المؤلفون: Thomas Messervey, Marco Calderoni, Angel Font, Mikel Borras, Ray Sterling, David Martin, Zia Lennard

المصدر: Proceedings, Vol 2, Iss 15, p 557 (2018)

مصطلحات موضوعية: enhanced geothermal systems, hybrid ground-source heat pumps, shallow, General Works

الوصف: GEOFIT, “Deployment of novel GEOthermal systems, technologies and tools for energy efficient building retrofitting,” is a recently launched 4-year H2020 project funded by the Innovation and Networks Executive Agency (INEA) under the call topic LCE-17-2017: Easier to install and more efficient geothermal systems for retrofitting buildings. GEOFIT is a part of INEA’s Energy Portfolio Low Carbon Economy (LCE), Renewable Energy Technologies (RET) and brings together 24 partners from 10 European countries to work on the development of novel and smart shallow geothermal systems. This paper introduces the project.

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2504-3900/2/15/557; https://doaj.org/toc/2504-3900

URL الوصول: https://doaj.org/article/7633a9141be64e44a217464c6b6f3783

المؤلفون: Iqbal, Hafsa, Al-Kaff, Abdulla, Marin, Pablo, Marcenaro, Lucio, Gomez, David Martin, Regazzoni, Carlo

المصدر: 2021 IEEE International Intelligent Transportation Systems Conference (ITSC) Intelligent Transportation Systems Conference (ITSC),2021 IEEE International. :2788-2793 Sep, 2021

Relation: 2021 IEEE International Intelligent Transportation Systems Conference (ITSC)

المؤلفون: Velázquez, David Martín, De Biasio, Davide, Lust, Dieter

مصطلحات موضوعية: High Energy Physics - Theory

الوصف: In the following work, an attempt to conciliate the Ricci flow conjecture and the Cobordism conjecture, stated as refinements of the Swampland distance conjecture and of the No global symmetries conjecture respectively, is presented. This is done by starting from a suitable manifold with trivial cobordism class, applying surgery techniques to Ricci flow singularities and trivialising the cobordism class of one of the resulting connected components via the introduction of appropriate defects. The specific example of $\Omega^{SO}_4$ is studied in detail. A connection between the process of blowing up a point of a manifold and that of taking the connected sum of such with $\mathbb{CP}^n$ is explored. Hence, the problem of studying the Ricci flow of a $K3$ whose cobordism class is trivialised by the addition of $16$ copies of $\mathbb{CP}^2$ is tackled by applying both the techniques developed in the previous sections and the classification of singularities in terms of ADE groups.
Comment: 52 pages, 2 figures

URL الوصول: http://arxiv.org/abs/2209.10297

المؤلفون: Kristy Martin, Walter Staiano, Paolo Menaspà, Tom Hennessey, Samuele Marcora, Richard Keegan, Kevin G Thompson, David Martin, Shona Halson, Ben Rattray

المصدر: PLoS ONE, Vol 11, Iss 7, p e0159907 (2016)

مصطلحات موضوعية: Medicine, Science

الوصف: Given the important role of the brain in regulating endurance performance, this comparative study sought to determine whether professional road cyclists have superior inhibitory control and resistance to mental fatigue compared to recreational road cyclists.After preliminary testing and familiarization, eleven professional and nine recreational road cyclists visited the lab on two occasions to complete a modified incongruent colour-word Stroop task (a cognitive task requiring inhibitory control) for 30 min (mental exertion condition), or an easy cognitive task for 10 min (control condition) in a randomized, counterbalanced cross-over order. After each cognitive task, participants completed a 20-min time trial on a cycle ergometer. During the time trial, heart rate, blood lactate concentration, and rating of perceived exertion (RPE) were recorded.The professional cyclists completed more correct responses during the Stroop task than the recreational cyclists (705±68 vs 576±74, p = 0.001). During the time trial, the recreational cyclists produced a lower mean power output in the mental exertion condition compared to the control condition (216±33 vs 226±25 W, p = 0.014). There was no difference between conditions for the professional cyclists (323±42 vs 326±35 W, p = 0.502). Heart rate, blood lactate concentration, and RPE were not significantly different between the mental exertion and control conditions in both groups.The professional cyclists exhibited superior performance during the Stroop task which is indicative of stronger inhibitory control than the recreational cyclists. The professional cyclists also displayed a greater resistance to the negative effects of mental fatigue as demonstrated by no significant differences in perception of effort and time trial performance between the mental exertion and control conditions. These findings suggest that inhibitory control and resistance to mental fatigue may contribute to successful road cycling performance. These psychobiological characteristics may be either genetic and/or developed through the training and lifestyle of professional road cyclists.

