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1دورية أكاديمية
المؤلفون: Zhiqing Zhang, Hua Liu, Shude Ji, Jiaqi Zhang, Chen Jin, Lin Ma, Qi Song
المصدر: Journal of Materials Research and Technology, Vol 30, Iss , Pp 5096-5108 (2024)
مصطلحات موضوعية: Impacting flow friction stir lap welding, 7B04 aluminum alloys, Welding tool with X-shape reverse-threaded pin, Lap interface morphology, Tensile shear load, Mining engineering. Metallurgy, TN1-997
الوصف: Avoiding the upward-bending hook is a highly pressing and challenging task in the field of similar aluminum alloys friction stir lap welding (FSLW). To enhance formation quality and then obtain the welded lap joint with high tensile shear load, a novel impacting flow FSLW (IF-FSLW) process based on the X-shape reverse-threaded pin was proposed in this study. Three welding tools with different tool geometry parameters were developed to analyze how the locations of the materials accumulated zone (MAZ) influenced the joint formation and the joint loading capacity, and 7B04 aluminum alloys were chosen as research subject. Results showed that the horizontally-impacting and vertically-impacting effects of MAZ on and above the original lap interface made the hook respectively present the forky structure at the end and the downward-bending morphology, and the horizontally-impacting effect of MAZ made the stir zone (SZ) have a protruding morphology near the MAZ. Under the tensile fracture mode, the IF-FSLW joint under configuration A had a greatly heightened tensile shear load under the combined actions of the downward-bending hook and the enlarged SZ. The tensile shear load of IF-FSLW joint reached 8.62 kN/mm under the reasonable combination of tool geometry parameters and welding process parameters. The IF-FSLW process by the X-shape reverse-threaded pin provides an effective way to obtain a superb-strength lap joint of aluminum alloys.
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: ZHANG Yuan-quan, LV Jian-hua, BAI Chun-qi, HAN Zhi-qiang, ZHANG Feng, CHEN Jin-shen
المصدر: Liang you shipin ke-ji, Vol 32, Iss 3, Pp 195-200 (2024)
مصطلحات موضوعية: stored grain insects, insect-proof packaging, penetration, packaging material, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641
الوصف: In order to clarify the controlling effect of different packaging materials on common storage pests, the penetration and survival of 7 kinds of high density polyethylene films with different concentrations of deltamethrin by the larvae of 3 common species of stored grain pests (Tribolium castaneum (Herbst), Tribolium confusum Duval and Lasioderma serricorne (Fabricius)) were investigated after being treated by two penetration methods for different times at 27~29 ℃ and 70%~80% RH. The results showed that all the tested new insect-proof films had certain insect resistance capabilities, which were different based on species of stored grain insects. In addition, the insect resistance capability of the 6 kinds of new films containing chemicals was higher than that of the control films after 9 days of treatment, and the anti-penetration rate of 1% A (HDPE particle containing 5% deltamethrin by mass) film, 3% A film, 1% B (HDPE particle containing 5% deltamethrin and 2% isoethers by mass) film and 3% B film was 100% under two penetration modes. The survival rate of all three species larvae decreased with increasing treatment time. After 9 days of parallel penetration treatment, the survival rate of three species of larvae on 3%B film was significantly lower than that of other films, and the survival rate of L. serricorne larvae reduced to 10% at the lowest. According to the penetration resistance and larvae survival rate of the test insects on the films, 3% B film had the best insect control effectiveness.
