume 13, Pp 4463-4471 (2021)

مصطلحات موضوعية: breast cancer；cone-beam breast computed tomography, cbbct；tumor-to-gland volume ratio；tumor-to-breast volume ratio；breast-conserving surgery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Jiawei Li,1 Guobin Zhong,1 Keqiong Wang,1 Wei Kang,2 Wei Wei1 1Department of Breast Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Dominant Cultivation Discipline of Guangxi Medical University Cancer Hospital (Medical Imaging Department), Guangxi Key Clinical Specialty (Medical Imaging Department), Nanning, Guangxi, People’s Republic of ChinaCorrespondence: Wei Wei; Wei Kang Email 605347565@qq.com; xuanbingche0313@126.comBackground: Breast-conserving surgery plus postoperative radiotherapy is the standard surgical treatment mode for early breast cancer. Currently, there are no clear predictive indicators to determine whether a patient can choose breast-conserving surgery, which mainly depends on the surgeon’s clinical experience and subjective judgment. Cone-beam breast computed tomography (CBBCT) reconstructs the breast 3D image from three mutually perpendicular angles, helping surgeons to locate and accurately measure the volume of the tumor, mammary gland, and breast. We used CBBCT to retrospectively measure the tumor-to-gland volume ratio and tumor-to-breast volume ratio in breast cancer cases. Then, we analyzed the correlation between the surgical methods and ratios in breast cancer patients.Methods: We collected 100 patients undergoing breast-conserving surgery as the study group, and 100 patients undergoing mastectomy as the control group. All patients chose the surgical approach after comprehensive consideration of examination results and assessment of patient condition. Patients underwent CBBCT examination before surgery. We retrospectively measured the volume of tumor, mammary glands and breast, then calculated tumor-to-gland and tumor-to-breast volume ratios.Results: Tumor volume and the ratios of the two groups statistically differed (P < 0.001), while the mammary gland and breast volume did not (P > 0.05). The average tumor-to-gland volume ratio was 4.32% in the study group and 10.74% in the control group, and the average tumor-to-breast volume ratio was 0.74% in the study group and 1.36% in the control group. In breast-conserving surgery, the 95% reference range of tumor-to-gland ratio is (0, 12.90%), and the 95% reference range of tumor-to-breast ratio is (0, 2.17%).Conclusion: The tumor-to-gland volume ratio and tumor-to-breast volume ratio measured using CBBCT are correlated with the choice of surgical methods (breast-conserving surgery or mastectomy) for breast cancer patients. This can be used as possible predictor of breast-conserving surgery to help surgeons.Keywords: breast cancer, cone-beam breast computed tomography, CBBCT, tumor-to-gland volume ratio, tumor-to-breast volume ratio, breast-conserving surgery

وصف الملف: electronic resource

Relation: https://www.dovepress.com/tumor-to-gland-volume-ratio-versus-tumor-to-breast-ratio-as-measured-o-peer-reviewed-fulltext-article-CMAR; https://doaj.org/toc/1179-1322

URL الوصول: https://doaj.org/article/55f46c41b662491facaad235557fc627

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المؤلفون: Avice M. O'Connell, Thomas J. Marini, Daniel T. Kawakyu-O'Connor

المصدر: Journal of Clinical Medicine, Vol 10, Iss 21, p 5135 (2021)

مصطلحات موضوعية: breast cancer, cone-beam breast computed tomography (CBBCT), mammography, Medicine

الوصف: It is time to reconsider how we image the breast. Although the breast is a 3D structure, we have traditionally used 2D mammography to perform screening and diagnostic imaging. Mammography has been continuously modified and improved, most recently with tomosynthesis and contrast mammography, but it is still using modifications of compression 2D mammography. It is time to consider 3D imaging for this 3D structure. Cone-beam breast computed tomography (CBBCT) is a revolutionary modality that will assist in overcoming the limitations of current imaging for dense breast tissue and overlapping structures. It also allows easy administration of contrast material for functional imaging. With a radiation dose on par with diagnostic mammography, rapid 10 s acquisition, no breast compression, and true high-resolution isotropic imaging, CBBCT has the potential to usher in a new era in breast imaging. These advantages could translate into lower morbidity and mortality from breast cancer.