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4956323?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/aaabd40ac7c041cda825f8045dfde080

المؤلفون: Mélanie Métrich, Fortesa Mehmeti, Helene Feliciano, David Martin, Julien Regamey, Piergiorgio Tozzi, Philippe Meyer, Roger Hullin, Swiss Transplant Cohort Study

المصدر: PLoS ONE, Vol 11, Iss 9, p e0163475 (2016)

مصطلحات موضوعية: Medicine, Science

الوصف: Maximal exercise capacity after heart transplantion (HTx) is reduced to the 50-70% level of healthy controls when assessed by cardiopulmonary exercise testing (CPET) despite of normal left ventricular function of the donor heart. This study investigates the role of donor heart β1 and β2- adrenergic receptor (AR) polymorphisms for maximal exercise capacity after orthotopic HTx.CPET measured peak VO2 as outcome parameter for maximal exercise in HTx recipients ≥9 months and ≤4 years post-transplant (n = 41; mean peak VO2: 57±15% of predicted value). Donor hearts were genotyped for polymorphisms of the β1-AR (Ser49Gly, Arg389Gly) and the β2-AR (Arg16Gly, Gln27Glu). Circumferential shortening of the left ventricle was measured using magnetic resonance based CSPAMM tagging.Peak VO2 was higher in donor hearts expressing the β1-Ser49Ser alleles when compared with β1-Gly49 carriers (60±15% vs. 47±10% of the predicted value; p = 0.015), and by trend in cardiac allografts with the β1-AR Gly389Gly vs. β1-Arg389 (61±15% vs. 54±14%, p = 0.093). Peak VO2 was highest for the haplotype Ser49Ser-Gly389, and decreased progressively for Ser49Ser-Arg389Arg > 49Gly-389Gly > 49Gly-Arg389Arg (adjusted R2 = 0.56, p = 0.003). Peak VO2 was not different for the tested β2-AR polymorphisms. Independent predictors of peak VO2 (adjusted R2 = 0.55) were β1-AR Ser49Gly SNP (p = 0.005), heart rate increase (p = 0.016), and peak systolic blood pressure (p = 0.031). Left ventricular (LV) motion kinetics as measured by cardiac MRI CSPAMM tagging at rest was not different between carriers and non-carriers of the β1-AR Gly49allele.Similar LV cardiac motion kinetics at rest in donor hearts carrying either β1-AR Gly49 or β1-Ser49Ser variant suggests exercise-induced desensitization and down-regulation of the β1-AR Gly49 variant as relevant pathomechanism for reduced peak VO2 in β1-AR Gly49 carriers.

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5036840?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/42d4d21d1c01435fae48244cf217484d

المؤلفون: Magliocca, Pierpaolo, Herold, David Martin M., Canestrino, Rossella, Temperini, Valerio, Albino, Vito

المصدر: Journal of Knowledge Management, 2022, Vol. 27, Issue 10, pp. 2625-2641.