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: HE Xiao-ying, ZHU Yan-guang, WANG Ping-dong, CHEN Jin-ying
المصدر: Liang you shipin ke-ji, Vol 32, Iss 3, Pp 162-169 (2024)
مصطلحات موضوعية: zearalenone, graphitic carbon nitride, photocatalytic degradation, thermal cracking, photocatalyic materials, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641
الوصف: A semiconductor nanomaterial was prepared and its degradation efficiency on zearalenone (ZEN) was investigated. The photocatalytic material, graphitic carbon nitride (g-C3N4), was synthesized by the conventional thermal cracking method, and its structure was analyzed by (X-ray diffraction) XRD, Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The photocatalytic degradation experiments showed that g-C3N4 induced photocatalytic effects under ultraviolet light (254 nm, including 185 nm), releasing reactive oxygen radicals to degrade ZEN. The experimental conditions for the photocatalytic degradation of ZEN were explored. The results showed that the degradation rate of ZEN was 96.0% when the mass of the photocatalytic material , the wavelength of the UV lamp, the initial concentration and the irradiation time were 20 mg, 254 nm (50 W), 0.5 μg/mL and 60 min, respectively. Meanwhile, the experimental conditions for the photocatalytic degradation of ZEN powder samples were optimized. The results showed that the degradation rate of ZEN was 80.0% when the mass of the photocatalytic material, the wavelength of the UV lamp, and the irradiation time were 800 mg, 254 nm (50 W) and 50 min, respectively. The results could provide a theoretical reference and practical basis for the photocatalytic degradation of ZEN.
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Wang Hao, Zhao Wei, Wang Daorong, Chen Jin
المصدر: Open Medicine, Vol 19, Iss 1, Pp 1-15 (2024)
مصطلحات موضوعية: ano6 (tmem16f), gastrointestinal stromal tumor, ferroptosis, Medicine
الوصف: Herein, we elucidate the potential role of ANO6 (TMEM16F) in gastrointestinal stromal tumors (GISTs). ANO6 expression in GIST and adjacent normal tissues was determined using reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blotting. Cell proliferation, apoptosis, and pyroptosis were examined utilizing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, terminal deoxynucleotidyl transferase dUTP Nick-End Labeling staining, and flow cytometry. In addition, the total iron and Fe2+ levels were assessed. IL-18 and IL-1β levels were also evaluated. Lipid reactive oxygen species (ROS), cystine (Cys), glutathione (GSH), and glutathione peroxidase 4 (GPX4) levels were evaluated using appropriate kits. Ferroptotic markers, including Ptgs2, Chac1, SLC7A11, and SLC3A2, were analyzed by RT-qPCR, western blotting, and immunohistochemistry. ANO6 expression decreased in GIST tissues. ANO6-plasmid inhibits proliferation, induces apoptosis, and promotes pyroptosis in GIST-T1 and GIST-T1 IR cells. The ANO6-plasmid induced ferroptosis, as confirmed by enhanced lipid ROS levels, increased intracellular concentrations of total iron and Fe2+, promoted Ptgs2 and Chac1 expression, reduced Cys, GSH, and GPX4 levels, and downregulated SLC7A11 and SLC3A2 expression after in vitro and in vivo treatment with ANO6-plasmid. Moreover, the ANO6-plasmid inhibited GIST growth in vivo. Therefore, ANO6 may be a promising therapeutic target for blocking the development of GIST via the induction of apoptosis, pyroptosis, and ferroptosis.
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2391-5463
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5دورية أكاديمية
المؤلفون: HE Xiao-ying, HE Yan, GU Yu-xi, WANG Jin, CHEN Jin-ying
المصدر: Liang you shipin ke-ji, Vol 32, Iss 2, Pp 136-144 (2024)
مصطلحات موضوعية: fusarium oxysporum, virulence, mycotoxin, chlorine dioxide, ozone, fumigation, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641
الوصف: Fusarium infection of wheat can lead to scab, mycotoxin contamination and yield reduction. Fusarium is a serious threat to food security. In this study, the Fusarium strains in wheat were isolated and identified. The three strains N1, N2 and N3 belonged to Fusarium graminearum, Fusarium asiaticum and Fusarium culmatum, respectively. The production of zearalenone, vomitoxin and fumonisin by the three strains was analyzed by toxin-producing gene detection and mycotoxin detection. The results showed that N1 and N3 could produce zearalenone and vomitoxin, but did not produce fumonisin, while N2 did not produce these three toxins. In this study, ozone and chlorine dioxide were further used for gas fumigation to explore the effect of gas fumigation on the three strains isolated. By observing the spore morphology, mycelium length and mycelium morphology, the results showed that chlorine dioxide fumigation could effectively inhibit the growth of mycelium and spore germination, while ozone could only inhibit spore germination and had no obvious inhibitory effect on the growth of mycelium.