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2077-0383/10/21/5135; https://doaj.org/toc/2077-0383

URL الوصول: https://doaj.org/article/eb61962b78a04101be22589e4983fa78

المؤلفون: Jiawei Li, Wei Wei, Guobin Zhong, Wei Kang, Keqiong Wang

المصدر: Cancer Management and Research
Cancer Management and Research, Vol Volume 13, Pp 4463-4471 (2021)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Mammary gland, Postoperative radiotherapy, Reference range, Surgical methods, 03 medical and health sciences, breast cancer, 0302 clinical medicine, Breast cancer, medicine, Breast-conserving surgery, cbbct；tumor-to-gland volume ratio；tumor-to-breast volume ratio；breast-conserving surgery, skin and connective tissue diseases, RC254-282, Original Research, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, tumor-to-gland volume ratio, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Oncology, Surface-area-to-volume ratio, Cancer Management and Research, 030220 oncology & carcinogenesis, CBBCT, cone-beam breast computed tomography, Radiology, breast-conserving surgery, tumor-to-breast volume ratio, business, breast cancer；cone-beam breast computed tomography, Mastectomy

الوصف: Jiawei Li,1 Guobin Zhong,1 Keqiong Wang,1 Wei Kang,2 Wei Wei1 1Department of Breast Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Dominant Cultivation Discipline of Guangxi Medical University Cancer Hospital (Medical Imaging Department), Guangxi Key Clinical Specialty (Medical Imaging Department), Nanning, Guangxi, People’s Republic of ChinaCorrespondence: Wei Wei; Wei Kang Email 605347565@qq.com; xuanbingche0313@126.comBackground: Breast-conserving surgery plus postoperative radiotherapy is the standard surgical treatment mode for early breast cancer. Currently, there are no clear predictive indicators to determine whether a patient can choose breast-conserving surgery, which mainly depends on the surgeon’s clinical experience and subjective judgment. Cone-beam breast computed tomography (CBBCT) reconstructs the breast 3D image from three mutually perpendicular angles, helping surgeons to locate and accurately measure the volume of the tumor, mammary gland, and breast. We used CBBCT to retrospectively measure the tumor-to-gland volume ratio and tumor-to-breast volume ratio in breast cancer cases. Then, we analyzed the correlation between the surgical methods and ratios in breast cancer patients.Methods: We collected 100 patients undergoing breast-conserving surgery as the study group, and 100 patients undergoing mastectomy as the control group. All patients chose the surgical approach after comprehensive consideration of examination results and assessment of patient condition. Patients underwent CBBCT examination before surgery. We retrospectively measured the volume of tumor, mammary glands and breast, then calculated tumor-to-gland and tumor-to-breast volume ratios.Results: Tumor volume and the ratios of the two groups statistically differed (P < 0.001), while the mammary gland and breast volume did not (P > 0.05). The average tumor-to-gland volume ratio was 4.32% in the study group and 10.74% in the control group, and the average tumor-to-breast volume ratio was 0.74% in the study group and 1.36% in the control group. In breast-conserving surgery, the 95% reference range of tumor-to-gland ratio is (0, 12.90%), and the 95% reference range of tumor-to-breast ratio is (0, 2.17%).Conclusion: The tumor-to-gland volume ratio and tumor-to-breast volume ratio measured using CBBCT are correlated with the choice of surgical methods (breast-conserving surgery or mastectomy) for breast cancer patients. This can be used as possible predictor of breast-conserving surgery to help surgeons.Keywords: breast cancer, cone-beam breast computed tomography, CBBCT, tumor-to-gland volume ratio, tumor-to-breast volume ratio, breast-conserving surgery

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a091805feaf750f5b5d2cf05ad70b1
https://doi.org/10.2147/cmar.s312288

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المؤلفون: Daniel Kawakyu-O’Connor, Thomas J. Marini, Avice M O'Connell

المصدر: Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 5135, p 5135 (2021)

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Breast imaging, mammography, Computed tomography, General Medicine, Review, medicine.disease, Tomosynthesis, Functional imaging, Breast cancer, breast cancer, cone-beam breast computed tomography (CBBCT), medicine, Medical imaging, Mammography, Medicine, Radiology, Diagnostic Mammography, business, skin and connective tissue diseases

الوصف: It is time to reconsider how we image the breast. Although the breast is a 3D structure, we have traditionally used 2D mammography to perform screening and diagnostic imaging. Mammography has been continuously modified and improved, most recently with tomosynthesis and contrast mammography, but it is still using modifications of compression 2D mammography. It is time to consider 3D imaging for this 3D structure. Cone-beam breast computed tomography (CBBCT) is a revolutionary modality that will assist in overcoming the limitations of current imaging for dense breast tissue and overlapping structures. It also allows easy administration of contrast material for functional imaging. With a radiation dose on par with diagnostic mammography, rapid 10 s acquisition, no breast compression, and true high-resolution isotropic imaging, CBBCT has the potential to usher in a new era in breast imaging. These advantages could translate into lower morbidity and mortality from breast cancer.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3fb339fa9ba3c5dade6d8f815bef6a
http://europepmc.org/articles/PMC8584471

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