URL الوصول: http://www.emeraldinsight.com/doi/10.1108/JKM-07-2022-0593

المؤلفون: Ferraro, Sebastián J., de Diego, David Martín, de Almagro, Rodrigo Takuro Sato Martín

مصطلحات موضوعية: Mathematics - Optimization and Control, Mathematics - Numerical Analysis, 70-08, 70-10, 70G45, 70Hxx, 70Q05, 93-XX, 93C10, 49-XX, 49Mxx, 49M20, 65L10, 65L20

الوصف: Discrete variational methods show excellent performance in numerical simulations of different mechanical systems. In this paper, we introduce an iterative procedure for the solution of discrete variational equations for boundary value problems. More concretely, we explore a parallelization strategy that leverages the capabilities of multicore CPUs and GPUs (graphics cards). We study this parallel method for higher-order Lagrangian systems, which appear in fully-actuated problems and beyond. The most important part of the paper is devoted to a precise study of different convergence conditions for these methods. We illustrate their excellent behavior in some interesting examples, namely Zermelo's navigation problem, a fuel-optimal navigation problem, interpolation problems or in a fuel optimization problem for a controlled 4-body problem in astrodynamics showing the potential of our method.

URL الوصول: http://arxiv.org/abs/2206.08968

المؤلفون: Anne Laure Dalle Ave, David Martin Shaw

المصدر: Swiss Medical Weekly, Vol 145, Iss 1516 (2015)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://www.smw.ch/index.php/smw/article/view/2021; https://doaj.org/toc/1424-3997

URL الوصول: https://doaj.org/article/8e6919c985a14467886293dfbed96442

المؤلفون: Rajith Mendis, Caran Cheung, David Martin

المصدر: Surgery Research and Practice, Vol 2015 (2015)

مصطلحات موضوعية: Surgery, RD1-811

الوصف: Background. Despite advances in surgical repair of hiatus hernias, there remains a high radiological recurrence rate. We performed a novel technique incorporating bilateral oesophageal fixation and evaluated outcomes, principally symptom improvement and hernia recurrence. Methods. A retrospective study was performed on a prospective database of patients undergoing hiatus hernia repair with bilateral oesophageal fixation. Retrospective and prospective quality of life (QOL), PPI usage, and patient satisfaction data were obtained. Hernia recurrence was assessed by either barium swallow or gastroscopy. Results. 87 patients were identified in the database with a minimum of 3 months followup. There were significant improvements in QOL scores including GERD HRQL (29.13 to 4.38, P

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2356-7759; https://doaj.org/toc/2356-6124

URL الوصول: https://doaj.org/article/f3eeaa911d274606bf31f753a0c64855

المؤلفون: Brian Schloss, David Martin, Allan Beebe, Jan Klamar, Joseph D. Tobias

المصدر: The Thoracic & Cardiovascular Surgeon Reports, Vol 02, Iss 01, Pp 016-018 (2013)

مصطلحات موضوعية: pediatric, hypoxia, one-lung ventilation, Surgery, RD1-811

الوصف: Abstract To improve surgical visualization and facilitate the procedure, one-lung ventilation (OLV) is frequently used during thoracic surgery. Although generally well tolerated, the ventilation–perfusion inequality induced by OLV may lead to a decrease in oxygenation and, at times, hypoxemia. Effective treatment algorithms and strategies are necessary for the treatment of hypoxemia during OLV to ensure that the technique can be continued without interruption and allow for completion of the surgical procedure. Treatment strategies may include applying positive end expiratory pressure to the nonoperative lung, continuous positive airway pressure or low flow oxygen insufflation to the operative lung, decreasing anesthetic agents that interfere with hypoxic pulmonary vasoconstriction (HPV), or switching to total intravenous anesthesia. Although less commonly employed, α-adrenergic agonists may also improve oxygenation during OLV by augmenting HPV. We present a 12-year-old girl who developed hypoxemia during OLV, which was not corrected by the usual maneuvers. Hypoxemia was successfully treated with a phenylephrine infusion. The potential applications of α-adrenergic agonists such as phenylephrine in the treatment of hypoxemia during OLV are discussed and its physiologic basis reviewed.

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2194-7635; https://doaj.org/toc/2194-7643

URL الوصول: https://doaj.org/article/8a990a5bcc764a55b38ccea29123cb74