وصف الملف: electronic resource
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6دورية أكاديمية
المؤلفون: Mengyu He, Chen Jin, Cheng Li, Zeyi Cai, Dongdong Peng, Xiang Huang, Jun Wang, Yuanning Zhai, Hengnian Qi, Chu Zhang
المصدر: Food Chemistry: X, Vol 22, Iss , Pp 101481- (2024)
مصطلحات موضوعية: Hyperspectral imaging, Spinach, Pigments, Multi-task regression, Convolutional neural networks, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456
الوصف: Rapid and accurate determination of pigment content is important for quality inspection of spinach leaves during storage. This study aimed to use hyperspectral imaging at two spectral ranges (visible/near-infrared, VNIR: 400–1000 nm; NIR: 900–1700 nm) to simultaneously determine the pigment (chlorophyll a, chlorophyll b, total chlorophyll, and carotenoids) content in spinach stored at different durations and conditions (unpackaged and packaged). Partial least squares (PLS), back propagation neural network (BPNN) and convolutional neural network (CNN) were used to establish single-task and multi-task regression models. Single-task CNN (STCNN) models and multi-task CNN (MTCNN) models obtained better performances than the other models. The models using VNIR spectra were superior to those using NIR spectra. The overall results indicated that hyperspectral imaging with multi-task learning could predict the quality attributes of spinach simultaneously for spinach quality inspection under various storage conditions. This research will guide food quality inspection by simultaneously inspecting multiple quality attributes.
وصف الملف: electronic resource
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7دورية أكاديمية
المؤلفون: Chen Jin, Zheng Lu, Zhou Wenwen, Liu Min, Gao Yuyu, Xie Jiaqiang
المصدر: e-Polymers, Vol 23, Iss 1, Pp 1800618-72 (2023)
مصطلحات موضوعية: 3d printing photosensitive resin, silicone, epoxy acrylate, mechanical properties, thermal stability, Polymers and polymer manufacture, TP1080-1185
الوصف: Herein, the performance of silicone-modified 3D printing photosensitive resin was examined. Bisphenol-A epoxy acrylate (EA) was used as the substrate and isophorone diisocyanate, hydroxy-silicone oil, and hydroxyethyl acrylate were used as the raw materials. A silicone intermediate was synthesized to modify the substrate to prepare the 3D printing photosensitive material. The as-synthesized materials were characterized using Fourier transform infrared spectroscopy and scanning electron microscopy. The tensile fracture morphology was also analyzed. The effects of the addition of silicone intermediates on the mechanical properties, thermal stability, and shrinkage of the prepared 3D printing photosensitive resins were investigated. The results showed that an organosilicone group was successfully introduced into the side chain of EA. When the ratio of n(silicone):n(EA) is 0.3:1, the material has a high impact strength of 19.4 kJ·m−2, which is 32.8% higher than that of the pure resin; in addition, the elongation at break is 8.65% (compared to 6.56% of the pure resin). The maximum thermal weight loss temperature is 430.33°C, which is 6°C higher than that of the pure resin.
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1618-7229
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8دورية أكاديمية
المؤلفون: Chen Jin, Kaiwei Wang, Yilong Ren, Yi Li, Zhanwei Wang, Liming Cheng, Ning Xie
المصدر: MedComm, Vol 5, Iss 4, Pp n/a-n/a (2024)
مصطلحات موضوعية: decompression, durotomy, functional recovery, secondary injuries, Spinal cord injury, Medicine
الوصف: Abstract Currently, there is a lack of effective treatments for spinal cord injury (SCI), a debilitating medical condition associated with enduring paralysis and irreversible neuronal damage. Extradural decompression of osseous as well as soft tissue components has historically been the principal objective of surgical procedures. Nevertheless, this particular surgical procedure fails to tackle the intradural compressive alterations that contribute to secondary SCI. Here, we propose an early intrathecal decompression strategy and evaluate its role on function outcome, tissue sparing, inflammation, and tissue stiffness after SCI. Durotomy surgery significantly promoted recovery of hindlimb locomotor function in an open‐field test. Radiological analysis suggested that lesion size and tissue edema were significantly reduced in animals that received durotomy. Relative to the group with laminectomy alone, the animals treated with a durotomy had decreased cavitation, scar formation, and inflammatory responses at 4 weeks after SCI. An examination of the mechanical properties revealed that durotomy facilitated an expeditious restoration of the injured tissue's elastic rigidity. In general, early decompressive durotomy could serve as a significant strategy to mitigate the impairments caused by secondary injury and establish a more conducive microenvironment for prospective cellular or biomaterial transplantation.
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2688-2663
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9دورية أكاديمية
المؤلفون: Xueping Li, Jiarui Zhou, Xingmei Liu, Chen Jin, Le Liu, Hongmin Sun, Qian Wang, Qiushi Wang, Ruiying Liu, Xiaoyu Zheng, Yutao Liu, Yu Pang
المصدر: Cell Reports, Vol 43, Iss 4, Pp 114051- (2024)
مصطلحات موضوعية: CP: Microbiology, CP: Cell biology, Biology (General), QH301-705.5
الوصف: Summary: Uropathogenic Escherichia coli (UPEC) is the most common causative agent of urinary tract infection (UTI). UPEC invades bladder epithelial cells (BECs) via fusiform vesicles, escapes into the cytosol, and establishes biofilm-like intracellular bacterial communities (IBCs). Nucleoside-diphosphate kinase (NDK) is secreted by pathogenic bacteria to enhance virulence. However, whether NDK is involved in UPEC pathogenesis remains unclear. Here, we find that the lack of ndk impairs the colonization of UPEC CFT073 in mouse bladders and kidneys owing to the impaired ability of UPEC to form IBCs. Furthermore, we demonstrate that NDK inhibits caspase-1-dependent pyroptosis by consuming extracellular ATP, preventing superficial BEC exfoliation, and promoting IBC formation. UPEC utilizes the reactive oxygen species (ROS) sensor OxyR to indirectly activate the regulator integration host factor, which then directly activates ndk expression in response to intracellular ROS. Here, we reveal a signaling transduction pathway that UPEC employs to inhibit superficial BEC exfoliation, thus facilitating acute UTI.
وصف الملف: electronic resource
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10دورية أكاديمية
المؤلفون: Yu Qian, Xiaohe Wang, Xianhong Huang, Jinwen Li, Chen Jin, Jie Chen, MengYi Sha
المصدر: Frontiers in Psychology, Vol 15 (2024)
مصطلحات موضوعية: patient satisfaction, bounded rationality theory, psychological factors, structural equation model, suppressive effect, Psychology, BF1-990
الوصف: IntroductionPatient satisfaction is a crucial metric to gauge the quality of medical services, but the psychological factors influencing patient satisfaction remain insufficiently explored.MethodsThis study examines these psychological factors by applying the theory of bounded rationality to 1,442 inpatients in Hangzhou, China, whose data were collected using a questionnaire. One-way ANOVA, correlation analysis, and hierarchical regression were used to analyze patient satisfaction and its associated factors. Additionally, the path analysis of the structural equation model revealed the mechanisms behind the key psychological factors that influenced patient satisfaction.ResultsMedical risk perception, the social cognition of the medical environment, and social desirability bias had significant positive impacts on patient satisfaction. By contrast, negative emotions had a significant negative impact on patient satisfaction. Notably, patients’ negative emotions had both a suppressive effect and a positive moderating effect on the relationship between medical risk perception and patient satisfaction. Similarly, social desirability bias had a suppressive effect on the correlation between the social cognition of the medical environment and patient satisfaction, albeit with a negative moderating effect.DiscussionThese results suggest that when evaluating and improving patient satisfaction, accounting only for the factors that directly influence medical service quality is insufficient, as the indirect and moderating effects of patients’ negative emotions and the social cognition of the medical environment must also be considered. Medical service providers should thus address patients’ negative emotions, establish good doctor–patient relationships, optimize service environments, provide managers with medical risk education and training on negative emotions, and prioritize patient-centered care. Additionally, the government and relevant health departments should optimize medical policies, enhance fairness and accessibility, and create a positive social cognitive environment through public education and awareness campaigns.
وصف الملف: electronic resource
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